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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for SOX11

Z-value: 0.43

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Transcription factors associated with SOX11

Gene Symbol Gene ID Gene Info
ENSG00000176887.5 SRY-box transcription factor 11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX11hg19_v2_chr2_+_5832799_58327990.118.9e-01Click!

Activity profile of SOX11 motif

Sorted Z-values of SOX11 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39989535 0.22 ENST00000356433.5
delta-like 3 (Drosophila)
chr6_+_26183958 0.22 ENST00000356530.3
histone cluster 1, H2be
chr6_-_154751629 0.20 ENST00000424998.1
CNKSR family member 3
chr2_-_176046391 0.18 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr2_-_37068530 0.16 ENST00000593798.1
Uncharacterized protein
chr7_-_56118981 0.15 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
phosphoserine phosphatase
chr10_+_5238793 0.15 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr3_-_167191814 0.15 ENST00000466903.1
ENST00000264677.4
serpin peptidase inhibitor, clade I (pancpin), member 2
chr19_+_50094866 0.14 ENST00000418929.2
proline rich 12
chr16_+_67261008 0.14 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
transmembrane protein 208
chrM_+_8366 0.14 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr11_+_92085262 0.13 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr20_-_30539773 0.13 ENST00000202017.4
p53 and DNA-damage regulated 1
chr3_-_47950745 0.13 ENST00000429422.1
microtubule-associated protein 4
chr13_-_45048386 0.12 ENST00000472477.1
TSC22 domain family, member 1
chr17_+_6347761 0.12 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
family with sequence similarity 64, member A
chr4_-_105416039 0.12 ENST00000394767.2
CXXC finger protein 4
chr11_-_64684672 0.12 ENST00000377264.3
ENST00000421419.2
autophagy related 2A
chr3_-_49967292 0.12 ENST00000455683.2
MON1 secretory trafficking family member A
chr17_-_79895154 0.11 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
pyrroline-5-carboxylate reductase 1
chr15_-_36544450 0.11 ENST00000561394.1
RP11-184D12.1
chr12_+_70574088 0.11 ENST00000552324.1
RP11-320P7.2
chr7_-_143579973 0.11 ENST00000460532.1
ENST00000491908.1
family with sequence similarity 115, member A
chr17_-_79895097 0.10 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
pyrroline-5-carboxylate reductase 1
chr15_-_64673630 0.10 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr15_-_64673665 0.10 ENST00000300035.4
KIAA0101
chr6_+_30585486 0.10 ENST00000259873.4
ENST00000506373.2
mitochondrial ribosomal protein S18B
chr1_+_149754227 0.10 ENST00000444948.1
ENST00000369168.4
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr17_-_72772462 0.10 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr4_+_71019903 0.10 ENST00000344526.5
chromosome 4 open reading frame 40
chr11_-_62476694 0.10 ENST00000524862.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr2_-_37501692 0.09 ENST00000443977.1
protein kinase D3
chr12_-_11287243 0.09 ENST00000539585.1
taste receptor, type 2, member 30
chr8_-_37707356 0.09 ENST00000520601.1
ENST00000521170.1
ENST00000220659.6
BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
chr10_-_5446786 0.09 ENST00000479328.1
ENST00000380419.3
tubulin, alpha-like 3
chr20_-_32308028 0.09 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
peroxisomal membrane protein 4, 24kDa
chrX_-_7895755 0.08 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr6_-_31125850 0.08 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
coiled-coil alpha-helical rod protein 1
chr4_+_57276661 0.08 ENST00000598320.1
Uncharacterized protein
chr3_+_112930373 0.08 ENST00000498710.1
BOC cell adhesion associated, oncogene regulated
chr1_+_149239529 0.08 ENST00000457216.2
RP11-403I13.4
chr21_+_43619796 0.08 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr2_+_105050794 0.08 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr17_+_6347729 0.08 ENST00000572447.1
family with sequence similarity 64, member A
chr3_+_112930387 0.07 ENST00000485230.1
BOC cell adhesion associated, oncogene regulated
chr5_+_140213815 0.07 ENST00000525929.1
ENST00000378125.3
protocadherin alpha 7
chr5_+_175085033 0.07 ENST00000377291.2
histamine receptor H2
chr2_-_190044480 0.07 ENST00000374866.3
collagen, type V, alpha 2
chr17_+_38474489 0.07 ENST00000394089.2
ENST00000425707.3
retinoic acid receptor, alpha
chr6_+_131958436 0.07 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr6_-_170893268 0.06 ENST00000538195.1
programmed cell death 2
chr1_-_219615984 0.06 ENST00000420762.1
RP11-95P13.1
chr15_+_99433570 0.06 ENST00000558898.1
insulin-like growth factor 1 receptor
chrX_-_109590174 0.06 ENST00000372054.1
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr2_+_42104692 0.06 ENST00000398796.2
ENST00000442214.1
AC104654.1
chr2_-_219157250 0.06 ENST00000434015.2
ENST00000444183.1
ENST00000420341.1
ENST00000453281.1
ENST00000258412.3
ENST00000440422.1
transmembrane BAX inhibitor motif containing 1
chr17_+_61151306 0.06 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr4_-_159080806 0.06 ENST00000590648.1
family with sequence similarity 198, member B
chr9_+_12775011 0.06 ENST00000319264.3
leucine rich adaptor protein 1-like
chr7_+_90032821 0.05 ENST00000427904.1
claudin 12
chr14_+_21156915 0.05 ENST00000397990.4
ENST00000555597.1
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr12_-_122240792 0.05 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
ras homolog family member F (in filopodia)
chr2_+_166326157 0.05 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
cysteine-serine-rich nuclear protein 3
chr4_+_144312659 0.05 ENST00000509992.1
GRB2-associated binding protein 1
chr21_+_17792672 0.05 ENST00000602620.1
long intergenic non-protein coding RNA 478
chr1_-_205744574 0.05 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7, member RAS oncogene family-like 1
chr1_+_196621156 0.05 ENST00000359637.2
complement factor H
chr8_-_623547 0.05 ENST00000522893.1
glutamate-rich 1
chr2_+_138722028 0.05 ENST00000280096.5
histamine N-methyltransferase
chr8_-_128960591 0.05 ENST00000539634.1
transmembrane protein 75
chr17_-_66951474 0.05 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr8_-_25281747 0.05 ENST00000421054.2
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr15_+_45028719 0.04 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
tripartite motif containing 69
chr5_+_140248518 0.04 ENST00000398640.2
protocadherin alpha 11
chr4_-_90759440 0.04 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr11_-_58611957 0.04 ENST00000532258.1
glycine-N-acyltransferase-like 2
chr17_+_47448102 0.04 ENST00000576461.1
Uncharacterized protein
chr2_-_71222466 0.04 ENST00000606025.1
Uncharacterized protein
chr2_+_207804278 0.04 ENST00000272852.3
carboxypeptidase O
chr7_-_92855762 0.04 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chr4_+_72204755 0.04 ENST00000512686.1
ENST00000340595.3
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chrX_+_107288197 0.03 ENST00000415430.3
V-set and immunoglobulin domain containing 1
chr18_+_46065393 0.03 ENST00000256413.3
CBP80/20-dependent translation initiation factor
chr1_+_146373546 0.03 ENST00000446760.2
neuroblastoma breakpoint family, member 12
chr22_+_24407776 0.03 ENST00000405822.2
calcineurin binding protein 1
chr19_-_5680499 0.03 ENST00000587589.1
chromosome 19 open reading frame 70
chr14_+_39703112 0.03 ENST00000555143.1
ENST00000280082.3
melanoma inhibitory activity 2
chr1_+_196621002 0.03 ENST00000367429.4
ENST00000439155.2
complement factor H
chr3_-_112564797 0.03 ENST00000398214.1
ENST00000448932.1
CD200 receptor 1-like
chr5_+_140207536 0.03 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr17_-_66951382 0.03 ENST00000586539.1
ATP-binding cassette, sub-family A (ABC1), member 8
chr2_+_138721850 0.03 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr13_+_76413852 0.03 ENST00000533809.2
LIM domain 7
chr5_-_115872124 0.03 ENST00000515009.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_+_102192200 0.03 ENST00000218249.5
RAB40A, member RAS oncogene family-like
chrX_+_107288239 0.03 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr4_-_186570679 0.02 ENST00000451974.1
sorbin and SH3 domain containing 2
chr2_+_27799389 0.02 ENST00000408964.2
chromosome 2 open reading frame 16
chr15_+_80733570 0.02 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
aryl-hydrocarbon receptor nuclear translocator 2
chr13_-_30424821 0.02 ENST00000380680.4
ubiquitin-like 3
chr12_-_22063787 0.02 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr5_+_140753444 0.02 ENST00000517434.1
protocadherin gamma subfamily A, 6
chr3_+_113251143 0.02 ENST00000264852.4
ENST00000393830.3
SID1 transmembrane family, member 1
chr18_+_46065483 0.02 ENST00000382998.4
CBP80/20-dependent translation initiation factor
chr9_+_75766763 0.02 ENST00000456643.1
ENST00000415424.1
annexin A1
chr3_-_87325728 0.02 ENST00000350375.2
POU class 1 homeobox 1
chr10_+_32873190 0.02 ENST00000375025.4
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr1_-_205744205 0.02 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr7_+_98923505 0.02 ENST00000432884.2
ENST00000262942.5
actin related protein 2/3 complex, subunit 1A, 41kDa
chr4_-_110624564 0.02 ENST00000352981.3
ENST00000265164.2
ENST00000505486.1
caspase 6, apoptosis-related cysteine peptidase
chr8_+_104831472 0.02 ENST00000262231.10
ENST00000507740.1
regulating synaptic membrane exocytosis 2
chr19_-_6501778 0.02 ENST00000596291.1
tubulin, beta 4A class IVa
chr3_-_18466026 0.02 ENST00000417717.2
SATB homeobox 1
chr3_+_101504200 0.02 ENST00000422132.1
neurexophilin and PC-esterase domain family, member 3
chr6_-_56492816 0.02 ENST00000522360.1
dystonin
chr5_-_115872142 0.02 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_-_100548045 0.02 ENST00000372907.3
ENST00000372905.2
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr15_-_78913628 0.02 ENST00000348639.3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr9_-_95166841 0.02 ENST00000262551.4
osteoglycin
chr17_+_35732916 0.02 ENST00000586700.1
chromosome 17 open reading frame 78
chr3_+_112930306 0.02 ENST00000495514.1
BOC cell adhesion associated, oncogene regulated
chr12_+_56075330 0.02 ENST00000394252.3
methyltransferase like 7B
chr17_-_10276319 0.01 ENST00000252172.4
ENST00000418404.3
myosin, heavy chain 13, skeletal muscle
chr6_-_11779014 0.01 ENST00000229583.5
androgen-dependent TFPI-regulating protein
chr7_-_7575477 0.01 ENST00000399429.3
collagen, type XXVIII, alpha 1
chr7_+_90012986 0.01 ENST00000416322.1
claudin 12
chr11_+_22688150 0.01 ENST00000454584.2
growth arrest-specific 2
chr1_+_198608146 0.01 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr10_+_69865866 0.01 ENST00000354393.2
myopalladin
chr5_+_40841410 0.01 ENST00000381677.3
caspase recruitment domain family, member 6
chr17_-_72772425 0.01 ENST00000578822.1
N-acetyltransferase 9 (GCN5-related, putative)
chr10_-_127505167 0.01 ENST00000368786.1
uroporphyrinogen III synthase
chr2_+_102928009 0.01 ENST00000404917.2
ENST00000447231.1
interleukin 1 receptor-like 1
chrX_+_24483338 0.01 ENST00000379162.4
ENST00000441463.2
pyruvate dehydrogenase kinase, isozyme 3
chr5_+_179159813 0.01 ENST00000292599.3
mastermind-like 1 (Drosophila)
chr6_-_11779174 0.01 ENST00000379413.2
androgen-dependent TFPI-regulating protein
chr3_+_130279178 0.01 ENST00000358511.6
ENST00000453409.2
collagen, type VI, alpha 6
chr11_-_82611448 0.01 ENST00000393399.2
ENST00000313010.3
prolylcarboxypeptidase (angiotensinase C)
chrM_+_7586 0.01 ENST00000361739.1
mitochondrially encoded cytochrome c oxidase II
chr22_-_30642728 0.01 ENST00000403987.3
leukemia inhibitory factor
chr2_-_20251744 0.01 ENST00000175091.4
lysosomal protein transmembrane 4 alpha
chr7_-_81399355 0.01 ENST00000457544.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr8_+_104831440 0.01 ENST00000515551.1
regulating synaptic membrane exocytosis 2
chr3_-_87325612 0.01 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU class 1 homeobox 1
chr15_+_69857515 0.01 ENST00000559477.1
RP11-279F6.1
chr8_+_41386761 0.01 ENST00000523277.2
GINS complex subunit 4 (Sld5 homolog)
chr15_-_37392086 0.01 ENST00000561208.1
Meis homeobox 2
chr9_-_114521783 0.01 ENST00000394779.3
ENST00000394777.4
chromosome 9 open reading frame 84
chr6_-_89927151 0.00 ENST00000454853.2
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr2_-_73869508 0.00 ENST00000272425.3
N-acetyltransferase 8 (GCN5-related, putative)
chrX_+_135388147 0.00 ENST00000394141.1
G protein-coupled receptor 112
chr13_+_78315295 0.00 ENST00000351546.3
SLAIN motif family, member 1
chr4_-_22444733 0.00 ENST00000508133.1
G protein-coupled receptor 125
chr3_+_113616317 0.00 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr8_+_104831554 0.00 ENST00000408894.2
regulating synaptic membrane exocytosis 2
chr17_-_6524159 0.00 ENST00000589033.1
KIAA0753
chr12_-_772901 0.00 ENST00000305108.4
ninjurin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:2000504 negative regulation of Fas signaling pathway(GO:1902045) positive regulation of blood vessel remodeling(GO:2000504)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0035529 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)