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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TLX2

Z-value: 1.99

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Transcription factors associated with TLX2

Gene Symbol Gene ID Gene Info
TLX2
ENSG00000115297.9 T cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TLX2hg19_v2_chr2_+_74741569_747416200.138.7e-01Click!

Activity profile of TLX2 motif

Sorted Z-values of TLX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_82555169 1.19 ENST00000565432.1
ENST00000427381.2
FAM154B
family with sequence similarity 154, member B
chr1_-_151762943 0.98 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH
tudor and KH domain containing
chr20_+_52824367 0.80 ENST00000371419.2
PFDN4
prefoldin subunit 4
chr6_-_31648150 0.76 ENST00000375858.3
ENST00000383237.4
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr8_+_120428546 0.75 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr3_+_69134124 0.71 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr8_-_134511587 0.71 ENST00000523855.1
ENST00000523854.1
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr6_+_84563295 0.69 ENST00000369687.1
RIPPLY2
ripply transcriptional repressor 2
chr11_-_64889252 0.68 ENST00000525297.1
ENST00000529259.1
FAU
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr1_-_155159748 0.66 ENST00000473363.2
RP11-201K10.3
RP11-201K10.3
chr16_-_28222797 0.65 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr1_-_1850697 0.65 ENST00000378598.4
ENST00000416272.1
ENST00000310991.3
TMEM52
transmembrane protein 52
chr6_+_24775641 0.65 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr10_+_35416223 0.62 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr10_+_35416090 0.61 ENST00000354759.3
CREM
cAMP responsive element modulator
chr8_-_55014336 0.60 ENST00000343231.6
LYPLA1
lysophospholipase I
chr13_+_60971427 0.59 ENST00000535286.1
ENST00000377881.2
TDRD3
tudor domain containing 3
chr17_+_41150793 0.57 ENST00000586277.1
RPL27
ribosomal protein L27
chr11_-_8615507 0.57 ENST00000431279.2
ENST00000418597.1
STK33
serine/threonine kinase 33
chr9_-_128003606 0.55 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr3_-_64253655 0.54 ENST00000498162.1
PRICKLE2
prickle homolog 2 (Drosophila)
chr10_+_103348031 0.52 ENST00000370151.4
ENST00000370147.1
ENST00000370148.2
DPCD
deleted in primary ciliary dyskinesia homolog (mouse)
chr4_-_165305086 0.51 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr16_-_3149278 0.51 ENST00000575108.1
ENST00000576483.1
ENST00000538082.2
ENST00000576985.1
ZSCAN10
zinc finger and SCAN domain containing 10
chr10_-_115933942 0.51 ENST00000369285.3
ENST00000369287.3
ENST00000369286.1
C10orf118
chromosome 10 open reading frame 118
chr10_+_88718314 0.50 ENST00000348795.4
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr18_+_56531584 0.50 ENST00000590287.1
ZNF532
zinc finger protein 532
chr14_-_54955721 0.50 ENST00000554908.1
GMFB
glia maturation factor, beta
chr10_+_88718397 0.49 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr4_+_165675197 0.49 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr6_-_52109335 0.49 ENST00000336123.4
IL17F
interleukin 17F
chr19_+_55999916 0.49 ENST00000587166.1
ENST00000389623.6
SSC5D
scavenger receptor cysteine rich domain containing (5 domains)
chr1_-_151762900 0.46 ENST00000440583.2
TDRKH
tudor and KH domain containing
chr11_-_64510409 0.46 ENST00000394429.1
ENST00000394428.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_+_24018269 0.46 ENST00000374550.3
RPL11
ribosomal protein L11
chr7_+_6414128 0.46 ENST00000348035.4
ENST00000356142.4
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr3_-_149051444 0.46 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr20_+_56884752 0.46 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr3_-_179322416 0.45 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr3_-_129279894 0.45 ENST00000506979.1
PLXND1
plexin D1
chr22_+_42017987 0.44 ENST00000405506.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr18_-_61034416 0.43 ENST00000326575.5
ENST00000592327.1
KDSR
3-ketodihydrosphingosine reductase
chrX_-_38186811 0.43 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr3_-_42814708 0.43 ENST00000310232.6
CCDC13
coiled-coil domain containing 13
chr16_+_81478775 0.43 ENST00000537098.3
CMIP
c-Maf inducing protein
chr17_+_66509019 0.43 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr11_+_69924639 0.42 ENST00000538023.1
ENST00000398543.2
ANO1
anoctamin 1, calcium activated chloride channel
chr11_-_102323740 0.42 ENST00000398136.2
TMEM123
transmembrane protein 123
chr2_-_219146839 0.42 ENST00000425694.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr1_+_92764522 0.42 ENST00000610020.1
RPAP2
RNA polymerase II associated protein 2
chr1_+_43148625 0.42 ENST00000436427.1
YBX1
Y box binding protein 1
chr3_+_69134080 0.41 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr11_-_123065989 0.41 ENST00000448775.2
CLMP
CXADR-like membrane protein
chr16_-_24942411 0.41 ENST00000571843.1
ARHGAP17
Rho GTPase activating protein 17
chr16_+_53412368 0.41 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr19_+_58193388 0.40 ENST00000596085.1
ENST00000594684.1
ZNF551
AC003006.7
zinc finger protein 551
Uncharacterized protein
chr3_-_182880541 0.40 ENST00000470251.1
ENST00000265598.3
LAMP3
lysosomal-associated membrane protein 3
chr12_+_104324112 0.39 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr14_-_74296806 0.39 ENST00000555539.1
RP5-1021I20.2
RP5-1021I20.2
chrX_-_151999269 0.39 ENST00000370277.3
CETN2
centrin, EF-hand protein, 2
chrX_-_77395186 0.39 ENST00000341864.5
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr5_-_150080472 0.39 ENST00000521464.1
ENST00000518917.1
ENST00000447771.2
ENST00000540000.1
ENST00000199814.4
RBM22
RNA binding motif protein 22
chr12_+_27091426 0.39 ENST00000546072.1
ENST00000327214.5
FGFR1OP2
FGFR1 oncogene partner 2
chr12_-_11002063 0.39 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr13_+_60971080 0.39 ENST00000377894.2
TDRD3
tudor domain containing 3
chr11_-_34938039 0.38 ENST00000395787.3
APIP
APAF1 interacting protein
chr19_+_47104553 0.38 ENST00000598871.1
ENST00000594523.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr1_+_231114795 0.38 ENST00000310256.2
ENST00000366658.2
ENST00000450711.1
ENST00000435927.1
ARV1
ARV1 homolog (S. cerevisiae)
chr17_+_42925270 0.38 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr9_-_115480303 0.38 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INIP
INTS3 and NABP interacting protein
chr4_+_39046615 0.37 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr14_+_35452104 0.37 ENST00000216774.6
ENST00000546080.1
SRP54
signal recognition particle 54kDa
chr2_+_192543153 0.37 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr1_-_235324772 0.37 ENST00000408888.3
RBM34
RNA binding motif protein 34
chr20_+_2795609 0.36 ENST00000554164.1
ENST00000380593.4
TMEM239
TMEM239
transmembrane protein 239
CDNA FLJ26142 fis, clone TST04526; Transmembrane protein 239; Uncharacterized protein
chr20_+_44746939 0.36 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr20_+_2795626 0.36 ENST00000603872.1
ENST00000380589.4
C20orf141
chromosome 20 open reading frame 141
chr12_-_99038732 0.36 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP
IKBKB interacting protein
chr9_-_80645520 0.36 ENST00000411677.1
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr11_-_134123142 0.36 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chr1_+_24019099 0.36 ENST00000443624.1
ENST00000458455.1
RPL11
ribosomal protein L11
chr14_+_71788096 0.35 ENST00000557151.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr11_+_8704298 0.35 ENST00000531978.1
ENST00000524496.1
ENST00000532359.1
ENST00000530022.1
RPL27A
ribosomal protein L27a
chr5_+_96077888 0.35 ENST00000509259.1
ENST00000503828.1
CAST
calpastatin
chr12_+_64798826 0.35 ENST00000540203.1
XPOT
exportin, tRNA
chr1_-_154832316 0.35 ENST00000361147.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr8_+_57124245 0.35 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
CHCHD7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr11_+_18344106 0.34 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr1_+_93297582 0.34 ENST00000370321.3
RPL5
ribosomal protein L5
chr14_+_54863682 0.34 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
CDKN3
cyclin-dependent kinase inhibitor 3
chr10_-_124768300 0.34 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr8_+_103540983 0.34 ENST00000523572.1
KB-1980E6.3
Uncharacterized protein
chr2_+_219433588 0.34 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr11_+_93474757 0.34 ENST00000528288.1
C11orf54
chromosome 11 open reading frame 54
chr19_-_36342739 0.34 ENST00000378910.5
ENST00000353632.6
NPHS1
nephrosis 1, congenital, Finnish type (nephrin)
chr14_+_89029866 0.34 ENST00000557693.1
ENST00000555120.1
ZC3H14
zinc finger CCCH-type containing 14
chr14_+_54863667 0.34 ENST00000335183.6
CDKN3
cyclin-dependent kinase inhibitor 3
chr1_-_92764523 0.33 ENST00000370360.3
ENST00000534881.1
GLMN
glomulin, FKBP associated protein
chr11_+_18343800 0.33 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr11_-_62572901 0.33 ENST00000439713.2
ENST00000531131.1
ENST00000530875.1
ENST00000531709.2
ENST00000294172.2
NXF1
nuclear RNA export factor 1
chr15_-_82555000 0.33 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
EFTUD1
elongation factor Tu GTP binding domain containing 1
chr16_+_19183671 0.33 ENST00000562711.2
SYT17
synaptotagmin XVII
chr17_-_48785216 0.33 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr3_+_148847371 0.32 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr13_-_21348050 0.32 ENST00000382754.4
N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr9_-_88896977 0.32 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr1_+_207494853 0.32 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr12_-_89918982 0.32 ENST00000549504.1
POC1B
POC1 centriolar protein B
chr11_+_34938119 0.31 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX
pyruvate dehydrogenase complex, component X
chr16_+_15744078 0.31 ENST00000396354.1
ENST00000570727.1
NDE1
nudE neurodevelopment protein 1
chr14_-_67859422 0.31 ENST00000556532.1
PLEK2
pleckstrin 2
chr14_+_35452169 0.31 ENST00000555557.1
SRP54
signal recognition particle 54kDa
chr6_-_10115007 0.31 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr8_+_74903580 0.31 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr17_-_27278304 0.31 ENST00000577226.1
PHF12
PHD finger protein 12
chr2_-_63815628 0.31 ENST00000409562.3
WDPCP
WD repeat containing planar cell polarity effector
chr16_-_68269971 0.31 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr4_-_147443043 0.31 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
SLC10A7
solute carrier family 10, member 7
chr12_-_95611149 0.30 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr11_-_34937858 0.30 ENST00000278359.5
APIP
APAF1 interacting protein
chr21_-_34852304 0.30 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr12_-_122107549 0.30 ENST00000355329.3
MORN3
MORN repeat containing 3
chr19_-_6670128 0.30 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr12_-_113658826 0.30 ENST00000546692.1
IQCD
IQ motif containing D
chr14_-_36789783 0.30 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MBIP
MAP3K12 binding inhibitory protein 1
chr4_-_147442982 0.30 ENST00000511374.1
ENST00000264986.3
SLC10A7
solute carrier family 10, member 7
chr4_-_147442817 0.30 ENST00000507030.1
SLC10A7
solute carrier family 10, member 7
chr16_-_28192360 0.30 ENST00000570033.1
XPO6
exportin 6
chr19_+_58193337 0.29 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
ZNF551
zinc finger protein 551
chr14_+_50779029 0.29 ENST00000245448.6
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr3_-_12883026 0.29 ENST00000396953.2
ENST00000457131.1
ENST00000435983.1
ENST00000273223.6
ENST00000396957.1
ENST00000429711.2
RPL32
ribosomal protein L32
chr10_-_123687431 0.29 ENST00000423243.1
ATE1
arginyltransferase 1
chr8_-_141728760 0.29 ENST00000430260.2
PTK2
protein tyrosine kinase 2
chr3_+_118892411 0.29 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chr7_+_155090271 0.29 ENST00000476756.1
INSIG1
insulin induced gene 1
chr2_-_44065889 0.29 ENST00000543989.1
ENST00000405322.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr19_-_51920952 0.28 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr2_+_63816126 0.28 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr12_-_33049690 0.28 ENST00000070846.6
ENST00000340811.4
PKP2
plakophilin 2
chr1_-_185126037 0.28 ENST00000367506.5
ENST00000367504.3
TRMT1L
tRNA methyltransferase 1 homolog (S. cerevisiae)-like
chr2_+_192543694 0.28 ENST00000435931.1
NABP1
nucleic acid binding protein 1
chr14_-_36789865 0.28 ENST00000416007.4
MBIP
MAP3K12 binding inhibitory protein 1
chr10_-_74927810 0.28 ENST00000372979.4
ENST00000430082.2
ENST00000454759.2
ENST00000413026.1
ENST00000453402.1
ECD
ecdysoneless homolog (Drosophila)
chr2_+_10183651 0.28 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr8_-_131455835 0.28 ENST00000518721.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr15_+_82555125 0.28 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr12_-_48119301 0.28 ENST00000545824.2
ENST00000422538.3
ENDOU
endonuclease, polyU-specific
chr2_-_74555350 0.28 ENST00000444570.1
SLC4A5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr5_-_133968459 0.28 ENST00000505758.1
ENST00000439578.1
ENST00000502286.1
SAR1B
SAR1 homolog B (S. cerevisiae)
chr1_+_222885884 0.27 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chr5_-_133968529 0.27 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr1_+_171227069 0.27 ENST00000354841.4
FMO1
flavin containing monooxygenase 1
chr20_+_42839722 0.27 ENST00000442383.1
ENST00000435163.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr8_+_86376081 0.27 ENST00000285379.5
CA2
carbonic anhydrase II
chr16_-_16317321 0.27 ENST00000205557.7
ENST00000575728.1
ABCC6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr6_+_111303218 0.27 ENST00000441448.2
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr10_-_60027642 0.26 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr7_-_131241361 0.26 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr1_+_26872324 0.26 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr4_+_17812525 0.26 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr16_-_28223166 0.26 ENST00000304658.5
XPO6
exportin 6
chr19_-_51920873 0.26 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr17_-_4448361 0.26 ENST00000572759.1
MYBBP1A
MYB binding protein (P160) 1a
chr12_+_27091316 0.26 ENST00000229395.3
FGFR1OP2
FGFR1 oncogene partner 2
chr11_-_57298187 0.26 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
TIMM10
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr3_-_43663389 0.26 ENST00000444344.1
ENST00000456438.1
ENST00000350459.4
ENST00000396091.3
ENST00000451430.2
ENST00000428472.1
ENST00000414522.2
ANO10
anoctamin 10
chr2_-_169887827 0.26 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr11_+_35160709 0.26 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44
CD44 molecule (Indian blood group)
chr3_-_45837959 0.26 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr1_+_35734616 0.26 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr3_-_45838011 0.26 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chrX_+_153665248 0.25 ENST00000447750.2
GDI1
GDP dissociation inhibitor 1
chr6_-_127664683 0.25 ENST00000528402.1
ENST00000454591.2
ECHDC1
enoyl CoA hydratase domain containing 1
chr11_+_93474786 0.25 ENST00000331239.4
ENST00000533585.1
ENST00000528099.1
ENST00000354421.3
ENST00000540113.1
ENST00000530620.1
ENST00000527003.1
ENST00000531650.1
ENST00000530279.1
C11orf54
chromosome 11 open reading frame 54
chr12_-_27091183 0.25 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
ASUN
asunder spermatogenesis regulator
chr14_-_92588013 0.25 ENST00000553514.1
ENST00000605997.1
NDUFB1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
chrX_-_55020511 0.25 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_+_169659121 0.25 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking
chr15_-_38856836 0.25 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr19_+_52264449 0.25 ENST00000599326.1
ENST00000598953.1
FPR2
formyl peptide receptor 2
chr3_-_43663519 0.25 ENST00000427171.1
ENST00000292246.3
ANO10
anoctamin 10
chr10_+_124030819 0.25 ENST00000260723.4
ENST00000368994.2
BTBD16
BTB (POZ) domain containing 16
chr11_-_85780853 0.25 ENST00000531930.1
ENST00000528398.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr7_-_120497178 0.24 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr1_-_224033596 0.24 ENST00000391878.2
ENST00000343537.7
TP53BP2
tumor protein p53 binding protein, 2
chr20_+_42839600 0.24 ENST00000439943.1
ENST00000437730.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr3_-_149051194 0.24 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr10_+_35415978 0.24 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM
cAMP responsive element modulator
chr11_-_102323489 0.24 ENST00000361236.3
TMEM123
transmembrane protein 123
chr18_+_13726645 0.24 ENST00000543302.2
ENST00000383314.2
ENST00000535051.1
ENST00000592764.1
ENST00000591746.1
RNMT
RNA (guanine-7-) methyltransferase
chr14_+_54863739 0.24 ENST00000541304.1
CDKN3
cyclin-dependent kinase inhibitor 3
chr1_+_151030234 0.24 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr18_+_56532100 0.24 ENST00000588456.1
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr10_-_73975657 0.24 ENST00000394919.1
ENST00000526751.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr16_+_74330673 0.24 ENST00000219313.4
ENST00000540379.1
ENST00000567958.1
ENST00000568615.2
PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr3_+_142315294 0.24 ENST00000464320.1
PLS1
plastin 1
chr3_+_108308559 0.23 ENST00000486815.1
DZIP3
DAZ interacting zinc finger protein 3
chr4_-_111558135 0.23 ENST00000394598.2
ENST00000394595.3
PITX2
paired-like homeodomain 2
chr6_-_31550192 0.23 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr21_-_16437126 0.23 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 0.6 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.2 0.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.7 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.2 0.7 GO:0016598 protein arginylation(GO:0016598)
0.2 0.5 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 0.8 GO:1990523 bone regeneration(GO:1990523)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 1.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.5 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.4 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.1 0.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.3 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.5 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.1 0.2 GO:0001757 somite specification(GO:0001757)
0.1 0.7 GO:0070269 pyroptosis(GO:0070269)
0.1 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.4 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 1.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.4 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045) positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.3 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.5 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.2 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.2 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.3 GO:0045110 adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496)
0.1 0.3 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.6 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.3 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.2 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.3 GO:0003165 Purkinje myocyte development(GO:0003165)
0.1 0.2 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.6 GO:0021678 third ventricle development(GO:0021678)
0.0 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.3 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.5 GO:0015824 proline transport(GO:0015824)
0.0 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.3 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.6 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.2 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:1903061 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.6 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
0.0 1.0 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.5 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 1.1 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.3 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:0019254 amino-acid betaine catabolic process(GO:0006579) carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.4 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.4 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0048733 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) sebaceous gland development(GO:0048733)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0009595 detection of biotic stimulus(GO:0009595)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0071547 piP-body(GO:0071547)
0.2 0.6 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1 1.0 GO:0070876 SOSS complex(GO:0070876)
0.1 0.8 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.4 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.4 GO:0071942 XPC complex(GO:0071942)
0.1 0.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.4 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 0.7 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.9 GO:0005921 gap junction(GO:0005921)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.2 0.7 GO:0004057 arginyltransferase activity(GO:0004057)
0.1 1.2 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.4 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.1 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 0.3 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.6 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.3 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.6 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.3 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.3 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 1.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling