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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for PPARA

Z-value: 0.52

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Transcription factors associated with PPARA

Gene Symbol Gene ID Gene Info
PPARA
ENSG00000186951.12 peroxisome proliferator activated receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARAhg19_v2_chr22_+_46546494_46546525-0.811.9e-01Click!

Activity profile of PPARA motif

Sorted Z-values of PPARA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_65337708 0.45 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr3_-_117716418 0.40 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr17_-_49021974 0.33 ENST00000501718.2
RP11-700H6.1
RP11-700H6.1
chr10_+_81065975 0.29 ENST00000446377.2
ZMIZ1
zinc finger, MIZ-type containing 1
chr11_+_73498973 0.28 ENST00000537007.1
MRPL48
mitochondrial ribosomal protein L48
chr1_-_12679171 0.26 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr9_-_35685452 0.25 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr5_-_87564620 0.24 ENST00000506536.1
ENST00000512429.1
ENST00000514135.1
ENST00000296595.6
ENST00000509387.1
TMEM161B
transmembrane protein 161B
chr1_-_85156417 0.23 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr17_+_48046671 0.22 ENST00000505318.2
DLX4
distal-less homeobox 4
chr15_+_23810903 0.21 ENST00000564592.1
MKRN3
makorin ring finger protein 3
chr1_+_46640750 0.21 ENST00000372003.1
TSPAN1
tetraspanin 1
chr14_+_32476072 0.20 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr1_+_145727681 0.19 ENST00000417171.1
ENST00000451928.2
PDZK1
PDZ domain containing 1
chr19_-_51568324 0.18 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
KLK13
kallikrein-related peptidase 13
chr16_+_58535372 0.17 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr15_+_59730348 0.17 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr19_-_4535233 0.16 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr14_-_21492251 0.15 ENST00000554398.1
NDRG2
NDRG family member 2
chr7_+_128399002 0.15 ENST00000493278.1
CALU
calumenin
chr17_-_7123021 0.15 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr16_+_53133070 0.15 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr9_-_16705069 0.15 ENST00000471301.2
BNC2
basonuclin 2
chr17_+_7533439 0.15 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr1_-_160231451 0.14 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr7_-_72936608 0.14 ENST00000404251.1
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr6_-_131299929 0.14 ENST00000531356.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr14_+_58765103 0.14 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr8_-_131028869 0.14 ENST00000518283.1
ENST00000519110.1
FAM49B
family with sequence similarity 49, member B
chr12_-_7281469 0.14 ENST00000542370.1
ENST00000266560.3
RBP5
retinol binding protein 5, cellular
chr1_+_46769303 0.14 ENST00000311672.5
UQCRH
ubiquinol-cytochrome c reductase hinge protein
chr12_+_57854274 0.13 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr8_-_131028660 0.13 ENST00000401979.2
ENST00000517654.1
ENST00000522361.1
ENST00000518167.1
FAM49B
family with sequence similarity 49, member B
chr4_+_26322409 0.13 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr15_+_82555125 0.13 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr7_-_72936531 0.12 ENST00000339594.4
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr22_+_22676808 0.12 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr9_-_34665983 0.12 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr16_+_14280742 0.12 ENST00000341243.5
MKL2
MKL/myocardin-like 2
chr11_-_64013663 0.12 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr12_-_6715808 0.12 ENST00000545584.1
CHD4
chromodomain helicase DNA binding protein 4
chr6_+_107349392 0.12 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
C6orf203
chromosome 6 open reading frame 203
chr3_-_167452262 0.12 ENST00000487947.2
PDCD10
programmed cell death 10
chr19_-_49371711 0.12 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr8_-_125486755 0.12 ENST00000499418.2
ENST00000530778.1
RNF139-AS1
RNF139 antisense RNA 1 (head to head)
chr8_+_97597148 0.12 ENST00000521590.1
SDC2
syndecan 2
chr21_-_27107198 0.11 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr17_-_7082668 0.11 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr3_-_113464906 0.11 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr8_-_131028782 0.11 ENST00000519020.1
FAM49B
family with sequence similarity 49, member B
chr11_+_73498898 0.11 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr13_+_41635617 0.11 ENST00000542082.1
WBP4
WW domain binding protein 4
chr2_-_177684007 0.11 ENST00000451851.1
AC092162.1
AC092162.1
chr4_+_106067943 0.11 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
TET2
tet methylcytosine dioxygenase 2
chr1_-_26233423 0.11 ENST00000357865.2
STMN1
stathmin 1
chr14_-_23791484 0.11 ENST00000594872.1
AL049829.1
Uncharacterized protein
chr12_-_96793142 0.11 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr20_-_35807741 0.11 ENST00000434295.1
ENST00000441008.2
ENST00000400441.3
ENST00000343811.4
MROH8
maestro heat-like repeat family member 8
chr3_-_167813132 0.11 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr7_-_140624499 0.10 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr3_-_42845922 0.10 ENST00000452906.2
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr12_-_16760195 0.10 ENST00000546281.1
ENST00000537757.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_-_72129806 0.10 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr2_-_25194476 0.10 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr1_+_32666188 0.10 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr3_-_167452298 0.10 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chr5_-_95550754 0.10 ENST00000502437.1
RP11-254I22.3
RP11-254I22.3
chr1_+_63788730 0.10 ENST00000371116.2
FOXD3
forkhead box D3
chr8_-_53626974 0.10 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr8_+_110346546 0.10 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2
enhancer of yellow 2 homolog (Drosophila)
chr14_+_21566980 0.10 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr3_-_45957088 0.10 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr1_-_204183071 0.10 ENST00000308302.3
GOLT1A
golgi transport 1A
chr12_-_95397442 0.10 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr10_+_51371390 0.10 ENST00000478381.1
ENST00000451577.2
ENST00000374098.2
ENST00000374097.2
TIMM23B
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chrX_-_108868390 0.10 ENST00000372101.2
KCNE1L
KCNE1-like
chr14_+_58765305 0.10 ENST00000445108.1
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr5_-_60139347 0.10 ENST00000511799.1
ELOVL7
ELOVL fatty acid elongase 7
chr15_+_58724184 0.10 ENST00000433326.2
LIPC
lipase, hepatic
chr1_+_29213678 0.10 ENST00000347529.3
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr22_+_23248512 0.10 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr3_-_45957534 0.10 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr1_-_205719295 0.09 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_+_45140400 0.09 ENST00000453711.1
C1orf228
chromosome 1 open reading frame 228
chr7_-_105319536 0.09 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr8_-_94928861 0.09 ENST00000607097.1
MIR378D2
microRNA 378d-2
chr5_+_140027355 0.09 ENST00000417647.2
ENST00000507593.1
ENST00000508301.1
IK
IK cytokine, down-regulator of HLA II
chr14_+_61654271 0.09 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr2_+_33701707 0.09 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr20_-_13765526 0.09 ENST00000202816.1
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr4_-_668108 0.09 ENST00000304312.4
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr21_-_27107344 0.09 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_-_91487770 0.09 ENST00000337393.5
ZNF644
zinc finger protein 644
chr3_-_122102065 0.09 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58
coiled-coil domain containing 58
chr21_-_27107283 0.09 ENST00000284971.3
ENST00000400099.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr6_-_131211534 0.09 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr10_+_26986582 0.09 ENST00000376215.5
ENST00000376203.5
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr9_-_34381536 0.09 ENST00000379126.3
ENST00000379127.1
ENST00000379133.3
C9orf24
chromosome 9 open reading frame 24
chrX_-_46187069 0.09 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr15_+_71145578 0.09 ENST00000544974.2
ENST00000558546.1
LRRC49
leucine rich repeat containing 49
chr1_-_17380630 0.09 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr6_+_31939608 0.09 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr22_+_29469100 0.09 ENST00000327813.5
ENST00000407188.1
KREMEN1
kringle containing transmembrane protein 1
chr1_-_91487806 0.08 ENST00000361321.5
ZNF644
zinc finger protein 644
chr5_+_118406796 0.08 ENST00000503802.1
DMXL1
Dmx-like 1
chr14_+_21492331 0.08 ENST00000533984.1
ENST00000532213.2
AL161668.5
AL161668.5
chr1_-_211848899 0.08 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NEK2
NIMA-related kinase 2
chr10_+_76586348 0.08 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr2_+_201936458 0.08 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr10_+_81107271 0.08 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr15_+_35838396 0.08 ENST00000501169.2
DPH6-AS1
DPH6 antisense RNA 1 (head to head)
chr2_-_198364581 0.08 ENST00000428204.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr14_-_50053081 0.08 ENST00000396020.3
ENST00000245458.6
RPS29
ribosomal protein S29
chr3_-_52002194 0.08 ENST00000466412.1
PCBP4
poly(rC) binding protein 4
chr11_+_111169565 0.08 ENST00000528846.1
COLCA2
colorectal cancer associated 2
chr16_+_85942594 0.08 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr3_+_37284668 0.08 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
GOLGA4
golgin A4
chr10_-_94050820 0.08 ENST00000265997.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr19_+_16186903 0.08 ENST00000588507.1
TPM4
tropomyosin 4
chr16_-_4588469 0.08 ENST00000588381.1
ENST00000563332.2
CDIP1
cell death-inducing p53 target 1
chr22_-_38699003 0.08 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chr14_+_23791159 0.08 ENST00000557702.1
PABPN1
poly(A) binding protein, nuclear 1
chr4_+_146560245 0.08 ENST00000541599.1
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr4_+_117220016 0.08 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)
chr1_+_68150744 0.08 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr15_+_23810853 0.08 ENST00000568252.1
MKRN3
makorin ring finger protein 3
chr19_+_1407733 0.08 ENST00000592453.1
DAZAP1
DAZ associated protein 1
chr7_+_121513143 0.08 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr2_-_165698662 0.08 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr2_-_219433014 0.08 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37
chr5_+_172332220 0.08 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr8_+_66955648 0.08 ENST00000522619.1
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr20_-_30458354 0.08 ENST00000428829.1
DUSP15
dual specificity phosphatase 15
chr14_-_92572894 0.08 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr1_+_45140360 0.08 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228
chromosome 1 open reading frame 228
chr7_-_83824449 0.07 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_+_50794947 0.07 ENST00000552445.1
LARP4
La ribonucleoprotein domain family, member 4
chr14_-_31889737 0.07 ENST00000382464.2
HEATR5A
HEAT repeat containing 5A
chr14_+_75761099 0.07 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5
RP11-293M10.5
chr7_-_123198284 0.07 ENST00000355749.2
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr3_-_141747950 0.07 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_156675564 0.07 ENST00000368220.1
CRABP2
cellular retinoic acid binding protein 2
chr8_+_94929273 0.07 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr5_+_218356 0.07 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr14_-_104387888 0.07 ENST00000286953.3
C14orf2
chromosome 14 open reading frame 2
chr12_-_48744554 0.07 ENST00000544117.2
ENST00000548932.1
ENST00000549125.1
ENST00000301042.3
ENST00000547026.1
ZNF641
zinc finger protein 641
chr10_-_65028817 0.07 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr7_+_79764104 0.07 ENST00000351004.3
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr9_-_88874519 0.07 ENST00000376001.3
ENST00000339137.3
C9orf153
chromosome 9 open reading frame 153
chr17_+_7517264 0.07 ENST00000593717.1
ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
AC007421.1
SHBG
AC007421.1
sex hormone-binding globulin
chr1_+_33439268 0.07 ENST00000594612.1
FKSG48
FKSG48
chr12_-_111926342 0.07 ENST00000389154.3
ATXN2
ataxin 2
chr14_-_24729251 0.07 ENST00000559136.1
TGM1
transglutaminase 1
chr14_+_73525229 0.07 ENST00000527432.1
ENST00000531500.1
ENST00000525321.1
ENST00000526754.1
RBM25
RNA binding motif protein 25
chr3_-_197024965 0.07 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr16_+_67563250 0.07 ENST00000566907.1
FAM65A
family with sequence similarity 65, member A
chr19_+_1407517 0.07 ENST00000336761.6
ENST00000233078.4
DAZAP1
DAZ associated protein 1
chr3_+_113667354 0.07 ENST00000491556.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr4_+_26322185 0.07 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr7_-_151433393 0.07 ENST00000492843.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr16_-_68269971 0.07 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chrX_-_109683446 0.07 ENST00000372057.1
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr3_-_71114066 0.07 ENST00000485326.2
FOXP1
forkhead box P1
chr19_-_51289436 0.07 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr2_+_230787213 0.07 ENST00000409992.1
FBXO36
F-box protein 36
chr8_-_80942139 0.07 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
MRPS28
mitochondrial ribosomal protein S28
chr2_+_219745020 0.07 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr12_+_100897130 0.07 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr8_-_100905925 0.07 ENST00000518171.1
COX6C
cytochrome c oxidase subunit VIc
chr3_+_14989186 0.07 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr5_+_162887556 0.07 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR
hyaluronan-mediated motility receptor (RHAMM)
chr8_-_131028641 0.07 ENST00000523509.1
FAM49B
family with sequence similarity 49, member B
chr9_+_103189660 0.07 ENST00000374886.3
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr3_+_159943362 0.07 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr6_+_32006042 0.07 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr1_+_222988406 0.07 ENST00000448808.1
ENST00000457636.1
ENST00000439440.1
RP11-452F19.3
RP11-452F19.3
chr5_-_79287060 0.07 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3
metaxin 3
chr6_-_149969829 0.07 ENST00000367411.2
KATNA1
katanin p60 (ATPase containing) subunit A 1
chr11_+_64008443 0.07 ENST00000309366.4
FKBP2
FK506 binding protein 2, 13kDa
chr1_+_213224572 0.07 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
RPS6KC1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr6_+_149068464 0.07 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr19_+_6739662 0.07 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10
thyroid hormone receptor interactor 10
chr8_+_63161491 0.07 ENST00000523211.1
ENST00000524201.1
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr14_+_69951457 0.07 ENST00000322564.7
PLEKHD1
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
chr7_-_151433342 0.07 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr3_-_52486841 0.07 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr11_+_64008525 0.07 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr2_+_162016827 0.07 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr15_+_82555169 0.06 ENST00000565432.1
ENST00000427381.2
FAM154B
family with sequence similarity 154, member B
chr4_-_143767428 0.06 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr7_-_91875358 0.06 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1
KRIT1, ankyrin repeat containing
chr4_+_159593418 0.06 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr12_+_27849378 0.06 ENST00000310791.2
REP15
RAB15 effector protein
chr14_+_71788096 0.06 ENST00000557151.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr2_+_114256661 0.06 ENST00000306507.5
FOXD4L1
forkhead box D4-like 1
chr4_-_100815525 0.06 ENST00000226522.8
ENST00000499666.2
LAMTOR3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr12_-_6483969 0.06 ENST00000396966.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr2_-_44223089 0.06 ENST00000447246.1
ENST00000409946.1
ENST00000409659.1
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr15_-_75017711 0.06 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr19_-_49552363 0.06 ENST00000448456.3
ENST00000355414.2
CGB8
chorionic gonadotropin, beta polypeptide 8

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.5 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.4 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.3 GO:0072554 blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.5 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:1903314 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0046449 creatinine metabolic process(GO:0046449)
0.0 0.1 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.0 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.0 0.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.0 GO:0047977 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.0 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.0 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.0 GO:0016608 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction