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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for SPI1

Z-value: 0.60

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Transcription factors associated with SPI1

Gene Symbol Gene ID Gene Info
SPI1
ENSG00000066336.7 Spi-1 proto-oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPI1hg19_v2_chr11_-_47400062_47400077-0.861.4e-01Click!

Activity profile of SPI1 motif

Sorted Z-values of SPI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_75532373 0.37 ENST00000595757.1
AC022400.2
Uncharacterized protein; cDNA FLJ44715 fis, clone BRACE3021430
chr11_-_3862206 0.35 ENST00000351018.4
RHOG
ras homolog family member G
chr2_-_220408260 0.32 ENST00000373891.2
CHPF
chondroitin polymerizing factor
chr9_+_2017063 0.31 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_-_64385981 0.24 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr8_+_22438009 0.23 ENST00000409417.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr14_-_23284703 0.21 ENST00000555911.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_+_16083123 0.20 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chr11_-_3862059 0.20 ENST00000396978.1
RHOG
ras homolog family member G
chr14_-_23285069 0.20 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_-_79269067 0.19 ENST00000288439.5
ENST00000374759.3
SLC38A10
solute carrier family 38, member 10
chr1_+_16083098 0.19 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr17_-_19651598 0.19 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr16_-_30394143 0.18 ENST00000321367.3
ENST00000571393.1
SEPT1
septin 1
chr5_+_180650271 0.18 ENST00000351937.5
ENST00000315073.5
TRIM41
tripartite motif containing 41
chr1_+_38273419 0.18 ENST00000468084.1
C1orf122
chromosome 1 open reading frame 122
chr12_+_94071129 0.18 ENST00000552983.1
ENST00000332896.3
ENST00000552033.1
ENST00000548483.1
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr6_-_34524093 0.18 ENST00000544425.1
SPDEF
SAM pointed domain containing ETS transcription factor
chr2_-_153573965 0.17 ENST00000448428.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr9_+_140172200 0.17 ENST00000357503.2
TOR4A
torsin family 4, member A
chr1_-_151254362 0.17 ENST00000447795.2
RP11-126K1.2
Uncharacterized protein
chr7_-_75241096 0.17 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr19_+_39421556 0.16 ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr5_-_140053152 0.16 ENST00000542735.1
DND1
DND microRNA-mediated repression inhibitor 1
chr14_+_102276192 0.16 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr6_+_144980954 0.16 ENST00000367525.3
UTRN
utrophin
chr3_+_49027771 0.16 ENST00000475629.1
ENST00000444213.1
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr8_+_22437965 0.16 ENST00000409141.1
ENST00000265810.4
PDLIM2
PDZ and LIM domain 2 (mystique)
chr17_-_33415837 0.16 ENST00000414419.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr11_+_394145 0.15 ENST00000528036.1
PKP3
plakophilin 3
chr19_-_3557570 0.15 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr11_-_67120974 0.15 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr10_-_126849626 0.15 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr16_+_30205225 0.15 ENST00000345535.4
ENST00000251303.6
SLX1A
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
chr6_-_32143828 0.15 ENST00000412465.2
ENST00000375107.3
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr1_-_52520828 0.14 ENST00000610127.1
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr6_-_33168391 0.14 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr6_+_100054606 0.14 ENST00000369215.4
PRDM13
PR domain containing 13
chr6_-_32160622 0.14 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr16_-_31085514 0.14 ENST00000300849.4
ZNF668
zinc finger protein 668
chr17_-_8093471 0.14 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr16_+_29465822 0.14 ENST00000330181.5
ENST00000351581.4
SLX1B
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr19_+_41257084 0.14 ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr14_+_74004051 0.14 ENST00000557556.1
ACOT1
acyl-CoA thioesterase 1
chr6_-_33266687 0.13 ENST00000444031.2
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr17_+_74261277 0.13 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr1_+_16083154 0.13 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr17_+_45908974 0.13 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr16_+_31085714 0.13 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr14_-_23285011 0.13 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_+_84767289 0.13 ENST00000394834.3
ENST00000370669.1
SAMD13
sterile alpha motif domain containing 13
chr11_-_72433346 0.13 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_+_17530838 0.13 ENST00000528659.1
ENST00000392702.2
ENST00000529939.1
MVB12A
multivesicular body subunit 12A
chr7_-_5569588 0.13 ENST00000417101.1
ACTB
actin, beta
chr11_+_64879317 0.13 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2
transmembrane 7 superfamily member 2
chr16_+_67261008 0.13 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
TMEM208
transmembrane protein 208
chr16_-_88717482 0.13 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr3_+_50388126 0.12 ENST00000425346.1
ENST00000424512.1
ENST00000232508.5
ENST00000418577.1
ENST00000606589.1
CYB561D2
XXcos-LUCA11.5
cytochrome b561 family, member D2
Uncharacterized protein
chr16_-_2205352 0.12 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr15_-_55488817 0.12 ENST00000569386.1
RSL24D1
ribosomal L24 domain containing 1
chr2_+_239756671 0.12 ENST00000448943.2
TWIST2
twist family bHLH transcription factor 2
chr17_-_7760457 0.12 ENST00000576384.1
LSMD1
LSM domain containing 1
chr17_+_74261413 0.12 ENST00000587913.1
UBALD2
UBA-like domain containing 2
chr9_+_135037334 0.12 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2
netrin G2
chr1_+_198126209 0.12 ENST00000367383.1
NEK7
NIMA-related kinase 7
chr17_-_7761256 0.12 ENST00000575208.1
LSMD1
LSM domain containing 1
chr20_+_62711482 0.12 ENST00000336866.2
ENST00000355631.4
OPRL1
opiate receptor-like 1
chr6_-_154751629 0.12 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr6_-_33267101 0.12 ENST00000497454.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr17_-_4710288 0.12 ENST00000571067.1
RP11-81A22.5
RP11-81A22.5
chr17_+_42422662 0.12 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN
granulin
chr1_+_31883048 0.11 ENST00000536859.1
SERINC2
serine incorporator 2
chr2_+_219262948 0.11 ENST00000443891.1
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr4_+_8201091 0.11 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr11_+_64073699 0.11 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr9_-_134145880 0.11 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr22_+_37678505 0.11 ENST00000402997.1
ENST00000405206.3
CYTH4
cytohesin 4
chr20_+_43990576 0.11 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr19_+_36236491 0.11 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr2_+_138721850 0.11 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr6_-_6320875 0.11 ENST00000451619.1
F13A1
coagulation factor XIII, A1 polypeptide
chr11_-_62358972 0.11 ENST00000278279.3
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr2_+_220094657 0.11 ENST00000436226.1
ANKZF1
ankyrin repeat and zinc finger domain containing 1
chr1_+_221051699 0.11 ENST00000366903.6
HLX
H2.0-like homeobox
chr11_+_66824346 0.11 ENST00000532559.1
RHOD
ras homolog family member D
chr4_+_926171 0.11 ENST00000507319.1
ENST00000264771.4
TMEM175
transmembrane protein 175
chr11_-_62359027 0.11 ENST00000494385.1
ENST00000308436.7
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr6_-_34524049 0.11 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chr17_-_43138463 0.11 ENST00000310604.4
DCAKD
dephospho-CoA kinase domain containing
chr11_+_66624527 0.11 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr19_+_15218180 0.11 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr16_-_67260901 0.11 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29
AC040160.1
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr3_+_181429704 0.10 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr4_-_140223614 0.10 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr16_-_67260691 0.10 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr19_-_12780211 0.10 ENST00000597961.1
ENST00000598732.1
ENST00000222190.5
CTD-2192J16.24
WDR83OS
Uncharacterized protein
WD repeat domain 83 opposite strand
chr14_-_77495007 0.10 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr11_-_118789613 0.10 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr8_+_99076750 0.10 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr11_+_45825616 0.10 ENST00000442528.2
ENST00000456334.1
ENST00000526817.1
SLC35C1
solute carrier family 35 (GDP-fucose transporter), member C1
chr8_-_144886321 0.10 ENST00000526832.1
SCRIB
scribbled planar cell polarity protein
chr6_-_113754604 0.10 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr4_-_153601136 0.10 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr19_+_35739897 0.10 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR
lipolysis stimulated lipoprotein receptor
chr4_+_926214 0.10 ENST00000514453.1
ENST00000515492.1
ENST00000509508.1
ENST00000515740.1
ENST00000508204.1
ENST00000510493.1
ENST00000514546.1
TMEM175
transmembrane protein 175
chr22_+_27068704 0.10 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5
CTA-211A9.5
chr3_-_178789220 0.10 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr11_+_128563652 0.10 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr17_-_6917755 0.09 ENST00000593646.1
AC040977.1
Uncharacterized protein
chr12_+_53443680 0.09 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr11_+_47430133 0.09 ENST00000531974.1
ENST00000531419.1
ENST00000531865.1
ENST00000362021.4
ENST00000354884.4
SLC39A13
solute carrier family 39 (zinc transporter), member 13
chr11_+_2421718 0.09 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4
tumor suppressing subtransferable candidate 4
chr21_+_33671264 0.09 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr11_-_62389449 0.09 ENST00000534026.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr11_-_62389621 0.09 ENST00000531383.1
ENST00000265471.5
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr7_+_150759634 0.09 ENST00000392826.2
ENST00000461735.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr12_-_118796910 0.09 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr11_+_64107663 0.09 ENST00000356786.5
CCDC88B
coiled-coil domain containing 88B
chr22_+_38004832 0.09 ENST00000405147.3
ENST00000429218.1
ENST00000325180.8
ENST00000337437.4
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr1_-_153917700 0.09 ENST00000368646.2
DENND4B
DENN/MADD domain containing 4B
chr12_-_58135903 0.09 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr11_+_844406 0.09 ENST00000397404.1
TSPAN4
tetraspanin 4
chr17_+_75315654 0.09 ENST00000590595.1
SEPT9
septin 9
chr2_+_32502952 0.09 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr12_-_56652111 0.09 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr3_-_11623804 0.09 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr2_+_28615669 0.09 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr17_+_38599693 0.09 ENST00000542955.1
ENST00000269593.4
IGFBP4
insulin-like growth factor binding protein 4
chr1_-_154909329 0.09 ENST00000368467.3
PMVK
phosphomevalonate kinase
chr19_+_14551066 0.08 ENST00000342216.4
PKN1
protein kinase N1
chr5_-_141060389 0.08 ENST00000504448.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_+_151254738 0.08 ENST00000336715.6
ENST00000324048.5
ENST00000368879.2
ZNF687
zinc finger protein 687
chr10_+_75532028 0.08 ENST00000372841.3
ENST00000394790.1
FUT11
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr15_-_55611306 0.08 ENST00000563262.1
RAB27A
RAB27A, member RAS oncogene family
chr17_+_65027509 0.08 ENST00000375684.1
AC005544.1
Uncharacterized protein
chr15_-_64386120 0.08 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr17_-_7760779 0.08 ENST00000335155.5
ENST00000575071.1
LSMD1
LSM domain containing 1
chr17_-_37844267 0.08 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
PGAP3
post-GPI attachment to proteins 3
chr11_+_120081475 0.08 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr17_+_49243639 0.08 ENST00000512737.1
ENST00000503064.1
NME1-NME2
NME1-NME2 readthrough
chr16_-_88717423 0.08 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr9_-_138987115 0.08 ENST00000277554.2
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr16_+_28875268 0.08 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr12_+_6493319 0.08 ENST00000536876.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr4_-_926069 0.08 ENST00000314167.4
ENST00000502656.1
GAK
cyclin G associated kinase
chr17_+_2264983 0.08 ENST00000574650.1
SGSM2
small G protein signaling modulator 2
chr17_+_4843352 0.08 ENST00000573404.1
ENST00000576452.1
RNF167
ring finger protein 167
chr9_+_139557360 0.08 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
EGFL7
EGF-like-domain, multiple 7
chr14_-_68157084 0.08 ENST00000557564.1
RP11-1012A1.4
RP11-1012A1.4
chr7_-_100076873 0.08 ENST00000300181.2
TSC22D4
TSC22 domain family, member 4
chr3_-_149293990 0.08 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr16_-_29875057 0.08 ENST00000219789.6
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr11_-_72432950 0.08 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr16_-_30393752 0.08 ENST00000566517.1
ENST00000605106.1
SEPT1
SEPT1
septin 1
Uncharacterized protein
chr14_+_65170820 0.08 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr14_+_65171099 0.08 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr17_+_7255208 0.08 ENST00000333751.3
KCTD11
potassium channel tetramerization domain containing 11
chr16_+_3162557 0.08 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
ZNF205
zinc finger protein 205
chr15_-_52971544 0.08 ENST00000566768.1
ENST00000561543.1
FAM214A
family with sequence similarity 214, member A
chr14_+_50159813 0.08 ENST00000359332.2
ENST00000553274.1
ENST00000557128.1
KLHDC1
kelch domain containing 1
chr16_+_28875126 0.08 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr6_-_33266492 0.07 ENST00000425946.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr12_-_92539614 0.07 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr17_-_40134339 0.07 ENST00000587727.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr14_+_24563510 0.07 ENST00000545054.2
ENST00000561286.1
ENST00000558096.1
PCK2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr16_-_28506840 0.07 ENST00000569430.1
CLN3
ceroid-lipofuscinosis, neuronal 3
chr16_-_68404908 0.07 ENST00000574662.1
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr14_+_23340822 0.07 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr19_-_4559814 0.07 ENST00000586582.1
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr14_-_50999373 0.07 ENST00000554273.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr17_-_43510282 0.07 ENST00000290470.3
ARHGAP27
Rho GTPase activating protein 27
chr3_-_187455680 0.07 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr18_-_60985914 0.07 ENST00000589955.1
BCL2
B-cell CLL/lymphoma 2
chr3_-_50360192 0.07 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
HYAL2
hyaluronoglucosaminidase 2
chr4_+_103422499 0.07 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr19_-_12792704 0.07 ENST00000210060.7
DHPS
deoxyhypusine synthase
chr22_-_39150947 0.07 ENST00000411587.2
ENST00000420859.1
ENST00000452294.1
ENST00000456894.1
SUN2
Sad1 and UNC84 domain containing 2
chr19_+_48248779 0.07 ENST00000246802.5
GLTSCR2
glioma tumor suppressor candidate region gene 2
chr3_+_9774164 0.07 ENST00000426583.1
BRPF1
bromodomain and PHD finger containing, 1
chr17_-_26697304 0.07 ENST00000536498.1
VTN
vitronectin
chr7_-_143579973 0.07 ENST00000460532.1
ENST00000491908.1
FAM115A
family with sequence similarity 115, member A
chrX_-_49056635 0.07 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
SYP
synaptophysin
chr6_+_33168597 0.07 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr2_+_220462560 0.07 ENST00000456909.1
ENST00000295641.10
STK11IP
serine/threonine kinase 11 interacting protein
chr19_+_42387228 0.07 ENST00000354532.3
ENST00000599846.1
ENST00000347545.4
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr11_-_6502534 0.07 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ARFIP2
ADP-ribosylation factor interacting protein 2
chr6_-_32145861 0.07 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr19_+_36119929 0.07 ENST00000588161.1
ENST00000262633.4
ENST00000592202.1
ENST00000586618.1
RBM42
RNA binding motif protein 42
chr16_+_20911174 0.07 ENST00000568663.1
LYRM1
LYR motif containing 1
chr8_-_121457608 0.07 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr18_+_21594384 0.07 ENST00000584250.1
TTC39C
tetratricopeptide repeat domain 39C
chr17_+_4843679 0.07 ENST00000576229.1
RNF167
ring finger protein 167
chr5_+_174151536 0.07 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr2_-_183291741 0.07 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr16_-_67597789 0.07 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr4_+_109571800 0.07 ENST00000512478.2
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr17_+_8191815 0.07 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr1_-_157108266 0.07 ENST00000326786.4
ETV3
ets variant 3
chr14_-_23451467 0.07 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
AJUBA
RP11-298I3.5
ajuba LIM protein
chr20_+_43374421 0.07 ENST00000372861.3
KCNK15
potassium channel, subfamily K, member 15

Network of associatons between targets according to the STRING database.

First level regulatory network of SPI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.2 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.3 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0060481 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.0 0.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.2 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.3 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.0 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.0 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.0 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.0 0.5 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.1 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.0 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.0 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.0 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.0 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0046930 pore complex(GO:0046930)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) corticotropin hormone receptor binding(GO:0031780) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.0 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0004974 leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.0 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.0 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.0 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR