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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for POU6F1

Z-value: 0.86

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Transcription factors associated with POU6F1

Gene Symbol Gene ID Gene Info
ENSG00000184271.11 POU class 6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU6F1hg19_v2_chr12_-_51611477_51611612-0.029.8e-01Click!

Activity profile of POU6F1 motif

Sorted Z-values of POU6F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_32767017 0.43 ENST00000400234.1
RFPL3 antisense
chr3_-_48659193 0.39 ENST00000330862.3
transmembrane protein 89
chr15_+_80351977 0.32 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
zinc finger, AN1-type domain 6
chr13_-_52027134 0.30 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr4_-_130692631 0.27 ENST00000500092.2
ENST00000509105.1
RP11-519M16.1
chr12_-_91546926 0.26 ENST00000550758.1
decorin
chr5_+_115177178 0.25 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr6_-_110501126 0.23 ENST00000368938.1
WAS protein family, member 1
chrX_+_43515467 0.22 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr12_+_49297899 0.22 ENST00000552942.1
ENST00000320516.4
coiled-coil domain containing 65
chr15_+_80351910 0.20 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6
chr4_+_78829479 0.19 ENST00000504901.1
mitochondrial ribosomal protein L1
chr1_+_171107241 0.19 ENST00000236166.3
flavin containing monooxygenase 6 pseudogene
chr11_+_71544246 0.19 ENST00000328698.1
defensin, beta 108B
chr6_+_151646800 0.18 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chrX_-_100129320 0.17 ENST00000372966.3
NADPH oxidase 1
chr3_-_108248169 0.17 ENST00000273353.3
myosin, heavy chain 15
chr1_+_225140372 0.17 ENST00000366848.1
ENST00000439375.2
dynein, axonemal, heavy chain 14
chr16_+_15744078 0.16 ENST00000396354.1
ENST00000570727.1
nudE neurodevelopment protein 1
chr11_-_93583697 0.16 ENST00000409977.1
V-set and transmembrane domain containing 5
chr15_-_31283618 0.16 ENST00000563714.1
myotubularin related protein 10
chr14_+_39944025 0.16 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr11_+_2323236 0.15 ENST00000182290.4
tetraspanin 32
chr12_-_95397442 0.15 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr2_+_202937972 0.15 ENST00000541917.1
ENST00000295844.3
uncharacterized protein KIAA2012
chr19_-_58662139 0.14 ENST00000598312.1
zinc finger protein 329
chr18_+_52495426 0.14 ENST00000262094.5
RAB27B, member RAS oncogene family
chrY_+_14958970 0.14 ENST00000453031.1
ubiquitin specific peptidase 9, Y-linked
chr5_+_67586465 0.13 ENST00000336483.5
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_-_76912070 0.13 ENST00000395711.4
ENST00000356260.5
SDA1 domain containing 1
chr15_-_85259294 0.12 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11 homolog A (S. cerevisiae)
chr15_-_85259384 0.12 ENST00000455959.3
SEC11 homolog A (S. cerevisiae)
chr20_+_58515417 0.12 ENST00000360816.3
family with sequence similarity 217, member B
chr14_+_24970800 0.12 ENST00000555109.1
Uncharacterized protein
chr9_+_128509624 0.11 ENST00000342287.5
ENST00000373487.4
pre-B-cell leukemia homeobox 3
chr18_+_9475001 0.11 ENST00000019317.4
ralA binding protein 1
chr11_+_85339623 0.11 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
transmembrane protein 126B
chr15_-_44828838 0.10 ENST00000560750.1
EIF3J antisense RNA 1 (head to head)
chr2_+_191045562 0.10 ENST00000340623.4
chromosome 2 open reading frame 88
chr15_-_85259330 0.10 ENST00000560266.1
SEC11 homolog A (S. cerevisiae)
chr17_-_39677971 0.09 ENST00000393976.2
keratin 15
chr20_+_5987890 0.09 ENST00000378868.4
cardiolipin synthase 1
chr6_-_110501200 0.09 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WAS protein family, member 1
chr12_+_102513950 0.09 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARP1 binding protein
chr13_+_98612446 0.09 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
importin 5
chr4_-_83812157 0.08 ENST00000513323.1
SEC31 homolog A (S. cerevisiae)
chr15_+_45028520 0.08 ENST00000329464.4
tripartite motif containing 69
chr11_-_4414880 0.08 ENST00000254436.7
ENST00000543625.1
tripartite motif containing 21
chr7_-_83824169 0.08 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr22_+_31518938 0.08 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
inositol polyphosphate-5-phosphatase J
chr11_-_107729887 0.08 ENST00000525815.1
solute carrier family 35, member F2
chr9_+_131644398 0.08 ENST00000372599.3
leucine rich repeat containing 8 family, member A
chr6_-_74231444 0.07 ENST00000331523.2
ENST00000356303.2
eukaryotic translation elongation factor 1 alpha 1
chr12_-_30887948 0.07 ENST00000433722.2
caprin family member 2
chr7_+_157318477 0.07 ENST00000444154.1
AC006372.1
chr6_-_111804905 0.07 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr10_+_97803151 0.07 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
cyclin J
chr15_+_59279851 0.07 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
ring finger protein 111
chr19_-_3786354 0.07 ENST00000395040.2
ENST00000310132.6
megakaryocyte-associated tyrosine kinase
chr15_+_45028753 0.07 ENST00000338264.4
tripartite motif containing 69
chr12_-_57443886 0.06 ENST00000300119.3
myosin IA
chr10_-_94257512 0.06 ENST00000371581.5
insulin-degrading enzyme
chr4_+_106631966 0.06 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
glutathione S-transferase, C-terminal domain containing
chr13_+_49551020 0.06 ENST00000541916.1
fibronectin type III domain containing 3A
chr12_-_108954933 0.06 ENST00000431469.2
ENST00000546815.1
squamous cell carcinoma antigen recognized by T cells 3
chr15_+_45028719 0.06 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
tripartite motif containing 69
chr19_+_45116921 0.06 ENST00000402988.1
immunoglobulin superfamily, member 23
chr3_-_114343768 0.06 ENST00000393785.2
zinc finger and BTB domain containing 20
chr11_+_118398178 0.05 ENST00000302783.4
ENST00000539546.1
tetratricopeptide repeat domain 36
chr19_-_3786253 0.05 ENST00000585778.1
megakaryocyte-associated tyrosine kinase
chr16_+_19422035 0.05 ENST00000381414.4
ENST00000396229.2
transmembrane channel-like 5
chr4_+_110749143 0.05 ENST00000317735.4
retinal pigment epithelium-derived rhodopsin homolog
chr6_+_42123141 0.05 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
guanylate cyclase activator 1A (retina)
RP1-139D8.6
chr2_+_128403720 0.05 ENST00000272644.3
G protein-coupled receptor 17
chr6_-_111136513 0.04 ENST00000368911.3
cyclin-dependent kinase 19
chr12_+_54892550 0.04 ENST00000545638.2
NCK-associated protein 1-like
chr12_+_49297887 0.04 ENST00000266984.5
coiled-coil domain containing 65
chr7_-_83824449 0.04 ENST00000420047.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr10_-_43904235 0.03 ENST00000356053.3
heterogeneous nuclear ribonucleoprotein F
chr19_+_42817527 0.03 ENST00000598766.1
transmembrane protein 145
chr1_+_176432298 0.03 ENST00000367661.3
ENST00000367662.3
pappalysin 2
chr2_+_191045656 0.03 ENST00000443551.2
chromosome 2 open reading frame 88
chr4_+_123161120 0.03 ENST00000446180.1
KIAA1109
chr7_+_48494660 0.03 ENST00000411975.1
ENST00000544596.1
ATP-binding cassette, sub-family A (ABC1), member 13
chr19_+_10959043 0.03 ENST00000397820.4
chromosome 19 open reading frame 38
chr6_+_110501344 0.03 ENST00000368932.1
cell division cycle 40
chr4_+_40201954 0.03 ENST00000511121.1
ras homolog family member H
chr17_-_26972126 0.03 ENST00000528896.2
KIAA0100
chr11_-_107729504 0.03 ENST00000265836.7
solute carrier family 35, member F2
chr9_+_131644388 0.03 ENST00000372600.4
leucine rich repeat containing 8 family, member A
chr9_-_86955598 0.03 ENST00000376238.4
solute carrier family 28 (concentrative nucleoside transporter), member 3
chr6_+_50786414 0.02 ENST00000344788.3
ENST00000393655.3
ENST00000263046.4
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr7_+_141490017 0.02 ENST00000247883.4
taste receptor, type 2, member 5
chr1_-_197115818 0.02 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chrX_+_119737806 0.02 ENST00000371317.5
malignant T cell amplified sequence 1
chr1_+_225117350 0.02 ENST00000413949.2
ENST00000430092.1
ENST00000366850.3
ENST00000400952.3
ENST00000366849.1
dynein, axonemal, heavy chain 14
chr8_+_92261516 0.02 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr11_-_107729287 0.02 ENST00000375682.4
solute carrier family 35, member F2
chr2_-_166060382 0.02 ENST00000409101.3
sodium channel, voltage-gated, type III, alpha subunit
chr5_+_162864575 0.02 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr12_+_102514019 0.02 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARP1 binding protein
chr15_+_74421961 0.02 ENST00000565159.1
ENST00000567206.1
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_-_151431909 0.02 ENST00000361398.3
ENST00000271715.2
pogo transposable element with ZNF domain
chr9_+_103790991 0.01 ENST00000374874.3
Lipid phosphate phosphatase-related protein type 1
chr20_+_34129770 0.01 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC and golgi 3
chr2_-_202563414 0.01 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr16_+_19421803 0.01 ENST00000541464.1
transmembrane channel-like 5
chr20_+_58203664 0.01 ENST00000541461.1
phosphatase and actin regulator 3
chr2_+_115219171 0.01 ENST00000409163.1
dipeptidyl-peptidase 10 (non-functional)
chr2_+_102721023 0.01 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr12_+_10460417 0.01 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
killer cell lectin-like receptor subfamily D, member 1
chr10_+_18041218 0.01 ENST00000480516.1
ENST00000457860.1
TMEM236
chr8_-_10512569 0.01 ENST00000382483.3
retinitis pigmentosa 1-like 1
chr20_-_50418947 0.00 ENST00000371539.3
spalt-like transcription factor 4
chr1_-_151431647 0.00 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
pogo transposable element with ZNF domain
chr1_-_21377383 0.00 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr5_+_55147205 0.00 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
interleukin 31 receptor A
chr2_-_217560248 0.00 ENST00000233813.4
insulin-like growth factor binding protein 5
chr1_-_151431674 0.00 ENST00000531094.1
pogo transposable element with ZNF domain

Network of associatons between targets according to the STRING database.

First level regulatory network of POU6F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.5 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation