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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for PLAG1

Z-value: 0.33

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Transcription factors associated with PLAG1

Gene Symbol Gene ID Gene Info
PLAG1
ENSG00000181690.3 PLAG1 zinc finger

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PLAG1hg19_v2_chr8_-_57123815_571238670.802.0e-01Click!

Activity profile of PLAG1 motif

Sorted Z-values of PLAG1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_12419905 0.20 ENST00000535731.1
LRP6
low density lipoprotein receptor-related protein 6
chr11_+_64053311 0.15 ENST00000540370.1
GPR137
G protein-coupled receptor 137
chr3_+_19988736 0.14 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr19_-_14201776 0.14 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr1_-_201438282 0.11 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr19_-_56048456 0.11 ENST00000413299.1
SBK2
SH3 domain binding kinase family, member 2
chr17_+_20483037 0.10 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr17_+_39968926 0.09 ENST00000585664.1
ENST00000585922.1
ENST00000429461.1
FKBP10
FK506 binding protein 10, 65 kDa
chr14_-_75079294 0.09 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr19_-_44258770 0.09 ENST00000601925.1
ENST00000602222.1
ENST00000599804.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr22_-_30642782 0.08 ENST00000249075.3
LIF
leukemia inhibitory factor
chr16_-_3030283 0.08 ENST00000572619.1
ENST00000574415.1
ENST00000440027.2
ENST00000572059.1
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
chr17_+_38375528 0.08 ENST00000583268.1
WIPF2
WAS/WASL interacting protein family, member 2
chr16_+_30671223 0.08 ENST00000568722.1
FBRS
fibrosin
chr19_+_56116771 0.08 ENST00000568956.1
ZNF865
zinc finger protein 865
chr16_+_29984962 0.08 ENST00000308893.4
TAOK2
TAO kinase 2
chr16_+_4896659 0.07 ENST00000592120.1
UBN1
ubinuclein 1
chr19_-_44258733 0.07 ENST00000597586.1
ENST00000596714.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr19_-_41220957 0.07 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
ADCK4
aarF domain containing kinase 4
chr6_+_31939608 0.07 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr17_-_56591321 0.07 ENST00000583243.1
MTMR4
myotubularin related protein 4
chr12_-_57522813 0.07 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr11_-_1619524 0.07 ENST00000412090.1
KRTAP5-2
keratin associated protein 5-2
chr17_+_48351785 0.07 ENST00000507382.1
TMEM92
transmembrane protein 92
chr6_-_33285505 0.07 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr2_+_220306745 0.06 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr7_+_75024337 0.06 ENST00000450434.1
TRIM73
tripartite motif containing 73
chr7_+_73703728 0.06 ENST00000361545.5
ENST00000223398.6
CLIP2
CAP-GLY domain containing linker protein 2
chr1_-_151138323 0.06 ENST00000368908.5
LYSMD1
LysM, putative peptidoglycan-binding, domain containing 1
chr19_-_42759300 0.06 ENST00000222329.4
ERF
Ets2 repressor factor
chr19_+_40973049 0.06 ENST00000598249.1
ENST00000338932.3
ENST00000344104.3
SPTBN4
spectrin, beta, non-erythrocytic 4
chr12_+_121163538 0.06 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr1_-_110613276 0.06 ENST00000369792.4
ALX3
ALX homeobox 3
chrX_+_153146127 0.06 ENST00000452593.1
ENST00000357566.1
LCA10
Putative lung carcinoma-associated protein 10
chr17_-_4607335 0.06 ENST00000570571.1
ENST00000575101.1
ENST00000436683.2
ENST00000574876.1
PELP1
proline, glutamate and leucine rich protein 1
chr17_+_48046671 0.06 ENST00000505318.2
DLX4
distal-less homeobox 4
chr19_+_39904168 0.05 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr11_-_72852320 0.05 ENST00000422375.1
FCHSD2
FCH and double SH3 domains 2
chr12_+_57998400 0.05 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr19_-_51054299 0.05 ENST00000599957.1
LRRC4B
leucine rich repeat containing 4B
chr19_+_41725140 0.05 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr16_+_2198604 0.05 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr4_-_38666430 0.05 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr11_-_6440283 0.05 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr14_+_79745682 0.05 ENST00000557594.1
NRXN3
neurexin 3
chr11_+_66610883 0.05 ENST00000309657.3
ENST00000524506.1
RCE1
Ras converting CAAX endopeptidase 1
chr10_-_21786179 0.05 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr11_+_65343494 0.04 ENST00000309295.4
ENST00000533237.1
EHBP1L1
EH domain binding protein 1-like 1
chr12_-_12419703 0.04 ENST00000543091.1
ENST00000261349.4
LRP6
low density lipoprotein receptor-related protein 6
chr11_-_57282349 0.04 ENST00000528450.1
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr14_-_51562037 0.04 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr5_+_10353780 0.04 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr6_-_43021437 0.04 ENST00000265348.3
CUL7
cullin 7
chr8_+_21912328 0.04 ENST00000432128.1
ENST00000443491.2
ENST00000517600.1
ENST00000523782.2
DMTN
dematin actin binding protein
chr11_-_94964210 0.04 ENST00000416495.2
ENST00000393234.1
SESN3
sestrin 3
chr10_-_75571566 0.04 ENST00000299641.4
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr3_-_52001448 0.04 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4
poly(rC) binding protein 4
chr10_-_102890883 0.04 ENST00000445873.1
TLX1NB
TLX1 neighbor
chr3_-_184971817 0.04 ENST00000440662.1
ENST00000456310.1
EHHADH
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr18_-_51750948 0.04 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr7_+_75024903 0.04 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr10_-_126849626 0.04 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr1_-_145470383 0.04 ENST00000369314.1
ENST00000369313.3
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr5_-_176936817 0.04 ENST00000502885.1
ENST00000506493.1
DOK3
docking protein 3
chr19_+_18283959 0.04 ENST00000597802.2
IFI30
interferon, gamma-inducible protein 30
chr1_-_115632035 0.04 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr16_+_31483374 0.04 ENST00000394863.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr6_-_31940065 0.04 ENST00000375349.3
ENST00000337523.5
DXO
decapping exoribonuclease
chr17_-_79805146 0.04 ENST00000415593.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr16_+_31483451 0.04 ENST00000565360.1
ENST00000361773.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chrX_+_51927919 0.03 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr9_+_2621950 0.03 ENST00000382096.1
VLDLR
very low density lipoprotein receptor
chr22_+_51112800 0.03 ENST00000414786.2
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr3_-_15374033 0.03 ENST00000253688.5
ENST00000383791.3
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chrX_-_16888276 0.03 ENST00000493145.1
RBBP7
retinoblastoma binding protein 7
chr1_-_27701307 0.03 ENST00000270879.4
ENST00000354982.2
FCN3
ficolin (collagen/fibrinogen domain containing) 3
chr2_-_74619152 0.03 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chrY_+_22737604 0.03 ENST00000361365.2
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr7_-_76039000 0.03 ENST00000275560.3
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr17_+_7462031 0.03 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr1_-_204654481 0.03 ENST00000367176.3
LRRN2
leucine rich repeat neuronal 2
chrX_+_48398053 0.03 ENST00000537536.1
ENST00000418627.1
TBC1D25
TBC1 domain family, member 25
chr1_+_154193643 0.03 ENST00000456325.1
UBAP2L
ubiquitin associated protein 2-like
chr19_+_40697514 0.03 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr1_-_212003556 0.03 ENST00000366996.1
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr4_-_57844989 0.03 ENST00000264230.4
NOA1
nitric oxide associated 1
chr6_-_43021612 0.03 ENST00000535468.1
CUL7
cullin 7
chr12_+_57522439 0.03 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr11_+_63997750 0.03 ENST00000321685.3
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr15_+_41186609 0.03 ENST00000220509.5
VPS18
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr1_-_68698222 0.02 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr16_+_31191431 0.02 ENST00000254108.7
ENST00000380244.3
ENST00000568685.1
FUS
fused in sarcoma
chr3_+_14989076 0.02 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr9_-_123476719 0.02 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr11_-_73309228 0.02 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr22_+_29469012 0.02 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr12_+_105724613 0.02 ENST00000549934.2
C12orf75
chromosome 12 open reading frame 75
chr20_+_35201857 0.02 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr15_+_90544532 0.02 ENST00000268154.4
ZNF710
zinc finger protein 710
chr12_+_58005204 0.02 ENST00000286494.4
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr6_+_31730773 0.02 ENST00000415669.2
ENST00000425424.1
SAPCD1
suppressor APC domain containing 1
chr10_-_75571341 0.02 ENST00000309979.6
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr11_-_73309112 0.02 ENST00000450446.2
FAM168A
family with sequence similarity 168, member A
chr12_+_57522258 0.02 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr1_+_202431859 0.02 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr12_+_56546363 0.02 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr22_+_19744226 0.02 ENST00000332710.4
ENST00000329705.7
ENST00000359500.3
TBX1
T-box 1
chr9_+_2621798 0.02 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr6_-_150039170 0.02 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr11_-_61062762 0.02 ENST00000335613.5
VWCE
von Willebrand factor C and EGF domains
chr22_+_29469100 0.02 ENST00000327813.5
ENST00000407188.1
KREMEN1
kringle containing transmembrane protein 1
chr4_+_55095428 0.02 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr17_-_1420006 0.01 ENST00000320345.6
ENST00000406424.4
INPP5K
inositol polyphosphate-5-phosphatase K
chr19_+_41083064 0.01 ENST00000595631.1
SHKBP1
SH3KBP1 binding protein 1
chr9_-_136004782 0.01 ENST00000393157.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr3_+_49711391 0.01 ENST00000296456.5
ENST00000449966.1
APEH
acylaminoacyl-peptide hydrolase
chr15_-_41408409 0.01 ENST00000361937.3
INO80
INO80 complex subunit
chr16_-_29910853 0.01 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr15_+_29131103 0.01 ENST00000558402.1
ENST00000558330.1
APBA2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr19_+_45844018 0.01 ENST00000585434.1
KLC3
kinesin light chain 3
chr9_-_123476612 0.01 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr12_+_79258547 0.01 ENST00000457153.2
SYT1
synaptotagmin I
chr19_-_14201507 0.01 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr10_+_24497704 0.01 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr1_-_153931052 0.01 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr2_-_85788652 0.01 ENST00000430215.3
GGCX
gamma-glutamyl carboxylase
chr6_+_106534192 0.01 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr1_-_68698197 0.01 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr19_+_41725088 0.01 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr11_-_111170526 0.01 ENST00000355430.4
COLCA1
colorectal cancer associated 1
chr10_+_102758105 0.01 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr6_+_43044003 0.01 ENST00000230419.4
ENST00000476760.1
ENST00000471863.1
ENST00000349241.2
ENST00000352931.2
ENST00000345201.2
PTK7
protein tyrosine kinase 7
chr20_+_35169885 0.01 ENST00000279022.2
ENST00000346786.2
MYL9
myosin, light chain 9, regulatory
chr4_-_114682936 0.01 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr19_+_45843994 0.01 ENST00000391946.2
KLC3
kinesin light chain 3
chr4_+_55095264 0.01 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr12_-_112819896 0.01 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECTD4
HECT domain containing E3 ubiquitin protein ligase 4
chrX_+_152599604 0.01 ENST00000370251.3
ENST00000421401.3
ZNF275
zinc finger protein 275
chr1_-_151138422 0.01 ENST00000440902.2
LYSMD1
LysM, putative peptidoglycan-binding, domain containing 1
chr17_+_30593195 0.00 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr2_-_152955537 0.00 ENST00000201943.5
ENST00000539935.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr2_-_152955213 0.00 ENST00000427385.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr15_-_43910438 0.00 ENST00000432436.1
STRC
stereocilin
chr7_-_22233442 0.00 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr10_+_24498060 0.00 ENST00000376454.3
ENST00000376452.3
KIAA1217
KIAA1217
chr15_-_41408339 0.00 ENST00000401393.3
INO80
INO80 complex subunit
chrX_+_110339439 0.00 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr16_+_2521500 0.00 ENST00000293973.1
NTN3
netrin 3
chr20_+_62716348 0.00 ENST00000349451.3
OPRL1
opiate receptor-like 1
chr2_-_74618964 0.00 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr14_-_25519095 0.00 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr14_-_25519317 0.00 ENST00000323944.5
STXBP6
syntaxin binding protein 6 (amisyn)
chr15_+_92397051 0.00 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr14_+_57857262 0.00 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of PLAG1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.0 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.0 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.0 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.1 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.0 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)