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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TLX1_NFIC

Z-value: 0.71

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Transcription factors associated with TLX1_NFIC

Gene Symbol Gene ID Gene Info
TLX1
ENSG00000107807.8 T cell leukemia homeobox 1
NFIC
ENSG00000141905.13 nuclear factor I C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIChg19_v2_chr19_+_3366547_33666190.871.3e-01Click!

Activity profile of TLX1_NFIC motif

Sorted Z-values of TLX1_NFIC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_90735145 0.82 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr11_-_66313699 0.44 ENST00000526986.1
ENST00000310442.3
ZDHHC24
zinc finger, DHHC-type containing 24
chr11_-_118789613 0.41 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr6_-_33663474 0.33 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr19_+_677885 0.32 ENST00000591552.2
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr20_-_60942361 0.31 ENST00000252999.3
LAMA5
laminin, alpha 5
chr11_+_22646739 0.29 ENST00000428556.2
AC103801.2
AC103801.2
chr22_-_46450024 0.28 ENST00000396008.2
ENST00000333761.1
C22orf26
chromosome 22 open reading frame 26
chr7_-_75241096 0.28 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr7_-_37024665 0.25 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr7_-_5463175 0.25 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr22_-_30960876 0.23 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr20_-_44519839 0.23 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr1_+_27153173 0.22 ENST00000374142.4
ZDHHC18
zinc finger, DHHC-type containing 18
chr11_-_65325664 0.21 ENST00000301873.5
LTBP3
latent transforming growth factor beta binding protein 3
chr15_+_75335604 0.21 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr16_-_19896150 0.21 ENST00000570142.1
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr16_+_30662085 0.21 ENST00000569864.1
PRR14
proline rich 14
chr5_-_176923846 0.20 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr19_+_40871734 0.20 ENST00000359274.5
PLD3
phospholipase D family, member 3
chr5_-_176923803 0.20 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr7_+_22766766 0.19 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr16_+_30662050 0.19 ENST00000568754.1
PRR14
proline rich 14
chrX_-_40005865 0.19 ENST00000412952.1
BCOR
BCL6 corepressor
chr1_+_33231268 0.18 ENST00000373480.1
KIAA1522
KIAA1522
chr4_+_110834033 0.18 ENST00000509793.1
ENST00000265171.5
EGF
epidermal growth factor
chr22_+_19706958 0.18 ENST00000395109.2
SEPT5
septin 5
chr6_-_30043539 0.18 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr7_+_143078652 0.18 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr17_+_1633755 0.18 ENST00000545662.1
WDR81
WD repeat domain 81
chr16_+_57662419 0.18 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr9_-_130616915 0.18 ENST00000344849.3
ENG
endoglin
chr16_-_2264779 0.17 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr21_+_46875424 0.17 ENST00000359759.4
COL18A1
collagen, type XVIII, alpha 1
chr22_+_41763274 0.17 ENST00000406644.3
TEF
thyrotrophic embryonic factor
chr20_+_33759854 0.17 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr20_-_60942326 0.17 ENST00000370677.3
ENST00000370692.3
LAMA5
laminin, alpha 5
chr21_+_46875395 0.17 ENST00000355480.5
COL18A1
collagen, type XVIII, alpha 1
chr4_+_86748898 0.16 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr11_+_45825616 0.16 ENST00000442528.2
ENST00000456334.1
ENST00000526817.1
SLC35C1
solute carrier family 35 (GDP-fucose transporter), member C1
chr10_+_102758105 0.16 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr9_-_130487143 0.16 ENST00000419060.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr1_+_113217309 0.16 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr8_+_61822605 0.16 ENST00000526936.1
AC022182.1
AC022182.1
chr7_+_150065278 0.16 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr1_+_113217043 0.16 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr21_+_17792672 0.16 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr11_-_57089671 0.15 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr12_+_6644443 0.15 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chrX_-_128788914 0.15 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr9_-_130617029 0.15 ENST00000373203.4
ENG
endoglin
chr1_-_229569834 0.15 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr1_+_113217073 0.15 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr8_-_21988558 0.15 ENST00000312841.8
HR
hair growth associated
chrX_-_54522558 0.15 ENST00000375135.3
FGD1
FYVE, RhoGEF and PH domain containing 1
chr8_-_42065075 0.15 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT
plasminogen activator, tissue
chr11_-_62313090 0.15 ENST00000528508.1
ENST00000533365.1
AHNAK
AHNAK nucleoprotein
chr19_+_3708338 0.15 ENST00000590545.1
TJP3
tight junction protein 3
chr17_+_77030267 0.15 ENST00000581774.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr1_+_113217345 0.15 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr11_+_74862140 0.15 ENST00000525650.1
ENST00000454962.2
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr17_+_73089382 0.15 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr8_-_145331153 0.14 ENST00000377412.4
KM-PA-2
KM-PA-2 protein; Uncharacterized protein
chr12_-_54813229 0.14 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr8_+_101349823 0.14 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr1_+_79086088 0.14 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr21_+_33784957 0.14 ENST00000401402.3
ENST00000382699.3
EVA1C
eva-1 homolog C (C. elegans)
chr11_-_65325430 0.14 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr16_+_30751953 0.14 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr2_-_25475120 0.14 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr22_+_50639408 0.14 ENST00000380903.2
SELO
Selenoprotein O
chr2_-_233877912 0.14 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr1_+_110453203 0.13 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr1_-_161168834 0.13 ENST00000367995.3
ENST00000367996.5
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr8_-_145701718 0.13 ENST00000377317.4
FOXH1
forkhead box H1
chr11_+_74862032 0.13 ENST00000289575.5
ENST00000341411.4
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr19_-_40324255 0.13 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr11_-_64764435 0.13 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr11_-_65149422 0.13 ENST00000526432.1
ENST00000527174.1
SLC25A45
solute carrier family 25, member 45
chr17_+_37894570 0.13 ENST00000394211.3
GRB7
growth factor receptor-bound protein 7
chr16_+_23765948 0.13 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr2_+_27071292 0.12 ENST00000431402.1
ENST00000434719.1
DPYSL5
dihydropyrimidinase-like 5
chr20_-_50722183 0.12 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr10_+_106034884 0.12 ENST00000369707.2
ENST00000429569.2
GSTO2
glutathione S-transferase omega 2
chr11_+_67776012 0.12 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr11_+_74862100 0.12 ENST00000532236.1
ENST00000531756.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr17_-_73874654 0.12 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr14_-_101014435 0.12 ENST00000554356.1
BEGAIN
brain-enriched guanylate kinase-associated
chr20_+_58571419 0.12 ENST00000244049.3
ENST00000350849.6
ENST00000456106.1
CDH26
cadherin 26
chr7_-_100065686 0.12 ENST00000423266.1
ENST00000456330.1
TSC22D4
TSC22 domain family, member 4
chr1_-_44497118 0.12 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr17_+_7461613 0.12 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_+_13349711 0.11 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr11_-_62457371 0.11 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr16_-_67450325 0.11 ENST00000348579.2
ZDHHC1
zinc finger, DHHC-type containing 1
chr14_-_85996332 0.11 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr22_+_45072925 0.11 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr21_+_33784670 0.11 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr7_-_5569588 0.11 ENST00000417101.1
ACTB
actin, beta
chr19_+_45312347 0.10 ENST00000270233.6
ENST00000591520.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr19_+_42788172 0.10 ENST00000160740.3
CIC
capicua transcriptional repressor
chr5_+_150020214 0.10 ENST00000307662.4
SYNPO
synaptopodin
chr11_-_67771513 0.10 ENST00000227471.2
UNC93B1
unc-93 homolog B1 (C. elegans)
chr11_+_64126614 0.10 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr13_+_113030658 0.10 ENST00000414180.1
ENST00000443541.1
SPACA7
sperm acrosome associated 7
chr14_+_85996471 0.10 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr16_-_19896220 0.10 ENST00000562469.1
ENST00000300571.2
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr6_-_26056695 0.10 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr17_+_74372662 0.10 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr1_+_240177627 0.10 ENST00000447095.1
FMN2
formin 2
chr15_+_89182156 0.10 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_+_42429493 0.10 ENST00000586242.1
GRN
granulin
chr2_+_234296792 0.10 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr17_+_72428218 0.10 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr19_+_10397648 0.09 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr12_-_56105880 0.09 ENST00000557257.1
ITGA7
integrin, alpha 7
chr11_+_45825896 0.09 ENST00000314134.3
SLC35C1
solute carrier family 35 (GDP-fucose transporter), member C1
chr5_-_111093081 0.09 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chrX_+_48681768 0.09 ENST00000430858.1
HDAC6
histone deacetylase 6
chr17_-_45899126 0.09 ENST00000007414.3
ENST00000392507.3
OSBPL7
oxysterol binding protein-like 7
chr12_+_113682066 0.09 ENST00000392569.4
ENST00000552542.1
TPCN1
two pore segment channel 1
chr9_-_139915246 0.09 ENST00000470535.1
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr14_+_85996507 0.08 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_-_200992827 0.08 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr5_+_154092396 0.08 ENST00000336314.4
LARP1
La ribonucleoprotein domain family, member 1
chr14_+_105939276 0.08 ENST00000483017.3
CRIP2
cysteine-rich protein 2
chr16_+_57662138 0.08 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr2_+_219246746 0.08 ENST00000233202.6
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr11_+_71938925 0.08 ENST00000538751.1
INPPL1
inositol polyphosphate phosphatase-like 1
chr11_+_64126671 0.08 ENST00000530504.1
RPS6KA4
ribosomal protein S6 kinase, 90kDa, polypeptide 4
chrX_+_52513455 0.08 ENST00000446098.1
XAGE1C
X antigen family, member 1C
chr17_+_38599693 0.08 ENST00000542955.1
ENST00000269593.4
IGFBP4
insulin-like growth factor binding protein 4
chr19_-_11450249 0.08 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chrX_-_52531609 0.08 ENST00000438079.1
XAGE1D
X antigen family, member 1D
chr12_+_53491220 0.08 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chrX_+_52240504 0.08 ENST00000399805.2
XAGE1B
X antigen family, member 1B
chr19_+_4007644 0.08 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr11_-_72414256 0.08 ENST00000427971.2
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_-_151345159 0.08 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
SELENBP1
selenium binding protein 1
chr9_+_124030338 0.07 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
GSN
gelsolin
chr5_-_115872124 0.07 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_-_52258669 0.07 ENST00000441417.1
XAGE1A
X antigen family, member 1A
chr3_-_139396787 0.07 ENST00000296202.7
ENST00000509291.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr15_-_68724490 0.07 ENST00000315757.7
ENST00000423218.2
ITGA11
integrin, alpha 11
chr15_+_63682335 0.07 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1
RP11-321G12.1
chr11_+_1151573 0.07 ENST00000534821.1
ENST00000356191.2
MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr19_+_17579556 0.07 ENST00000442725.1
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr9_+_135037334 0.07 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2
netrin G2
chr5_+_140855495 0.07 ENST00000308177.3
PCDHGC3
protocadherin gamma subfamily C, 3
chr6_-_28321971 0.07 ENST00000396838.2
ENST00000426434.1
ENST00000434036.1
ENST00000439628.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr2_-_166930131 0.07 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr19_+_50380682 0.07 ENST00000221543.5
TBC1D17
TBC1 domain family, member 17
chr9_-_25678856 0.07 ENST00000358022.3
TUSC1
tumor suppressor candidate 1
chr1_+_33231221 0.07 ENST00000294521.3
KIAA1522
KIAA1522
chr8_+_94752349 0.07 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr1_+_45274154 0.07 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr16_+_57653854 0.07 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56
G protein-coupled receptor 56
chr16_+_2285817 0.07 ENST00000564065.1
DNASE1L2
deoxyribonuclease I-like 2
chr12_+_98987369 0.07 ENST00000401722.3
ENST00000188376.5
ENST00000228318.3
ENST00000551917.1
ENST00000548046.1
ENST00000552981.1
ENST00000551265.1
ENST00000550695.1
ENST00000547534.1
ENST00000549338.1
ENST00000548847.1
SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr17_+_37894179 0.07 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
GRB7
growth factor receptor-bound protein 7
chr7_-_27187393 0.07 ENST00000222728.3
HOXA6
homeobox A6
chr6_-_39197226 0.07 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr1_+_155146318 0.07 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr20_+_9049742 0.06 ENST00000437503.1
PLCB4
phospholipase C, beta 4
chr14_+_75746664 0.06 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chrX_+_49126294 0.06 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr19_-_50380536 0.06 ENST00000391832.3
ENST00000391834.2
ENST00000344175.5
AKT1S1
AKT1 substrate 1 (proline-rich)
chr19_-_8675559 0.06 ENST00000597188.1
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chrX_-_53310791 0.06 ENST00000375365.2
IQSEC2
IQ motif and Sec7 domain 2
chrX_+_2746818 0.06 ENST00000398806.3
GYG2
glycogenin 2
chr11_-_71751715 0.06 ENST00000535947.1
NUMA1
nuclear mitotic apparatus protein 1
chr8_-_22014255 0.06 ENST00000424267.2
LGI3
leucine-rich repeat LGI family, member 3
chr5_+_150020240 0.06 ENST00000519664.1
SYNPO
synaptopodin
chr20_+_44034804 0.06 ENST00000357275.2
ENST00000372720.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr16_+_2198604 0.06 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr7_+_143079000 0.06 ENST00000392910.2
ZYX
zyxin
chr8_-_94752946 0.06 ENST00000519109.1
RBM12B
RNA binding motif protein 12B
chr19_+_45312310 0.06 ENST00000589651.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chrX_-_153744507 0.06 ENST00000442929.1
ENST00000426266.1
ENST00000359889.5
ENST00000369641.3
ENST00000447601.2
ENST00000434658.2
FAM3A
family with sequence similarity 3, member A
chr6_-_31550192 0.06 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr2_+_7017796 0.06 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr1_+_33219592 0.06 ENST00000373481.3
KIAA1522
KIAA1522
chr6_-_34524093 0.05 ENST00000544425.1
SPDEF
SAM pointed domain containing ETS transcription factor
chr17_+_7461849 0.05 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr7_-_81399438 0.05 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr15_-_93199069 0.05 ENST00000327355.5
FAM174B
family with sequence similarity 174, member B
chr8_-_42065187 0.05 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT
plasminogen activator, tissue
chr1_-_44497024 0.05 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr6_-_34524049 0.05 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chr2_+_27071045 0.05 ENST00000401478.1
DPYSL5
dihydropyrimidinase-like 5
chr12_+_48513009 0.05 ENST00000359794.5
ENST00000551339.1
ENST00000395233.2
ENST00000548345.1
PFKM
phosphofructokinase, muscle
chr7_+_150758304 0.05 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr16_+_30662184 0.05 ENST00000300835.4
PRR14
proline rich 14
chr19_+_10397621 0.05 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr11_-_71752571 0.05 ENST00000544238.1
NUMA1
nuclear mitotic apparatus protein 1
chr16_-_8962200 0.05 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr17_+_48503519 0.05 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
ACSF2
acyl-CoA synthetase family member 2
chr6_-_43595039 0.05 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr20_+_44034676 0.05 ENST00000372723.3
ENST00000372722.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr18_-_52989525 0.05 ENST00000457482.3
TCF4
transcription factor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX1_NFIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.3 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.4 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.6 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.2 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.1 0.3 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.2 GO:0044533 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.0 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.1 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0061760 antifungal humoral response(GO:0019732) antifungal innate immune response(GO:0061760)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:1901291 negative regulation of double-strand break repair via single-strand annealing(GO:1901291)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:1902023 L-arginine import(GO:0043091) divalent metal ion export(GO:0070839) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.0 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.0 GO:1904647 response to rotenone(GO:1904647)
0.0 0.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.5 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.0 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005055 laminin receptor activity(GO:0005055)
0.1 0.3 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling