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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for POU4F2

Z-value: 0.62

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Transcription factors associated with POU4F2

Gene Symbol Gene ID Gene Info
POU4F2
ENSG00000151615.3 POU class 4 homeobox 2

Activity profile of POU4F2 motif

Sorted Z-values of POU4F2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_111136299 0.45 ENST00000457688.1
CDK19
cyclin-dependent kinase 19
chr1_-_204183071 0.35 ENST00000308302.3
GOLT1A
golgi transport 1A
chr17_+_61151306 0.34 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr14_-_51027838 0.27 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr9_-_14308004 0.20 ENST00000493697.1
NFIB
nuclear factor I/B
chr12_-_118796971 0.20 ENST00000542902.1
TAOK3
TAO kinase 3
chr7_+_142982023 0.18 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
TMEM139
transmembrane protein 139
chr13_-_34250861 0.17 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
RP11-141M1.3
chr20_-_50418947 0.15 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr12_+_64798826 0.15 ENST00000540203.1
XPOT
exportin, tRNA
chr2_+_44502630 0.14 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr10_-_21186144 0.14 ENST00000377119.1
NEBL
nebulette
chr9_-_37384431 0.14 ENST00000452923.1
RP11-397D12.4
RP11-397D12.4
chr5_+_66300464 0.14 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr11_+_31531291 0.13 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr15_-_98417780 0.13 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chrX_-_99987088 0.13 ENST00000372981.1
ENST00000263033.5
SYTL4
synaptotagmin-like 4
chr8_-_18541603 0.12 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr20_-_50418972 0.12 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr4_+_76481258 0.12 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chrX_+_139791917 0.11 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr1_-_193028426 0.11 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr11_+_73498898 0.11 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr15_+_101402041 0.11 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr12_-_118797475 0.11 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr12_+_79371565 0.11 ENST00000551304.1
SYT1
synaptotagmin I
chr11_-_96076334 0.11 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr1_-_193028632 0.10 ENST00000421683.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr8_+_97773202 0.10 ENST00000519484.1
CPQ
carboxypeptidase Q
chr19_-_10446449 0.10 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chr17_-_7832753 0.10 ENST00000303790.2
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr20_+_48909240 0.10 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr17_-_38956205 0.09 ENST00000306658.7
KRT28
keratin 28
chrX_-_106146547 0.09 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr5_-_87516448 0.09 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr1_+_40506255 0.09 ENST00000421589.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr17_-_33390667 0.09 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr1_-_31666767 0.09 ENST00000530145.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr19_+_1269324 0.08 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
CIRBP
cold inducible RNA binding protein
chr19_-_38344165 0.08 ENST00000592714.1
ENST00000587395.1
AC016582.2
AC016582.2
chr21_+_17443521 0.08 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr20_-_50419055 0.08 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr4_+_169013666 0.08 ENST00000359299.3
ANXA10
annexin A10
chr14_+_55221541 0.08 ENST00000555192.1
SAMD4A
sterile alpha motif domain containing 4A
chr5_-_58295712 0.07 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_138048682 0.07 ENST00000383180.2
NME9
NME/NM23 family member 9
chr2_-_198540751 0.07 ENST00000429081.1
RFTN2
raftlin family member 2
chr1_-_193028621 0.07 ENST00000367455.4
ENST00000367454.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr14_+_32030582 0.07 ENST00000550649.1
ENST00000281081.7
NUBPL
nucleotide binding protein-like
chr6_-_111136513 0.07 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr19_-_7698599 0.07 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr11_-_125550726 0.07 ENST00000315608.3
ENST00000530048.1
ACRV1
acrosomal vesicle protein 1
chr1_+_40506392 0.07 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr16_+_28505955 0.07 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
APOBR
apolipoprotein B receptor
chr12_+_109577202 0.06 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr10_+_95372289 0.06 ENST00000371447.3
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr8_+_97773457 0.06 ENST00000521142.1
CPQ
carboxypeptidase Q
chrX_+_133930798 0.06 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr8_-_49834299 0.06 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr14_+_23727694 0.06 ENST00000399905.1
ENST00000470456.1
C14orf164
chromosome 14 open reading frame 164
chr8_-_49833978 0.06 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr7_+_142919130 0.06 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr15_-_37393406 0.06 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr6_+_10521574 0.05 ENST00000495262.1
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr15_+_45544426 0.05 ENST00000347644.3
ENST00000560438.1
SLC28A2
solute carrier family 28 (concentrative nucleoside transporter), member 2
chr11_-_125550764 0.05 ENST00000527795.1
ACRV1
acrosomal vesicle protein 1
chr17_-_39623681 0.05 ENST00000225899.3
KRT32
keratin 32
chr6_-_111804905 0.05 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr9_-_5830768 0.04 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr6_+_49518113 0.04 ENST00000529246.2
C6orf141
chromosome 6 open reading frame 141
chr5_-_140998616 0.04 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chr5_+_154393260 0.04 ENST00000435029.4
KIF4B
kinesin family member 4B
chr4_-_123542224 0.04 ENST00000264497.3
IL21
interleukin 21
chr14_-_90085458 0.04 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr12_+_56510368 0.04 ENST00000546591.1
ENST00000501597.3
RPL41
ribosomal protein L41
chr10_+_123951957 0.03 ENST00000514539.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr3_-_79816965 0.03 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_+_54951679 0.03 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr8_-_131399110 0.03 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr1_+_193028552 0.03 ENST00000400968.2
ENST00000432079.1
TROVE2
TROVE domain family, member 2
chr2_-_70780572 0.03 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr5_-_140998481 0.03 ENST00000518047.1
DIAPH1
diaphanous-related formin 1
chr11_-_107729887 0.03 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr18_-_71959159 0.03 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr12_-_30887948 0.03 ENST00000433722.2
CAPRIN2
caprin family member 2
chr4_-_169401628 0.02 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr1_+_66820058 0.02 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr15_+_74421961 0.02 ENST00000565159.1
ENST00000567206.1
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr14_+_38033252 0.02 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr6_-_25874440 0.02 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr11_-_115127611 0.02 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr4_+_169418255 0.01 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr20_+_56136136 0.01 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr15_-_74421477 0.01 ENST00000514871.1
RP11-247C2.2
HCG2004779; Uncharacterized protein
chrX_+_68835911 0.01 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr4_-_47983519 0.01 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr4_+_169418195 0.01 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr10_-_116444371 0.01 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr12_+_53848549 0.00 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr9_-_79520989 0.00 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2
prune homolog 2 (Drosophila)
chr4_+_141264597 0.00 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr1_+_229440129 0.00 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr12_+_53848505 0.00 ENST00000552819.1
ENST00000455667.3
PCBP2
poly(rC) binding protein 2
chr2_-_158300556 0.00 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)