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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TBX5

Z-value: 0.65

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Transcription factors associated with TBX5

Gene Symbol Gene ID Gene Info
TBX5
ENSG00000089225.15 T-box transcription factor 5

Activity profile of TBX5 motif

Sorted Z-values of TBX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_64068116 0.33 ENST00000480679.1
UGP2
UDP-glucose pyrophosphorylase 2
chr15_+_90319557 0.32 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr15_+_76030311 0.32 ENST00000543887.1
AC019294.1
AC019294.1
chr5_-_100238918 0.25 ENST00000451528.2
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr3_-_9811674 0.23 ENST00000411972.1
CAMK1
calcium/calmodulin-dependent protein kinase I
chr4_-_102268708 0.22 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_-_37051798 0.21 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr1_-_12679171 0.20 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr21_+_44866471 0.19 ENST00000448049.1
LINC00319
long intergenic non-protein coding RNA 319
chr8_-_99955042 0.19 ENST00000519420.1
STK3
serine/threonine kinase 3
chr7_+_100450328 0.19 ENST00000540482.1
ENST00000418037.1
ENST00000428758.1
ENST00000275729.3
ENST00000415287.1
ENST00000354161.3
ENST00000416675.1
SLC12A9
solute carrier family 12, member 9
chr5_-_180229791 0.18 ENST00000504671.1
ENST00000507384.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr19_+_1000418 0.17 ENST00000234389.3
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr15_-_90294523 0.17 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr19_-_42721819 0.17 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
DEDD2
death effector domain containing 2
chr6_-_72130472 0.17 ENST00000426635.2
LINC00472
long intergenic non-protein coding RNA 472
chr15_+_91416092 0.16 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr15_+_89182156 0.16 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_-_8059638 0.16 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1
period circadian clock 1
chr16_-_69385681 0.15 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr16_+_30675654 0.15 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr19_-_3500635 0.15 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chrX_-_49056635 0.15 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
SYP
synaptophysin
chr3_-_61237050 0.14 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT
fragile histidine triad
chr17_-_27230035 0.14 ENST00000378895.4
ENST00000394901.3
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr4_-_177116772 0.14 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr17_-_73937028 0.14 ENST00000586631.2
FBF1
Fas (TNFRSF6) binding factor 1
chr17_-_72968837 0.14 ENST00000581676.1
HID1
HID1 domain containing
chr19_-_49622348 0.14 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr12_+_109569155 0.14 ENST00000539864.1
ACACB
acetyl-CoA carboxylase beta
chr3_+_49726932 0.14 ENST00000327697.6
ENST00000432042.1
ENST00000454491.1
RNF123
ring finger protein 123
chr14_+_24779376 0.14 ENST00000530080.1
LTB4R2
leukotriene B4 receptor 2
chr19_-_47734448 0.14 ENST00000439096.2
BBC3
BCL2 binding component 3
chr16_-_67190152 0.13 ENST00000486556.1
TRADD
TNFRSF1A-associated via death domain
chr2_-_27486951 0.13 ENST00000432351.1
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr15_+_40733387 0.13 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chr22_-_39268192 0.13 ENST00000216083.6
CBX6
chromobox homolog 6
chrX_-_80377162 0.13 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr17_-_7297833 0.13 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr8_+_87111059 0.13 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr19_+_46531127 0.13 ENST00000601033.1
CTC-344H19.4
CTC-344H19.4
chrX_-_80377118 0.12 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr3_-_52719912 0.12 ENST00000420148.1
PBRM1
polybromo 1
chr6_-_30043539 0.12 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr20_+_306177 0.12 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr14_+_24779340 0.12 ENST00000533293.1
ENST00000543919.1
LTB4R2
leukotriene B4 receptor 2
chr19_+_18723660 0.12 ENST00000262817.3
TMEM59L
transmembrane protein 59-like
chr20_-_22565101 0.12 ENST00000419308.2
FOXA2
forkhead box A2
chr22_-_39268308 0.11 ENST00000407418.3
CBX6
chromobox homolog 6
chr17_+_68164752 0.11 ENST00000535240.1
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr19_-_49222956 0.11 ENST00000599703.1
ENST00000318083.6
ENST00000419611.1
ENST00000377367.3
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr17_+_79859985 0.11 ENST00000333383.7
NPB
neuropeptide B
chr2_+_149402009 0.11 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr16_-_11350036 0.11 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr11_-_45939565 0.10 ENST00000525192.1
ENST00000378750.5
PEX16
peroxisomal biogenesis factor 16
chr18_+_3450161 0.10 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr2_+_42275153 0.10 ENST00000294964.5
PKDCC
protein kinase domain containing, cytoplasmic
chr10_-_102279586 0.10 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B
SEC31 homolog B (S. cerevisiae)
chr22_-_36013368 0.10 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr7_-_55583740 0.10 ENST00000453256.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr3_-_49726486 0.10 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr2_-_176046391 0.10 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr5_-_180229833 0.09 ENST00000307826.4
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr16_+_3162557 0.09 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
ZNF205
zinc finger protein 205
chr12_+_52203789 0.09 ENST00000599343.1
AC068987.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr2_-_216003127 0.09 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_-_153521714 0.09 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr16_+_2820912 0.09 ENST00000570539.1
SRRM2
serine/arginine repetitive matrix 2
chr20_+_48884002 0.09 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr1_-_154934200 0.09 ENST00000368457.2
PYGO2
pygopus family PHD finger 2
chr3_+_52279737 0.09 ENST00000457351.2
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr11_+_120081475 0.09 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr14_+_85994943 0.09 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr7_+_2687173 0.09 ENST00000403167.1
TTYH3
tweety family member 3
chr1_+_154975110 0.08 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr16_-_2031464 0.08 ENST00000356120.4
ENST00000354249.4
NOXO1
NADPH oxidase organizer 1
chr2_+_171673417 0.08 ENST00000344257.5
GAD1
glutamate decarboxylase 1 (brain, 67kDa)
chr18_-_60985914 0.08 ENST00000589955.1
BCL2
B-cell CLL/lymphoma 2
chr20_+_306221 0.08 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr1_-_149982624 0.08 ENST00000417191.1
ENST00000369135.4
OTUD7B
OTU domain containing 7B
chr1_-_153518270 0.08 ENST00000354332.4
ENST00000368716.4
S100A4
S100 calcium binding protein A4
chr5_-_148758839 0.08 ENST00000261796.3
IL17B
interleukin 17B
chr11_+_73358594 0.08 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr17_+_58755184 0.08 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr1_+_8378140 0.08 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr19_-_39421377 0.08 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
SARS2
seryl-tRNA synthetase 2, mitochondrial
chr12_-_116714564 0.08 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr3_-_48632593 0.08 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr17_+_55183261 0.08 ENST00000576295.1
AKAP1
A kinase (PRKA) anchor protein 1
chr11_-_45939374 0.08 ENST00000533151.1
ENST00000241041.3
PEX16
peroxisomal biogenesis factor 16
chr17_-_15165825 0.08 ENST00000426385.3
PMP22
peripheral myelin protein 22
chr1_-_21620877 0.08 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr17_+_77020224 0.08 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr8_-_21988558 0.08 ENST00000312841.8
HR
hair growth associated
chr5_+_32712363 0.08 ENST00000507141.1
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr12_+_53645870 0.07 ENST00000329548.4
MFSD5
major facilitator superfamily domain containing 5
chr3_+_184056614 0.07 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chr1_-_44482979 0.07 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr3_-_52719810 0.07 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr22_-_20231207 0.07 ENST00000425986.1
RTN4R
reticulon 4 receptor
chr17_-_1029866 0.07 ENST00000570525.1
ABR
active BCR-related
chr4_-_140222358 0.07 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_-_8579030 0.07 ENST00000255616.8
ENST00000393927.4
ZNF414
zinc finger protein 414
chr2_+_171673072 0.07 ENST00000358196.3
ENST00000375272.1
GAD1
glutamate decarboxylase 1 (brain, 67kDa)
chr4_-_4249924 0.07 ENST00000254742.2
ENST00000382753.4
ENST00000540397.1
ENST00000538516.1
TMEM128
transmembrane protein 128
chr11_+_114310164 0.07 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2
RNA exonuclease 2
chrX_-_148713365 0.07 ENST00000511776.1
ENST00000507237.1
TMEM185A
transmembrane protein 185A
chr7_-_92146729 0.07 ENST00000541751.1
PEX1
peroxisomal biogenesis factor 1
chr18_+_54318893 0.07 ENST00000593058.1
WDR7
WD repeat domain 7
chr1_+_55464600 0.07 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr11_-_74660065 0.07 ENST00000525407.1
ENST00000528219.1
ENST00000531852.1
XRRA1
X-ray radiation resistance associated 1
chr12_+_57853918 0.07 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr22_-_30722912 0.07 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr21_-_46962379 0.07 ENST00000311124.4
ENST00000380010.4
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr16_+_57023406 0.07 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLRC5
NLR family, CARD domain containing 5
chr17_-_27229948 0.07 ENST00000426464.2
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr1_-_151119087 0.07 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr17_+_77020146 0.07 ENST00000579760.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr1_+_47901689 0.07 ENST00000334793.5
FOXD2
forkhead box D2
chr11_+_61129827 0.07 ENST00000542946.1
TMEM138
transmembrane protein 138
chr19_+_41107249 0.06 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr1_+_1981890 0.06 ENST00000378567.3
ENST00000468310.1
PRKCZ
protein kinase C, zeta
chr3_-_50360192 0.06 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
HYAL2
hyaluronoglucosaminidase 2
chr4_+_102268904 0.06 ENST00000527564.1
ENST00000529296.1
AP001816.1
Uncharacterized protein
chr19_+_48867652 0.06 ENST00000344846.2
SYNGR4
synaptogyrin 4
chr17_-_7232585 0.06 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4
neuralized E3 ubiquitin protein ligase 4
chr7_+_143318020 0.06 ENST00000444908.2
ENST00000518791.1
ENST00000411497.2
FAM115C
family with sequence similarity 115, member C
chr1_+_228395755 0.06 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr4_+_183065793 0.06 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr13_-_28545276 0.06 ENST00000381020.7
CDX2
caudal type homeobox 2
chr16_-_2205352 0.06 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr20_+_34020827 0.06 ENST00000374375.1
GDF5OS
growth differentiation factor 5 opposite strand
chr7_+_40174565 0.06 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10
succinylCoA:glutarate-CoA transferase
chrX_-_153775426 0.06 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr16_-_70285797 0.06 ENST00000435634.1
EXOSC6
exosome component 6
chr2_+_29336855 0.06 ENST00000404424.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr8_-_145060593 0.05 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr17_+_44668387 0.05 ENST00000576040.1
NSF
N-ethylmaleimide-sensitive factor
chr6_+_150464155 0.05 ENST00000361131.4
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr6_-_31619697 0.05 ENST00000434444.1
BAG6
BCL2-associated athanogene 6
chrX_-_83757399 0.05 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
HDX
highly divergent homeobox
chr2_-_169769787 0.05 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr1_-_204329013 0.05 ENST00000272203.3
ENST00000414478.1
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr20_+_48909240 0.05 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr1_-_6269448 0.05 ENST00000465335.1
RPL22
ribosomal protein L22
chr22_-_38539185 0.05 ENST00000452542.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr1_+_154975258 0.05 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr6_-_31619892 0.05 ENST00000454165.1
ENST00000428326.1
ENST00000452994.1
BAG6
BCL2-associated athanogene 6
chr5_+_82767284 0.05 ENST00000265077.3
VCAN
versican
chrX_+_102862834 0.05 ENST00000372627.5
ENST00000243286.3
TCEAL3
transcription elongation factor A (SII)-like 3
chr9_+_4662282 0.05 ENST00000381883.2
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr14_-_21994337 0.05 ENST00000537235.1
ENST00000450879.2
SALL2
spalt-like transcription factor 2
chr1_-_85930246 0.05 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr19_-_10213335 0.05 ENST00000592641.1
ENST00000253109.4
ANGPTL6
angiopoietin-like 6
chr17_+_37821593 0.05 ENST00000578283.1
TCAP
titin-cap
chr17_-_73937116 0.05 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
FBF1
Fas (TNFRSF6) binding factor 1
chrX_+_149887090 0.05 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr1_-_15735925 0.05 ENST00000427824.1
RP3-467K16.4
RP3-467K16.4
chr6_+_34204642 0.05 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr1_+_153963227 0.05 ENST00000368567.4
ENST00000392558.4
RPS27
ribosomal protein S27
chr19_-_16045220 0.05 ENST00000326742.8
CYP4F11
cytochrome P450, family 4, subfamily F, polypeptide 11
chr17_+_77020325 0.05 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr12_-_49351303 0.05 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr5_+_82767583 0.05 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN
versican
chr20_-_3185279 0.05 ENST00000354488.3
ENST00000380201.2
DDRGK1
DDRGK domain containing 1
chr19_-_42931567 0.05 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr19_-_14016877 0.05 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57
chromosome 19 open reading frame 57
chr10_+_104263743 0.05 ENST00000369902.3
ENST00000369899.2
ENST00000423559.2
SUFU
suppressor of fused homolog (Drosophila)
chr2_+_201994042 0.05 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_+_11696464 0.05 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr2_+_85646054 0.05 ENST00000389938.2
SH2D6
SH2 domain containing 6
chr1_-_157014865 0.05 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr14_-_24911868 0.04 ENST00000554698.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr11_+_7559485 0.04 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_-_130536774 0.04 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr5_-_473135 0.04 ENST00000342584.3
CTD-2228K2.5
Uncharacterized protein
chr17_-_46703826 0.04 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr5_-_176836577 0.04 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr1_+_155911480 0.04 ENST00000368318.3
RXFP4
relaxin/insulin-like family peptide receptor 4
chr12_-_28124903 0.04 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr12_+_57849048 0.04 ENST00000266646.2
INHBE
inhibin, beta E
chr20_-_30310336 0.04 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr19_+_16308711 0.04 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chrX_-_106960285 0.04 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr7_+_76139833 0.04 ENST00000257632.5
UPK3B
uroplakin 3B
chrX_-_128788914 0.04 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr22_-_46373004 0.04 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr5_-_142784888 0.04 ENST00000514699.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_+_57970469 0.04 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr16_+_2587998 0.04 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr8_-_144654918 0.04 ENST00000529971.1
MROH6
maestro heat-like repeat family member 6
chr12_+_1738363 0.04 ENST00000397196.2
WNT5B
wingless-type MMTV integration site family, member 5B
chr13_-_79177673 0.04 ENST00000377208.5
POU4F1
POU class 4 homeobox 1
chr1_+_156254070 0.04 ENST00000405535.2
ENST00000456810.1
TMEM79
transmembrane protein 79
chr1_+_168250194 0.04 ENST00000367821.3
TBX19
T-box 19
chr1_-_157015162 0.04 ENST00000368194.3
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr3_+_135741576 0.04 ENST00000334546.2
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr12_+_56511943 0.04 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
ZC3H10
ESYT1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr7_-_105319536 0.04 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr21_+_17214724 0.04 ENST00000449491.1
USP25
ubiquitin specific peptidase 25

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.2 GO:0090381 negative regulation of mesodermal cell fate specification(GO:0042662) cardiac cell fate determination(GO:0060913) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.2 GO:1905205 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0018352 glutamate decarboxylation to succinate(GO:0006540) protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.0 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.0 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.0 GO:0048633 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0043353 slow-twitch skeletal muscle fiber contraction(GO:0031444) enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.0 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.0 GO:0060535 trachea cartilage morphogenesis(GO:0060535) inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.3 GO:0001632 leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.0 0.3 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.0 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors