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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for SOX30

Z-value: 0.55

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Transcription factors associated with SOX30

Gene Symbol Gene ID Gene Info
SOX30
ENSG00000039600.6 SRY-box transcription factor 30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX30hg19_v2_chr5_-_157079372_1570793950.683.2e-01Click!

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_11002063 0.24 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr22_+_31488433 0.19 ENST00000455608.1
SMTN
smoothelin
chr14_+_52456327 0.18 ENST00000556760.1
C14orf166
chromosome 14 open reading frame 166
chr11_-_85430088 0.15 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr14_+_52456193 0.14 ENST00000261700.3
C14orf166
chromosome 14 open reading frame 166
chr1_+_244998918 0.13 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr1_-_198906528 0.12 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr11_-_102323740 0.12 ENST00000398136.2
TMEM123
transmembrane protein 123
chr2_-_162931052 0.12 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr1_-_243418621 0.12 ENST00000366544.1
ENST00000366543.1
CEP170
centrosomal protein 170kDa
chr10_+_70480963 0.12 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1
cell division cycle and apoptosis regulator 1
chr1_-_243418344 0.12 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr1_+_228337553 0.12 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr11_-_102323489 0.12 ENST00000361236.3
TMEM123
transmembrane protein 123
chr11_-_85430204 0.11 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr11_-_85430163 0.11 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr2_-_37899323 0.09 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr1_+_185014496 0.09 ENST00000367510.3
RNF2
ring finger protein 2
chr12_-_49581152 0.09 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr5_+_179135246 0.09 ENST00000508787.1
CANX
calnexin
chr10_+_35416223 0.09 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr1_-_26231589 0.09 ENST00000374291.1
STMN1
stathmin 1
chr4_+_54243798 0.09 ENST00000337488.6
ENST00000358575.5
ENST00000507922.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr4_+_113152978 0.09 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr5_+_67588312 0.08 ENST00000519025.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_+_54243917 0.08 ENST00000507166.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr17_-_38821373 0.08 ENST00000394052.3
KRT222
keratin 222
chr4_+_54243862 0.07 ENST00000306932.6
FIP1L1
factor interacting with PAPOLA and CPSF1
chr3_-_165555200 0.07 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr5_+_139175380 0.07 ENST00000274710.3
PSD2
pleckstrin and Sec7 domain containing 2
chr12_+_95611536 0.07 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr4_-_69111401 0.07 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr14_-_36645674 0.07 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr6_-_128222103 0.06 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr11_+_125365110 0.06 ENST00000527818.1
AP000708.1
AP000708.1
chrX_+_102192200 0.06 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr10_+_35416090 0.06 ENST00000354759.3
CREM
cAMP responsive element modulator
chr12_+_95611516 0.06 ENST00000436874.1
VEZT
vezatin, adherens junctions transmembrane protein
chr9_-_134145880 0.06 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr1_-_243418650 0.06 ENST00000522995.1
CEP170
centrosomal protein 170kDa
chr12_+_95611569 0.06 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr10_+_35415851 0.06 ENST00000374726.3
CREM
cAMP responsive element modulator
chr13_+_98795664 0.06 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_-_18548426 0.06 ENST00000357193.3
ENST00000536719.1
TSG101
tumor susceptibility 101
chrX_-_15872914 0.05 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr21_+_35552978 0.05 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr17_-_73149921 0.05 ENST00000481647.1
ENST00000470924.1
HN1
hematological and neurological expressed 1
chr20_-_5426380 0.05 ENST00000609252.1
ENST00000422352.1
LINC00658
long intergenic non-protein coding RNA 658
chr17_+_47448102 0.05 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr9_-_85882145 0.05 ENST00000328788.1
FRMD3
FERM domain containing 3
chr3_-_19988462 0.05 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr16_+_4545853 0.05 ENST00000575129.1
ENST00000398595.3
ENST00000414777.1
HMOX2
heme oxygenase (decycling) 2
chr13_-_41593425 0.05 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_+_99953816 0.05 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr5_-_146461027 0.05 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr21_+_30671690 0.04 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr8_-_141810634 0.04 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr20_-_62610982 0.04 ENST00000369886.3
ENST00000450107.1
SAMD10
sterile alpha motif domain containing 10
chr5_+_65222438 0.04 ENST00000380938.2
ERBB2IP
erbb2 interacting protein
chr1_-_21503337 0.04 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr18_+_7946941 0.04 ENST00000444013.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr2_-_169769787 0.04 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr1_+_40942887 0.04 ENST00000372706.1
ZFP69
ZFP69 zinc finger protein
chr2_+_27719697 0.04 ENST00000264717.2
ENST00000424318.2
GCKR
glucokinase (hexokinase 4) regulator
chr7_-_82792215 0.04 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chrY_+_15016013 0.04 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr3_-_122283424 0.04 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr9_+_103235365 0.04 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr15_+_93426514 0.04 ENST00000556722.1
CHD2
chromodomain helicase DNA binding protein 2
chr22_+_46449674 0.04 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr6_-_11779014 0.04 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr20_-_45981138 0.04 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr2_-_157198860 0.03 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr17_+_67498538 0.03 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_-_85430356 0.03 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr6_-_11779174 0.03 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr14_+_36295504 0.03 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr2_+_86669118 0.03 ENST00000427678.1
ENST00000542128.1
KDM3A
lysine (K)-specific demethylase 3A
chr1_+_93913713 0.03 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr1_+_244998602 0.03 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr1_-_200379129 0.03 ENST00000367353.1
ZNF281
zinc finger protein 281
chr5_+_170288856 0.03 ENST00000523189.1
RANBP17
RAN binding protein 17
chr1_+_149239529 0.03 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr6_+_12290586 0.03 ENST00000379375.5
EDN1
endothelin 1
chr20_-_5426332 0.03 ENST00000420529.1
LINC00658
long intergenic non-protein coding RNA 658
chr12_-_99288986 0.03 ENST00000552407.1
ENST00000551613.1
ENST00000548447.1
ENST00000546364.3
ENST00000552748.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_74383302 0.03 ENST00000377066.5
TMEM2
transmembrane protein 2
chr21_+_35553045 0.03 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr5_+_135468516 0.03 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr15_+_57211318 0.03 ENST00000557947.1
TCF12
transcription factor 12
chr1_+_47489240 0.03 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr11_-_89224638 0.02 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr4_+_144303093 0.02 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr5_+_38148582 0.02 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr11_-_8964580 0.02 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr5_-_141338627 0.02 ENST00000231484.3
PCDH12
protocadherin 12
chr22_-_43485381 0.02 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
TTLL1
tubulin tyrosine ligase-like family, member 1
chr2_+_143635067 0.02 ENST00000264170.4
KYNU
kynureninase
chr6_+_126240442 0.02 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr6_+_22146851 0.02 ENST00000606197.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chrX_+_114874727 0.02 ENST00000543070.1
PLS3
plastin 3
chr3_-_8686479 0.02 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chrX_+_41192595 0.02 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr3_+_19988566 0.02 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr18_-_53804580 0.01 ENST00000590484.1
ENST00000589293.1
ENST00000587904.1
ENST00000591974.1
RP11-456O19.4
RP11-456O19.4
chr1_-_167883353 0.01 ENST00000545172.1
ADCY10
adenylate cyclase 10 (soluble)
chr2_-_166060382 0.01 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr5_-_59481406 0.01 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_134639180 0.01 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr22_-_30970498 0.01 ENST00000431313.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr4_+_187148556 0.01 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr2_+_232573208 0.01 ENST00000409115.3
PTMA
prothymosin, alpha
chr1_-_156828810 0.00 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr12_+_27623565 0.00 ENST00000535986.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr12_+_9066472 0.00 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr21_+_30672433 0.00 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr4_-_87028478 0.00 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr1_+_185703513 0.00 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr12_+_80750134 0.00 ENST00000546620.1
OTOGL
otogelin-like

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0036343 negative regulation of extracellular matrix disassembly(GO:0010716) psychomotor behavior(GO:0036343)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:2000395 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.0 GO:0006788 heme oxidation(GO:0006788)
0.0 0.0 GO:0051866 general adaptation syndrome(GO:0051866)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705)