ISMARA results: POU1F1

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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for POU1F1

Z-value: 0.76

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Transcription factors associated with POU1F1

Gene Symbol	Gene ID	Gene Info
POU1F1 Ensembl NCBI GeneCards UniProt	ENSG00000064835.6	POU class 1 homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
POU1F1	hg19_v2_chr3_-_87325728_87325739	0.60	4.0e-01	Click!

Activity profile of POU1F1 motif

Sorted Z-values of POU1F1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_+_13141010 Show fit	0.97	ENST00000443947.1	AC011288.2 Ensembl NCBI GeneCards UniProt Show fit	AC011288.2
chr12_-_25150373 Show fit	0.83	ENST00000549828.1	C12orf77 Ensembl NCBI GeneCards UniProt Show fit	chromosome 12 open reading frame 77
chr19_-_58864848 Show fit	0.70	ENST00000263100.3	A1BG Ensembl NCBI GeneCards UniProt Show fit	alpha-1-B glycoprotein
chr12_+_78359999 Show fit	0.62	ENST00000550503.1	NAV3 Ensembl NCBI GeneCards UniProt Show fit	neuron navigator 3
chr8_-_145754428 Show fit	0.50	ENST00000527462.1 ENST00000313465.5 ENST00000524821.1	C8orf82 Ensembl NCBI GeneCards UniProt Show fit	chromosome 8 open reading frame 82
chr6_+_26104104 Show fit	0.46	ENST00000377803.2	HIST1H4C Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H4c
chr6_-_26235206 Show fit	0.44	ENST00000244534.5	HIST1H1D Ensembl NCBI GeneCards UniProt Show fit	histone cluster 1, H1d
chr19_+_52873166 Show fit	0.41	ENST00000424032.2 ENST00000600321.1 ENST00000344085.5 ENST00000597976.1 ENST00000422689.2	ZNF880 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 880
chr20_-_29896388 Show fit	0.40	ENST00000400549.1	DEFB116 Ensembl NCBI GeneCards UniProt Show fit	defensin, beta 116
chr19_+_50016411 Show fit	0.38	ENST00000426395.3 ENST00000600273.1 ENST00000599988.1	FCGRT Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, receptor, transporter, alpha

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of POU1F1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1	0.4	GO:0002590	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0	0.4	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	0.3	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.1	0.3	GO:0046092	deoxycytidine metabolic process(GO:0046092)
0.1	0.3	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0	0.3	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.3	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	0.3	GO:0034310	ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310)
0.1	0.2	GO:0061300	cerebellum vasculature development(GO:0061300)

Showing 1 to 10 of 46 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.8	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.5	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.4	GO:1990357	terminal web(GO:1990357)
0.0	0.3	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	0.2	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.0	0.2	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.2	GO:0097449	astrocyte projection(GO:0097449) growth cone filopodium(GO:1990812)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.2	GO:0031931	TORC1 complex(GO:0031931)

Showing 1 to 10 of 18 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0019770	IgG receptor activity(GO:0019770)
0.1	0.4	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1	0.4	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	0.3	GO:0016749	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1	0.3	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.1	0.3	GO:0004797	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0	0.3	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1	0.2	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
0.0	0.2	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.2	GO:0035800	deubiquitinase activator activity(GO:0035800)

Showing 1 to 10 of 29 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway

Showing 1 to 1 of 1 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Total log-likelihood	Term	Description
0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins

Showing 1 to 5 of 5 entries

Results for POU1F1

Z-value: 0.76

Motif logo

Transcription factors associated with POU1F1

Activity-expression correlation:

Activity profile of POU1F1 motif

Sorted Z-values of POU1F1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of POU1F1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: