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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for SOX21

Z-value: 0.24

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Transcription factors associated with SOX21

Gene Symbol Gene ID Gene Info
SOX21
ENSG00000125285.4 SRY-box transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX21hg19_v2_chr13_-_95364389_95364389-0.742.6e-01Click!

Activity profile of SOX21 motif

Sorted Z-values of SOX21 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_42381173 0.11 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr3_+_186288454 0.11 ENST00000265028.3
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr2_+_3705785 0.10 ENST00000252505.3
ALLC
allantoicase
chr19_-_2783255 0.10 ENST00000589251.1
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr11_+_35201826 0.09 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr14_+_64565442 0.09 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chr19_+_42381337 0.08 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr15_-_80263506 0.08 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr16_-_15149828 0.08 ENST00000566419.1
ENST00000568320.1
NTAN1
N-terminal asparagine amidase
chr10_-_12084770 0.07 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr4_-_103747011 0.07 ENST00000350435.7
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr22_+_39353527 0.07 ENST00000249116.2
APOBEC3A
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr6_+_31371337 0.07 ENST00000449934.2
ENST00000421350.1
MICA
MHC class I polypeptide-related sequence A
chrY_+_14813160 0.06 ENST00000338981.3
USP9Y
ubiquitin specific peptidase 9, Y-linked
chr5_+_67588312 0.06 ENST00000519025.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_134181755 0.06 ENST00000504727.1
ENST00000435259.2
ENST00000508791.1
C5orf24
chromosome 5 open reading frame 24
chr10_-_18944123 0.06 ENST00000606425.1
RP11-139J15.7
Uncharacterized protein
chr4_-_103746683 0.06 ENST00000504211.1
ENST00000508476.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_+_67687413 0.06 ENST00000521960.1
ENST00000522398.1
ENST00000522629.1
ENST00000520976.1
ENST00000396596.1
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr17_+_66245341 0.06 ENST00000577985.1
AMZ2
archaelysin family metallopeptidase 2
chr14_-_102771462 0.06 ENST00000522874.1
MOK
MOK protein kinase
chr4_-_103746924 0.06 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr14_-_92588013 0.06 ENST00000553514.1
ENST00000605997.1
NDUFB1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
chr8_+_26150628 0.05 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr4_-_83931862 0.05 ENST00000506560.1
ENST00000442461.2
ENST00000446851.2
ENST00000340417.3
LIN54
lin-54 homolog (C. elegans)
chr4_+_75174204 0.05 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN
epithelial mitogen
chr3_-_45957534 0.05 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr1_+_203764742 0.05 ENST00000432282.1
ENST00000453771.1
ENST00000367214.1
ENST00000367212.3
ENST00000332127.4
ZC3H11A
zinc finger CCCH-type containing 11A
chr8_+_101170563 0.05 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chr12_-_89746173 0.05 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr1_+_152881014 0.05 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr7_-_37382683 0.04 ENST00000455879.1
ELMO1
engulfment and cell motility 1
chr14_-_38028689 0.04 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr3_-_164875850 0.04 ENST00000472120.1
RP11-747D18.1
RP11-747D18.1
chr4_-_39034542 0.04 ENST00000344606.6
TMEM156
transmembrane protein 156
chr3_-_37034702 0.04 ENST00000322716.5
EPM2AIP1
EPM2A (laforin) interacting protein 1
chr8_-_143961236 0.04 ENST00000377675.3
ENST00000517471.1
ENST00000292427.4
CYP11B1
cytochrome P450, family 11, subfamily B, polypeptide 1
chr6_+_151815143 0.04 ENST00000239374.7
ENST00000367290.5
CCDC170
coiled-coil domain containing 170
chr3_-_45957088 0.04 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr19_-_2783363 0.03 ENST00000221566.2
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr6_-_121655593 0.03 ENST00000398212.2
TBC1D32
TBC1 domain family, member 32
chr1_-_202776392 0.03 ENST00000235790.4
KDM5B
lysine (K)-specific demethylase 5B
chr16_-_15982440 0.03 ENST00000575938.1
ENST00000573396.1
ENST00000573968.1
ENST00000575744.1
ENST00000573429.1
ENST00000255759.6
ENST00000575073.1
FOPNL
FGFR1OP N-terminal like
chr1_-_169455169 0.03 ENST00000367804.4
ENST00000236137.5
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr22_-_40929812 0.03 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr14_+_92588281 0.03 ENST00000298875.4
ENST00000553427.1
CPSF2
cleavage and polyadenylation specific factor 2, 100kDa
chr8_-_94029882 0.03 ENST00000520686.1
TRIQK
triple QxxK/R motif containing
chr12_+_101673872 0.02 ENST00000261637.4
UTP20
UTP20, small subunit (SSU) processome component, homolog (yeast)
chr12_+_123011776 0.02 ENST00000450485.2
ENST00000333479.7
KNTC1
kinetochore associated 1
chr1_-_54303934 0.02 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr14_-_92588246 0.02 ENST00000329559.3
NDUFB1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
chr14_+_50291993 0.02 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr6_-_121655850 0.02 ENST00000422369.1
TBC1D32
TBC1 domain family, member 32
chr11_+_2482661 0.02 ENST00000335475.5
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr3_+_141103634 0.02 ENST00000507722.1
ZBTB38
zinc finger and BTB domain containing 38
chr1_+_146714291 0.02 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L
chromodomain helicase DNA binding protein 1-like
chr3_-_141747459 0.02 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_-_154567984 0.02 ENST00000517438.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr7_-_14942944 0.02 ENST00000403951.2
DGKB
diacylglycerol kinase, beta 90kDa
chr11_+_114549108 0.02 ENST00000389586.4
ENST00000375475.5
NXPE2
neurexophilin and PC-esterase domain family, member 2
chr3_-_141747439 0.01 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr14_+_60712463 0.01 ENST00000325642.3
ENST00000529574.1
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_+_151171012 0.01 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr6_+_42531798 0.01 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr18_+_29769978 0.01 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr3_-_155572164 0.01 ENST00000392845.3
ENST00000359479.3
SLC33A1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr10_-_17243579 0.01 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
TRDMT1
tRNA aspartic acid methyltransferase 1
chr3_+_37035289 0.01 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
MLH1
mutL homolog 1
chr5_+_175875349 0.01 ENST00000261942.6
FAF2
Fas associated factor family member 2
chr12_-_1058849 0.01 ENST00000358495.3
RAD52
RAD52 homolog (S. cerevisiae)
chr18_-_47018897 0.01 ENST00000418495.1
RPL17
ribosomal protein L17
chr1_-_151148492 0.01 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chrX_-_55208866 0.01 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr10_-_71169031 0.01 ENST00000373307.1
TACR2
tachykinin receptor 2
chr5_-_179045199 0.01 ENST00000523921.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr19_+_18682531 0.01 ENST00000596304.1
ENST00000430157.2
UBA52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr7_+_2394445 0.01 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
EIF3B
eukaryotic translation initiation factor 3, subunit B
chr1_-_75100539 0.01 ENST00000420661.2
C1orf173
chromosome 1 open reading frame 173
chrX_-_131353461 0.01 ENST00000370874.1
RAP2C
RAP2C, member of RAS oncogene family
chr6_-_52926539 0.00 ENST00000350082.5
ENST00000356971.3
ICK
intestinal cell (MAK-like) kinase
chr4_-_69083720 0.00 ENST00000432593.3
TMPRSS11BNL
TMPRSS11B N-terminal like
chr1_+_158901329 0.00 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr3_+_37035263 0.00 ENST00000458205.2
ENST00000539477.1
MLH1
mutL homolog 1
chrY_+_16634483 0.00 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr4_-_177190364 0.00 ENST00000296525.3
ASB5
ankyrin repeat and SOCS box containing 5
chr12_-_1058685 0.00 ENST00000397230.2
ENST00000542785.1
ENST00000544742.1
ENST00000536177.1
ENST00000539046.1
ENST00000541619.1
RAD52
RAD52 homolog (S. cerevisiae)
chr12_-_10324716 0.00 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr21_+_30672433 0.00 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr5_-_95158644 0.00 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.0 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)