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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for SCRT1_SCRT2
Z-value: 1.47
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Transcription factors associated with SCRT1_SCRT2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SCRT2 | hg19_v2_chr20_-_656823_656902 | -0.09 | 9.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_15496722 Show fit | 1.58 |
ENST00000472534.1
|
CMT1A duplicated region transcript 1 |
|
| chr2_+_10861775 Show fit | 1.02 |
ENST00000272238.4
ENST00000381661.3 |
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 |
|
| chr6_-_27440460 Show fit | 0.88 |
ENST00000377419.1
|
zinc finger protein 184 |
|
| chr4_-_6675550 Show fit | 0.88 |
ENST00000513179.1
ENST00000515205.1 |
RP11-539L10.3 |
|
| chr6_-_27440837 Show fit | 0.79 |
ENST00000211936.6
|
zinc finger protein 184 |
|
| chr4_+_165675197 Show fit | 0.73 |
ENST00000515485.1
|
RP11-294O2.2 |
|
| chr4_-_10117949 Show fit | 0.68 |
ENST00000508079.1
|
WD repeat domain 1 |
|
| chr1_+_109289279 Show fit | 0.68 |
ENST00000370008.3
|
syntaxin binding protein 3 |
|
| chr10_-_46342675 Show fit | 0.66 |
ENST00000492347.1
|
ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 |
|
| chr22_-_22090043 Show fit | 0.59 |
ENST00000403503.1
|
yippee-like 1 (Drosophila) |
Network of associatons between targets according to the STRING database.
First level regulatory network of SCRT1_SCRT2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 1.0 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.1 | 0.9 | GO:0032596 | protein transport into membrane raft(GO:0032596) |
| 0.2 | 0.8 | GO:0042247 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 0.2 | 0.8 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 0.1 | 0.8 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.1 | 0.7 | GO:0045955 | negative regulation of calcium ion-dependent exocytosis(GO:0045955) |
| 0.0 | 0.7 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.6 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.6 | GO:0051775 | response to redox state(GO:0051775) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.0 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 0.0 | 1.0 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 1.0 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.2 | 0.8 | GO:1902912 | pyruvate kinase complex(GO:1902912) |
| 0.2 | 0.8 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.0 | 0.7 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.0 | 0.6 | GO:0043219 | lateral loop(GO:0043219) |
| 0.0 | 0.5 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 0.5 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 0.4 | GO:0005726 | perichromatin fibrils(GO:0005726) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 0.8 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.0 | 0.7 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.7 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.6 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 0.5 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.1 | 0.5 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 0.5 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.0 | 0.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.7 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.5 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 1.0 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.8 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 0.8 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.5 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 0.5 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.4 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 0.2 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.2 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |