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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TP53

Z-value: 0.85

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Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
TP53
ENSG00000141510.11 tumor protein p53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP53hg19_v2_chr17_-_7590745_75908560.918.6e-02Click!

Activity profile of TP53 motif

Sorted Z-values of TP53 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_47551836 0.59 ENST00000253047.6
TMEM160
transmembrane protein 160
chr19_-_47735918 0.56 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr8_+_22429205 0.49 ENST00000520207.1
SORBS3
sorbin and SH3 domain containing 3
chr2_+_233734994 0.46 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr17_+_73455788 0.46 ENST00000581519.1
KIAA0195
KIAA0195
chr17_+_76210367 0.44 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr11_+_64126671 0.43 ENST00000530504.1
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr1_-_201438282 0.41 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr6_+_33378517 0.40 ENST00000428274.1
PHF1
PHD finger protein 1
chr1_+_11796177 0.40 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
AGTRAP
angiotensin II receptor-associated protein
chr1_+_11796126 0.40 ENST00000376637.3
AGTRAP
angiotensin II receptor-associated protein
chr16_-_29874211 0.37 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr11_+_64879317 0.37 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2
transmembrane 7 superfamily member 2
chr17_+_14204389 0.33 ENST00000360954.2
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr20_+_4129496 0.32 ENST00000346595.2
SMOX
spermine oxidase
chr11_+_64126614 0.32 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr22_+_21336267 0.31 ENST00000215739.8
LZTR1
leucine-zipper-like transcription regulator 1
chr11_+_64073699 0.31 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr1_+_151584544 0.29 ENST00000458013.2
ENST00000368843.3
SNX27
sorting nexin family member 27
chr11_-_44972476 0.29 ENST00000527685.1
ENST00000308212.5
TP53I11
tumor protein p53 inducible protein 11
chr16_+_2570340 0.28 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr7_+_140396946 0.28 ENST00000476470.1
ENST00000471136.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr7_+_140396756 0.28 ENST00000460088.1
ENST00000472695.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr19_+_13228917 0.27 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr17_-_61523622 0.27 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
CYB561
cytochrome b561
chr22_-_37415475 0.27 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
TST
thiosulfate sulfurtransferase (rhodanese)
chr22_+_40766582 0.27 ENST00000457767.1
ENST00000248929.9
ENST00000454798.2
SGSM3
small G protein signaling modulator 3
chr20_-_23618582 0.27 ENST00000398411.1
ENST00000376925.3
CST3
cystatin C
chr1_-_54518865 0.27 ENST00000371337.3
TMEM59
transmembrane protein 59
chr22_-_20307532 0.26 ENST00000405465.3
ENST00000248879.3
DGCR6L
DiGeorge syndrome critical region gene 6-like
chr17_+_73089382 0.26 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr19_-_42721819 0.25 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
DEDD2
death effector domain containing 2
chr7_+_140396465 0.25 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr12_-_113772835 0.25 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
SLC8B1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr16_-_31106211 0.25 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
RP11-196G11.1
VKORC1
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr16_-_29874462 0.24 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr15_-_72767490 0.24 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr19_+_54496132 0.23 ENST00000346968.2
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chr19_+_56652643 0.23 ENST00000586123.1
ZNF444
zinc finger protein 444
chr11_-_44972418 0.23 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
TP53I11
tumor protein p53 inducible protein 11
chr12_+_53895052 0.22 ENST00000552857.1
TARBP2
TAR (HIV-1) RNA binding protein 2
chr11_+_119039414 0.22 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLRX1
NLR family member X1
chr22_+_42949925 0.22 ENST00000327678.5
ENST00000340239.4
ENST00000407614.4
ENST00000335879.5
SERHL2
serine hydrolase-like 2
chr19_-_6591113 0.22 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr19_+_56653064 0.21 ENST00000593100.1
ZNF444
zinc finger protein 444
chr15_+_89164560 0.21 ENST00000379231.3
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr22_-_28392227 0.21 ENST00000431039.1
TTC28
tetratricopeptide repeat domain 28
chr10_-_105212059 0.21 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr16_-_68000717 0.21 ENST00000541864.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr17_-_45918539 0.21 ENST00000584123.1
ENST00000578323.1
ENST00000407215.3
ENST00000290216.9
SCRN2
secernin 2
chr12_+_56546363 0.21 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr17_+_18128896 0.21 ENST00000316843.4
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr11_-_44972390 0.21 ENST00000395648.3
ENST00000531928.2
TP53I11
tumor protein p53 inducible protein 11
chr7_-_75241096 0.20 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr6_+_33378738 0.20 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chr16_+_57653989 0.20 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56
G protein-coupled receptor 56
chr11_+_289155 0.20 ENST00000409655.1
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr19_-_5567842 0.20 ENST00000587632.1
TINCR
tissue differentiation-inducing non-protein coding RNA
chr16_-_31106048 0.19 ENST00000300851.6
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr11_-_44972299 0.19 ENST00000528473.1
TP53I11
tumor protein p53 inducible protein 11
chr10_-_73611046 0.19 ENST00000394934.1
ENST00000394936.3
PSAP
prosaposin
chr8_+_95731904 0.19 ENST00000522422.1
DPY19L4
dpy-19-like 4 (C. elegans)
chr1_-_209825674 0.18 ENST00000367030.3
ENST00000356082.4
LAMB3
laminin, beta 3
chr19_+_489140 0.18 ENST00000587541.1
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr11_-_73694346 0.18 ENST00000310473.3
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr19_-_1605424 0.18 ENST00000589880.1
ENST00000585671.1
ENST00000591899.3
UQCR11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr10_-_105212141 0.18 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chrX_+_192989 0.17 ENST00000399012.1
ENST00000430923.2
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr2_+_10281509 0.17 ENST00000381786.3
C2orf48
chromosome 2 open reading frame 48
chr16_+_57653854 0.17 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56
G protein-coupled receptor 56
chr1_-_156051789 0.17 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr17_-_61523535 0.17 ENST00000584031.1
ENST00000392976.1
CYB561
cytochrome b561
chr19_+_56652686 0.17 ENST00000592949.1
ZNF444
zinc finger protein 444
chr19_+_49458107 0.17 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr19_+_13988061 0.17 ENST00000339133.5
ENST00000397555.2
NANOS3
nanos homolog 3 (Drosophila)
chr20_+_62289640 0.17 ENST00000508582.2
ENST00000360203.5
ENST00000356810.4
RTEL1
regulator of telomere elongation helicase 1
chr1_-_1243392 0.17 ENST00000354700.5
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr19_-_45735138 0.17 ENST00000252482.3
EXOC3L2
exocyst complex component 3-like 2
chr19_+_56652556 0.16 ENST00000337080.3
ZNF444
zinc finger protein 444
chr11_+_62538775 0.16 ENST00000294168.3
ENST00000526261.1
TAF6L
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr9_-_135996537 0.16 ENST00000372050.3
ENST00000372047.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr11_+_289110 0.16 ENST00000409548.2
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr11_-_65626797 0.16 ENST00000525451.2
CFL1
cofilin 1 (non-muscle)
chr20_+_35234137 0.16 ENST00000344795.3
ENST00000373852.5
C20orf24
chromosome 20 open reading frame 24
chr22_-_18257178 0.16 ENST00000342111.5
BID
BH3 interacting domain death agonist
chr12_+_53895364 0.16 ENST00000552817.1
ENST00000394357.2
TARBP2
TAR (HIV-1) RNA binding protein 2
chr1_-_202936394 0.16 ENST00000367249.4
CYB5R1
cytochrome b5 reductase 1
chr15_-_30685563 0.16 ENST00000401522.3
CHRFAM7A
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
chr10_+_134000404 0.15 ENST00000338492.4
ENST00000368629.1
DPYSL4
dihydropyrimidinase-like 4
chr20_+_33759854 0.15 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr1_+_27153173 0.15 ENST00000374142.4
ZDHHC18
zinc finger, DHHC-type containing 18
chr16_-_3422283 0.15 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr12_+_53645870 0.15 ENST00000329548.4
MFSD5
major facilitator superfamily domain containing 5
chr20_-_1373606 0.15 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr16_+_2961973 0.15 ENST00000399667.2
ENST00000416288.2
ENST00000570425.1
ENST00000573525.1
FLYWCH1
FLYWCH-type zinc finger 1
chr11_+_827553 0.15 ENST00000528542.2
ENST00000450448.1
EFCAB4A
EF-hand calcium binding domain 4A
chr14_-_64971288 0.15 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr11_-_47546250 0.14 ENST00000543178.1
CELF1
CUGBP, Elav-like family member 1
chr16_-_67997947 0.14 ENST00000537830.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr20_+_4129426 0.14 ENST00000339123.6
ENST00000305958.4
ENST00000278795.3
SMOX
spermine oxidase
chr14_-_20929624 0.14 ENST00000398020.4
ENST00000250489.4
TMEM55B
transmembrane protein 55B
chr2_+_47168630 0.14 ENST00000263737.6
TTC7A
tetratricopeptide repeat domain 7A
chr22_+_38302285 0.14 ENST00000215957.6
MICALL1
MICAL-like 1
chr9_-_140115775 0.14 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr1_-_1243252 0.14 ENST00000353662.3
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr17_+_76210267 0.14 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr19_+_13229126 0.14 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr8_-_22926623 0.14 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr8_-_12293852 0.14 ENST00000262365.4
ENST00000351291.4
ENST00000309608.5
ENST00000527331.1
ENST00000532480.1
ENST00000393715.3
FAM86B2
family with sequence similarity 86, member B2
chr4_+_103422499 0.13 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chrX_-_153285251 0.13 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr17_-_14140166 0.13 ENST00000420162.2
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr17_-_7387524 0.13 ENST00000311403.4
ZBTB4
zinc finger and BTB domain containing 4
chr14_-_64970494 0.13 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chrX_-_153285395 0.13 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr12_+_53894672 0.12 ENST00000266987.2
ENST00000456234.2
TARBP2
TAR (HIV-1) RNA binding protein 2
chr1_+_116519223 0.12 ENST00000369502.1
SLC22A15
solute carrier family 22, member 15
chr7_-_72439997 0.12 ENST00000285805.3
TRIM74
tripartite motif containing 74
chr9_+_139846708 0.12 ENST00000371633.3
LCN12
lipocalin 12
chr22_-_39239987 0.12 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chr9_+_35605274 0.12 ENST00000336395.5
TESK1
testis-specific kinase 1
chr12_-_6451235 0.12 ENST00000440083.2
ENST00000162749.2
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr14_-_75078725 0.12 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr11_-_64570706 0.12 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr1_+_2477831 0.12 ENST00000606645.1
RP3-395M20.12
RP3-395M20.12
chr11_+_60699222 0.12 ENST00000536409.1
TMEM132A
transmembrane protein 132A
chrX_-_54209640 0.12 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
FAM120C
family with sequence similarity 120C
chr6_+_157802165 0.11 ENST00000414563.2
ENST00000359775.5
ZDHHC14
zinc finger, DHHC-type containing 14
chr19_+_42746927 0.11 ENST00000378108.1
AC006486.1
AC006486.1
chr7_-_100287071 0.11 ENST00000275732.5
GIGYF1
GRB10 interacting GYF protein 1
chr7_-_56101826 0.11 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr11_+_706595 0.11 ENST00000531348.1
ENST00000530636.1
EPS8L2
EPS8-like 2
chr12_-_6451186 0.11 ENST00000540022.1
ENST00000536194.1
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr10_+_11784360 0.11 ENST00000379215.4
ENST00000420401.1
ECHDC3
enoyl CoA hydratase domain containing 3
chr22_+_29279552 0.11 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr20_+_35234223 0.11 ENST00000342422.3
C20orf24
chromosome 20 open reading frame 24
chr20_+_48429233 0.11 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr7_-_74221288 0.11 ENST00000451013.2
GTF2IRD2
GTF2I repeat domain containing 2
chr19_+_2785458 0.11 ENST00000307741.6
ENST00000585338.1
THOP1
thimet oligopeptidase 1
chr22_+_37447771 0.10 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17
potassium channel tetramerization domain containing 17
chr3_-_52001448 0.10 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4
poly(rC) binding protein 4
chr19_+_18492973 0.10 ENST00000595973.2
GDF15
growth differentiation factor 15
chr17_+_20483037 0.10 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr2_+_47168313 0.10 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr19_-_44258770 0.10 ENST00000601925.1
ENST00000602222.1
ENST00000599804.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr15_+_89164520 0.10 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr5_+_141348755 0.10 ENST00000506004.1
ENST00000507291.1
RNF14
ring finger protein 14
chr11_+_36397528 0.10 ENST00000311599.5
ENST00000378867.3
PRR5L
proline rich 5 like
chr2_-_75788038 0.10 ENST00000393913.3
ENST00000410113.1
EVA1A
eva-1 homolog A (C. elegans)
chr19_+_42364313 0.10 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr19_-_42746714 0.10 ENST00000222330.3
GSK3A
glycogen synthase kinase 3 alpha
chr10_+_64564469 0.10 ENST00000373783.1
ADO
2-aminoethanethiol (cysteamine) dioxygenase
chr20_-_62680984 0.10 ENST00000340356.7
SOX18
SRY (sex determining region Y)-box 18
chr15_-_89456630 0.10 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chr2_-_242447732 0.10 ENST00000439101.1
ENST00000424537.1
ENST00000401869.1
ENST00000436402.1
STK25
serine/threonine kinase 25
chr2_-_71221942 0.10 ENST00000272438.4
TEX261
testis expressed 261
chr11_+_119038897 0.10 ENST00000454811.1
ENST00000449394.1
NLRX1
NLR family member X1
chr19_-_40931891 0.10 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr12_-_14996355 0.09 ENST00000228936.4
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr20_+_48429356 0.09 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr12_+_56546223 0.09 ENST00000550443.1
ENST00000207437.5
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr16_+_2079501 0.09 ENST00000563587.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr5_-_146833803 0.09 ENST00000512722.1
DPYSL3
dihydropyrimidinase-like 3
chr3_+_183894566 0.09 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr16_-_31105870 0.09 ENST00000394971.3
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr2_-_26205340 0.09 ENST00000264712.3
KIF3C
kinesin family member 3C
chr9_-_134406565 0.09 ENST00000372210.3
ENST00000372211.3
UCK1
uridine-cytidine kinase 1
chr2_-_242447962 0.09 ENST00000405883.3
STK25
serine/threonine kinase 25
chr17_+_18087553 0.09 ENST00000399138.4
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr19_-_44258733 0.09 ENST00000597586.1
ENST00000596714.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr19_+_42364460 0.09 ENST00000593863.1
RPS19
ribosomal protein S19
chr12_-_59314246 0.08 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr1_-_6453399 0.08 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr2_-_242447983 0.08 ENST00000426941.1
ENST00000405585.1
ENST00000420551.1
ENST00000535007.1
ENST00000429279.1
ENST00000442307.1
ENST00000403346.3
ENST00000316586.4
STK25
serine/threonine kinase 25
chr19_+_17982747 0.08 ENST00000222248.3
SLC5A5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr19_+_926000 0.08 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr16_+_30207122 0.08 ENST00000395137.2
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr1_+_116519112 0.08 ENST00000369503.4
SLC22A15
solute carrier family 22, member 15
chr19_+_827823 0.08 ENST00000233997.2
AZU1
azurocidin 1
chr15_-_102285913 0.08 ENST00000558592.1
RP11-89K11.1
Uncharacterized protein
chr9_-_134406611 0.07 ENST00000372208.3
ENST00000372215.4
UCK1
uridine-cytidine kinase 1
chr3_+_184279566 0.07 ENST00000330394.2
EPHB3
EPH receptor B3
chrX_-_70473957 0.07 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3
zinc finger, MYM-type 3
chr5_-_72861175 0.07 ENST00000504641.1
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr16_+_29467780 0.07 ENST00000395400.3
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr17_+_12859080 0.07 ENST00000583608.1
ARHGAP44
Rho GTPase activating protein 44
chr10_-_102279586 0.07 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B
SEC31 homolog B (S. cerevisiae)
chr11_+_64002292 0.07 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chrX_-_153583257 0.07 ENST00000438732.1
FLNA
filamin A, alpha
chr11_+_65222698 0.06 ENST00000309775.7
AP000769.1
Uncharacterized protein
chr19_-_2456922 0.06 ENST00000582871.1
ENST00000325327.3
LMNB2
lamin B2
chr1_-_45805752 0.06 ENST00000354383.6
ENST00000355498.2
ENST00000372100.5
ENST00000531105.1
MUTYH
mutY homolog
chr11_-_129062093 0.06 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr7_+_72742178 0.06 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr1_+_25598872 0.06 ENST00000328664.4
RHD
Rh blood group, D antigen
chr3_-_52479043 0.06 ENST00000231721.2
ENST00000475739.1
SEMA3G
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr4_-_10118348 0.06 ENST00000502702.1
WDR1
WD repeat domain 1
chr3_-_184079382 0.06 ENST00000344937.7
ENST00000423355.2
ENST00000434054.2
ENST00000457512.1
ENST00000265593.4
CLCN2
chloride channel, voltage-sensitive 2
chr7_+_100770328 0.06 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr8_-_22926526 0.06 ENST00000347739.3
ENST00000542226.1
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.3 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 0.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.5 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.2 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.5 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.2 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.1 0.2 GO:1902512 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.3 GO:0051541 negative regulation of extracellular matrix disassembly(GO:0010716) elastin metabolic process(GO:0051541)
0.0 0.8 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.2 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.3 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.2 GO:0060315 protein maturation by protein folding(GO:0022417) negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0003095 pressure natriuresis(GO:0003095) vitamin E metabolic process(GO:0042360)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.3 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0030120 ER to Golgi transport vesicle membrane(GO:0012507) vesicle coat(GO:0030120)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.8 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.2 0.5 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.1 0.4 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.4 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.5 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1