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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for TBX4
Z-value: 0.89
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Transcription factors associated with TBX4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TBX4 | hg19_v2_chr17_+_59529743_59529798 | -0.70 | 3.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_29033682 Show fit | 0.61 |
ENST00000379579.4
ENST00000334056.5 ENST00000449210.1 |
speedy/RINGO cell cycle regulator family member A |
|
| chr7_+_107220899 Show fit | 0.42 |
ENST00000379117.2
ENST00000473124.1 |
B-cell receptor-associated protein 29 |
|
| chr2_-_177684007 Show fit | 0.41 |
ENST00000451851.1
|
AC092162.1 |
|
| chr8_-_99954788 Show fit | 0.39 |
ENST00000523601.1
|
serine/threonine kinase 3 |
|
| chr10_+_94833642 Show fit | 0.37 |
ENST00000224356.4
ENST00000394139.1 |
cytochrome P450, family 26, subfamily A, polypeptide 1 |
|
| chr9_+_40028620 Show fit | 0.36 |
ENST00000426179.1
|
AL353791.1 |
|
| chr3_+_167453493 Show fit | 0.33 |
ENST00000295777.5
ENST00000472747.2 |
serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
|
| chr5_+_74807581 Show fit | 0.32 |
ENST00000241436.4
ENST00000352007.5 |
polymerase (DNA directed) kappa |
|
| chr8_-_123793048 Show fit | 0.31 |
ENST00000607710.1
|
RP11-44N11.2 |
|
| chr11_+_111749650 Show fit | 0.31 |
ENST00000528125.1
|
chromosome 11 open reading frame 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TBX4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.0 | 0.6 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 0.6 | GO:0007140 | male meiosis(GO:0007140) |
| 0.0 | 0.5 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.1 | 0.4 | GO:0016103 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
| 0.0 | 0.4 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.3 | GO:0031247 | actin rod assembly(GO:0031247) |
| 0.0 | 0.3 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.0 | 0.3 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.0 | 0.3 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.3 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 0.3 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.3 | GO:0071682 | endoplasmic reticulum chaperone complex(GO:0034663) endocytic vesicle lumen(GO:0071682) |
| 0.1 | 0.2 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.0 | 0.2 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.0 | 0.2 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.0 | 0.2 | GO:0042025 | host cell nucleus(GO:0042025) |
| 0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.1 | GO:0036194 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.4 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.0 | 0.3 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.3 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 0.3 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.2 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 0.0 | 0.2 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.0 | 0.2 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |