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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for RFX5

Z-value: 0.62

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Transcription factors associated with RFX5

Gene Symbol Gene ID Gene Info
RFX5
ENSG00000143390.13 regulatory factor X5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX5hg19_v2_chr1_-_151319710_1513198330.996.7e-03Click!

Activity profile of RFX5 motif

Sorted Z-values of RFX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51014345 0.43 ENST00000391815.3
ENST00000594350.1
ENST00000601423.1
JOSD2
Josephin domain containing 2
chr1_+_249132512 0.30 ENST00000505503.1
ZNF672
zinc finger protein 672
chr19_+_50031547 0.24 ENST00000597801.1
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr1_+_249132462 0.21 ENST00000306562.3
ZNF672
zinc finger protein 672
chr6_+_26383318 0.21 ENST00000469230.1
ENST00000490025.1
ENST00000356709.4
ENST00000352867.2
ENST00000493275.1
ENST00000472507.1
ENST00000482536.1
ENST00000432533.2
ENST00000482842.1
BTN2A2
butyrophilin, subfamily 2, member A2
chr19_+_36103631 0.21 ENST00000203166.5
ENST00000379045.2
HAUS5
HAUS augmin-like complex, subunit 5
chr20_+_306177 0.21 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr1_-_208417620 0.20 ENST00000367033.3
PLXNA2
plexin A2
chr6_+_26440700 0.19 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr6_+_32821924 0.19 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr6_-_32908792 0.16 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_32812420 0.15 ENST00000374881.2
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr5_-_149792295 0.15 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr20_+_306221 0.15 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr11_+_66624527 0.15 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr6_-_32821599 0.14 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_-_72433346 0.14 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_-_19265855 0.14 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1
B9 protein domain 1
chr17_-_19266045 0.13 ENST00000395616.3
B9D1
B9 protein domain 1
chr6_+_26383404 0.13 ENST00000416795.2
ENST00000494184.1
BTN2A2
butyrophilin, subfamily 2, member A2
chr11_+_45868957 0.12 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr17_+_38137050 0.12 ENST00000264639.4
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr12_-_123565834 0.11 ENST00000546049.1
PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr1_+_114473350 0.11 ENST00000503968.1
HIPK1
homeodomain interacting protein kinase 1
chr1_-_27339317 0.10 ENST00000289166.5
FAM46B
family with sequence similarity 46, member B
chr17_-_19265982 0.10 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9D1
B9 protein domain 1
chr3_+_9851384 0.09 ENST00000419081.1
ENST00000438596.1
ENST00000417065.1
ENST00000439814.1
ENST00000418745.1
TTLL3
tubulin tyrosine ligase-like family, member 3
chr7_+_766320 0.08 ENST00000297440.6
ENST00000313147.5
HEATR2
HEAT repeat containing 2
chr6_-_30181133 0.08 ENST00000454678.2
ENST00000434785.1
TRIM26
tripartite motif containing 26
chr6_+_26365387 0.07 ENST00000532865.1
ENST00000530653.1
ENST00000527417.1
BTN3A2
butyrophilin, subfamily 3, member A2
chr6_-_30658745 0.06 ENST00000376420.5
ENST00000376421.5
NRM
nurim (nuclear envelope membrane protein)
chr6_-_32731299 0.06 ENST00000435145.2
ENST00000437316.2
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr6_-_30181156 0.06 ENST00000418026.1
ENST00000416596.1
ENST00000453195.1
TRIM26
tripartite motif containing 26
chr11_-_118436707 0.06 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr16_-_74808710 0.06 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr8_-_99306611 0.06 ENST00000341166.3
NIPAL2
NIPA-like domain containing 2
chr19_+_19496624 0.06 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A
GATA zinc finger domain containing 2A
chr4_-_83719884 0.05 ENST00000282709.4
ENST00000273908.4
SCD5
stearoyl-CoA desaturase 5
chr5_-_55412774 0.05 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr19_+_45417921 0.05 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr3_+_9850199 0.05 ENST00000452597.1
TTLL3
tubulin tyrosine ligase-like family, member 3
chr1_+_181003067 0.05 ENST00000434571.2
ENST00000367579.3
ENST00000282990.6
ENST00000367580.5
MR1
major histocompatibility complex, class I-related
chr13_-_30424821 0.05 ENST00000380680.4
UBL3
ubiquitin-like 3
chr3_+_66271489 0.05 ENST00000536651.1
SLC25A26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr19_+_45418067 0.04 ENST00000589078.1
ENST00000586638.1
APOC1
apolipoprotein C-I
chr10_-_82116505 0.04 ENST00000372202.1
ENST00000421924.2
ENST00000453477.1
DYDC1
DPY30 domain containing 1
chr6_-_32920794 0.04 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr8_-_99306564 0.04 ENST00000430223.2
NIPAL2
NIPA-like domain containing 2
chr3_+_66271410 0.04 ENST00000336733.6
SLC25A26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr1_-_202936394 0.04 ENST00000367249.4
CYB5R1
cytochrome b5 reductase 1
chr8_-_98290087 0.04 ENST00000322128.3
TSPYL5
TSPY-like 5
chr4_-_143226979 0.03 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_+_85527987 0.03 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr22_-_30987837 0.03 ENST00000335214.6
PES1
pescadillo ribosomal biogenesis factor 1
chr10_-_14880002 0.03 ENST00000465530.1
CDNF
cerebral dopamine neurotrophic factor
chr12_-_110841462 0.03 ENST00000455511.3
ENST00000450008.2
ANAPC7
anaphase promoting complex subunit 7
chr11_+_8008867 0.02 ENST00000309828.4
ENST00000449102.2
EIF3F
eukaryotic translation initiation factor 3, subunit F
chr6_+_26365443 0.02 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr2_-_242088850 0.02 ENST00000358649.4
ENST00000452907.1
ENST00000403638.3
ENST00000539818.1
ENST00000415234.1
ENST00000234040.4
PASK
PAS domain containing serine/threonine kinase
chr3_-_169587621 0.01 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr6_+_26458171 0.01 ENST00000493173.1
ENST00000541522.1
ENST00000429381.1
ENST00000469185.1
BTN2A1
butyrophilin, subfamily 2, member A1
chr17_+_38137073 0.01 ENST00000541736.1
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr19_+_10527449 0.00 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr6_+_32812568 0.00 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr19_+_19496728 0.00 ENST00000537887.1
ENST00000417582.2
GATAD2A
GATA zinc finger domain containing 2A

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0002503 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.2 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)