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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for TAF1
Z-value: 2.62
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Transcription factors associated with TAF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TAF1 | hg19_v2_chrX_+_70586082_70586114 | 0.91 | 8.7e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of TAF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.5 | GO:1902100 | negative regulation of mitotic metaphase/anaphase transition(GO:0045841) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100) |
| 0.0 | 3.5 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.0 | 3.3 | GO:0000375 | RNA splicing, via transesterification reactions(GO:0000375) |
| 0.1 | 2.9 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.1 | 2.7 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 2.6 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.3 | 2.3 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.2 | 2.2 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 2.2 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 2.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.2 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.6 | 4.2 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.2 | 4.1 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.0 | 3.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 3.6 | GO:0001726 | ruffle(GO:0001726) |
| 0.3 | 2.8 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 2.8 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.0 | 2.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.3 | 2.5 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.1 | 2.3 | GO:0016580 | Sin3 complex(GO:0016580) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.9 | GO:0005525 | GTP binding(GO:0005525) |
| 0.1 | 5.5 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 5.4 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 5.1 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.0 | 4.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 4.0 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 3.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 3.1 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 2.7 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 2.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.9 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 5.0 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 4.5 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 4.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 4.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 3.7 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 3.6 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 3.2 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 2.3 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 2.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.7 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 4.8 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.0 | 4.7 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 4.2 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 3.4 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 3.2 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.1 | 3.2 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 2.8 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 2.4 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 2.3 | REACTOME KINESINS | Genes involved in Kinesins |