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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for PPARD

Z-value: 0.43

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Transcription factors associated with PPARD

Gene Symbol Gene ID Gene Info
PPARD
ENSG00000112033.9 peroxisome proliferator activated receptor delta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARDhg19_v2_chr6_+_35310391_353104100.972.6e-02Click!

Activity profile of PPARD motif

Sorted Z-values of PPARD motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_76030311 0.34 ENST00000543887.1
AC019294.1
AC019294.1
chr19_-_49339080 0.21 ENST00000595764.1
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr1_+_145727681 0.21 ENST00000417171.1
ENST00000451928.2
PDZK1
PDZ domain containing 1
chr17_+_7123207 0.19 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr15_+_82555125 0.17 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr7_+_7222157 0.16 ENST00000419721.1
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr17_-_71223839 0.16 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr3_-_53878644 0.16 ENST00000481668.1
ENST00000467802.1
CHDH
choline dehydrogenase
chr11_+_64073699 0.16 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr3_-_50605077 0.15 ENST00000426034.1
ENST00000441239.1
C3orf18
chromosome 3 open reading frame 18
chr19_+_10196981 0.15 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr11_+_111169565 0.14 ENST00000528846.1
COLCA2
colorectal cancer associated 2
chr11_-_45939565 0.13 ENST00000525192.1
ENST00000378750.5
PEX16
peroxisomal biogenesis factor 16
chr12_+_121163602 0.12 ENST00000411593.2
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr7_+_75911902 0.12 ENST00000413003.1
SRRM3
serine/arginine repetitive matrix 3
chr9_-_33402506 0.12 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7
aquaporin 7
chr16_+_81272287 0.12 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr12_-_109219937 0.12 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr1_+_43855545 0.12 ENST00000372450.4
ENST00000310739.4
SZT2
seizure threshold 2 homolog (mouse)
chr19_-_10687907 0.11 ENST00000589348.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr2_+_159651821 0.10 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr11_+_111169976 0.10 ENST00000398035.2
COLCA2
colorectal cancer associated 2
chr17_+_9745786 0.10 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr3_-_49314640 0.10 ENST00000436325.1
C3orf62
chromosome 3 open reading frame 62
chr5_-_143550241 0.10 ENST00000522203.1
YIPF5
Yip1 domain family, member 5
chr12_-_109797249 0.09 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr11_-_45939374 0.09 ENST00000533151.1
ENST00000241041.3
PEX16
peroxisomal biogenesis factor 16
chr12_+_121163538 0.08 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr11_-_116968987 0.08 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr6_+_31637944 0.07 ENST00000375864.4
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr3_-_49203744 0.07 ENST00000321895.6
CCDC71
coiled-coil domain containing 71
chr16_-_75284758 0.07 ENST00000561970.1
BCAR1
breast cancer anti-estrogen resistance 1
chr11_-_61659006 0.06 ENST00000278829.2
FADS3
fatty acid desaturase 3
chr6_-_33548006 0.06 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr5_-_176981417 0.06 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
FAM193B
family with sequence similarity 193, member B
chr6_-_33547975 0.06 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr17_+_48610074 0.05 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr19_+_10197463 0.05 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr10_-_103815874 0.05 ENST00000370033.4
ENST00000311122.5
C10orf76
chromosome 10 open reading frame 76
chr2_-_198364552 0.05 ENST00000439605.1
ENST00000418022.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr19_+_29493486 0.05 ENST00000589821.1
CTD-2081K17.2
CTD-2081K17.2
chr2_+_198365122 0.05 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr11_-_61658853 0.05 ENST00000525588.1
ENST00000540820.1
FADS3
fatty acid desaturase 3
chr8_-_135652051 0.05 ENST00000522257.1
ZFAT
zinc finger and AT hook domain containing
chr11_-_47470703 0.05 ENST00000298854.2
RAPSN
receptor-associated protein of the synapse
chr17_+_7123125 0.04 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL
acyl-CoA dehydrogenase, very long chain
chr9_+_131901661 0.04 ENST00000423100.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr15_+_91449971 0.04 ENST00000557865.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr19_+_49867181 0.04 ENST00000597546.1
DKKL1
dickkopf-like 1
chr1_+_202317815 0.04 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr13_+_113760098 0.04 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
F7
coagulation factor VII (serum prothrombin conversion accelerator)
chr5_+_14664762 0.04 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr16_-_28303360 0.04 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr2_+_95940186 0.04 ENST00000403131.2
ENST00000317668.4
ENST00000317620.9
PROM2
prominin 2
chr15_+_75494214 0.03 ENST00000394987.4
C15orf39
chromosome 15 open reading frame 39
chr19_-_51869592 0.03 ENST00000596253.1
ENST00000309244.4
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr1_-_153917700 0.03 ENST00000368646.2
DENND4B
DENN/MADD domain containing 4B
chr16_-_4401284 0.03 ENST00000318059.3
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr20_+_39969519 0.03 ENST00000373257.3
LPIN3
lipin 3
chr1_+_43855560 0.03 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr14_-_51561784 0.03 ENST00000360392.4
TRIM9
tripartite motif containing 9
chr11_-_119599794 0.03 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr17_-_7123021 0.03 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr20_+_32077880 0.03 ENST00000342704.6
ENST00000375279.2
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr1_-_11863171 0.03 ENST00000376592.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr4_+_140586922 0.02 ENST00000265498.1
ENST00000506797.1
MGST2
microsomal glutathione S-transferase 2
chr10_-_94050820 0.02 ENST00000265997.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr16_-_74808710 0.02 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr2_+_178257372 0.02 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chrX_-_108868390 0.02 ENST00000372101.2
KCNE1L
KCNE1-like
chr6_-_135424186 0.02 ENST00000529882.1
HBS1L
HBS1-like (S. cerevisiae)
chr21_-_27107283 0.02 ENST00000284971.3
ENST00000400099.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chrX_+_2746818 0.02 ENST00000398806.3
GYG2
glycogenin 2
chr17_+_37894179 0.02 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
GRB7
growth factor receptor-bound protein 7
chr2_+_39117010 0.02 ENST00000409978.1
ARHGEF33
Rho guanine nucleotide exchange factor (GEF) 33
chr2_-_159313214 0.02 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
CCDC148
coiled-coil domain containing 148
chr20_+_46130601 0.02 ENST00000341724.6
NCOA3
nuclear receptor coactivator 3
chr11_-_47470591 0.02 ENST00000524487.1
RAPSN
receptor-associated protein of the synapse
chr2_-_207024134 0.02 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr20_-_44485835 0.02 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8
acyl-CoA thioesterase 8
chr1_+_244998602 0.01 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr19_-_10687948 0.01 ENST00000592285.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_+_11546153 0.01 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH
protein kinase C substrate 80K-H
chr19_-_10687983 0.01 ENST00000587069.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr12_-_56727487 0.01 ENST00000548043.1
ENST00000425394.2
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_+_120125245 0.01 ENST00000393103.2
DBI
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr19_+_29493456 0.01 ENST00000591143.1
ENST00000592653.1
CTD-2081K17.2
CTD-2081K17.2
chr15_-_43865633 0.01 ENST00000437065.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr6_+_30295036 0.01 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr12_+_60058458 0.01 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr19_+_11546440 0.01 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH
protein kinase C substrate 80K-H
chrX_+_2746850 0.01 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2
glycogenin 2
chr19_+_11546093 0.01 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr14_+_74551650 0.01 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr1_-_156675564 0.01 ENST00000368220.1
CRABP2
cellular retinoic acid binding protein 2
chr11_+_123325106 0.00 ENST00000525757.1
LINC01059
long intergenic non-protein coding RNA 1059
chr19_-_3062465 0.00 ENST00000327141.4
AES
amino-terminal enhancer of split
chr16_-_75285380 0.00 ENST00000393420.6
ENST00000162330.5
BCAR1
breast cancer anti-estrogen resistance 1
chr5_-_16509101 0.00 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr11_+_17281900 0.00 ENST00000530527.1
NUCB2
nucleobindin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARD

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.1 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.0 GO:0002368 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.0 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins