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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TCF7

Z-value: 1.44

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Transcription factors associated with TCF7

Gene Symbol Gene ID Gene Info
TCF7
ENSG00000081059.15 transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7hg19_v2_chr5_+_133450365_133450444-0.973.1e-02Click!

Activity profile of TCF7 motif

Sorted Z-values of TCF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_57229155 0.55 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chrX_-_148676974 0.53 ENST00000524178.1
HSFX2
heat shock transcription factor family, X linked 2
chr9_-_21077939 0.52 ENST00000380232.2
IFNB1
interferon, beta 1, fibroblast
chr1_+_200993071 0.49 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chrX_-_55020511 0.49 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr15_+_36871983 0.49 ENST00000437989.2
ENST00000569302.1
C15orf41
chromosome 15 open reading frame 41
chr5_+_136070614 0.48 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chrX_+_148855726 0.45 ENST00000370416.4
HSFX1
heat shock transcription factor family, X linked 1
chr12_+_8849773 0.45 ENST00000541044.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr12_-_49582593 0.45 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr12_+_21654714 0.44 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr15_+_74466012 0.44 ENST00000249842.3
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr2_-_99871570 0.43 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr14_+_32414059 0.42 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chr3_+_159570722 0.41 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr9_-_130639997 0.41 ENST00000373176.1
AK1
adenylate kinase 1
chr19_-_14992264 0.41 ENST00000327462.2
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr17_+_30813576 0.40 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr16_-_81110683 0.39 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
C16orf46
chromosome 16 open reading frame 46
chr9_-_21228221 0.39 ENST00000413767.2
IFNA17
interferon, alpha 17
chr10_-_14613968 0.38 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr15_-_52043722 0.38 ENST00000454181.2
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr7_+_89975979 0.37 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTPBP10
GTP-binding protein 10 (putative)
chr2_-_86564740 0.37 ENST00000540790.1
ENST00000428491.1
REEP1
receptor accessory protein 1
chr12_+_6309963 0.37 ENST00000382515.2
CD9
CD9 molecule
chr6_-_29527702 0.37 ENST00000377050.4
UBD
ubiquitin D
chr1_-_11107280 0.36 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr12_-_49581152 0.36 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr15_+_63414760 0.36 ENST00000557972.1
LACTB
lactamase, beta
chr5_+_34757309 0.34 ENST00000397449.1
RAI14
retinoic acid induced 14
chr3_-_167813132 0.33 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr17_-_56065540 0.32 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr10_+_52152766 0.32 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr11_-_3013482 0.32 ENST00000529361.1
ENST00000528968.1
ENST00000534372.1
ENST00000531291.1
ENST00000526842.1
NAP1L4
nucleosome assembly protein 1-like 4
chr2_-_151344172 0.31 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr17_+_31254892 0.31 ENST00000394642.3
ENST00000579849.1
TMEM98
transmembrane protein 98
chr1_+_28527070 0.30 ENST00000596102.1
AL353354.2
AL353354.2
chr1_-_211752073 0.30 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr16_-_46864955 0.30 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr17_-_63556414 0.29 ENST00000585045.1
AXIN2
axin 2
chr8_-_134511587 0.29 ENST00000523855.1
ENST00000523854.1
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr11_-_76155618 0.29 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr14_-_36645674 0.28 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr6_-_27440460 0.28 ENST00000377419.1
ZNF184
zinc finger protein 184
chr11_+_65851443 0.28 ENST00000533756.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr4_+_109541772 0.28 ENST00000506397.1
ENST00000394668.2
RPL34
ribosomal protein L34
chr6_+_160183492 0.28 ENST00000541436.1
ACAT2
acetyl-CoA acetyltransferase 2
chr6_+_155538093 0.28 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr15_-_35280426 0.27 ENST00000559564.1
ENST00000356321.4
ZNF770
zinc finger protein 770
chr7_+_112120908 0.27 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
LSMEM1
leucine-rich single-pass membrane protein 1
chr4_+_109541740 0.26 ENST00000394665.1
RPL34
ribosomal protein L34
chr2_+_70056762 0.26 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr19_+_13135439 0.26 ENST00000586873.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_59762642 0.26 ENST00000371218.4
ENST00000303721.7
FGGY
FGGY carbohydrate kinase domain containing
chr6_-_27440837 0.26 ENST00000211936.6
ZNF184
zinc finger protein 184
chr11_+_113848216 0.26 ENST00000299961.5
HTR3A
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
chr7_-_80548667 0.26 ENST00000265361.3
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr3_-_197024394 0.26 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr6_+_155537771 0.26 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr22_+_19950060 0.26 ENST00000449653.1
COMT
catechol-O-methyltransferase
chr6_+_138188551 0.26 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_-_55690758 0.25 ENST00000590851.1
SYT5
synaptotagmin V
chr11_-_125365435 0.25 ENST00000524435.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr12_-_58329819 0.25 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr4_-_23735183 0.25 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chrX_+_100646190 0.25 ENST00000471855.1
RPL36A
ribosomal protein L36a
chr19_+_12273866 0.24 ENST00000425827.1
ENST00000439995.1
ENST00000343979.4
ENST00000398616.2
ENST00000418338.1
ZNF136
zinc finger protein 136
chr4_+_95128748 0.24 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr17_-_37009882 0.24 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
RPL23
ribosomal protein L23
chr7_+_123469037 0.23 ENST00000489978.1
HYAL4
hyaluronoglucosaminidase 4
chr2_+_10183651 0.23 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr4_+_71859156 0.23 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr12_+_69080734 0.23 ENST00000378905.2
NUP107
nucleoporin 107kDa
chr19_+_57791806 0.23 ENST00000360338.3
ZNF460
zinc finger protein 460
chr4_-_5891918 0.23 ENST00000512574.1
CRMP1
collapsin response mediator protein 1
chr17_-_63557309 0.23 ENST00000580513.1
AXIN2
axin 2
chr7_-_148725733 0.22 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr14_-_85996332 0.22 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr11_-_3013497 0.22 ENST00000448187.1
ENST00000532325.2
ENST00000399614.2
NAP1L4
nucleosome assembly protein 1-like 4
chr11_+_120039685 0.21 ENST00000530303.1
ENST00000319763.1
AP000679.2
Uncharacterized protein
chr13_+_30002846 0.21 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr4_-_7069760 0.21 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr6_+_13925098 0.21 ENST00000488300.1
ENST00000544682.1
ENST00000420478.2
RNF182
ring finger protein 182
chr10_+_104629199 0.21 ENST00000369880.3
AS3MT
arsenic (+3 oxidation state) methyltransferase
chr10_+_96698406 0.21 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr6_-_112408661 0.21 ENST00000368662.5
TUBE1
tubulin, epsilon 1
chr10_+_70847852 0.21 ENST00000242465.3
SRGN
serglycin
chr9_+_91003271 0.21 ENST00000375859.3
ENST00000541629.1
SPIN1
spindlin 1
chr11_-_6677018 0.20 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr5_+_32531893 0.20 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)
chr3_+_14989186 0.20 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr20_-_39317868 0.20 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr19_+_21579908 0.20 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr9_-_35071960 0.19 ENST00000417448.1
VCP
valosin containing protein
chr2_-_27592867 0.19 ENST00000451130.2
EIF2B4
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr10_-_14614095 0.19 ENST00000482277.1
ENST00000378462.1
FAM107B
family with sequence similarity 107, member B
chr17_+_80416609 0.19 ENST00000577410.1
NARF
nuclear prelamin A recognition factor
chr6_+_64282447 0.19 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr12_+_69979446 0.19 ENST00000543146.2
CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr4_-_103266219 0.19 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr6_+_13925318 0.19 ENST00000423553.2
ENST00000537388.1
RNF182
ring finger protein 182
chr3_-_167813672 0.18 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr5_+_150040403 0.18 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr10_-_14614311 0.18 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr11_-_76155700 0.18 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr11_-_125366018 0.18 ENST00000527534.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr19_+_11909329 0.18 ENST00000323169.5
ENST00000450087.1
ZNF491
zinc finger protein 491
chr15_-_44487408 0.18 ENST00000402883.1
ENST00000417257.1
FRMD5
FERM domain containing 5
chr2_+_234621551 0.18 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr2_-_36825281 0.18 ENST00000405912.3
ENST00000379245.4
FEZ2
fasciculation and elongation protein zeta 2 (zygin II)
chr17_-_56065484 0.18 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr13_+_36920569 0.18 ENST00000379848.2
SPG20OS
SPG20 opposite strand
chr19_+_57791419 0.17 ENST00000537645.1
ZNF460
zinc finger protein 460
chr13_+_102104980 0.17 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr15_-_89764929 0.17 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr17_+_41150479 0.17 ENST00000589913.1
RPL27
ribosomal protein L27
chr7_-_91794590 0.17 ENST00000430130.2
ENST00000454089.2
LRRD1
leucine-rich repeats and death domain containing 1
chr12_+_58937907 0.17 ENST00000546977.1
RP11-362K2.2
Protein LOC100506869
chr1_+_182808474 0.17 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chrX_+_12993336 0.16 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr16_-_46865047 0.16 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr12_-_69080590 0.16 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2
RP11-637A17.2
chr1_+_11072696 0.16 ENST00000240185.3
ENST00000476201.1
TARDBP
TAR DNA binding protein
chrX_-_16881144 0.16 ENST00000416035.1
RBBP7
retinoblastoma binding protein 7
chr1_+_68150744 0.16 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr8_+_73921085 0.16 ENST00000276603.5
ENST00000276602.6
ENST00000518874.1
TERF1
telomeric repeat binding factor (NIMA-interacting) 1
chr4_+_109541722 0.16 ENST00000394667.3
ENST00000502534.1
RPL34
ribosomal protein L34
chr11_+_45943169 0.15 ENST00000529052.1
ENST00000531526.1
GYLTL1B
glycosyltransferase-like 1B
chr2_-_27593180 0.15 ENST00000493344.2
ENST00000445933.2
EIF2B4
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr2_+_69240302 0.15 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr7_+_107384142 0.15 ENST00000440859.3
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr1_-_53793584 0.15 ENST00000354412.3
ENST00000347547.2
ENST00000306052.6
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chrX_+_100663243 0.15 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr3_-_47622282 0.15 ENST00000383738.2
ENST00000264723.4
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr7_+_73868439 0.15 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr15_-_98646940 0.15 ENST00000560195.1
CTD-2544M6.2
CTD-2544M6.2
chr2_+_189157536 0.15 ENST00000409580.1
ENST00000409637.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr21_+_17553910 0.15 ENST00000428669.2
LINC00478
long intergenic non-protein coding RNA 478
chr1_-_6546001 0.15 ENST00000400913.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr6_+_64281906 0.15 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_-_220608023 0.15 ENST00000416839.2
AC096644.1
Uncharacterized protein
chr2_-_136288740 0.15 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr7_-_19748640 0.14 ENST00000222567.5
TWISTNB
TWIST neighbor
chr13_+_30002741 0.14 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr12_+_104359576 0.14 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr11_-_122930121 0.14 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr22_-_26908343 0.14 ENST00000407431.1
ENST00000455080.1
ENST00000418876.1
ENST00000440258.1
ENST00000407148.1
ENST00000420242.1
ENST00000405938.1
ENST00000407690.1
TFIP11
tuftelin interacting protein 11
chr12_-_133464118 0.14 ENST00000540963.1
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr3_+_169490606 0.14 ENST00000349841.5
MYNN
myoneurin
chr14_-_35344093 0.14 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr11_+_46740730 0.14 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr8_+_27629459 0.14 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr17_-_79818354 0.13 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr12_-_8043736 0.13 ENST00000539924.1
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr12_+_104359614 0.13 ENST00000266775.9
ENST00000544861.1
TDG
thymine-DNA glycosylase
chr2_-_158182105 0.13 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr4_-_140477928 0.13 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr17_+_80416482 0.13 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF
nuclear prelamin A recognition factor
chr10_+_99627889 0.13 ENST00000596005.1
GOLGA7B
Golgin subfamily A member 7B; cDNA FLJ43465 fis, clone OCBBF2036476
chr14_+_32798547 0.13 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr17_-_20946710 0.13 ENST00000584538.1
USP22
ubiquitin specific peptidase 22
chr1_+_145470504 0.13 ENST00000323397.4
ANKRD34A
ankyrin repeat domain 34A
chr18_-_5895954 0.13 ENST00000581347.2
TMEM200C
transmembrane protein 200C
chr11_-_85430204 0.13 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr7_+_111846643 0.13 ENST00000361822.3
ZNF277
zinc finger protein 277
chr1_-_75198940 0.13 ENST00000417775.1
CRYZ
crystallin, zeta (quinone reductase)
chr8_+_30244580 0.12 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr10_+_5090940 0.12 ENST00000602997.1
AKR1C3
aldo-keto reductase family 1, member C3
chr13_+_42846272 0.12 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr4_+_95129061 0.12 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr14_+_93118813 0.12 ENST00000556418.1
RIN3
Ras and Rab interactor 3
chr19_+_45281118 0.12 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chrX_+_146993449 0.12 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1
fragile X mental retardation 1
chr5_-_174871136 0.12 ENST00000393752.2
DRD1
dopamine receptor D1
chr19_+_41256764 0.12 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr20_+_5987890 0.12 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr8_-_124279627 0.12 ENST00000357082.4
ZHX1-C8ORF76
ZHX1-C8ORF76 readthrough
chr7_-_16840820 0.12 ENST00000450569.1
AGR2
anterior gradient 2
chr9_+_125703282 0.12 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr6_+_32146131 0.12 ENST00000375094.3
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr2_-_136594740 0.12 ENST00000264162.2
LCT
lactase
chr4_+_56815102 0.12 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr12_-_11150474 0.12 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr10_-_99393208 0.12 ENST00000307450.6
MORN4
MORN repeat containing 4
chr8_+_133879193 0.12 ENST00000377869.1
ENST00000220616.4
TG
thyroglobulin
chr2_+_46926326 0.11 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr1_-_75198681 0.11 ENST00000370872.3
ENST00000370871.3
ENST00000340866.5
ENST00000370870.1
CRYZ
crystallin, zeta (quinone reductase)
chr15_+_74218787 0.11 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr8_+_56792377 0.11 ENST00000520220.2
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_53793725 0.11 ENST00000371454.2
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr12_-_46385811 0.11 ENST00000419565.2
SCAF11
SR-related CTD-associated factor 11
chr3_+_118892411 0.11 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chr3_+_171561127 0.11 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr7_+_100663353 0.11 ENST00000306151.4
MUC17
mucin 17, cell surface associated
chr4_+_159593271 0.11 ENST00000512251.1
ENST00000511912.1
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr3_+_36421826 0.11 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr18_+_12407895 0.11 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1
slowmo homolog 1 (Drosophila)
chr15_+_36871806 0.11 ENST00000566621.1
ENST00000564586.1
C15orf41
chromosome 15 open reading frame 41
chr12_-_96390108 0.11 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr1_+_16010779 0.11 ENST00000375799.3
ENST00000375793.2
PLEKHM2
pleckstrin homology domain containing, family M (with RUN domain) member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.4 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.5 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.3 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.1 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.1 0.2 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1 0.5 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.2 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.2 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.1 0.2 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.2 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.2 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.3 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.4 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.4 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.1 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.4 GO:0030432 peristalsis(GO:0030432)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.1 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) regulation of melanosome transport(GO:1902908) positive regulation of melanosome transport(GO:1902910)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:1903899 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.1 GO:1903286 regulation of potassium ion import(GO:1903286)
0.0 0.0 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.0 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.0 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0045180 basal cortex(GO:0045180)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 0.5 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.4 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.4 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.2 GO:0031433 telethonin binding(GO:0031433)
0.1 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) triplex DNA binding(GO:0045142)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.3 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.3 GO:0070404 NADH binding(GO:0070404)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.1 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway