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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for RXRG
Z-value: 1.54
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Transcription factors associated with RXRG
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_149865377 Show fit | 2.65 |
ENST00000522491.1
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
|
| chr19_+_18451391 Show fit | 1.00 |
ENST00000269919.6
ENST00000604499.2 ENST00000595066.1 ENST00000252813.5 |
pyroglutamyl-peptidase I |
|
| chr1_+_109642799 Show fit | 0.90 |
ENST00000602755.1
|
small Cajal body-specific RNA 2 |
|
| chr7_+_2671663 Show fit | 0.84 |
ENST00000407643.1
|
tweety family member 3 |
|
| chr9_-_140009130 Show fit | 0.78 |
ENST00000497375.1
ENST00000371579.2 |
dipeptidyl-peptidase 7 |
|
| chr1_+_38273818 Show fit | 0.77 |
ENST00000373042.4
|
chromosome 1 open reading frame 122 |
|
| chr1_+_38273988 Show fit | 0.75 |
ENST00000446260.2
|
chromosome 1 open reading frame 122 |
|
| chr11_-_62380199 Show fit | 0.73 |
ENST00000419857.1
ENST00000394773.2 |
echinoderm microtubule associated protein like 3 |
|
| chr19_-_56632592 Show fit | 0.71 |
ENST00000587279.1
ENST00000270459.3 |
zinc finger protein 787 |
|
| chrX_-_30327495 Show fit | 0.69 |
ENST00000453287.1
|
nuclear receptor subfamily 0, group B, member 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of RXRG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.6 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.2 | 1.4 | GO:0032485 | Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485) |
| 0.2 | 1.4 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.1 | 1.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.2 | 1.2 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.1 | 1.1 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.0 | 1.1 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.2 | 1.0 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.1 | 1.0 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.1 | 1.0 | GO:0038203 | TORC2 signaling(GO:0038203) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 2.2 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.1 | 1.9 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 1.9 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.0 | 1.7 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 1.2 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 1.1 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 1.0 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.0 | 1.0 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 1.0 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.6 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.1 | 1.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 1.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.1 | 1.2 | GO:0048185 | activin binding(GO:0048185) |
| 0.2 | 1.1 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.1 | 1.1 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 1.1 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.3 | 1.0 | GO:0003881 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881) |
| 0.1 | 1.0 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.0 | 1.0 | GO:0008242 | omega peptidase activity(GO:0008242) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.0 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 1.1 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.5 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 0.4 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 2.1 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 1.6 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 1.3 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 1.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.0 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 1.0 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.9 | REACTOME SHC MEDIATED SIGNALLING | Genes involved in SHC-mediated signalling |
| 0.0 | 0.9 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |