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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TBX15_MGA

Z-value: 0.79

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Transcription factors associated with TBX15_MGA

Gene Symbol Gene ID Gene Info
TBX15
ENSG00000092607.9 T-box transcription factor 15
MGA
ENSG00000174197.12 MAX dimerization protein MGA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX15hg19_v2_chr1_-_119530428_119530572-0.964.3e-02Click!
MGAhg19_v2_chr15_+_41913690_419137530.346.6e-01Click!

Activity profile of TBX15_MGA motif

Sorted Z-values of TBX15_MGA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_29033682 0.68 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA
speedy/RINGO cell cycle regulator family member A
chr19_+_46531127 0.48 ENST00000601033.1
CTC-344H19.4
CTC-344H19.4
chr9_+_102584128 0.44 ENST00000338488.4
ENST00000395097.2
NR4A3
nuclear receptor subfamily 4, group A, member 3
chr21_+_30502806 0.42 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr16_-_69418553 0.40 ENST00000569542.2
TERF2
telomeric repeat binding factor 2
chr11_+_111750206 0.38 ENST00000530214.1
ENST00000530799.1
C11orf1
chromosome 11 open reading frame 1
chr7_+_107220899 0.37 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr16_-_81110683 0.36 ENST00000565253.1
ENST00000378611.4
ENST00000299578.5
C16orf46
chromosome 16 open reading frame 46
chr11_+_111749650 0.34 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr12_-_120805872 0.33 ENST00000546985.1
MSI1
musashi RNA-binding protein 1
chr11_+_7559485 0.31 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr21_+_30503282 0.31 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr8_-_99954788 0.30 ENST00000523601.1
STK3
serine/threonine kinase 3
chr10_-_16563870 0.30 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr1_+_35734616 0.28 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr11_+_86511549 0.28 ENST00000533902.2
PRSS23
protease, serine, 23
chr2_-_177684007 0.27 ENST00000451851.1
AC092162.1
AC092162.1
chrX_+_46772065 0.26 ENST00000455411.1
PHF16
jade family PHD finger 3
chr11_+_111749942 0.26 ENST00000260276.3
C11orf1
chromosome 11 open reading frame 1
chr16_-_69418649 0.26 ENST00000566257.1
TERF2
telomeric repeat binding factor 2
chr3_+_167453493 0.25 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_-_61108449 0.25 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr2_-_157189180 0.25 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_+_228678550 0.24 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr2_+_62933001 0.24 ENST00000263991.5
ENST00000354487.3
EHBP1
EH domain binding protein 1
chr9_-_128003606 0.24 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr17_-_8066843 0.24 ENST00000404970.3
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr1_+_172502336 0.23 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chr13_-_48575376 0.23 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr2_-_85895295 0.23 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chr12_+_104324112 0.23 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr11_+_18477369 0.22 ENST00000396213.3
ENST00000280706.2
LDHAL6A
lactate dehydrogenase A-like 6A
chr15_-_83315874 0.22 ENST00000569257.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr17_-_1619491 0.21 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22HG
MIR22 host gene (non-protein coding)
chr10_-_92681033 0.21 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr14_+_90864504 0.20 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr7_+_107220660 0.20 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr11_-_85779971 0.20 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr7_-_27142290 0.20 ENST00000222718.5
HOXA2
homeobox A2
chr7_+_143013198 0.19 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr3_-_167452614 0.19 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
PDCD10
programmed cell death 10
chr13_-_48575443 0.19 ENST00000378654.3
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr3_-_49459865 0.19 ENST00000427987.1
AMT
aminomethyltransferase
chr4_+_57371509 0.19 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chr20_+_1115821 0.18 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr1_-_113247543 0.18 ENST00000414971.1
ENST00000534717.1
RHOC
ras homolog family member C
chrX_+_123095546 0.18 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr18_-_45457478 0.18 ENST00000402690.2
ENST00000356825.4
SMAD2
SMAD family member 2
chr7_-_27135591 0.18 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr5_+_74807581 0.18 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chrX_-_55515635 0.18 ENST00000500968.3
USP51
ubiquitin specific peptidase 51
chr5_-_34043310 0.18 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr3_+_142315294 0.17 ENST00000464320.1
PLS1
plastin 1
chr8_-_123793048 0.17 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr12_+_57854274 0.17 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr1_+_155911480 0.17 ENST00000368318.3
RXFP4
relaxin/insulin-like family peptide receptor 4
chr11_+_107643129 0.17 ENST00000447610.1
AP001024.2
Uncharacterized protein
chr11_+_122709200 0.17 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr1_-_156786634 0.17 ENST00000392306.2
ENST00000368199.3
SH2D2A
SH2 domain containing 2A
chr2_+_61108650 0.16 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr3_+_160117418 0.16 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chr7_-_76255444 0.16 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr11_-_85430088 0.16 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr19_+_45973120 0.16 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr3_-_49459878 0.16 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr19_-_10450328 0.16 ENST00000160262.5
ICAM3
intercellular adhesion molecule 3
chr5_+_172332220 0.16 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chrX_+_123095155 0.16 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr1_-_149889382 0.16 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr10_+_94833642 0.15 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chrX_+_16804544 0.15 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr19_+_35773242 0.15 ENST00000222304.3
HAMP
hepcidin antimicrobial peptide
chr1_-_226374373 0.15 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr22_-_39639021 0.15 ENST00000455790.1
PDGFB
platelet-derived growth factor beta polypeptide
chr1_+_38022572 0.15 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr2_-_175869936 0.15 ENST00000409900.3
CHN1
chimerin 1
chr17_+_57784826 0.15 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr17_+_79031415 0.15 ENST00000572073.1
ENST00000573677.1
BAIAP2
BAI1-associated protein 2
chr7_+_27282319 0.15 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr2_+_202937972 0.15 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr6_+_84563295 0.15 ENST00000369687.1
RIPPLY2
ripply transcriptional repressor 2
chr9_-_74979420 0.15 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr2_+_61108771 0.15 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr3_-_93747425 0.15 ENST00000315099.2
STX19
syntaxin 19
chr14_-_45603657 0.15 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr14_-_57960456 0.15 ENST00000534126.1
ENST00000422976.2
C14orf105
chromosome 14 open reading frame 105
chr1_+_182758900 0.15 ENST00000367555.1
ENST00000367554.3
NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr14_+_21467414 0.14 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr11_-_85430204 0.14 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr2_-_39664405 0.14 ENST00000341681.5
ENST00000263881.3
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr17_+_25958174 0.14 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr17_-_57784755 0.14 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
PTRH2
peptidyl-tRNA hydrolase 2
chr15_+_41913690 0.14 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr3_-_167452298 0.14 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chr6_+_30908747 0.14 ENST00000462446.1
ENST00000304311.2
DPCR1
diffuse panbronchiolitis critical region 1
chr7_+_141438393 0.14 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
SSBP1
single-stranded DNA binding protein 1, mitochondrial
chr3_+_142315225 0.14 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr5_+_113697983 0.14 ENST00000264773.3
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr17_+_42925270 0.14 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr8_-_17270809 0.14 ENST00000180173.5
ENST00000521857.1
MTMR7
myotubularin related protein 7
chr7_-_123673471 0.13 ENST00000455783.1
TMEM229A
transmembrane protein 229A
chr3_-_120170052 0.13 ENST00000295633.3
FSTL1
follistatin-like 1
chrX_-_106146547 0.13 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr10_+_94451574 0.13 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr3_-_167452262 0.13 ENST00000487947.2
PDCD10
programmed cell death 10
chr19_-_44405941 0.13 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr6_+_43739697 0.13 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr12_-_102133191 0.13 ENST00000392924.1
ENST00000266743.2
ENST00000392927.3
SYCP3
synaptonemal complex protein 3
chr1_+_16062820 0.12 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr6_+_108616243 0.12 ENST00000421954.1
LACE1
lactation elevated 1
chr2_-_175870085 0.12 ENST00000409156.3
CHN1
chimerin 1
chr3_-_167452703 0.12 ENST00000497056.2
ENST00000473645.2
PDCD10
programmed cell death 10
chr17_-_47755436 0.12 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP
speckle-type POZ protein
chr2_-_145090035 0.12 ENST00000542155.1
ENST00000241391.5
ENST00000463875.2
GTDC1
glycosyltransferase-like domain containing 1
chr1_-_156786530 0.12 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr7_-_72437484 0.12 ENST00000395244.1
TRIM74
tripartite motif containing 74
chr1_+_38022513 0.12 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr14_-_98444386 0.12 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr5_-_78809950 0.12 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr17_+_30771279 0.12 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chrX_-_19689106 0.12 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr11_+_19138670 0.12 ENST00000446113.2
ENST00000399351.3
ZDHHC13
zinc finger, DHHC-type containing 13
chr18_-_45457192 0.11 ENST00000586514.1
ENST00000591214.1
ENST00000589877.1
SMAD2
SMAD family member 2
chr2_+_219283815 0.11 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
VIL1
villin 1
chr6_+_79577189 0.11 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr11_-_7847519 0.11 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr13_-_48575401 0.11 ENST00000433022.1
ENST00000544100.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr5_-_114515734 0.11 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr11_+_117947724 0.11 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chr19_+_12862604 0.11 ENST00000553030.1
BEST2
bestrophin 2
chr13_-_52027134 0.11 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr15_+_101402041 0.11 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr21_-_42879909 0.11 ENST00000458356.1
ENST00000398585.3
ENST00000424093.1
TMPRSS2
transmembrane protease, serine 2
chr19_-_10450287 0.11 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr8_-_95907423 0.11 ENST00000396133.3
ENST00000308108.4
CCNE2
cyclin E2
chr21_+_27107672 0.11 ENST00000400075.3
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr6_-_41168920 0.11 ENST00000483722.1
TREML2
triggering receptor expressed on myeloid cells-like 2
chr2_+_172864490 0.10 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr4_+_26578293 0.10 ENST00000512840.1
TBC1D19
TBC1 domain family, member 19
chr4_+_111397216 0.10 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr1_+_26737253 0.10 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr5_+_74807886 0.10 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr21_-_42880075 0.10 ENST00000332149.5
TMPRSS2
transmembrane protease, serine 2
chr1_+_9599540 0.10 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr1_+_145507587 0.10 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr17_-_40333099 0.10 ENST00000607371.1
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr14_+_75746664 0.10 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr7_+_99102267 0.10 ENST00000326775.5
ENST00000451158.1
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr1_-_226076843 0.10 ENST00000272134.5
LEFTY1
left-right determination factor 1
chr9_+_17134980 0.10 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr3_-_197024394 0.10 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr10_+_95256356 0.10 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr21_-_27107198 0.10 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr16_+_57220193 0.10 ENST00000564435.1
ENST00000562959.1
ENST00000394420.4
ENST00000568505.2
ENST00000537866.1
RSPRY1
ring finger and SPRY domain containing 1
chr20_-_3644046 0.10 ENST00000290417.2
ENST00000319242.3
GFRA4
GDNF family receptor alpha 4
chr9_+_131452239 0.10 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr9_+_40028620 0.10 ENST00000426179.1
AL353791.1
AL353791.1
chrX_+_21959108 0.10 ENST00000457085.1
SMS
spermine synthase
chr13_+_98628886 0.10 ENST00000490680.1
ENST00000539640.1
ENST00000403772.3
IPO5
importin 5
chr17_-_47755338 0.10 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP
speckle-type POZ protein
chr21_-_27107344 0.10 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chrX_+_46771711 0.09 ENST00000424392.1
ENST00000397189.1
PHF16
jade family PHD finger 3
chr12_-_56120838 0.09 ENST00000548160.1
CD63
CD63 molecule
chr12_-_107380910 0.09 ENST00000392830.2
ENST00000240050.4
MTERFD3
MTERF domain containing 3
chr12_-_13529594 0.09 ENST00000539026.1
C12orf36
chromosome 12 open reading frame 36
chr2_+_219081817 0.09 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr11_-_85430163 0.09 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr12_-_46663734 0.09 ENST00000550173.1
SLC38A1
solute carrier family 38, member 1
chr1_+_172502244 0.09 ENST00000610051.1
SUCO
SUN domain containing ossification factor
chr2_+_62932779 0.09 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1
EH domain binding protein 1
chr12_-_49412525 0.09 ENST00000551121.1
ENST00000552212.1
ENST00000548605.1
ENST00000548950.1
ENST00000547125.1
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr4_-_184241927 0.09 ENST00000323319.5
CLDN22
claudin 22
chr11_-_67276100 0.09 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr2_-_74776586 0.09 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr19_+_19779589 0.09 ENST00000541458.1
ZNF101
zinc finger protein 101
chr1_+_26737292 0.09 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr17_-_77179487 0.09 ENST00000580508.1
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr1_+_200993071 0.09 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chrX_-_118739835 0.09 ENST00000542113.1
ENST00000304449.5
NKRF
NFKB repressing factor
chr9_-_37384431 0.08 ENST00000452923.1
RP11-397D12.4
RP11-397D12.4
chr4_+_146403912 0.08 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr6_-_84937314 0.08 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr8_-_101719159 0.08 ENST00000520868.1
ENST00000522658.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr12_+_93965609 0.08 ENST00000549887.1
ENST00000551556.1
SOCS2
suppressor of cytokine signaling 2
chr19_-_51875894 0.08 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chrX_+_135230712 0.08 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr8_-_124253576 0.08 ENST00000276704.4
C8orf76
chromosome 8 open reading frame 76
chr13_-_46543805 0.08 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr19_+_45973360 0.08 ENST00000589593.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr9_+_140032842 0.08 ENST00000371561.3
ENST00000315048.3
GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr6_+_45390222 0.08 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr2_+_43864387 0.08 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr16_-_67965756 0.08 ENST00000571044.1
ENST00000571605.1
CTRL
chymotrypsin-like
chr14_+_53196872 0.08 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr11_+_17568920 0.08 ENST00000399391.2
OTOG
otogelin
chr3_+_63805017 0.08 ENST00000295896.8
C3orf49
chromosome 3 open reading frame 49
chr10_+_49514698 0.08 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr14_+_93260569 0.08 ENST00000163416.2
GOLGA5
golgin A5
chr1_+_178482262 0.08 ENST00000367641.3
ENST00000367639.1
TEX35
testis expressed 35
chr5_-_179719048 0.08 ENST00000523583.1
ENST00000393360.3
ENST00000455781.1
ENST00000347470.4
ENST00000452135.2
ENST00000343111.6
MAPK9
mitogen-activated protein kinase 9

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX15_MGA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.4 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.5 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 0.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.2 GO:0045360 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.2 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:1990641 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0002519 natural killer cell tolerance induction(GO:0002519) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.1 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.2 GO:0090678 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.0 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:1905069 allantois development(GO:1905069)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:1900165 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638) negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0070972 protein localization to endoplasmic reticulum(GO:0070972)
0.0 0.1 GO:0010983 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:0044266 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.2 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.7 GO:0007140 male meiosis(GO:0007140)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:0060032 notochord regression(GO:0060032)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0060996 dendritic spine development(GO:0060996)
0.0 0.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.0 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.6 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.0 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL