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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for REST
Z-value: 0.76
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Transcription factors associated with REST
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| REST | hg19_v2_chr4_+_57774042_57774114 | -0.17 | 8.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_+_31199037 Show fit | 0.61 |
ENST00000424224.1
|
oxysterol binding protein 2 |
|
| chr10_+_99609996 Show fit | 0.44 |
ENST00000370602.1
|
golgin A7 family, member B |
|
| chr14_+_96039882 Show fit | 0.43 |
ENST00000556346.1
ENST00000553785.1 |
RP11-1070N10.4 |
|
| chr12_+_52695617 Show fit | 0.40 |
ENST00000293525.5
|
keratin 86 |
|
| chr19_+_39759154 Show fit | 0.38 |
ENST00000331982.5
|
interferon, lambda 2 |
|
| chr19_-_40724246 Show fit | 0.36 |
ENST00000311308.6
|
tetratricopeptide repeat domain 9B |
|
| chr12_-_12837423 Show fit | 0.36 |
ENST00000540510.1
|
G protein-coupled receptor 19 |
|
| chr20_+_62327996 Show fit | 0.33 |
ENST00000369996.1
|
tumor necrosis factor receptor superfamily, member 6b, decoy |
|
| chr2_-_27531313 Show fit | 0.27 |
ENST00000296099.2
|
urocortin |
|
| chrX_-_153141434 Show fit | 0.27 |
ENST00000407935.2
ENST00000439496.1 |
L1 cell adhesion molecule |
Network of associatons between targets according to the STRING database.
First level regulatory network of REST
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.0 | 0.4 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.0 | 0.4 | GO:0002385 | mucosal immune response(GO:0002385) |
| 0.1 | 0.3 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
| 0.1 | 0.2 | GO:0021722 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 0.1 | 0.2 | GO:0060164 | negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) regulation of timing of neuron differentiation(GO:0060164) negative regulation of inner ear receptor cell differentiation(GO:2000981) |
| 0.0 | 0.2 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
| 0.0 | 0.2 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.0 | 0.2 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.0 | 0.2 | GO:1902075 | cellular response to salt(GO:1902075) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 0.6 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.0 | 0.4 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.0 | 0.3 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 0.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.0 | 0.2 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.0 | 0.2 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.0 | 0.1 | GO:0002139 | stereocilia coupling link(GO:0002139) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 0.3 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 2 binding(GO:0051431) |
| 0.1 | 0.2 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.0 | 0.2 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 0.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.2 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 0.1 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.0 | 0.0 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.0 | 0.0 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.1 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |