Project
A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for SIN3A_CHD1
Z-value: 3.17
Motif logo
Transcription factors associated with SIN3A_CHD1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SIN3A | hg19_v2_chr15_-_75744014_75744087 | 0.99 | 1.4e-02 | Click! |
| CHD1 | hg19_v2_chr5_-_98262240_98262240 | 0.82 | 1.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_57466629 Show fit | 4.26 |
ENST00000371081.1
ENST00000338783.6 |
GNAS complex locus |
|
| chr9_+_128509663 Show fit | 2.91 |
ENST00000373489.5
ENST00000373483.2 |
pre-B-cell leukemia homeobox 3 |
|
| chr2_+_105471969 Show fit | 1.93 |
ENST00000361360.2
|
POU class 3 homeobox 3 |
|
| chr7_-_27239703 Show fit | 1.90 |
ENST00000222753.4
|
homeobox A13 |
|
| chr16_-_58231782 Show fit | 1.68 |
ENST00000565188.1
ENST00000262506.3 |
casein kinase 2, alpha prime polypeptide |
|
| chr19_+_35759824 Show fit | 1.66 |
ENST00000343550.5
|
upstream transcription factor 2, c-fos interacting |
|
| chr11_-_46142615 Show fit | 1.64 |
ENST00000529734.1
ENST00000323180.6 |
PHD finger protein 21A |
|
| chr3_+_19988885 Show fit | 1.62 |
ENST00000422242.1
|
RAB5A, member RAS oncogene family |
|
| chr8_+_26149274 Show fit | 1.60 |
ENST00000522535.1
|
protein phosphatase 2, regulatory subunit B, alpha |
|
| chr10_+_22610124 Show fit | 1.57 |
ENST00000376663.3
|
BMI1 polycomb ring finger oncogene |
Network of associatons between targets according to the STRING database.
First level regulatory network of SIN3A_CHD1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 7.1 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.0 | 5.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 5.5 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 1.1 | 4.3 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.1 | 4.3 | GO:0071174 | mitotic spindle checkpoint(GO:0071174) |
| 1.3 | 4.0 | GO:0007387 | anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388) |
| 0.1 | 3.4 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 3.2 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.3 | 3.0 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.4 | 2.9 | GO:0019086 | late viral transcription(GO:0019086) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.2 | 8.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 7.9 | GO:0044309 | neuron spine(GO:0044309) |
| 0.0 | 6.8 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.1 | 4.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 4.1 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 4.0 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 3.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 3.6 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 3.6 | GO:0005814 | centriole(GO:0005814) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 7.1 | GO:0051430 | corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.0 | 6.0 | GO:0061659 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 5.6 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 5.5 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
| 0.1 | 5.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 5.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 4.4 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.1 | 4.1 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.2 | 4.0 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.5 | 3.7 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 12.5 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 8.2 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 8.0 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 7.7 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 6.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 6.2 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.1 | 4.4 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 4.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 4.2 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 4.2 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 7.6 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.2 | 6.5 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.1 | 6.1 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 5.4 | REACTOME RNA POL II PRE TRANSCRIPTION EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
| 0.0 | 5.1 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 4.7 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 4.7 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 4.6 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 4.5 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |