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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for RBPJ
Z-value: 0.82
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Transcription factors associated with RBPJ
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RBPJ | hg19_v2_chr4_+_26322987_26323031 | 0.73 | 2.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_38146965 Show fit | 0.48 |
ENST00000395873.3
ENST00000357328.4 ENST00000395874.2 |
zinc finger protein 248 |
|
| chr8_-_80680078 Show fit | 0.42 |
ENST00000337919.5
ENST00000354724.3 |
hes-related family bHLH transcription factor with YRPW motif 1 |
|
| chr1_-_197744763 Show fit | 0.36 |
ENST00000422998.1
|
DENN/MADD domain containing 1B |
|
| chr20_+_32250079 Show fit | 0.34 |
ENST00000375222.3
|
chromosome 20 open reading frame 144 |
|
| chr3_-_45957534 Show fit | 0.34 |
ENST00000536047.1
|
leucine zipper transcription factor-like 1 |
|
| chr15_+_59730348 Show fit | 0.34 |
ENST00000288228.5
ENST00000559628.1 ENST00000557914.1 ENST00000560474.1 |
family with sequence similarity 81, member A |
|
| chrX_-_46187069 Show fit | 0.31 |
ENST00000446884.1
|
RP1-30G7.2 |
|
| chr3_-_45957088 Show fit | 0.30 |
ENST00000539217.1
|
leucine zipper transcription factor-like 1 |
|
| chr3_+_32726774 Show fit | 0.28 |
ENST00000538368.1
|
CCR4-NOT transcription complex, subunit 10 |
|
| chr6_+_144665237 Show fit | 0.27 |
ENST00000421035.2
|
utrophin |
Network of associatons between targets according to the STRING database.
First level regulatory network of RBPJ
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | GO:1903565 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 0.2 | 0.6 | GO:2000820 | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820) |
| 0.0 | 0.5 | GO:0035745 | T-helper 2 cell cytokine production(GO:0035745) |
| 0.1 | 0.3 | GO:0061534 | gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) |
| 0.0 | 0.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 0.3 | GO:0006828 | manganese ion transport(GO:0006828) |
| 0.0 | 0.3 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 0.3 | GO:0043584 | nose development(GO:0043584) |
| 0.1 | 0.2 | GO:0035910 | ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.1 | 0.2 | GO:0072361 | regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.4 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 0.3 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.0 | 0.3 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 0.2 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 0.0 | 0.2 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.0 | 0.2 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 0.2 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 0.1 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.1 | GO:0031417 | NatC complex(GO:0031417) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.0 | 0.4 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 0.3 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 0.0 | 0.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 0.3 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 0.2 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.0 | 0.2 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.0 | 0.2 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.0 | 0.1 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.1 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.1 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 0.1 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |