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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for THRA_RXRB

Z-value: 1.16

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Transcription factors associated with THRA_RXRB

Gene Symbol Gene ID Gene Info
THRA
ENSG00000126351.8 thyroid hormone receptor alpha
RXRB
ENSG00000204231.6 retinoid X receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RXRBhg19_v2_chr6_-_33168391_33168465-0.999.0e-03Click!
THRAhg19_v2_chr17_+_38219063_38219154-0.841.6e-01Click!

Activity profile of THRA_RXRB motif

Sorted Z-values of THRA_RXRB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_49467232 1.22 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
CTD-2639E6.9
chr1_-_150693318 0.82 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chr12_+_57854274 0.74 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr1_-_150693305 0.58 ENST00000368987.1
HORMAD1
HORMA domain containing 1
chr19_-_39826639 0.58 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr17_-_15496722 0.53 ENST00000472534.1
CDRT1
CMT1A duplicated region transcript 1
chr8_-_99954788 0.48 ENST00000523601.1
STK3
serine/threonine kinase 3
chr2_+_230787201 0.44 ENST00000283946.3
FBXO36
F-box protein 36
chr3_+_14989186 0.44 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr10_+_76586348 0.44 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr5_+_172332220 0.43 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr7_-_151433393 0.42 ENST00000492843.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr7_-_151433342 0.42 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr5_+_162887556 0.39 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR
hyaluronan-mediated motility receptor (RHAMM)
chr9_-_114246332 0.39 ENST00000602978.1
KIAA0368
KIAA0368
chr10_+_26986582 0.38 ENST00000376215.5
ENST00000376203.5
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr1_+_178482262 0.37 ENST00000367641.3
ENST00000367639.1
TEX35
testis expressed 35
chr12_-_96184533 0.35 ENST00000343702.4
ENST00000344911.4
NTN4
netrin 4
chr1_+_229440129 0.33 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr15_-_45422056 0.32 ENST00000267803.4
ENST00000559014.1
ENST00000558851.1
ENST00000559988.1
ENST00000558996.1
ENST00000558422.1
ENST00000559226.1
ENST00000558326.1
ENST00000558377.1
ENST00000559644.1
DUOXA1
dual oxidase maturation factor 1
chr19_-_10450328 0.32 ENST00000160262.5
ICAM3
intercellular adhesion molecule 3
chr19_-_10450287 0.31 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr19_-_49565254 0.30 ENST00000593537.1
NTF4
neurotrophin 4
chr5_-_162887071 0.29 ENST00000302764.4
NUDCD2
NudC domain containing 2
chr11_-_73720276 0.29 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr14_-_58893832 0.29 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr4_+_48343339 0.29 ENST00000264313.6
SLAIN2
SLAIN motif family, member 2
chr16_+_85942594 0.28 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr16_-_72206034 0.28 ENST00000537465.1
ENST00000237353.10
PMFBP1
polyamine modulated factor 1 binding protein 1
chr2_-_192016276 0.28 ENST00000413064.1
STAT4
signal transducer and activator of transcription 4
chr2_-_177684007 0.27 ENST00000451851.1
AC092162.1
AC092162.1
chr1_-_242612779 0.27 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr14_-_55369525 0.27 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1
GTP cyclohydrolase 1
chr2_-_230786679 0.27 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
TRIP12
thyroid hormone receptor interactor 12
chr14_-_89021077 0.27 ENST00000556564.1
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr15_-_80215984 0.27 ENST00000485386.1
ENST00000479961.1
ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr22_-_42486747 0.27 ENST00000602404.1
NDUFA6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chr12_-_95510743 0.26 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr3_-_194207388 0.26 ENST00000457986.1
ATP13A3
ATPase type 13A3
chr17_+_48046671 0.26 ENST00000505318.2
DLX4
distal-less homeobox 4
chr3_-_179322416 0.26 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chrX_-_129299638 0.26 ENST00000535724.1
ENST00000346424.2
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr20_+_19870167 0.26 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr15_+_44084503 0.26 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2
small EDRK-rich factor 2
chr9_-_114246635 0.25 ENST00000338205.5
KIAA0368
KIAA0368
chr20_-_56884489 0.25 ENST00000334187.8
ENST00000244070.3
PPP4R1L
protein phosphatase 4, regulatory subunit 1-like
chr21_+_17566643 0.25 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr18_-_19748379 0.25 ENST00000579431.1
GATA6-AS1
GATA6 antisense RNA 1 (head to head)
chr22_+_17082732 0.25 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr1_-_38218577 0.25 ENST00000540011.1
EPHA10
EPH receptor A10
chr1_-_242612726 0.24 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr1_+_25071848 0.24 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr22_+_31277661 0.24 ENST00000454145.1
ENST00000453621.1
ENST00000431368.1
ENST00000535268.1
OSBP2
oxysterol binding protein 2
chr14_-_104028595 0.24 ENST00000337322.4
ENST00000445922.2
BAG5
BCL2-associated athanogene 5
chr19_+_32836499 0.23 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chr14_-_104029013 0.23 ENST00000299204.4
ENST00000557666.1
BAG5
BCL2-associated athanogene 5
chr9_+_117350009 0.23 ENST00000374050.3
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr2_-_179315490 0.22 ENST00000487082.1
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr5_-_145483932 0.22 ENST00000311450.4
PLAC8L1
PLAC8-like 1
chr15_+_44084040 0.22 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr11_+_122709200 0.22 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr6_-_89673280 0.22 ENST00000369475.3
ENST00000369485.4
ENST00000538899.1
ENST00000265607.6
RNGTT
RNA guanylyltransferase and 5'-phosphatase
chr1_+_41204506 0.21 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
NFYC
nuclear transcription factor Y, gamma
chr2_-_179315453 0.21 ENST00000432031.2
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr20_+_32250079 0.21 ENST00000375222.3
C20orf144
chromosome 20 open reading frame 144
chr19_-_5838768 0.21 ENST00000527106.1
ENST00000531199.1
ENST00000529165.1
FUT6
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr17_+_48046538 0.21 ENST00000240306.3
DLX4
distal-less homeobox 4
chr10_+_81065975 0.21 ENST00000446377.2
ZMIZ1
zinc finger, MIZ-type containing 1
chr12_-_111926342 0.20 ENST00000389154.3
ATXN2
ataxin 2
chr12_-_88535747 0.20 ENST00000309041.7
CEP290
centrosomal protein 290kDa
chr8_+_110552831 0.20 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr3_-_195270162 0.20 ENST00000438848.1
ENST00000328432.3
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr2_+_230787213 0.20 ENST00000409992.1
FBXO36
F-box protein 36
chr15_-_83315874 0.19 ENST00000569257.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr18_+_268148 0.19 ENST00000581677.1
RP11-705O1.8
RP11-705O1.8
chr16_-_74734742 0.19 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr18_+_19668021 0.19 ENST00000579830.1
RP11-595B24.2
Uncharacterized protein
chr3_+_12330560 0.19 ENST00000397026.2
PPARG
peroxisome proliferator-activated receptor gamma
chr2_-_230786619 0.19 ENST00000389045.3
ENST00000409677.1
TRIP12
thyroid hormone receptor interactor 12
chr20_+_56884752 0.19 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr2_-_55459485 0.19 ENST00000451916.1
CLHC1
clathrin heavy chain linker domain containing 1
chr17_-_58499766 0.19 ENST00000588898.1
USP32
ubiquitin specific peptidase 32
chr2_-_179315786 0.19 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr19_+_6739662 0.18 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10
thyroid hormone receptor interactor 10
chr6_-_150039249 0.18 ENST00000543571.1
LATS1
large tumor suppressor kinase 1
chr17_+_27369918 0.18 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr17_-_41132088 0.18 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr14_-_103523745 0.18 ENST00000361246.2
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr12_+_123874589 0.18 ENST00000437502.1
SETD8
SET domain containing (lysine methyltransferase) 8
chr2_-_55459294 0.18 ENST00000407122.1
ENST00000406437.2
CLHC1
clathrin heavy chain linker domain containing 1
chr6_-_150039170 0.18 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr9_-_114245938 0.18 ENST00000602447.1
KIAA0368
KIAA0368
chr1_+_179851893 0.18 ENST00000531630.2
TOR1AIP1
torsin A interacting protein 1
chr13_+_41635617 0.17 ENST00000542082.1
WBP4
WW domain binding protein 4
chr1_+_152881014 0.17 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr7_+_73868439 0.17 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr13_-_76111945 0.17 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr19_-_58485895 0.17 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr17_-_18161870 0.17 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
FLII
flightless I homolog (Drosophila)
chr8_+_97597148 0.17 ENST00000521590.1
SDC2
syndecan 2
chr22_+_23243156 0.17 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr14_+_58765305 0.17 ENST00000445108.1
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr3_-_98241760 0.16 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr12_+_41221975 0.16 ENST00000552913.1
CNTN1
contactin 1
chr1_+_17634689 0.16 ENST00000375453.1
ENST00000375448.4
PADI4
peptidyl arginine deiminase, type IV
chr17_-_10633535 0.16 ENST00000341871.3
TMEM220
transmembrane protein 220
chr1_+_32827759 0.16 ENST00000373534.3
TSSK3
testis-specific serine kinase 3
chr7_+_128431444 0.16 ENST00000459946.1
ENST00000378685.4
ENST00000464832.1
ENST00000472049.1
ENST00000488925.1
CCDC136
coiled-coil domain containing 136
chr14_-_21492251 0.16 ENST00000554398.1
NDRG2
NDRG family member 2
chr12_+_119616447 0.16 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr11_-_27722021 0.16 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
BDNF
brain-derived neurotrophic factor
chr1_+_178482212 0.16 ENST00000319416.2
ENST00000258298.2
ENST00000367643.3
ENST00000367642.3
TEX35
testis expressed 35
chr12_+_52668394 0.15 ENST00000423955.2
KRT86
keratin 86
chr1_-_91487770 0.15 ENST00000337393.5
ZNF644
zinc finger protein 644
chr12_-_51566562 0.15 ENST00000548108.1
TFCP2
transcription factor CP2
chr14_+_58765103 0.15 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr16_-_58328884 0.15 ENST00000569079.1
PRSS54
protease, serine, 54
chr18_+_61144160 0.15 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr8_-_144413981 0.15 ENST00000522041.1
TOP1MT
topoisomerase (DNA) I, mitochondrial
chr7_+_94536514 0.15 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr17_-_7082861 0.15 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr2_+_55459808 0.15 ENST00000404735.1
RPS27A
ribosomal protein S27a
chr22_-_29137771 0.15 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr9_-_139305051 0.15 ENST00000371725.3
ENST00000298537.7
SDCCAG3
serologically defined colon cancer antigen 3
chr1_-_17380630 0.15 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr12_-_122907091 0.15 ENST00000358808.2
ENST00000361654.4
ENST00000539080.1
ENST00000537178.1
CLIP1
CAP-GLY domain containing linker protein 1
chr12_-_102513843 0.15 ENST00000551744.2
ENST00000552283.1
NUP37
nucleoporin 37kDa
chr2_+_179316163 0.15 ENST00000409117.3
DFNB59
deafness, autosomal recessive 59
chr12_+_102513950 0.15 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chr2_-_55459437 0.14 ENST00000401408.1
CLHC1
clathrin heavy chain linker domain containing 1
chr15_-_93965805 0.14 ENST00000556708.1
RP11-164C12.2
RP11-164C12.2
chr4_+_26321284 0.14 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr16_-_28192360 0.14 ENST00000570033.1
XPO6
exportin 6
chr3_-_197024965 0.14 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr3_-_15374659 0.14 ENST00000426925.1
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr3_+_9404526 0.14 ENST00000452837.2
ENST00000417036.1
ENST00000419437.1
ENST00000345094.3
ENST00000515662.2
THUMPD3
THUMP domain containing 3
chr8_-_42698433 0.14 ENST00000345117.2
ENST00000254250.3
THAP1
THAP domain containing, apoptosis associated protein 1
chr9_+_131452239 0.14 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr15_-_31393910 0.14 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr14_-_101351184 0.14 ENST00000534062.1
RTL1
retrotransposon-like 1
chr3_+_179322573 0.14 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr1_-_91487806 0.14 ENST00000361321.5
ZNF644
zinc finger protein 644
chr17_-_3595042 0.14 ENST00000552723.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr9_+_36572851 0.13 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr7_+_112090483 0.13 ENST00000403825.3
ENST00000429071.1
IFRD1
interferon-related developmental regulator 1
chr8_-_42698292 0.13 ENST00000529779.1
THAP1
THAP domain containing, apoptosis associated protein 1
chr14_-_21492113 0.13 ENST00000554094.1
NDRG2
NDRG family member 2
chr19_+_45281118 0.13 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr17_-_58469687 0.13 ENST00000590133.1
USP32
ubiquitin specific peptidase 32
chr5_+_145583156 0.13 ENST00000265271.5
RBM27
RNA binding motif protein 27
chr2_+_219745020 0.13 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr7_+_120969045 0.13 ENST00000222462.2
WNT16
wingless-type MMTV integration site family, member 16
chr7_+_76751926 0.13 ENST00000285871.4
ENST00000431197.1
CCDC146
coiled-coil domain containing 146
chrX_-_13835461 0.13 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr11_-_17565854 0.13 ENST00000005226.7
USH1C
Usher syndrome 1C (autosomal recessive, severe)
chr7_+_5085452 0.13 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RBAK
RBAK-RBAKDN
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr14_-_102552659 0.13 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr5_+_179125907 0.13 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
CANX
calnexin
chr3_-_127872625 0.13 ENST00000464873.1
RUVBL1
RuvB-like AAA ATPase 1
chrX_+_135230712 0.13 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr1_-_85156216 0.12 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr1_-_85040090 0.12 ENST00000370630.5
CTBS
chitobiase, di-N-acetyl-
chr5_+_170288856 0.12 ENST00000523189.1
RANBP17
RAN binding protein 17
chr1_-_175162048 0.12 ENST00000444639.1
KIAA0040
KIAA0040
chr15_+_48413169 0.12 ENST00000341459.3
ENST00000482911.2
SLC24A5
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr18_+_61143994 0.12 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr3_+_141105235 0.12 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr4_+_177241094 0.12 ENST00000503362.1
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr12_+_120875910 0.12 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr1_+_82165350 0.12 ENST00000359929.3
LPHN2
latrophilin 2
chr6_+_64346386 0.12 ENST00000509330.1
PHF3
PHD finger protein 3
chr17_+_43922241 0.12 ENST00000329196.5
SPPL2C
signal peptide peptidase like 2C
chr12_+_27849378 0.12 ENST00000310791.2
REP15
RAB15 effector protein
chr13_+_113030658 0.11 ENST00000414180.1
ENST00000443541.1
SPACA7
sperm acrosome associated 7
chr7_-_95064264 0.11 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2
paraoxonase 2
chr11_+_111896090 0.11 ENST00000393051.1
DLAT
dihydrolipoamide S-acetyltransferase
chr7_+_94536898 0.11 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr10_+_95372289 0.11 ENST00000371447.3
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr3_-_197025447 0.11 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
DLG1
discs, large homolog 1 (Drosophila)
chr16_-_74734672 0.11 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr2_-_75745823 0.11 ENST00000452003.1
EVA1A
eva-1 homolog A (C. elegans)
chr2_-_33824382 0.11 ENST00000238823.8
FAM98A
family with sequence similarity 98, member A
chr1_-_160231451 0.11 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr12_+_95611569 0.11 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr14_+_71788096 0.11 ENST00000557151.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr1_-_35325400 0.11 ENST00000521580.2
SMIM12
small integral membrane protein 12
chr1_+_150954493 0.11 ENST00000368947.4
ANXA9
annexin A9
chr1_+_70876891 0.11 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr8_+_145086574 0.11 ENST00000377470.3
ENST00000447830.2
SPATC1
spermatogenesis and centriole associated 1
chr6_-_31782813 0.11 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr1_-_205719295 0.11 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr15_+_45422131 0.10 ENST00000321429.4
DUOX1
dual oxidase 1
chr12_+_7072354 0.10 ENST00000537269.1
U47924.27
U47924.27
chr1_+_109255279 0.10 ENST00000370017.3
FNDC7
fibronectin type III domain containing 7
chr11_+_33563821 0.10 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr1_-_6453426 0.10 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chr13_+_76123883 0.10 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr14_-_82000140 0.10 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr3_+_87276407 0.10 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
CHMP2B
charged multivesicular body protein 2B
chrX_+_23928500 0.10 ENST00000435707.1
CXorf58
chromosome X open reading frame 58

Network of associatons between targets according to the STRING database.

First level regulatory network of THRA_RXRB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0060629 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.2 0.7 GO:0060032 notochord regression(GO:0060032)
0.1 0.3 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.5 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.4 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.3 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:2000230 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.5 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.6 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.2 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.2 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.8 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.2 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0038194 thyroid-stimulating hormone signaling pathway(GO:0038194)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0097198 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 trimethylation(GO:0097198)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.3 GO:0044146 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.2 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0 0.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.0 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.2 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.0 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:1903276 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.2 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.0 GO:1900200 regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) negative regulation of somatic stem cell population maintenance(GO:1904673)
0.0 0.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0032106 positive regulation of macroautophagy(GO:0016239) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.0 1.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.0 GO:0098844 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.8 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.2 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.6 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.0 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex