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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for RAD21_SMC3

Z-value: 0.84

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Transcription factors associated with RAD21_SMC3

Gene Symbol Gene ID Gene Info
RAD21
ENSG00000164754.8 RAD21 cohesin complex component
SMC3
ENSG00000108055.9 structural maintenance of chromosomes 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMC3hg19_v2_chr10_+_112327425_112327516-0.997.7e-03Click!
RAD21hg19_v2_chr8_-_117886955_117887105-0.919.4e-02Click!

Activity profile of RAD21_SMC3 motif

Sorted Z-values of RAD21_SMC3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_302918 1.61 ENST00000599994.1
AC187652.1
Protein LOC100996433
chr10_-_76995769 1.00 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr10_-_76995675 0.86 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr1_-_186344802 0.80 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr8_+_22446763 0.73 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
AC037459.4
Uncharacterized protein
chr19_+_38893809 0.72 ENST00000589408.1
FAM98C
family with sequence similarity 98, member C
chr1_+_840205 0.60 ENST00000607769.1
RP11-54O7.16
RP11-54O7.16
chr11_+_2421718 0.60 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4
tumor suppressing subtransferable candidate 4
chr6_-_44225231 0.57 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr20_-_34542548 0.56 ENST00000305978.2
SCAND1
SCAN domain containing 1
chr19_-_4400415 0.56 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3GL1
SH3-domain GRB2-like 1
chr9_-_139940608 0.56 ENST00000371601.4
NPDC1
neural proliferation, differentiation and control, 1
chr20_+_3801162 0.55 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
AP5S1
adaptor-related protein complex 5, sigma 1 subunit
chr8_-_145550571 0.51 ENST00000332324.4
DGAT1
diacylglycerol O-acyltransferase 1
chr7_+_73082152 0.49 ENST00000324941.4
ENST00000451519.1
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr11_+_60691924 0.49 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr1_+_109642799 0.47 ENST00000602755.1
SCARNA2
small Cajal body-specific RNA 2
chr20_+_48807351 0.47 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr16_+_75032901 0.45 ENST00000335325.4
ENST00000320619.6
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr22_-_24316648 0.45 ENST00000403754.3
ENST00000430101.2
ENST00000398344.4
DDT
D-dopachrome tautomerase
chr1_-_139379 0.44 ENST00000423372.3
AL627309.1
Uncharacterized protein
chr19_-_59030921 0.43 ENST00000354590.3
ENST00000596739.1
ZBTB45
zinc finger and BTB domain containing 45
chrX_-_153279697 0.42 ENST00000444254.1
IRAK1
interleukin-1 receptor-associated kinase 1
chr8_-_48651648 0.42 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr19_-_3547305 0.40 ENST00000589063.1
MFSD12
major facilitator superfamily domain containing 12
chr19_-_49339080 0.40 ENST00000595764.1
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr19_-_33793430 0.39 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr7_-_5569588 0.39 ENST00000417101.1
ACTB
actin, beta
chr19_-_1876156 0.39 ENST00000565797.1
CTB-31O20.2
CTB-31O20.2
chr7_-_100171270 0.39 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr17_-_73511584 0.38 ENST00000321617.3
CASKIN2
CASK interacting protein 2
chr2_-_24307635 0.38 ENST00000313482.4
TP53I3
tumor protein p53 inducible protein 3
chr3_+_49209023 0.37 ENST00000332780.2
KLHDC8B
kelch domain containing 8B
chr22_-_30783075 0.37 ENST00000215798.6
RNF215
ring finger protein 215
chr9_+_116917807 0.37 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr8_-_145550337 0.37 ENST00000531896.1
DGAT1
diacylglycerol O-acyltransferase 1
chr17_-_42441204 0.36 ENST00000293443.7
FAM171A2
family with sequence similarity 171, member A2
chr8_-_145911188 0.36 ENST00000540274.1
ARHGAP39
Rho GTPase activating protein 39
chr14_-_75079294 0.35 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr19_+_4791722 0.35 ENST00000269856.3
FEM1A
fem-1 homolog a (C. elegans)
chr17_-_61523622 0.35 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
CYB561
cytochrome b561
chr12_-_8549301 0.34 ENST00000544461.1
LINC00937
long intergenic non-protein coding RNA 937
chr20_+_43992094 0.33 ENST00000453003.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr17_-_36891830 0.33 ENST00000578487.1
PCGF2
polycomb group ring finger 2
chr9_+_131903916 0.33 ENST00000419582.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr22_-_22292934 0.33 ENST00000538191.1
ENST00000424647.1
ENST00000407142.1
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr2_+_113342163 0.33 ENST00000409719.1
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr9_+_140317802 0.33 ENST00000341349.2
ENST00000392815.2
NOXA1
NADPH oxidase activator 1
chr9_+_139738867 0.32 ENST00000436881.1
C9orf172
chromosome 9 open reading frame 172
chr12_+_58176525 0.32 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr17_+_74864476 0.32 ENST00000301618.4
ENST00000569840.2
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr9_+_131182697 0.32 ENST00000372838.4
ENST00000411852.1
CERCAM
cerebral endothelial cell adhesion molecule
chr6_-_30043539 0.32 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr19_+_37407212 0.32 ENST00000427117.1
ENST00000587130.1
ENST00000333987.7
ENST00000415168.1
ENST00000444991.1
ZNF568
zinc finger protein 568
chr11_-_117102768 0.31 ENST00000532301.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr11_-_66104237 0.31 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr12_-_7245018 0.31 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr19_+_38893751 0.30 ENST00000588262.1
ENST00000252530.5
ENST00000343358.7
FAM98C
family with sequence similarity 98, member C
chr22_-_30783356 0.30 ENST00000382363.3
RNF215
ring finger protein 215
chr20_+_32319463 0.30 ENST00000342427.2
ENST00000375200.1
ZNF341
zinc finger protein 341
chr16_-_88851618 0.30 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr17_-_43209862 0.30 ENST00000322765.5
PLCD3
phospholipase C, delta 3
chr19_-_1863567 0.29 ENST00000250916.4
KLF16
Kruppel-like factor 16
chr1_-_63782888 0.29 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr4_-_164253738 0.29 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
NPY1R
neuropeptide Y receptor Y1
chr11_-_65150103 0.29 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr14_-_93582214 0.29 ENST00000556603.2
ENST00000354313.3
ITPK1
inositol-tetrakisphosphate 1-kinase
chr5_-_125930877 0.28 ENST00000510111.2
ENST00000509270.1
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr8_-_11873043 0.28 ENST00000527396.1
RP11-481A20.11
Protein LOC101060662
chr16_+_69345243 0.28 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr2_-_220025263 0.27 ENST00000457600.1
NHEJ1
nonhomologous end-joining factor 1
chr8_-_66474884 0.27 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr8_+_42948641 0.27 ENST00000518991.1
ENST00000331373.5
POMK
protein-O-mannose kinase
chr2_-_24307162 0.27 ENST00000413037.1
ENST00000407482.1
TP53I3
tumor protein p53 inducible protein 3
chr1_-_156390128 0.27 ENST00000368242.3
C1orf61
chromosome 1 open reading frame 61
chr4_+_76649753 0.27 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr19_-_1848451 0.27 ENST00000170168.4
REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr16_+_230435 0.26 ENST00000199708.2
HBQ1
hemoglobin, theta 1
chr19_+_41699103 0.26 ENST00000597754.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr2_+_232316906 0.26 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr11_-_66103932 0.26 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr12_-_58159361 0.26 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr4_+_2043777 0.25 ENST00000409860.1
C4orf48
chromosome 4 open reading frame 48
chr15_+_75074385 0.25 ENST00000220003.9
CSK
c-src tyrosine kinase
chr17_-_73901494 0.25 ENST00000309352.3
MRPL38
mitochondrial ribosomal protein L38
chr17_+_17584763 0.25 ENST00000353383.1
RAI1
retinoic acid induced 1
chr4_+_2043689 0.24 ENST00000382878.3
ENST00000409248.4
C4orf48
chromosome 4 open reading frame 48
chr16_-_19897455 0.24 ENST00000568214.1
ENST00000569479.1
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr17_+_42427826 0.24 ENST00000586443.1
GRN
granulin
chr17_+_43213004 0.24 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
ACBD4
acyl-CoA binding domain containing 4
chr9_-_140317605 0.24 ENST00000479452.1
ENST00000465160.2
EXD3
exonuclease 3'-5' domain containing 3
chr11_-_66103867 0.24 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr20_-_33460621 0.24 ENST00000427420.1
ENST00000336431.5
GGT7
gamma-glutamyltransferase 7
chr10_+_104154229 0.24 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr12_-_51663959 0.24 ENST00000604188.1
ENST00000398453.3
SMAGP
small cell adhesion glycoprotein
chr22_-_22307199 0.24 ENST00000397495.4
ENST00000263212.5
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr11_-_72504637 0.24 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr3_+_48507210 0.23 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr1_+_28844778 0.23 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr5_-_146833803 0.23 ENST00000512722.1
DPYSL3
dihydropyrimidinase-like 3
chr9_+_33617760 0.23 ENST00000379435.3
TRBV20OR9-2
T cell receptor beta variable 20/OR9-2 (non-functional)
chr17_+_38137050 0.23 ENST00000264639.4
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr1_+_36348790 0.22 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr1_+_1370903 0.22 ENST00000338660.5
ENST00000404702.3
ENST00000476993.1
ENST00000471398.1
VWA1
von Willebrand factor A domain containing 1
chr2_+_232575168 0.22 ENST00000440384.1
PTMA
prothymosin, alpha
chr10_+_102759045 0.22 ENST00000370220.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr19_+_8478154 0.22 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr17_-_73511504 0.22 ENST00000581870.1
CASKIN2
CASK interacting protein 2
chr19_-_58400148 0.22 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
ZNF814
zinc finger protein 814
chr2_+_166095898 0.22 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr11_+_61520075 0.22 ENST00000278836.5
MYRF
myelin regulatory factor
chr10_-_103603523 0.22 ENST00000370046.1
KCNIP2
Kv channel interacting protein 2
chr8_-_145669791 0.22 ENST00000409379.3
TONSL
tonsoku-like, DNA repair protein
chr16_-_2390704 0.21 ENST00000301732.5
ENST00000382381.3
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr17_-_33446820 0.21 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr19_+_48216600 0.21 ENST00000263277.3
ENST00000538399.1
EHD2
EH-domain containing 2
chr19_+_23945768 0.21 ENST00000486528.1
ENST00000496398.1
RPSAP58
ribosomal protein SA pseudogene 58
chr12_+_7033616 0.21 ENST00000356654.4
ATN1
atrophin 1
chr12_-_7245080 0.21 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chr17_+_48556158 0.21 ENST00000258955.2
RSAD1
radical S-adenosyl methionine domain containing 1
chr3_-_49967292 0.21 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chr9_-_35096545 0.21 ENST00000378617.3
ENST00000341666.3
ENST00000361778.2
PIGO
phosphatidylinositol glycan anchor biosynthesis, class O
chr16_+_30406721 0.21 ENST00000320159.2
ZNF48
zinc finger protein 48
chr10_-_71906342 0.21 ENST00000287078.6
ENST00000335494.5
TYSND1
trypsin domain containing 1
chr1_+_112298514 0.21 ENST00000536167.1
DDX20
DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
chr11_+_46368956 0.20 ENST00000543978.1
DGKZ
diacylglycerol kinase, zeta
chr12_-_7245152 0.20 ENST00000542220.2
C1R
complement component 1, r subcomponent
chr9_+_139560197 0.20 ENST00000371698.3
EGFL7
EGF-like-domain, multiple 7
chr2_+_239067597 0.20 ENST00000546354.1
FAM132B
family with sequence similarity 132, member B
chr11_+_46369077 0.20 ENST00000456247.2
ENST00000421244.2
ENST00000318201.8
DGKZ
diacylglycerol kinase, zeta
chr9_+_131901661 0.20 ENST00000423100.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr11_-_85565906 0.20 ENST00000544076.1
AP000974.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
chrX_-_27417088 0.20 ENST00000608735.1
ENST00000422048.1
RP11-268G12.1
RP11-268G12.1
chr19_+_56165480 0.20 ENST00000450554.2
U2AF2
U2 small nuclear RNA auxiliary factor 2
chr9_-_139258235 0.19 ENST00000371738.3
DNLZ
DNL-type zinc finger
chr12_-_7261772 0.19 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr1_+_29563011 0.19 ENST00000345512.3
ENST00000373779.3
ENST00000356870.3
ENST00000323874.8
ENST00000428026.2
ENST00000460170.2
PTPRU
protein tyrosine phosphatase, receptor type, U
chr14_+_105957402 0.19 ENST00000421892.1
ENST00000334656.7
ENST00000451719.1
ENST00000392522.3
ENST00000392523.4
ENST00000354560.6
ENST00000450383.1
C14orf80
chromosome 14 open reading frame 80
chr20_+_36531499 0.19 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L
V-set and transmembrane domain containing 2 like
chr6_-_83775489 0.19 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr17_-_45908875 0.19 ENST00000351111.2
ENST00000414011.1
MRPL10
mitochondrial ribosomal protein L10
chr19_+_42829702 0.19 ENST00000334370.4
MEGF8
multiple EGF-like-domains 8
chr11_+_65627974 0.18 ENST00000525768.1
MUS81
MUS81 structure-specific endonuclease subunit
chr17_+_7591639 0.18 ENST00000396463.2
WRAP53
WD repeat containing, antisense to TP53
chr12_-_120638902 0.18 ENST00000551150.1
ENST00000313104.5
ENST00000547191.1
ENST00000546989.1
ENST00000392514.4
ENST00000228306.4
ENST00000550856.1
RPLP0
ribosomal protein, large, P0
chr21_-_44846999 0.18 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr17_+_73996987 0.18 ENST00000588812.1
ENST00000448471.1
CDK3
cyclin-dependent kinase 3
chr1_+_2258581 0.18 ENST00000600779.1
AL589739.1
Uncharacterized protein
chr1_-_17766198 0.18 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr6_-_18122843 0.18 ENST00000340650.3
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1
chr2_-_74710078 0.18 ENST00000290418.4
CCDC142
coiled-coil domain containing 142
chr17_+_7621045 0.17 ENST00000570791.1
DNAH2
dynein, axonemal, heavy chain 2
chr6_+_35310312 0.17 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr5_+_150827143 0.17 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr9_-_117160738 0.17 ENST00000448674.1
RP11-9M16.2
RP11-9M16.2
chrX_+_47053208 0.17 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
UBA1
ubiquitin-like modifier activating enzyme 1
chr5_-_180237082 0.17 ENST00000506889.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr16_+_4674787 0.17 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr19_+_47852538 0.17 ENST00000328771.4
DHX34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr5_+_140254884 0.17 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr15_+_75074410 0.17 ENST00000439220.2
CSK
c-src tyrosine kinase
chr9_-_139258159 0.17 ENST00000371739.3
DNLZ
DNL-type zinc finger
chr22_-_19132154 0.17 ENST00000252137.6
DGCR14
DiGeorge syndrome critical region gene 14
chr9_+_133884469 0.16 ENST00000361069.4
LAMC3
laminin, gamma 3
chr16_-_84220604 0.16 ENST00000567759.1
TAF1C
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
chr1_+_16767195 0.16 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP2
NECAP endocytosis associated 2
chr4_-_41884620 0.16 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr10_-_103603568 0.16 ENST00000356640.2
KCNIP2
Kv channel interacting protein 2
chr17_-_33446735 0.15 ENST00000460118.2
ENST00000335858.7
RAD51D
RAD51 paralog D
chr16_+_29827285 0.15 ENST00000320330.6
PAGR1
PAXIP1 associated glutamate-rich protein 1
chr11_+_64948665 0.15 ENST00000533820.1
CAPN1
calpain 1, (mu/I) large subunit
chr17_+_38137073 0.15 ENST00000541736.1
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr11_-_119599794 0.15 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr2_+_196440692 0.15 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr11_-_798305 0.15 ENST00000531514.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr11_+_67033881 0.15 ENST00000308595.5
ENST00000526285.1
ADRBK1
adrenergic, beta, receptor kinase 1
chr3_+_58291965 0.15 ENST00000445193.3
ENST00000295959.5
ENST00000466547.1
RPP14
ribonuclease P/MRP 14kDa subunit
chr11_+_46368975 0.15 ENST00000527911.1
DGKZ
diacylglycerol kinase, zeta
chr7_+_112120908 0.15 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
LSMEM1
leucine-rich single-pass membrane protein 1
chr17_+_7591747 0.15 ENST00000534050.1
WRAP53
WD repeat containing, antisense to TP53
chr2_-_20850813 0.15 ENST00000402541.1
ENST00000406618.3
ENST00000304031.3
HS1BP3
HCLS1 binding protein 3
chr19_+_36027660 0.15 ENST00000585510.1
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr5_+_176513895 0.15 ENST00000503708.1
ENST00000393648.2
ENST00000514472.1
ENST00000502906.1
ENST00000292410.3
ENST00000510911.1
FGFR4
fibroblast growth factor receptor 4
chr6_-_34216766 0.14 ENST00000481533.1
ENST00000468145.1
ENST00000413013.2
ENST00000394990.4
ENST00000335352.3
C6orf1
chromosome 6 open reading frame 1
chr21_+_45725050 0.14 ENST00000403390.1
PFKL
phosphofructokinase, liver
chr19_-_59031118 0.14 ENST00000600990.1
ZBTB45
zinc finger and BTB domain containing 45
chr7_+_6629701 0.14 ENST00000359073.5
C7orf26
chromosome 7 open reading frame 26
chr8_+_67341239 0.14 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr11_-_130786400 0.14 ENST00000265909.4
SNX19
sorting nexin 19
chr17_-_33469299 0.14 ENST00000586869.1
ENST00000360831.5
ENST00000442241.4
NLE1
notchless homolog 1 (Drosophila)
chr7_-_100425112 0.14 ENST00000358173.3
EPHB4
EPH receptor B4
chr5_+_176514413 0.14 ENST00000513166.1
FGFR4
fibroblast growth factor receptor 4
chr1_+_6640046 0.14 ENST00000319084.5
ENST00000435905.1
ZBTB48
zinc finger and BTB domain containing 48
chr20_-_30539773 0.13 ENST00000202017.4
PDRG1
p53 and DNA-damage regulated 1
chr12_-_56652111 0.13 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr22_+_24204375 0.13 ENST00000433835.3
AP000350.10
Uncharacterized protein
chr4_-_140216948 0.13 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr7_+_148959262 0.13 ENST00000434415.1
ZNF783
zinc finger family member 783
chr1_+_16767167 0.13 ENST00000337132.5
NECAP2
NECAP endocytosis associated 2
chr12_-_120703523 0.12 ENST00000267257.7
ENST00000228307.7
ENST00000424649.2
PXN
paxillin

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.3 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.9 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 0.4 GO:1903412 response to bile acid(GO:1903412)
0.1 0.2 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.3 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.2 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.6 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.1 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.2 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.0 0.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.3 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.2 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.4 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0044416 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:1902988 neurofibrillary tangle assembly(GO:1902988)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.1 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808) proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0002503 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:2000504 negative regulation of Fas signaling pathway(GO:1902045) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.6 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.4 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0000806 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.2 0.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.4 GO:0052830 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.4 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.1 0.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.2 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.1 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.4 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.0 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.0 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.9 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules