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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TCF21

Z-value: 1.07

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
TCF21
ENSG00000118526.6 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_1342102760.128.8e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_68845417 0.92 ENST00000542875.1
RP11-81H14.2
RP11-81H14.2
chr17_+_68165657 0.62 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr14_+_104710541 0.54 ENST00000419115.1
C14orf144
chromosome 14 open reading frame 144
chr11_-_10920838 0.51 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr11_+_117103441 0.46 ENST00000531287.1
ENST00000531452.1
RNF214
ring finger protein 214
chr8_-_71519889 0.44 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr2_+_38177575 0.44 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr15_+_83776137 0.42 ENST00000322019.9
TM6SF1
transmembrane 6 superfamily member 1
chr1_+_212738676 0.42 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr1_-_114429997 0.41 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr6_-_31648150 0.39 ENST00000375858.3
ENST00000383237.4
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr2_-_122494487 0.38 ENST00000451734.1
ENST00000285814.4
MKI67IP
nucleolar protein interacting with the FHA domain of MKI67
chr18_+_3247779 0.37 ENST00000578611.1
ENST00000583449.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_-_149889382 0.37 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chrX_+_15756382 0.37 ENST00000318636.3
CA5B
carbonic anhydrase VB, mitochondrial
chr3_-_156840776 0.36 ENST00000471357.1
LINC00880
long intergenic non-protein coding RNA 880
chr2_+_33701684 0.36 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_-_99837856 0.35 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr17_+_71228740 0.34 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr8_-_112248400 0.33 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chr15_+_75487984 0.32 ENST00000563905.1
C15orf39
chromosome 15 open reading frame 39
chr5_+_49962772 0.32 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr17_+_71229346 0.31 ENST00000535032.2
ENST00000582793.1
C17orf80
chromosome 17 open reading frame 80
chr2_-_55276320 0.31 ENST00000357376.3
RTN4
reticulon 4
chr12_+_16500599 0.30 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr17_+_71228793 0.30 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr7_+_99102573 0.29 ENST00000394170.2
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr14_-_53258180 0.28 ENST00000554230.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr6_-_74161977 0.28 ENST00000370318.1
ENST00000370315.3
MB21D1
Mab-21 domain containing 1
chr12_-_11002063 0.28 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr1_-_150669604 0.28 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr8_+_33342268 0.27 ENST00000360128.6
MAK16
MAK16 homolog (S. cerevisiae)
chr7_+_66205712 0.27 ENST00000451741.2
ENST00000442563.1
ENST00000450873.2
ENST00000284957.5
KCTD7
RABGEF1
potassium channel tetramerization domain containing 7
RAB guanine nucleotide exchange factor (GEF) 1
chr3_-_52869205 0.26 ENST00000446157.2
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr1_+_78354175 0.26 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
NEXN
nexilin (F actin binding protein)
chr22_-_22863466 0.26 ENST00000406426.1
ENST00000360412.2
ZNF280B
zinc finger protein 280B
chr22_+_38071615 0.26 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr17_-_7493390 0.25 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15
SRY (sex determining region Y)-box 15
chr2_+_113321939 0.25 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr6_+_155470243 0.25 ENST00000456877.2
ENST00000528391.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr19_+_1452188 0.25 ENST00000587149.1
APC2
adenomatosis polyposis coli 2
chr20_+_42839722 0.24 ENST00000442383.1
ENST00000435163.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr17_+_16593539 0.24 ENST00000340621.5
ENST00000399273.1
ENST00000443444.2
ENST00000360524.8
ENST00000456009.1
CCDC144A
coiled-coil domain containing 144A
chr11_+_61722629 0.23 ENST00000526988.1
BEST1
bestrophin 1
chrX_+_17755563 0.23 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr15_+_57998923 0.23 ENST00000380557.4
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr4_-_142253761 0.23 ENST00000511213.1
RP11-362F19.1
RP11-362F19.1
chr17_-_62499334 0.22 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr19_-_33716750 0.22 ENST00000253188.4
SLC7A10
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
chr4_+_106816592 0.22 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
NPNT
nephronectin
chr4_+_37892682 0.22 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr22_-_36924944 0.21 ENST00000405442.1
ENST00000402116.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr4_-_186347099 0.21 ENST00000505357.1
ENST00000264689.6
UFSP2
UFM1-specific peptidase 2
chr13_-_50510434 0.21 ENST00000361840.3
SPRYD7
SPRY domain containing 7
chr7_+_99102267 0.21 ENST00000326775.5
ENST00000451158.1
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr11_+_71498552 0.21 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
FAM86C1
family with sequence similarity 86, member C1
chr16_-_9030515 0.21 ENST00000535863.1
ENST00000381886.4
USP7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr3_-_81792780 0.21 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr17_+_11924129 0.21 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr8_+_66955648 0.21 ENST00000522619.1
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr12_+_122667658 0.20 ENST00000339777.4
ENST00000425921.1
LRRC43
leucine rich repeat containing 43
chr2_+_101437487 0.20 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr13_-_64650144 0.20 ENST00000456627.1
LINC00355
long intergenic non-protein coding RNA 355
chr4_+_146403912 0.20 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr13_-_50510622 0.20 ENST00000378195.2
SPRYD7
SPRY domain containing 7
chr4_-_4543700 0.20 ENST00000505286.1
ENST00000306200.2
STX18
syntaxin 18
chr3_-_52868931 0.20 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr20_-_52210368 0.19 ENST00000371471.2
ZNF217
zinc finger protein 217
chr10_-_12084770 0.19 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr4_+_164415594 0.19 ENST00000509657.1
ENST00000358572.5
TMA16
translation machinery associated 16 homolog (S. cerevisiae)
chr10_+_60094735 0.19 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr12_+_9142131 0.18 ENST00000356986.3
ENST00000266551.4
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr17_+_29421987 0.18 ENST00000431387.4
NF1
neurofibromin 1
chr22_-_23922410 0.18 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr1_+_153600869 0.18 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chrX_-_107334790 0.18 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr3_+_122296465 0.18 ENST00000483793.1
PARP15
poly (ADP-ribose) polymerase family, member 15
chr4_+_186347388 0.17 ENST00000511138.1
ENST00000511581.1
C4orf47
chromosome 4 open reading frame 47
chr14_+_58666824 0.17 ENST00000254286.4
ACTR10
actin-related protein 10 homolog (S. cerevisiae)
chr16_+_56970567 0.17 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr20_+_34802295 0.17 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr6_+_150070857 0.17 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr20_-_3687775 0.17 ENST00000344754.4
ENST00000202578.4
SIGLEC1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr3_-_105588231 0.17 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr16_+_85936295 0.17 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chr6_+_13182751 0.17 ENST00000415087.1
PHACTR1
phosphatase and actin regulator 1
chr13_+_41635617 0.17 ENST00000542082.1
WBP4
WW domain binding protein 4
chr21_+_37692481 0.16 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3
chr2_+_177053307 0.16 ENST00000331462.4
HOXD1
homeobox D1
chr19_+_11406821 0.16 ENST00000316737.1
ENST00000592955.1
ENST00000590327.1
TSPAN16
tetraspanin 16
chr11_-_82997420 0.16 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr2_-_234763105 0.16 ENST00000454020.1
HJURP
Holliday junction recognition protein
chr1_+_202976493 0.16 ENST00000367242.3
TMEM183A
transmembrane protein 183A
chr1_-_150669500 0.16 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr7_-_76255444 0.15 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr6_-_13711773 0.15 ENST00000011619.3
RANBP9
RAN binding protein 9
chr1_+_78354330 0.15 ENST00000440324.1
NEXN
nexilin (F actin binding protein)
chrX_+_17755696 0.15 ENST00000419185.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr15_+_57998821 0.15 ENST00000299638.3
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr2_-_191115229 0.15 ENST00000409820.2
ENST00000410045.1
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr8_-_141728760 0.15 ENST00000430260.2
PTK2
protein tyrosine kinase 2
chr19_-_50528392 0.15 ENST00000600137.1
ENST00000597215.1
VRK3
vaccinia related kinase 3
chr7_-_132766800 0.15 ENST00000542753.1
ENST00000448878.1
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr4_+_106816644 0.15 ENST00000506666.1
ENST00000503451.1
NPNT
nephronectin
chrX_-_108868390 0.15 ENST00000372101.2
KCNE1L
KCNE1-like
chr8_-_82633476 0.15 ENST00000518419.1
ENST00000517588.1
ENST00000521895.1
ENST00000520076.1
ENST00000519523.1
ENST00000522520.1
ENST00000521287.1
ENST00000523096.1
ENST00000220669.5
ENST00000517450.1
ZFAND1
zinc finger, AN1-type domain 1
chr1_-_94374946 0.15 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr11_+_47270436 0.15 ENST00000395397.3
ENST00000405576.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr3_+_141106643 0.15 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr1_-_226076843 0.15 ENST00000272134.5
LEFTY1
left-right determination factor 1
chr6_+_22221010 0.15 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr2_-_17981462 0.15 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr22_+_31277661 0.14 ENST00000454145.1
ENST00000453621.1
ENST00000431368.1
ENST00000535268.1
OSBP2
oxysterol binding protein 2
chr10_+_52499682 0.14 ENST00000185907.9
ENST00000374006.1
ASAH2B
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
chr12_-_68845165 0.14 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2
RP11-81H14.2
chr14_-_45431091 0.14 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr6_-_30080876 0.14 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr17_-_7081435 0.14 ENST00000380920.4
ASGR1
asialoglycoprotein receptor 1
chr5_-_34043310 0.14 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr5_+_125967372 0.14 ENST00000357147.3
C5orf48
chromosome 5 open reading frame 48
chr5_+_170288856 0.14 ENST00000523189.1
RANBP17
RAN binding protein 17
chr18_-_55470320 0.14 ENST00000536015.1
ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr18_+_158513 0.14 ENST00000400266.3
ENST00000580410.1
ENST00000383589.2
ENST00000261601.7
USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr3_+_167453493 0.14 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_+_33701707 0.14 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_14075865 0.14 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr10_-_28571015 0.14 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr14_+_31091511 0.14 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
SCFD1
sec1 family domain containing 1
chrX_-_107334750 0.14 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr19_-_43702231 0.14 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr1_+_78354297 0.14 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr18_+_56807096 0.14 ENST00000588875.1
SEC11C
SEC11 homolog C (S. cerevisiae)
chr11_+_7597639 0.13 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_+_143772060 0.13 ENST00000367591.4
PEX3
peroxisomal biogenesis factor 3
chr3_+_145782358 0.13 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr12_-_52845910 0.13 ENST00000252252.3
KRT6B
keratin 6B
chr7_-_132766818 0.13 ENST00000262570.5
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr3_-_176915215 0.13 ENST00000457928.2
ENST00000422442.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr16_-_5147743 0.13 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
FAM86A
family with sequence similarity 86, member A
chr12_-_105352080 0.13 ENST00000433540.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr17_-_63052929 0.13 ENST00000439174.2
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr22_+_32754139 0.13 ENST00000382088.3
RFPL3
ret finger protein-like 3
chr1_+_25757376 0.13 ENST00000399766.3
ENST00000399763.3
ENST00000374343.4
TMEM57
transmembrane protein 57
chr17_-_7193711 0.13 ENST00000571464.1
YBX2
Y box binding protein 2
chr2_+_63816126 0.13 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr3_-_10332416 0.12 ENST00000450603.1
ENST00000449554.2
GHRL
ghrelin/obestatin prepropeptide
chr12_+_16500571 0.12 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr2_+_74361599 0.12 ENST00000401851.1
MGC10955
MGC10955
chr22_+_44351419 0.12 ENST00000396202.3
SAMM50
SAMM50 sorting and assembly machinery component
chr3_-_105587879 0.12 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr15_+_63796779 0.12 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
USP3
ubiquitin specific peptidase 3
chr11_-_18656028 0.12 ENST00000336349.5
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr1_-_31230650 0.12 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr3_+_179065474 0.12 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr2_-_75745823 0.12 ENST00000452003.1
EVA1A
eva-1 homolog A (C. elegans)
chr11_-_88070920 0.12 ENST00000524463.1
ENST00000227266.5
CTSC
cathepsin C
chr20_+_30327063 0.12 ENST00000300403.6
ENST00000340513.4
TPX2
TPX2, microtubule-associated
chr19_-_17185848 0.12 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chr12_-_10875831 0.12 ENST00000279550.7
ENST00000228251.4
YBX3
Y box binding protein 3
chr3_+_169684553 0.12 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr11_-_62457371 0.12 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr12_+_112563335 0.12 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr10_+_35415978 0.12 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM
cAMP responsive element modulator
chr17_+_34848049 0.12 ENST00000588902.1
ENST00000591067.1
ZNHIT3
zinc finger, HIT-type containing 3
chr16_+_16484691 0.12 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr5_-_142784003 0.12 ENST00000416954.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_+_77681075 0.11 ENST00000397549.2
CTD-2116F7.1
CTD-2116F7.1
chr16_-_11485922 0.11 ENST00000599216.1
CTD-3088G3.8
Protein LOC388210
chrX_+_107334895 0.11 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr5_-_179050066 0.11 ENST00000329433.6
ENST00000510411.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr19_+_11651942 0.11 ENST00000587087.1
CNN1
calponin 1, basic, smooth muscle
chr11_-_64512803 0.11 ENST00000377489.1
ENST00000354024.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr6_-_41673552 0.11 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr1_+_46859933 0.11 ENST00000243167.8
FAAH
fatty acid amide hydrolase
chr20_-_23030296 0.11 ENST00000377103.2
THBD
thrombomodulin
chrX_-_16887963 0.11 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr17_-_39623681 0.11 ENST00000225899.3
KRT32
keratin 32
chr18_+_21529811 0.11 ENST00000588004.1
LAMA3
laminin, alpha 3
chr6_+_44184653 0.11 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
RP1-302G2.5
chr8_+_19171128 0.11 ENST00000265807.3
SH2D4A
SH2 domain containing 4A
chr15_+_44084503 0.11 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2
small EDRK-rich factor 2
chr11_+_6947720 0.11 ENST00000414517.2
ZNF215
zinc finger protein 215
chr22_+_44351301 0.11 ENST00000350028.4
SAMM50
SAMM50 sorting and assembly machinery component
chr15_+_63340775 0.11 ENST00000559281.1
ENST00000317516.7
TPM1
tropomyosin 1 (alpha)
chr17_+_7462103 0.11 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_31531121 0.10 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr16_+_18995249 0.10 ENST00000569532.1
ENST00000304381.5
TMC7
transmembrane channel-like 7
chr2_+_231280954 0.10 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen
chr17_+_29421900 0.10 ENST00000358273.4
ENST00000356175.3
NF1
neurofibromin 1
chr21_-_10990830 0.10 ENST00000361285.4
ENST00000342420.5
ENST00000328758.5
TPTE
transmembrane phosphatase with tensin homology
chr6_+_31555045 0.10 ENST00000396101.3
ENST00000490742.1
LST1
leukocyte specific transcript 1
chr7_-_6523755 0.10 ENST00000436575.1
ENST00000258739.4
DAGLB
KDELR2
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr2_+_231280908 0.10 ENST00000427101.2
ENST00000432979.1
SP100
SP100 nuclear antigen
chr12_+_72233487 0.10 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1D15
TBC1 domain family, member 15
chr15_+_45028520 0.10 ENST00000329464.4
TRIM69
tripartite motif containing 69
chr6_+_150070831 0.10 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr15_+_93447675 0.10 ENST00000536619.1
CHD2
chromodomain helicase DNA binding protein 2
chr15_+_40987661 0.10 ENST00000526763.1
RAD51
RAD51 recombinase
chr17_+_7477040 0.10 ENST00000581384.1
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr7_+_87563557 0.10 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.4 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.4 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.3 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.2 GO:0048627 myoblast development(GO:0048627)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.2 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.0 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.2 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.0 0.2 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:1904344 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) gastric mucosal blood circulation(GO:1990768) small intestine smooth muscle contraction(GO:1990770)
0.0 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0070781 response to biotin(GO:0070781)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.1 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.1 GO:0008355 olfactory learning(GO:0008355)
0.0 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0044146 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0071638 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.3 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.4 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.1 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.2 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.1 GO:0031768 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.0 0.6 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.5 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation