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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for SMAD2

Z-value: 0.84

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Transcription factors associated with SMAD2

Gene Symbol Gene ID Gene Info
SMAD2
ENSG00000175387.11 SMAD family member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD2hg19_v2_chr18_-_45456930_45456970-0.981.7e-02Click!

Activity profile of SMAD2 motif

Sorted Z-values of SMAD2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_7297833 0.73 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr19_+_11466062 0.57 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr18_+_20715416 0.57 ENST00000580153.1
CABLES1
Cdk5 and Abl enzyme substrate 1
chr19_+_50148087 0.50 ENST00000601038.1
ENST00000595242.1
SCAF1
SR-related CTD-associated factor 1
chr19_-_3551043 0.45 ENST00000589995.1
MFSD12
major facilitator superfamily domain containing 12
chr2_-_228028829 0.41 ENST00000396625.3
ENST00000329662.7
COL4A4
collagen, type IV, alpha 4
chr1_-_44482979 0.35 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_-_44497118 0.34 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr6_-_27841289 0.34 ENST00000355981.2
HIST1H4L
histone cluster 1, H4l
chr19_-_46272462 0.34 ENST00000317578.6
SIX5
SIX homeobox 5
chr22_+_37956479 0.31 ENST00000430687.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr19_+_49128209 0.30 ENST00000599748.1
ENST00000443164.1
ENST00000599029.1
SPHK2
sphingosine kinase 2
chr11_+_2923423 0.29 ENST00000312221.5
SLC22A18
solute carrier family 22, member 18
chr5_+_175298573 0.29 ENST00000512824.1
CPLX2
complexin 2
chr6_-_31612808 0.28 ENST00000438149.1
BAG6
BCL2-associated athanogene 6
chr17_-_40761375 0.28 ENST00000543197.1
ENST00000309428.5
FAM134C
family with sequence similarity 134, member C
chr8_-_142377367 0.28 ENST00000377741.3
GPR20
G protein-coupled receptor 20
chr19_+_11466167 0.27 ENST00000591608.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr12_+_53443963 0.27 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_195603566 0.27 ENST00000424563.1
ENST00000411741.1
TNK2
tyrosine kinase, non-receptor, 2
chr8_+_144373550 0.27 ENST00000330143.3
ENST00000521537.1
ENST00000518432.1
ENST00000520333.1
ZNF696
zinc finger protein 696
chr7_-_155601766 0.26 ENST00000430104.1
SHH
sonic hedgehog
chr19_+_56186557 0.26 ENST00000270460.6
EPN1
epsin 1
chr6_+_32132360 0.26 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGFL8
EGF-like-domain, multiple 8
chr6_+_30853002 0.24 ENST00000421124.2
ENST00000512725.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr16_+_31483374 0.24 ENST00000394863.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr11_-_3859089 0.24 ENST00000396979.1
RHOG
ras homolog family member G
chr22_+_45072925 0.23 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr1_+_33722080 0.23 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr20_+_43343476 0.23 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr20_+_43343886 0.23 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chrX_+_48660565 0.23 ENST00000413163.2
ENST00000441703.1
ENST00000426196.1
HDAC6
histone deacetylase 6
chr3_+_50316458 0.22 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr16_-_425205 0.22 ENST00000448854.1
TMEM8A
transmembrane protein 8A
chr4_+_102268904 0.22 ENST00000527564.1
ENST00000529296.1
AP001816.1
Uncharacterized protein
chr16_+_2198604 0.22 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr11_+_75273101 0.22 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr19_+_50094866 0.21 ENST00000418929.2
PRR12
proline rich 12
chr22_+_45072958 0.21 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr5_+_139493665 0.21 ENST00000331327.3
PURA
purine-rich element binding protein A
chr11_-_118789613 0.20 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr4_-_103749179 0.20 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr22_-_37823468 0.20 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr17_-_7297519 0.20 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr1_-_1243252 0.20 ENST00000353662.3
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr8_-_130587237 0.19 ENST00000520048.1
CCDC26
coiled-coil domain containing 26
chr19_+_56186606 0.19 ENST00000085079.7
EPN1
epsin 1
chr7_+_143080063 0.19 ENST00000446634.1
ZYX
zyxin
chr12_+_53443680 0.19 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr6_+_30852738 0.18 ENST00000508312.1
ENST00000512336.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_3571934 0.18 ENST00000225525.3
TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr11_-_65150103 0.17 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr11_-_75379479 0.17 ENST00000434603.2
MAP6
microtubule-associated protein 6
chr17_-_58469591 0.17 ENST00000589335.1
USP32
ubiquitin specific peptidase 32
chr16_+_30406423 0.16 ENST00000524644.1
ZNF48
zinc finger protein 48
chr21_+_47401650 0.16 ENST00000361866.3
COL6A1
collagen, type VI, alpha 1
chr2_-_74667612 0.15 ENST00000305557.5
ENST00000233330.6
RTKN
rhotekin
chr19_-_14606900 0.14 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC1
GIPC PDZ domain containing family, member 1
chr3_+_194406603 0.14 ENST00000329759.4
FAM43A
family with sequence similarity 43, member A
chr3_-_49761337 0.14 ENST00000535833.1
ENST00000308388.6
ENST00000480687.1
ENST00000308375.6
AMIGO3
GMPPB
adhesion molecule with Ig-like domain 3
GDP-mannose pyrophosphorylase B
chr16_-_54320675 0.14 ENST00000329734.3
IRX3
iroquois homeobox 3
chr16_+_58059470 0.14 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr1_-_149783914 0.14 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF
histone cluster 2, H2bf
chr2_+_113033164 0.14 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr21_-_47706098 0.14 ENST00000426537.1
MCM3AP
minichromosome maintenance complex component 3 associated protein
chr2_-_72375167 0.13 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr7_+_150758642 0.13 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr15_+_74509530 0.13 ENST00000321288.5
CCDC33
coiled-coil domain containing 33
chrX_+_48660287 0.13 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
HDAC6
histone deacetylase 6
chr12_+_122516626 0.13 ENST00000319080.7
MLXIP
MLX interacting protein
chrX_+_48660107 0.13 ENST00000376643.2
HDAC6
histone deacetylase 6
chr19_-_46105411 0.13 ENST00000323040.4
ENST00000544371.1
GPR4
OPA3
G protein-coupled receptor 4
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr1_-_149908217 0.13 ENST00000369140.3
MTMR11
myotubularin related protein 11
chr20_+_35974532 0.13 ENST00000373578.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr16_+_58549412 0.13 ENST00000447443.1
SETD6
SET domain containing 6
chr4_-_103749205 0.13 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr7_+_99905325 0.13 ENST00000332397.6
ENST00000437326.2
SPDYE3
speedy/RINGO cell cycle regulator family member E3
chr19_-_44285401 0.12 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr19_+_10527449 0.12 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_-_151119087 0.12 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr14_+_70078303 0.12 ENST00000342745.4
KIAA0247
KIAA0247
chr12_-_6798025 0.12 ENST00000542351.1
ENST00000538829.1
ZNF384
zinc finger protein 384
chr18_+_3448455 0.12 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr8_-_123706338 0.12 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr15_-_88799661 0.12 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr16_-_56459354 0.12 ENST00000290649.5
AMFR
autocrine motility factor receptor, E3 ubiquitin protein ligase
chr10_+_102821551 0.12 ENST00000370200.5
KAZALD1
Kazal-type serine peptidase inhibitor domain 1
chr5_+_140762268 0.11 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr20_+_43343517 0.11 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr17_-_15165825 0.11 ENST00000426385.3
PMP22
peripheral myelin protein 22
chr9_+_140145713 0.11 ENST00000388931.3
ENST00000412566.1
C9orf173
chromosome 9 open reading frame 173
chr11_+_64808675 0.11 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr11_-_117166201 0.11 ENST00000510915.1
BACE1
beta-site APP-cleaving enzyme 1
chr6_+_31730773 0.10 ENST00000415669.2
ENST00000425424.1
SAPCD1
suppressor APC domain containing 1
chr19_+_13106383 0.10 ENST00000397661.2
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_+_74881398 0.10 ENST00000339773.5
ENST00000434486.1
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr7_-_559853 0.10 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr1_-_153508460 0.09 ENST00000462776.2
S100A6
S100 calcium binding protein A6
chr6_+_41010293 0.09 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
TSPO2
translocator protein 2
chr22_-_43567750 0.09 ENST00000494035.1
TTLL12
tubulin tyrosine ligase-like family, member 12
chr1_+_16693578 0.09 ENST00000401088.4
ENST00000471507.1
ENST00000401089.3
ENST00000375590.3
ENST00000492354.1
SZRD1
SUZ RNA binding domain containing 1
chr1_-_149908710 0.09 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
MTMR11
myotubularin related protein 11
chr22_+_22676808 0.09 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr6_-_152489484 0.09 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr19_-_55580838 0.09 ENST00000396247.3
ENST00000586945.1
ENST00000587026.1
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr7_-_102257139 0.09 ENST00000521076.1
ENST00000462172.1
ENST00000522801.1
ENST00000449970.2
ENST00000262940.7
RASA4
RAS p21 protein activator 4
chr3_+_9834179 0.08 ENST00000498623.2
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr1_+_44412577 0.08 ENST00000372343.3
IPO13
importin 13
chr2_+_168725458 0.08 ENST00000392690.3
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr1_-_935491 0.08 ENST00000304952.6
HES4
hes family bHLH transcription factor 4
chrX_+_38420783 0.08 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr9_-_136006496 0.08 ENST00000372062.3
RALGDS
ral guanine nucleotide dissociation stimulator
chrX_+_38420623 0.08 ENST00000378482.2
TSPAN7
tetraspanin 7
chr7_-_10979750 0.08 ENST00000339600.5
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr9_-_140513231 0.08 ENST00000371417.3
C9orf37
chromosome 9 open reading frame 37
chr15_-_88799384 0.08 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr20_-_25062767 0.08 ENST00000429762.3
ENST00000444511.2
ENST00000376707.3
VSX1
visual system homeobox 1
chr12_+_47473369 0.07 ENST00000546455.1
PCED1B
PC-esterase domain containing 1B
chr11_-_65149422 0.07 ENST00000526432.1
ENST00000527174.1
SLC25A45
solute carrier family 25, member 45
chr9_+_34990219 0.07 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr4_-_140477353 0.07 ENST00000406354.1
ENST00000506866.2
SETD7
SET domain containing (lysine methyltransferase) 7
chr12_+_7037461 0.07 ENST00000396684.2
ATN1
atrophin 1
chr4_-_102268708 0.07 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr12_-_120241187 0.07 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr11_-_75380165 0.07 ENST00000304771.3
MAP6
microtubule-associated protein 6
chrX_-_47489244 0.07 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr12_+_68042517 0.06 ENST00000393555.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr4_-_39640513 0.06 ENST00000511809.1
ENST00000505729.1
SMIM14
small integral membrane protein 14
chr12_-_108991778 0.06 ENST00000549447.1
TMEM119
transmembrane protein 119
chr16_-_87417351 0.06 ENST00000311635.7
FBXO31
F-box protein 31
chrX_-_154688276 0.06 ENST00000369445.2
F8A3
coagulation factor VIII-associated 3
chr4_-_185139062 0.06 ENST00000296741.2
ENPP6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr16_-_67997947 0.06 ENST00000537830.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr9_-_73029540 0.06 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr15_+_75498739 0.06 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr17_+_7792101 0.06 ENST00000358181.4
ENST00000330494.7
CHD3
chromodomain helicase DNA binding protein 3
chr12_+_68042495 0.05 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr9_+_5890802 0.05 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
MLANA
melan-A
chr9_+_133569108 0.05 ENST00000372358.5
ENST00000546165.1
ENST00000372352.3
ENST00000372351.3
ENST00000372350.3
ENST00000495699.2
EXOSC2
exosome component 2
chr1_-_9189229 0.05 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr16_-_11681316 0.05 ENST00000571688.1
LITAF
lipopolysaccharide-induced TNF factor
chr16_-_17564738 0.05 ENST00000261381.6
XYLT1
xylosyltransferase I
chr11_-_33913708 0.05 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr8_-_20161466 0.05 ENST00000381569.1
LZTS1
leucine zipper, putative tumor suppressor 1
chr5_-_43412418 0.04 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr20_+_34680620 0.04 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr22_+_24891210 0.04 ENST00000382760.2
UPB1
ureidopropionase, beta
chr17_-_46623441 0.04 ENST00000330070.4
HOXB2
homeobox B2
chr17_+_30593195 0.04 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr16_-_3355645 0.04 ENST00000396862.1
ENST00000573608.1
TIGD7
tigger transposable element derived 7
chr9_-_130829588 0.04 ENST00000373078.4
NAIF1
nuclear apoptosis inducing factor 1
chr20_+_34020827 0.03 ENST00000374375.1
GDF5OS
growth differentiation factor 5 opposite strand
chr7_-_102158157 0.03 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
RASA4B
RAS p21 protein activator 4B
chr20_-_56284816 0.03 ENST00000395819.3
ENST00000341744.3
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_+_14143728 0.03 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr4_-_39640700 0.03 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr8_-_145641864 0.03 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr16_+_2286726 0.03 ENST00000382437.4
ENST00000569184.1
DNASE1L2
deoxyribonuclease I-like 2
chr5_+_140345820 0.03 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr4_-_164534657 0.03 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr3_-_195163584 0.03 ENST00000439666.1
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr17_+_3627185 0.03 ENST00000325418.4
GSG2
germ cell associated 2 (haspin)
chr12_+_110338323 0.03 ENST00000312777.5
ENST00000536408.2
TCHP
trichoplein, keratin filament binding
chr12_-_47473557 0.03 ENST00000321382.3
AMIGO2
adhesion molecule with Ig-like domain 2
chr3_+_40547483 0.03 ENST00000420891.1
ENST00000314529.6
ENST00000418905.1
ZNF620
zinc finger protein 620
chr16_+_57702099 0.03 ENST00000333493.4
ENST00000327655.6
GPR97
G protein-coupled receptor 97
chr10_-_14372870 0.03 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr1_+_174933899 0.03 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr5_+_133861339 0.02 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr9_+_125273081 0.02 ENST00000335302.5
OR1J2
olfactory receptor, family 1, subfamily J, member 2
chr22_-_24641027 0.02 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
GGT5
gamma-glutamyltransferase 5
chr17_+_40440094 0.02 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chr14_-_68159152 0.02 ENST00000554035.1
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr16_-_4987065 0.02 ENST00000590782.2
ENST00000345988.2
PPL
periplakin
chr6_-_143771799 0.02 ENST00000237283.8
ADAT2
adenosine deaminase, tRNA-specific 2
chr19_-_6501778 0.02 ENST00000596291.1
TUBB4A
tubulin, beta 4A class IVa
chr6_+_4087664 0.02 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr7_+_39125365 0.02 ENST00000559001.1
ENST00000464276.2
POU6F2
POU class 6 homeobox 2
chr16_+_58549378 0.02 ENST00000310682.2
ENST00000394266.4
ENST00000219315.4
SETD6
SET domain containing 6
chrX_+_24167746 0.02 ENST00000428571.1
ENST00000539115.1
ZFX
zinc finger protein, X-linked
chr20_+_1875942 0.02 ENST00000358771.4
SIRPA
signal-regulatory protein alpha
chr8_+_106331769 0.02 ENST00000520492.1
ZFPM2
zinc finger protein, FOG family member 2
chr5_-_114505591 0.01 ENST00000508894.1
TRIM36
tripartite motif containing 36
chr12_+_1800179 0.01 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr19_-_6481776 0.01 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C
DENN/MADD domain containing 1C
chr10_+_102729249 0.01 ENST00000519649.1
ENST00000518124.1
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr13_-_88323514 0.01 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr2_+_5832799 0.01 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr20_-_48532046 0.01 ENST00000543716.1
SPATA2
spermatogenesis associated 2
chr1_+_185703513 0.01 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr6_+_6588316 0.01 ENST00000379953.2
LY86
lymphocyte antigen 86
chr9_+_103790991 0.01 ENST00000374874.3
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr3_+_23847394 0.01 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr12_-_120554534 0.01 ENST00000538903.1
ENST00000534951.1
RAB35
RAB35, member RAS oncogene family
chr17_+_40761660 0.01 ENST00000251413.3
ENST00000591509.1
TUBG1
tubulin, gamma 1
chr17_-_46178741 0.01 ENST00000581003.1
ENST00000225603.4
CBX1
chromobox homolog 1
chr7_-_130080977 0.01 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr12_+_101188547 0.01 ENST00000546991.1
ENST00000392979.3
ANO4
anoctamin 4
chr8_+_95907993 0.00 ENST00000523378.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr12_-_57472522 0.00 ENST00000379391.3
ENST00000300128.4
TMEM194A
transmembrane protein 194A

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.5 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.3 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.3 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) sclerotome development(GO:0061056)
0.1 0.3 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.2 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.1 GO:0035981 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0072143 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:1905205 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.0 GO:0019482 beta-alanine metabolic process(GO:0019482)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.3 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation