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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TCF7L1

Z-value: 0.50

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Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
TCF7L1
ENSG00000152284.4 transcription factor 7 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L1hg19_v2_chr2_+_85360499_85360598-0.316.9e-01Click!

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_102200948 0.46 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr2_+_233734994 0.44 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr19_+_51152702 0.43 ENST00000425202.1
C19orf81
chromosome 19 open reading frame 81
chr17_-_7297833 0.37 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr16_+_2820912 0.35 ENST00000570539.1
SRRM2
serine/arginine repetitive matrix 2
chr17_+_62223320 0.33 ENST00000580828.1
ENST00000582965.1
SNORA76
small nucleolar RNA, H/ACA box 76
chr7_-_105926058 0.33 ENST00000417537.1
NAMPT
nicotinamide phosphoribosyltransferase
chr12_-_108154705 0.33 ENST00000547188.1
PRDM4
PR domain containing 4
chr1_+_16085263 0.31 ENST00000483633.2
ENST00000502739.1
ENST00000431771.2
FBLIM1
filamin binding LIM protein 1
chr17_+_79679299 0.31 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr14_-_23791484 0.30 ENST00000594872.1
AL049829.1
Uncharacterized protein
chr15_-_90294523 0.29 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr14_-_20922960 0.29 ENST00000553640.1
ENST00000488532.2
OSGEP
O-sialoglycoprotein endopeptidase
chr17_+_72428266 0.28 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_-_32145861 0.25 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr19_-_59030921 0.25 ENST00000354590.3
ENST00000596739.1
ZBTB45
zinc finger and BTB domain containing 45
chr11_+_65339820 0.24 ENST00000316409.2
ENST00000449319.2
ENST00000530349.1
FAM89B
family with sequence similarity 89, member B
chr12_-_49453557 0.23 ENST00000547610.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr11_-_65381643 0.22 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr17_+_72428218 0.22 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr19_-_59031118 0.22 ENST00000600990.1
ZBTB45
zinc finger and BTB domain containing 45
chr13_-_30160925 0.21 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_-_175964366 0.21 ENST00000274811.4
RNF44
ring finger protein 44
chr15_+_81293254 0.20 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr19_-_7990991 0.19 ENST00000318978.4
CTXN1
cortexin 1
chr5_+_175288631 0.19 ENST00000509837.1
CPLX2
complexin 2
chr1_-_1334685 0.18 ENST00000400809.3
ENST00000408918.4
CCNL2
cyclin L2
chr9_-_27005686 0.17 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr8_+_17104401 0.17 ENST00000324815.3
ENST00000518038.1
VPS37A
vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr12_-_130529501 0.17 ENST00000561864.1
ENST00000567788.1
RP11-474D1.4
RP11-474D1.3
RP11-474D1.4
RP11-474D1.3
chr18_+_3450161 0.17 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr1_+_16085244 0.16 ENST00000400773.1
FBLIM1
filamin binding LIM protein 1
chr14_-_23451845 0.16 ENST00000262713.2
AJUBA
ajuba LIM protein
chr11_-_117747327 0.16 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr2_-_97534312 0.16 ENST00000442264.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr7_+_150076406 0.16 ENST00000329630.5
ZNF775
zinc finger protein 775
chr14_-_23451467 0.15 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
AJUBA
RP11-298I3.5
ajuba LIM protein
chr12_+_28605426 0.15 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr17_-_7297519 0.15 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr16_-_73082274 0.15 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr3_-_148939598 0.15 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr16_-_4852915 0.15 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr1_-_43424500 0.15 ENST00000415851.2
ENST00000426263.3
ENST00000372500.3
SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr19_+_41257084 0.14 ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr16_+_30406423 0.14 ENST00000524644.1
ZNF48
zinc finger protein 48
chr6_-_33548006 0.14 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr14_-_65409502 0.14 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr11_+_65999265 0.14 ENST00000528935.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr8_-_145047688 0.14 ENST00000356346.3
PLEC
plectin
chr17_-_46035187 0.13 ENST00000300557.2
PRR15L
proline rich 15-like
chrX_+_54835493 0.13 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr10_-_104192405 0.13 ENST00000369937.4
CUEDC2
CUE domain containing 2
chr12_+_1738363 0.12 ENST00000397196.2
WNT5B
wingless-type MMTV integration site family, member 5B
chr19_-_3061397 0.12 ENST00000586839.1
AES
amino-terminal enhancer of split
chr9_+_139221880 0.12 ENST00000392945.3
ENST00000440944.1
GPSM1
G-protein signaling modulator 1
chr22_-_31688431 0.12 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr11_-_62474803 0.12 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_+_53491220 0.11 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr14_+_105941118 0.11 ENST00000550577.1
ENST00000538259.2
CRIP2
cysteine-rich protein 2
chr12_-_49449107 0.11 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D
chr7_+_80275953 0.11 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr18_-_56985776 0.11 ENST00000587244.1
CPLX4
complexin 4
chr1_-_32801825 0.11 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr10_+_54074033 0.11 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr15_+_90744745 0.11 ENST00000558051.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr20_+_36149602 0.11 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr11_-_46615498 0.10 ENST00000533727.1
ENST00000534300.1
ENST00000528950.1
ENST00000526606.1
AMBRA1
autophagy/beclin-1 regulator 1
chr20_+_55966444 0.10 ENST00000356208.5
ENST00000440234.2
RBM38
RNA binding motif protein 38
chr19_-_40791302 0.10 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr10_-_101380121 0.10 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr6_-_33547975 0.10 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr19_-_11450249 0.10 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr1_-_219615984 0.10 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr12_-_49582978 0.09 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr19_+_51153045 0.09 ENST00000458538.1
C19orf81
chromosome 19 open reading frame 81
chr12_+_54694979 0.09 ENST00000552848.1
COPZ1
coatomer protein complex, subunit zeta 1
chr6_-_107436473 0.09 ENST00000369042.1
BEND3
BEN domain containing 3
chr2_+_47168630 0.09 ENST00000263737.6
TTC7A
tetratricopeptide repeat domain 7A
chr19_+_1249869 0.09 ENST00000591446.2
MIDN
midnolin
chr9_+_109685630 0.09 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr17_+_80416050 0.09 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
NARF
nuclear prelamin A recognition factor
chr1_+_36348790 0.09 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr5_-_58335281 0.09 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_64995399 0.09 ENST00000559753.1
ENST00000560258.2
ENST00000559912.2
ENST00000326005.6
OAZ2
ornithine decarboxylase antizyme 2
chr12_-_49582837 0.08 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
TUBA1A
tubulin, alpha 1a
chr1_-_6479963 0.08 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
HES2
hes family bHLH transcription factor 2
chr17_-_39093672 0.08 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr3_+_152879985 0.08 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr20_+_44509857 0.08 ENST00000372523.1
ENST00000372520.1
ZSWIM1
zinc finger, SWIM-type containing 1
chr2_+_196440692 0.08 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr22_-_31688381 0.07 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr10_+_71561630 0.07 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr4_-_140477910 0.07 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr1_-_200992827 0.07 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr1_+_8378140 0.07 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr7_+_73245193 0.07 ENST00000340958.2
CLDN4
claudin 4
chr2_+_47168313 0.07 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr8_-_11660077 0.07 ENST00000533405.1
RP11-297N6.4
Uncharacterized protein
chrX_-_128788914 0.07 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr4_-_120243545 0.07 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr7_+_73703728 0.07 ENST00000361545.5
ENST00000223398.6
CLIP2
CAP-GLY domain containing linker protein 2
chr1_+_87794150 0.07 ENST00000370544.5
LMO4
LIM domain only 4
chr16_+_57673348 0.06 ENST00000567915.1
ENST00000564103.1
ENST00000562467.1
GPR56
G protein-coupled receptor 56
chr5_+_55354822 0.06 ENST00000511861.1
CTD-2227I18.1
CTD-2227I18.1
chr7_+_128828713 0.06 ENST00000249373.3
SMO
smoothened, frizzled family receptor
chr16_+_30406721 0.06 ENST00000320159.2
ZNF48
zinc finger protein 48
chr2_-_208031943 0.06 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chrX_-_153599578 0.06 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr12_+_9066472 0.05 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr15_+_65134088 0.05 ENST00000323544.4
ENST00000437723.1
PLEKHO2
AC069368.3
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr12_+_109915179 0.05 ENST00000434735.2
UBE3B
ubiquitin protein ligase E3B
chr20_-_656437 0.05 ENST00000488788.2
RP5-850E9.3
Uncharacterized protein
chr15_+_75074410 0.05 ENST00000439220.2
CSK
c-src tyrosine kinase
chr1_+_59762642 0.05 ENST00000371218.4
ENST00000303721.7
FGGY
FGGY carbohydrate kinase domain containing
chr17_+_80416482 0.05 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF
nuclear prelamin A recognition factor
chr1_-_231005310 0.05 ENST00000470540.1
C1orf198
chromosome 1 open reading frame 198
chr18_+_3449821 0.05 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr7_-_106301405 0.05 ENST00000523505.1
CCDC71L
coiled-coil domain containing 71-like
chr11_-_87908600 0.05 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chrX_+_152760397 0.05 ENST00000331595.4
ENST00000431891.1
BGN
biglycan
chr15_+_80696666 0.05 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr7_+_139528952 0.05 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr5_-_157002775 0.05 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr5_-_138725560 0.04 ENST00000412103.2
ENST00000457570.2
MZB1
marginal zone B and B1 cell-specific protein
chr17_+_42923686 0.04 ENST00000591513.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr2_+_27071292 0.04 ENST00000431402.1
ENST00000434719.1
DPYSL5
dihydropyrimidinase-like 5
chr11_-_75921780 0.04 ENST00000529461.1
WNT11
wingless-type MMTV integration site family, member 11
chr12_-_58146128 0.04 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4
cyclin-dependent kinase 4
chr2_+_179184955 0.04 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr19_+_41256764 0.04 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr10_+_22605304 0.04 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr8_-_33424636 0.04 ENST00000256257.1
RNF122
ring finger protein 122
chr10_+_114710425 0.04 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr19_+_8274204 0.04 ENST00000561053.1
ENST00000251363.5
ENST00000559450.1
ENST00000559336.1
CERS4
ceramide synthase 4
chr1_-_109935819 0.04 ENST00000538502.1
SORT1
sortilin 1
chr13_+_39612485 0.04 ENST00000379599.2
NHLRC3
NHL repeat containing 3
chr22_+_41347363 0.04 ENST00000216225.8
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr17_+_80416609 0.04 ENST00000577410.1
NARF
nuclear prelamin A recognition factor
chr12_+_56324933 0.04 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr15_+_75074915 0.04 ENST00000567123.1
ENST00000569462.1
CSK
c-src tyrosine kinase
chr8_-_124553437 0.03 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chrX_-_110655391 0.03 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chr6_+_134274354 0.03 ENST00000367869.1
TBPL1
TBP-like 1
chr10_+_11206925 0.03 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr17_+_35851570 0.03 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr6_+_143929307 0.03 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr2_-_165697717 0.03 ENST00000439313.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr3_-_149375783 0.03 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr15_+_43885799 0.03 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr17_-_61819229 0.03 ENST00000447001.3
ENST00000392950.4
STRADA
STE20-related kinase adaptor alpha
chr7_-_27219849 0.03 ENST00000396344.4
HOXA10
homeobox A10
chr13_+_24144796 0.03 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr2_-_166060552 0.03 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr6_+_35704855 0.03 ENST00000288065.2
ENST00000373866.3
ARMC12
armadillo repeat containing 12
chr19_-_40791211 0.03 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr17_+_70026795 0.03 ENST00000472655.2
ENST00000538810.1
RP11-84E24.3
long intergenic non-protein coding RNA 1152
chr1_+_223101757 0.03 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr8_-_95220775 0.03 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr13_+_24144509 0.03 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chrX_+_106163626 0.03 ENST00000336803.1
CLDN2
claudin 2
chr13_+_30002741 0.03 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr19_+_8274185 0.03 ENST00000558268.1
ENST00000558331.1
CERS4
ceramide synthase 4
chr14_+_75746664 0.03 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr6_+_12008986 0.03 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr4_-_69215699 0.03 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr14_-_73493825 0.03 ENST00000318876.5
ENST00000556143.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr1_-_20126365 0.03 ENST00000294543.6
ENST00000375122.2
TMCO4
transmembrane and coiled-coil domains 4
chr12_-_49582593 0.03 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr8_+_21777243 0.03 ENST00000521303.1
XPO7
exportin 7
chr6_+_119215308 0.03 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr4_-_139163491 0.02 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_+_180199393 0.02 ENST00000263726.2
LHX4
LIM homeobox 4
chr4_+_79567362 0.02 ENST00000512322.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr1_+_154244987 0.02 ENST00000328703.7
ENST00000457918.2
ENST00000483970.2
ENST00000435087.1
ENST00000532105.1
HAX1
HCLS1 associated protein X-1
chrX_-_110655306 0.02 ENST00000371993.2
DCX
doublecortin
chr9_+_124088860 0.02 ENST00000373806.1
GSN
gelsolin
chr2_-_166060571 0.02 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr10_+_71561704 0.02 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr1_-_94079648 0.02 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr9_-_74525847 0.02 ENST00000377041.2
ABHD17B
abhydrolase domain containing 17B
chr11_+_69455855 0.02 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr10_+_71561649 0.02 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chrX_+_69488174 0.02 ENST00000480877.2
ENST00000307959.8
ARR3
arrestin 3, retinal (X-arrestin)
chr13_+_30002846 0.02 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr12_+_80603233 0.02 ENST00000547103.1
ENST00000458043.2
OTOGL
otogelin-like
chr10_+_71562180 0.02 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr19_-_18717627 0.02 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr11_+_77184416 0.02 ENST00000598970.1
DKFZP434E1119
DKFZP434E1119
chr8_-_128231299 0.02 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr10_+_22605374 0.02 ENST00000448361.1
COMMD3
COMM domain containing 3
chr11_+_36317830 0.02 ENST00000530639.1
PRR5L
proline rich 5 like
chr8_-_29939933 0.02 ENST00000522794.1
TMEM66
transmembrane protein 66
chr7_-_27213893 0.02 ENST00000283921.4
HOXA10
homeobox A10
chr6_+_108881012 0.02 ENST00000343882.6
FOXO3
forkhead box O3
chr14_+_39644425 0.01 ENST00000556530.1
PNN
pinin, desmosome associated protein
chr2_+_48796120 0.01 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr3_-_47823298 0.01 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr12_-_109915098 0.01 ENST00000542858.1
ENST00000542262.1
ENST00000424763.2
KCTD10
potassium channel tetramerization domain containing 10
chr5_+_102201430 0.01 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr2_+_191273052 0.01 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6
major facilitator superfamily domain containing 6

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0090381 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.1 0.3 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.2 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.3 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.4 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions