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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for STAT5A

Z-value: 1.01

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Transcription factors associated with STAT5A

Gene Symbol Gene ID Gene Info
ENSG00000126561.12 signal transducer and activator of transcription 5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40440094_40440190-0.831.7e-01Click!

Activity profile of STAT5A motif

Sorted Z-values of STAT5A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_50649192 0.48 ENST00000443053.2
ENST00000348721.3
cytokine inducible SH2-containing protein
chrX_+_106045891 0.47 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1 domain family, member 8B (with GRAM domain)
chr4_+_108815402 0.43 ENST00000503385.1
sphingomyelin synthase 2
chr7_+_142829162 0.37 ENST00000291009.3
prolactin-induced protein
chr1_-_42630389 0.36 ENST00000357001.2
guanylate cyclase activator 2A (guanylin)
chr1_-_17380630 0.36 ENST00000375499.3
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr10_-_5652705 0.35 ENST00000425246.1
RP11-336A10.5
chr17_-_34207295 0.32 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr12_-_21910775 0.32 ENST00000539782.1
lactate dehydrogenase B
chr18_-_66382289 0.31 ENST00000443099.2
ENST00000562706.1
ENST00000544714.2
thioredoxin-related transmembrane protein 3
chr19_+_35773242 0.30 ENST00000222304.3
hepcidin antimicrobial peptide
chr5_+_667759 0.29 ENST00000594226.1
Uncharacterized protein
chr4_+_130017268 0.28 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr19_+_58193388 0.28 ENST00000596085.1
ENST00000594684.1
zinc finger protein 551
Uncharacterized protein
chrX_-_139866723 0.28 ENST00000370532.2
cerebellar degeneration-related protein 1, 34kDa
chr3_-_71777824 0.27 ENST00000469524.1
eukaryotic translation initiation factor 4E family member 3
chr6_+_168434678 0.26 ENST00000496008.1
kinesin family member 25
chr15_+_63414760 0.26 ENST00000557972.1
lactamase, beta
chr4_-_6694189 0.26 ENST00000596858.1
Uncharacterized protein
chr2_+_90458201 0.26 ENST00000603238.1
Uncharacterized protein
chr11_+_36616355 0.25 ENST00000532470.2
chromosome 11 open reading frame 74
chr3_+_45430105 0.24 ENST00000430399.1
leucyl-tRNA synthetase 2, mitochondrial
chr4_+_38511367 0.24 ENST00000507056.1
RP11-213G21.1
chr10_+_71444655 0.23 ENST00000434931.2
Uncharacterized protein
chr12_+_133657461 0.23 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
zinc finger protein 140
chr11_+_121163466 0.23 ENST00000527762.1
ENST00000534230.1
ENST00000392789.2
sterol-C5-desaturase
chr15_-_78526942 0.22 ENST00000258873.4
acyl-CoA synthetase bubblegum family member 1
chr2_-_133104839 0.22 ENST00000608279.1
RP11-725P16.2
chr21_-_16125773 0.22 ENST00000454128.2
AF127936.3
chr12_+_79357815 0.22 ENST00000547046.1
synaptotagmin I
chr9_+_86237963 0.22 ENST00000277124.8
idnK, gluconokinase homolog (E. coli)
chr4_-_186125077 0.22 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
chr7_+_30589829 0.22 ENST00000579437.1
RP4-777O23.1
chr6_-_18264706 0.21 ENST00000244776.7
ENST00000503715.1
DEK oncogene
chr4_-_83933999 0.21 ENST00000510557.1
lin-54 homolog (C. elegans)
chr5_+_32585605 0.21 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1 homolog (S. cerevisiae)
chr22_-_28316116 0.21 ENST00000415296.1
phosphatidylinositol transfer protein, beta
chr3_+_160117418 0.21 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
structural maintenance of chromosomes 4
chr1_+_38478432 0.21 ENST00000537711.1
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr19_-_51875894 0.21 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr1_+_46769303 0.21 ENST00000311672.5
ubiquinol-cytochrome c reductase hinge protein
chr11_-_82997420 0.21 ENST00000455220.2
ENST00000529689.1
coiled-coil domain containing 90B
chr12_-_56211485 0.21 ENST00000552080.1
ENST00000444631.2
ENST00000336133.3
SAP domain containing ribonucleoprotein
chr19_+_37960240 0.20 ENST00000388801.3
zinc finger protein 570
chr2_-_68290106 0.20 ENST00000407324.1
ENST00000355848.3
ENST00000409302.1
ENST00000410067.3
C1D nuclear receptor corepressor
chr20_+_18447771 0.20 ENST00000377603.4
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr19_+_44507091 0.20 ENST00000429154.2
ENST00000585632.1
zinc finger protein 230
chr10_-_6622201 0.20 ENST00000539722.1
ENST00000397176.2
protein kinase C, theta
chr12_+_133614062 0.20 ENST00000540031.1
ENST00000536123.1
zinc finger protein 84
chr11_+_65779283 0.20 ENST00000312134.2
cystatin E/M
chr1_-_11107280 0.20 ENST00000400897.3
ENST00000400898.3
mannan-binding lectin serine peptidase 2
chr2_+_163200848 0.19 ENST00000233612.4
grancalcin, EF-hand calcium binding protein
chr10_-_33625154 0.19 ENST00000265371.4
neuropilin 1
chr5_-_118324200 0.19 ENST00000515439.3
ENST00000510708.1
DTW domain containing 2
chr19_+_35168567 0.19 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
zinc finger protein 302
chr5_-_34043310 0.19 ENST00000231338.7
C1q and tumor necrosis factor related protein 3
chr21_-_16126181 0.19 ENST00000455253.2
AF127936.3
chr4_+_87928353 0.19 ENST00000511722.1
AF4/FMR2 family, member 1
chr8_+_96037255 0.19 ENST00000286687.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr19_-_58485895 0.19 ENST00000314391.3
chromosome 19 open reading frame 18
chr19_-_8567505 0.19 ENST00000600262.1
PML-RARA regulated adaptor molecule 1
chr7_-_132766818 0.19 ENST00000262570.5
coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_+_147830362 0.19 ENST00000566741.1
sterile alpha motif domain containing 5
chr6_+_31633902 0.19 ENST00000375865.2
ENST00000375866.2
casein kinase 2, beta polypeptide
chr10_+_90660832 0.18 ENST00000371924.1
STAM binding protein-like 1
chr19_+_58193337 0.18 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
zinc finger protein 551
chr16_-_15463926 0.18 ENST00000432570.2
nuclear pore complex interacting protein family, member A5
chr12_+_133656995 0.18 ENST00000356456.5
zinc finger protein 140
chr2_-_55237484 0.18 ENST00000394609.2
reticulon 4
chr18_+_44526744 0.18 ENST00000585469.1
katanin p60 subunit A-like 2
chr19_+_40503013 0.18 ENST00000595225.1
zinc finger protein 546
chr10_+_112327425 0.18 ENST00000361804.4
structural maintenance of chromosomes 3
chr10_+_26986582 0.18 ENST00000376215.5
ENST00000376203.5
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr16_-_18418092 0.18 ENST00000545050.1
nuclear pore complex interacting protein family, member A8
chr17_+_9479944 0.18 ENST00000396219.3
ENST00000352665.5
WD repeat domain 16
chr11_+_36616044 0.18 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
chromosome 11 open reading frame 74
chr17_-_64216748 0.18 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr6_+_139349817 0.18 ENST00000367660.3
ABRA C-terminal like
chr4_-_165305086 0.18 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr19_-_4717835 0.18 ENST00000599248.1
dipeptidyl-peptidase 9
chr14_-_100841794 0.18 ENST00000556295.1
ENST00000554820.1
tryptophanyl-tRNA synthetase
chr7_+_7606639 0.18 ENST00000433056.1
missing oocyte, meiosis regulator, homolog (Drosophila)
chr2_-_264024 0.18 ENST00000403712.2
ENST00000356150.5
ENST00000405430.1
SH3 and SYLF domain containing 1
chr4_+_155484103 0.18 ENST00000302068.4
fibrinogen beta chain
chr3_-_160116995 0.17 ENST00000465537.1
ENST00000486856.1
ENST00000468218.1
ENST00000478370.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr2_+_85132749 0.17 ENST00000233143.4
thymosin beta 10
chr1_+_35247859 0.17 ENST00000373362.3
gap junction protein, beta 3, 31kDa
chr1_+_26503894 0.17 ENST00000361530.6
ENST00000374253.5
connector enhancer of kinase suppressor of Ras 1
chr19_+_35168633 0.17 ENST00000505365.2
zinc finger protein 302
chr10_+_27793257 0.17 ENST00000375802.3
RAB18, member RAS oncogene family
chr19_+_35225060 0.17 ENST00000599244.1
ENST00000392232.3
zinc finger protein 181
chr5_-_95550754 0.17 ENST00000502437.1
RP11-254I22.3
chr11_+_114271367 0.17 ENST00000544582.1
ENST00000545678.1
RNA binding motif protein 7
chr3_-_93747425 0.17 ENST00000315099.2
syntaxin 19
chr2_+_37423618 0.17 ENST00000402297.1
ENST00000397064.2
ENST00000406711.1
ENST00000392061.2
ENST00000397226.2
CEBPZ antisense RNA 1
chr14_+_56127960 0.17 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr8_+_124194875 0.17 ENST00000522648.1
ENST00000276699.6
family with sequence similarity 83, member A
chr20_+_2795626 0.17 ENST00000603872.1
ENST00000380589.4
chromosome 20 open reading frame 141
chr14_+_97263641 0.17 ENST00000216639.3
vaccinia related kinase 1
chr7_+_110731062 0.17 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr4_+_81118647 0.17 ENST00000415738.2
PR domain containing 8
chr10_-_6019455 0.17 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
interleukin 15 receptor, alpha
chr22_-_32589466 0.17 ENST00000248980.4
ret finger protein-like 2
chr6_-_18265050 0.17 ENST00000397239.3
DEK oncogene
chr19_+_17326521 0.16 ENST00000593597.1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr4_-_185776854 0.16 ENST00000511703.1
RP11-701P16.5
chr17_+_32582293 0.16 ENST00000580907.1
ENST00000225831.4
chemokine (C-C motif) ligand 2
chr6_+_84222220 0.16 ENST00000369700.3
protease, serine, 35
chr2_-_10830093 0.16 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
nucleolar protein 10
chr6_-_149867122 0.16 ENST00000253329.2
peptidylprolyl isomerase (cyclophilin)-like 4
chr2_+_70121075 0.16 ENST00000409116.1
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr16_-_3493528 0.16 ENST00000301744.4
zinc finger protein 597
chr5_+_111496631 0.16 ENST00000508590.1
EPB41L4A antisense RNA 1
chr10_+_72194585 0.16 ENST00000420338.2
Uncharacterized protein
chr2_-_17935027 0.16 ENST00000446852.1
structural maintenance of chromosomes 6
chr5_+_178450753 0.16 ENST00000444149.2
ENST00000519896.1
ENST00000522442.1
zinc finger protein 879
chr11_+_73498898 0.16 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
mitochondrial ribosomal protein L48
chr8_+_86157699 0.16 ENST00000321764.3
carbonic anhydrase XIII
chr1_+_45140400 0.16 ENST00000453711.1
chromosome 1 open reading frame 228
chrX_+_122993657 0.16 ENST00000434753.3
ENST00000430625.1
X-linked inhibitor of apoptosis
chr8_+_92082424 0.16 ENST00000285420.4
ENST00000404789.3
OTU domain containing 6B
chr4_+_142557771 0.16 ENST00000514653.1
interleukin 15
chr3_+_122296465 0.16 ENST00000483793.1
poly (ADP-ribose) polymerase family, member 15
chr3_-_160117301 0.16 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr3_+_13978886 0.16 ENST00000524375.1
ENST00000326972.8
tetra-peptide repeat homeobox-like
chr2_+_33701684 0.16 ENST00000442390.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr9_-_94877658 0.16 ENST00000262554.2
ENST00000337841.4
serine palmitoyltransferase, long chain base subunit 1
chr10_+_26727125 0.16 ENST00000376236.4
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr19_+_52430688 0.16 ENST00000391794.4
ENST00000599683.1
ENST00000600853.1
zinc finger protein 613
chr1_-_48937838 0.16 ENST00000371847.3
spermatogenesis associated 6
chr16_-_18462221 0.15 ENST00000528301.1
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr18_+_11751466 0.15 ENST00000535121.1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_+_73498973 0.15 ENST00000537007.1
mitochondrial ribosomal protein L48
chr14_-_100841930 0.15 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
tryptophanyl-tRNA synthetase
chr12_+_51347705 0.15 ENST00000398455.3
HIG1 hypoxia inducible domain family, member 1C
chr15_+_63414017 0.15 ENST00000413507.2
lactamase, beta
chr11_-_67373435 0.15 ENST00000446232.1
chromosome 11 open reading frame 72
chr15_-_83378611 0.15 ENST00000542200.1
adaptor-related protein complex 3, beta 2 subunit
chr18_+_61144160 0.15 ENST00000489441.1
ENST00000424602.1
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr8_-_112248400 0.15 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
chr20_+_1115821 0.15 ENST00000435720.1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chrX_-_19140677 0.15 ENST00000357544.3
ENST00000379869.3
ENST00000360279.4
ENST00000379873.2
ENST00000379878.3
ENST00000354791.3
ENST00000379876.1
G protein-coupled receptor 64
chr10_+_21823079 0.15 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr12_-_46384334 0.15 ENST00000369367.3
ENST00000266589.6
ENST00000395453.2
ENST00000395454.2
SR-related CTD-associated factor 11
chr12_-_104531945 0.15 ENST00000551446.1
nuclear transcription factor Y, beta
chr1_-_25558963 0.15 ENST00000354361.3
SYF2 pre-mRNA-splicing factor
chr17_-_76274572 0.15 ENST00000374945.1
RP11-219G17.4
chr20_+_2795609 0.15 ENST00000554164.1
ENST00000380593.4
transmembrane protein 239
CDNA FLJ26142 fis, clone TST04526; Transmembrane protein 239; Uncharacterized protein
chr3_+_160117087 0.15 ENST00000357388.3
structural maintenance of chromosomes 4
chr1_+_38478378 0.15 ENST00000373014.4
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr17_-_1463095 0.15 ENST00000575895.1
ENST00000573056.1
phosphatidylinositol transfer protein, alpha
chr13_+_115079949 0.15 ENST00000361283.1
chromosome alignment maintaining phosphoprotein 1
chr9_-_15510989 0.15 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PC4 and SFRS1 interacting protein 1
chr19_+_37498759 0.15 ENST00000590332.1
ENST00000587029.1
zinc finger protein 420
chr6_-_31689456 0.15 ENST00000495859.1
ENST00000375819.2
lymphocyte antigen 6 complex, locus G6C
chr18_-_68004529 0.15 ENST00000578633.1
RP11-484N16.1
chr3_-_4927447 0.15 ENST00000449914.1
Uncharacterized protein
chr8_-_30670053 0.14 ENST00000518564.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr17_-_4448361 0.14 ENST00000572759.1
MYB binding protein (P160) 1a
chr4_+_25378826 0.14 ENST00000315368.3
anaphase promoting complex subunit 4
chr10_+_27793197 0.14 ENST00000356940.6
ENST00000535776.1
RAB18, member RAS oncogene family
chr22_-_32767017 0.14 ENST00000400234.1
RFPL3 antisense
chr7_-_130597935 0.14 ENST00000447307.1
ENST00000418546.1
microRNA 29a
chr17_-_6543973 0.14 ENST00000571642.1
ENST00000572370.1
KIAA0753
chr12_+_44152740 0.14 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
interleukin-1 receptor-associated kinase 4
chr12_+_69080734 0.14 ENST00000378905.2
nucleoporin 107kDa
chr18_-_74839891 0.14 ENST00000581878.1
myelin basic protein
chrX_-_106146547 0.14 ENST00000276173.4
ENST00000411805.1
ripply transcriptional repressor 1
chr3_+_13978873 0.14 ENST00000530586.1
tetra-peptide repeat homeobox-like
chr14_-_21979428 0.14 ENST00000538267.1
ENST00000298717.4
methyltransferase like 3
chr16_+_31885079 0.14 ENST00000300870.10
ENST00000394846.3
zinc finger protein 267
chr3_-_107941230 0.14 ENST00000264538.3
intraflagellar transport 57 homolog (Chlamydomonas)
chr7_-_95225768 0.14 ENST00000005178.5
pyruvate dehydrogenase kinase, isozyme 4
chr10_+_104629199 0.14 ENST00000369880.3
arsenic (+3 oxidation state) methyltransferase
chr14_-_24898731 0.14 ENST00000267406.6
cerebellin 3 precursor
chr20_+_39657454 0.14 ENST00000361337.2
topoisomerase (DNA) I
chr1_-_94374946 0.14 ENST00000370238.3
glutamate-cysteine ligase, modifier subunit
chr19_+_35168547 0.14 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
zinc finger protein 302
chr2_+_29001711 0.14 ENST00000418910.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr12_+_133613937 0.14 ENST00000539354.1
ENST00000542874.1
ENST00000438628.2
zinc finger protein 84
chr9_-_140142222 0.14 ENST00000344774.4
ENST00000388932.2
family with sequence similarity 166, member A
chr8_-_23712312 0.14 ENST00000290271.2
stanniocalcin 1
chr18_+_66382428 0.14 ENST00000578970.1
ENST00000582371.1
ENST00000584775.1
coiled-coil domain containing 102B
chr19_-_44860820 0.14 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
zinc finger protein 112
chr12_+_20963647 0.13 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr4_+_54243917 0.13 ENST00000507166.1
factor interacting with PAPOLA and CPSF1
chr3_-_145940126 0.13 ENST00000498625.1
phospholipid scramblase 4
chr1_+_91966384 0.13 ENST00000430031.2
ENST00000234626.6
cell division cycle 7
chr19_+_30414551 0.13 ENST00000360605.4
ENST00000570564.1
ENST00000574233.1
ENST00000585655.1
URI1, prefoldin-like chaperone
chr8_+_109455845 0.13 ENST00000220853.3
ER membrane protein complex subunit 2
chr17_+_57784826 0.13 ENST00000262291.4
vacuole membrane protein 1
chr21_+_34602680 0.13 ENST00000447980.1
interferon (alpha, beta and omega) receptor 2
chr14_-_68162464 0.13 ENST00000553384.1
ENST00000557726.1
ENST00000381346.4
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr5_+_33441053 0.13 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
threonyl-tRNA synthetase
chr8_-_123139423 0.13 ENST00000523792.1
RP11-398G24.2
chr7_-_76247617 0.13 ENST00000441393.1
POM121 and ZP3 fusion
chr2_-_17935059 0.13 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
structural maintenance of chromosomes 6
chr10_-_9801179 0.13 ENST00000419836.1
RP5-1051H14.2
chr1_+_218458625 0.13 ENST00000366932.3
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr3_+_57882061 0.13 ENST00000461354.1
ENST00000466255.1
sarcolemma associated protein

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:1903413 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.3 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.1 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.2 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.2 GO:2000570 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.0 GO:0035378 carbon dioxide transport(GO:0015670) carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0044147 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0060629 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0061741 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0035696 monocyte extravasation(GO:0035696) interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350) regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427) regulation of monocyte extravasation(GO:2000437)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.0 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.1 GO:0035377 transepithelial water transport(GO:0035377)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.4 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.2 GO:0090166 histone H3-S10 phosphorylation(GO:0043987) Golgi disassembly(GO:0090166)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:1902683 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0031346 positive regulation of cell projection organization(GO:0031346)
0.0 0.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.1 GO:2000504 negative regulation of Fas signaling pathway(GO:1902045) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.0 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747) regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.0 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.2 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.0 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0008355 olfactory learning(GO:0008355)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.0 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.0 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.0 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.0 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.3 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.1 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.2 GO:0070704 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.1 0.3 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.3 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.3 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.0 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.0 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha