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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for TBP

Z-value: 3.24

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Transcription factors associated with TBP

Gene Symbol Gene ID Gene Info
TBP
ENSG00000112592.8 TATA-box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBPhg19_v2_chr6_+_170863672_170863698-0.415.9e-01Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_149785236 2.96 ENST00000331491.1
HIST2H3D
histone cluster 2, H3d
chr6_+_26156551 2.75 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr6_-_26235206 2.70 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr6_-_26032288 2.23 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr6_+_27114861 2.19 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr5_+_53686658 2.15 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr6_+_26104104 2.06 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr6_-_26189304 1.98 ENST00000340756.2
HIST1H4D
histone cluster 1, H4d
chr6_-_26033796 1.96 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr6_-_27835357 1.88 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr6_+_26045603 1.77 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr6_-_26250835 1.71 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr6_-_26043885 1.60 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr8_-_6735451 1.54 ENST00000297439.3
DEFB1
defensin, beta 1
chr6_-_26216872 1.52 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr17_-_34207295 1.48 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr18_+_68002675 1.44 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr6_+_26183958 1.43 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr7_+_143013198 1.40 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr9_-_21077939 1.39 ENST00000380232.2
IFNB1
interferon, beta 1, fibroblast
chr9_-_35658007 1.38 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr17_-_39661849 1.37 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr6_-_27860956 1.37 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr7_+_112120908 1.34 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
LSMEM1
leucine-rich single-pass membrane protein 1
chr11_+_65266507 1.27 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr6_-_27100529 1.22 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr9_-_140142222 1.17 ENST00000344774.4
ENST00000388932.2
FAM166A
family with sequence similarity 166, member A
chr12_+_52695617 1.14 ENST00000293525.5
KRT86
keratin 86
chr6_-_26285737 1.14 ENST00000377727.1
ENST00000289352.1
HIST1H4H
histone cluster 1, H4h
chr17_+_16284749 1.13 ENST00000578706.1
UBB
ubiquitin B
chr11_-_18270182 1.13 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr14_+_75745477 1.13 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr19_+_35773242 1.13 ENST00000222304.3
HAMP
hepcidin antimicrobial peptide
chr1_+_33546714 1.11 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
ADC
arginine decarboxylase
chr11_+_18287801 1.06 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr17_-_79792909 1.04 ENST00000330261.4
ENST00000570394.1
PPP1R27
protein phosphatase 1, regulatory subunit 27
chr1_-_149812765 1.03 ENST00000369158.1
HIST2H3C
histone cluster 2, H3c
chr6_+_26021869 1.03 ENST00000359907.3
HIST1H4A
histone cluster 1, H4a
chr6_-_26124138 0.99 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr10_+_96698406 0.99 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr17_+_74729060 0.97 ENST00000587459.1
RP11-318A15.7
Uncharacterized protein
chr6_+_26204825 0.96 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr11_-_67415048 0.94 ENST00000529256.1
ACY3
aspartoacylase (aminocyclase) 3
chr17_+_16284604 0.93 ENST00000395839.1
ENST00000395837.1
UBB
ubiquitin B
chr17_-_39661947 0.93 ENST00000590425.1
KRT13
keratin 13
chr12_-_49582593 0.87 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr1_-_23886285 0.87 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr12_+_11905413 0.86 ENST00000545027.1
ETV6
ets variant 6
chr7_-_3214287 0.86 ENST00000404626.3
AC091801.1
LOC392621; Uncharacterized protein
chr6_+_27100811 0.84 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr11_-_9025541 0.83 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr6_-_27840099 0.77 ENST00000328488.2
HIST1H3I
histone cluster 1, H3i
chr8_+_99956759 0.76 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr1_-_149814478 0.76 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr9_-_21228221 0.76 ENST00000413767.2
IFNA17
interferon, alpha 17
chr6_+_27107053 0.75 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr7_+_116593433 0.73 ENST00000323984.3
ENST00000393449.1
ST7
suppression of tumorigenicity 7
chr1_+_149822620 0.73 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr6_+_27833034 0.72 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr7_+_116593292 0.71 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7
suppression of tumorigenicity 7
chr6_+_26199737 0.71 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr1_-_207226313 0.70 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr5_-_158757895 0.69 ENST00000231228.2
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chrX_+_18725758 0.69 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr2_-_27531313 0.69 ENST00000296099.2
UCN
urocortin
chr11_+_18287721 0.68 ENST00000356524.4
SAA1
serum amyloid A1
chr10_-_8095412 0.67 ENST00000458727.1
ENST00000355358.1
RP11-379F12.3
GATA3-AS1
RP11-379F12.3
GATA3 antisense RNA 1
chr19_+_2476116 0.67 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr4_+_74606223 0.66 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr6_-_52859968 0.65 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr1_+_202830876 0.64 ENST00000456105.2
RP11-480I12.7
RP11-480I12.7
chr1_+_92414952 0.63 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT
bromodomain, testis-specific
chr7_+_115862858 0.63 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr16_-_67965756 0.63 ENST00000571044.1
ENST00000571605.1
CTRL
chymotrypsin-like
chr17_+_39421591 0.63 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr1_-_1009683 0.62 ENST00000453464.2
RNF223
ring finger protein 223
chr17_-_73150629 0.62 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chr1_-_20755140 0.62 ENST00000418743.1
ENST00000426428.1
RP4-749H3.1
long intergenic non-protein coding RNA 1141
chr17_-_73150599 0.61 ENST00000392566.2
ENST00000581874.1
HN1
hematological and neurological expressed 1
chr17_+_16284104 0.60 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB
ubiquitin B
chr16_-_56701933 0.59 ENST00000568675.1
ENST00000569500.1
ENST00000444837.2
ENST00000379811.3
MT1G
metallothionein 1G
chr20_+_2276639 0.59 ENST00000381458.5
TGM3
transglutaminase 3
chr17_-_38545799 0.58 ENST00000577541.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr6_-_134495992 0.56 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_39405939 0.55 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr18_-_33077868 0.55 ENST00000590757.1
ENST00000592173.1
ENST00000441607.2
ENST00000587450.1
ENST00000589258.1
INO80C
RP11-322E11.6
INO80 complex subunit C
Uncharacterized protein
chr22_-_40929812 0.55 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr11_+_62432777 0.54 ENST00000532971.1
METTL12
methyltransferase like 12
chr19_+_8386371 0.54 ENST00000600659.2
RPS28
ribosomal protein S28
chr11_+_62623621 0.54 ENST00000535296.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr8_-_23021533 0.53 ENST00000312584.3
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr6_-_27806117 0.53 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr12_-_52845910 0.52 ENST00000252252.3
KRT6B
keratin 6B
chr19_+_13049413 0.52 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr17_+_79849872 0.52 ENST00000584197.1
ENST00000583839.1
ANAPC11
anaphase promoting complex subunit 11
chr1_-_179457805 0.51 ENST00000600581.1
AL160286.1
Uncharacterized protein
chr6_+_27861190 0.50 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr20_+_30193083 0.50 ENST00000376112.3
ENST00000376105.3
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr3_+_193853927 0.50 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr3_-_170587815 0.50 ENST00000466674.1
RPL22L1
ribosomal protein L22-like 1
chr6_-_116833500 0.49 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr11_-_36531774 0.49 ENST00000348124.5
ENST00000526995.1
TRAF6
TNF receptor-associated factor 6, E3 ubiquitin protein ligase
chr5_-_74162739 0.49 ENST00000513277.1
FAM169A
family with sequence similarity 169, member A
chrX_+_72783026 0.48 ENST00000373504.6
ENST00000373502.5
CHIC1
cysteine-rich hydrophobic domain 1
chr3_+_62304712 0.48 ENST00000494481.1
C3orf14
chromosome 3 open reading frame 14
chrX_-_55515635 0.47 ENST00000500968.3
USP51
ubiquitin specific peptidase 51
chr19_+_36347787 0.47 ENST00000347900.6
ENST00000360202.5
KIRREL2
kin of IRRE like 2 (Drosophila)
chr19_+_12944722 0.47 ENST00000591495.1
MAST1
microtubule associated serine/threonine kinase 1
chr8_-_30002179 0.45 ENST00000320542.3
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr11_+_62623544 0.45 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr15_+_76629064 0.45 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr19_+_46367518 0.44 ENST00000302177.2
FOXA3
forkhead box A3
chr6_+_30585486 0.44 ENST00000259873.4
ENST00000506373.2
MRPS18B
mitochondrial ribosomal protein S18B
chr11_+_62623512 0.44 ENST00000377892.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr17_+_77021702 0.44 ENST00000392445.2
ENST00000354124.3
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_79849523 0.44 ENST00000572639.1
ENST00000579978.1
ENST00000344877.5
ENST00000582222.1
ENST00000577425.1
ENST00000571024.2
ENST00000574924.2
ENST00000572851.2
ENST00000357385.3
ENST00000584314.1
ENST00000571874.2
ENST00000578550.1
ENST00000577747.1
ENST00000579133.1
ANAPC11
anaphase promoting complex subunit 11
chr8_-_82598067 0.43 ENST00000523942.1
ENST00000522997.1
IMPA1
inositol(myo)-1(or 4)-monophosphatase 1
chr6_-_3227877 0.43 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr3_-_170587974 0.43 ENST00000463836.1
RPL22L1
ribosomal protein L22-like 1
chr6_+_64282447 0.43 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr12_-_21757774 0.43 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr3_-_172859017 0.42 ENST00000351008.3
SPATA16
spermatogenesis associated 16
chr7_+_75931861 0.42 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr17_+_16284399 0.41 ENST00000535788.1
UBB
ubiquitin B
chr12_-_49393092 0.41 ENST00000421952.2
DDN
dendrin
chr19_-_6720686 0.41 ENST00000245907.6
C3
complement component 3
chr11_-_76155700 0.41 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr19_+_1524072 0.41 ENST00000454744.2
PLK5
polo-like kinase 5
chr17_+_79849782 0.41 ENST00000392376.3
ANAPC11
anaphase promoting complex subunit 11
chr1_-_95007193 0.40 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr17_+_29248918 0.40 ENST00000581548.1
ENST00000580525.1
ADAP2
ArfGAP with dual PH domains 2
chr10_-_101190202 0.40 ENST00000543866.1
ENST00000370508.5
GOT1
glutamic-oxaloacetic transaminase 1, soluble
chrX_-_7895755 0.39 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
PNPLA4
patatin-like phospholipase domain containing 4
chr19_-_6767516 0.39 ENST00000245908.6
SH2D3A
SH2 domain containing 3A
chr19_+_50922187 0.39 ENST00000595883.1
ENST00000597855.1
ENST00000596074.1
ENST00000439922.2
ENST00000594685.1
ENST00000270632.7
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr3_+_70048881 0.39 ENST00000483525.1
RP11-460N16.1
RP11-460N16.1
chr1_-_117753540 0.38 ENST00000328189.3
ENST00000369458.3
VTCN1
V-set domain containing T cell activation inhibitor 1
chr12_-_49582837 0.37 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
TUBA1A
tubulin, alpha 1a
chr11_+_3875757 0.37 ENST00000525403.1
STIM1
stromal interaction molecule 1
chr2_-_21266816 0.36 ENST00000399256.4
APOB
apolipoprotein B
chr8_+_120428546 0.36 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr6_+_111195973 0.36 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr1_-_11907829 0.36 ENST00000376480.3
NPPA
natriuretic peptide A
chr13_+_27844464 0.36 ENST00000241463.4
RASL11A
RAS-like, family 11, member A
chr1_-_226187013 0.36 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr21_-_28217721 0.36 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_+_40942887 0.35 ENST00000372706.1
ZFP69
ZFP69 zinc finger protein
chr8_+_1993173 0.35 ENST00000523438.1
MYOM2
myomesin 2
chr4_+_74735102 0.35 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr12_+_13044787 0.35 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr18_+_616711 0.35 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr1_+_86046433 0.35 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr22_+_19706958 0.34 ENST00000395109.2
SEPT5
septin 5
chr9_-_130639997 0.34 ENST00000373176.1
AK1
adenylate kinase 1
chr6_+_122720681 0.34 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr17_-_10560619 0.34 ENST00000583535.1
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr11_-_4719072 0.34 ENST00000396950.3
ENST00000532598.1
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr22_-_19466732 0.34 ENST00000263202.10
ENST00000360834.4
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr17_+_7184986 0.33 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr20_-_23731893 0.33 ENST00000398402.1
CST1
cystatin SN
chr1_-_71513471 0.33 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
PTGER3
prostaglandin E receptor 3 (subtype EP3)
chr12_-_118796910 0.33 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr21_-_43786634 0.33 ENST00000291527.2
TFF1
trefoil factor 1
chr16_+_89989687 0.33 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
TUBB3
Tubulin beta-3 chain
chr6_-_33239712 0.32 ENST00000436044.2
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr4_-_84035905 0.32 ENST00000311507.4
PLAC8
placenta-specific 8
chr7_+_72742178 0.32 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr17_-_39538550 0.32 ENST00000394001.1
KRT34
keratin 34
chr9_+_135937365 0.31 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr1_+_225140372 0.31 ENST00000366848.1
ENST00000439375.2
DNAH14
dynein, axonemal, heavy chain 14
chr1_+_173837488 0.30 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37
zinc finger and BTB domain containing 37
chr17_-_39781054 0.30 ENST00000463128.1
KRT17
keratin 17
chr16_+_56691911 0.30 ENST00000568475.1
MT1F
metallothionein 1F
chr19_+_2269485 0.30 ENST00000582888.4
ENST00000602676.2
ENST00000322297.4
ENST00000583542.4
OAZ1
ornithine decarboxylase antizyme 1
chr17_-_48278983 0.30 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr20_+_18488528 0.30 ENST00000377465.1
SEC23B
Sec23 homolog B (S. cerevisiae)
chr20_-_43753104 0.29 ENST00000372785.3
WFDC12
WAP four-disulfide core domain 12
chr7_-_134143841 0.29 ENST00000285930.4
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr8_+_1993152 0.29 ENST00000262113.4
MYOM2
myomesin 2
chr6_-_33239612 0.29 ENST00000482399.1
ENST00000445902.2
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr9_+_124088860 0.28 ENST00000373806.1
GSN
gelsolin
chr3_+_62304648 0.28 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr20_+_55926625 0.28 ENST00000452119.1
RAE1
ribonucleic acid export 1
chr19_-_55919087 0.28 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S
ubiquitin-conjugating enzyme E2S
chr3_-_96337000 0.28 ENST00000600213.2
MTRNR2L12
MT-RNR2-like 12 (pseudogene)
chr2_-_106054952 0.28 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr17_+_80317121 0.28 ENST00000333437.4
TEX19
testis expressed 19
chr3_+_142342228 0.28 ENST00000337777.3
PLS1
plastin 1
chr17_+_38497640 0.28 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr7_-_30066233 0.28 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr16_-_2014804 0.27 ENST00000526522.1
ENST00000527302.1
ENST00000529806.1
ENST00000563194.1
ENST00000343262.4
RPS2
ribosomal protein S2
chr3_+_57882061 0.27 ENST00000461354.1
ENST00000466255.1
SLMAP
sarcolemma associated protein
chr9_-_118417 0.27 ENST00000382500.2
FOXD4
forkhead box D4
chr3_-_129035120 0.27 ENST00000333762.4
H1FX
H1 histone family, member X
chr6_+_159290917 0.26 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr6_+_10748019 0.26 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
SYCP2L
TMEM14B
synaptonemal complex protein 2-like
transmembrane protein 14B
chr6_+_36562132 0.26 ENST00000373715.6
ENST00000339436.7
SRSF3
serine/arginine-rich splicing factor 3
chr22_-_19466454 0.26 ENST00000494054.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr8_-_143696833 0.26 ENST00000356613.2
ARC
activity-regulated cytoskeleton-associated protein
chr15_+_49715293 0.26 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.5 1.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.4 3.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 1.2 GO:1903413 cellular response to bile acid(GO:1903413)
0.4 3.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.3 1.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 1.4 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.3 0.8 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.2 0.6 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.2 1.4 GO:0060356 leucine import(GO:0060356)
0.2 0.6 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.2 0.7 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.2 0.5 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.2 0.5 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) regulation of timing of neuron differentiation(GO:0060164) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.2 1.9 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.4 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.7 GO:0019401 alditol biosynthetic process(GO:0019401)
0.1 0.7 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1 0.4 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 1.0 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 1.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 2.2 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 0.1 GO:1903989 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.6 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.5 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.3 GO:0044691 tooth eruption(GO:0044691)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 1.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 1.4 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.3 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.1 0.3 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.2 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.4 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.6 GO:0060591 chondroblast differentiation(GO:0060591)
0.1 0.3 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.3 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.2 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.3 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.2 GO:0060437 lung growth(GO:0060437)
0.1 0.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.4 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.4 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 1.7 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.2 GO:0052042 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.0 0.1 GO:0030474 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 5.4 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.9 GO:0030903 notochord development(GO:0030903)
0.0 0.4 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.6 GO:0042117 monocyte activation(GO:0042117)
0.0 0.2 GO:0015853 adenine transport(GO:0015853)
0.0 0.4 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0090381 negative regulation of mesodermal cell fate specification(GO:0042662) motor learning(GO:0061743) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.9 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.0 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:0035900 response to isolation stress(GO:0035900)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.4 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 1.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 2.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0007398 ectoderm development(GO:0007398)
0.0 0.2 GO:1900120 regulation of receptor binding(GO:1900120)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.0 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.0 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 0.0 GO:1903423 synaptic vesicle recycling via endosome(GO:0036466) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) positive regulation of synaptic vesicle exocytosis(GO:2000302)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 14.8 GO:0000786 nucleosome(GO:0000786)
0.2 0.5 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2 0.6 GO:1990745 EARP complex(GO:1990745)
0.1 1.1 GO:0035976 AP1 complex(GO:0035976)
0.1 0.7 GO:0043196 varicosity(GO:0043196)
0.1 2.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.5 GO:0031906 late endosome lumen(GO:0031906)
0.1 0.3 GO:0005584 collagen type I trimer(GO:0005584)
0.1 1.1 GO:0045179 apical cortex(GO:0045179)
0.1 4.2 GO:0045095 keratin filament(GO:0045095)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.1 3.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 1.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 1.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.7 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252) pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.3 2.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 0.7 GO:0035033 histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 1.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.2 1.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 0.7 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2 0.5 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.6 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.4 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808)
0.1 0.4 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.7 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.9 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0031403 lithium ion binding(GO:0031403)
0.1 0.3 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.1 0.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0045569 TRAIL binding(GO:0045569)
0.1 1.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 3.1 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.2 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.2 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 1.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 1.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.2 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 3.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 7.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0051400 BH domain binding(GO:0051400)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 3.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 28.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 7.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 1.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions