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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for PKNOX1_TGIF2

Z-value: 1.29

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
PKNOX1
ENSG00000160199.10 PBX/knotted 1 homeobox 1
TGIF2
ENSG00000118707.5 TGFB induced factor homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF2hg19_v2_chr20_+_35201993_35202050-0.954.5e-02Click!
PKNOX1hg19_v2_chr21_+_44394742_443947560.928.2e-02Click!

Activity profile of PKNOX1_TGIF2 motif

Sorted Z-values of PKNOX1_TGIF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39759154 1.00 ENST00000331982.5
IFNL2
interferon, lambda 2
chr16_-_69418553 0.84 ENST00000569542.2
TERF2
telomeric repeat binding factor 2
chr19_-_38743878 0.77 ENST00000587515.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr2_+_113321939 0.60 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr16_-_69418649 0.54 ENST00000566257.1
TERF2
telomeric repeat binding factor 2
chr2_+_191208601 0.51 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr4_-_175443943 0.49 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr2_+_29001711 0.48 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr1_+_145549203 0.47 ENST00000355594.4
ENST00000544626.1
ANKRD35
ankyrin repeat domain 35
chr17_+_39868577 0.46 ENST00000329402.3
GAST
gastrin
chr6_+_42123141 0.45 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
GUCA1A
RP1-139D8.6
guanylate cyclase activator 1A (retina)
RP1-139D8.6
chr1_+_207262881 0.45 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr9_-_130635741 0.44 ENST00000223836.10
AK1
adenylate kinase 1
chr15_-_76352069 0.44 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr8_+_11666649 0.44 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr2_-_203103185 0.43 ENST00000409205.1
SUMO1
small ubiquitin-like modifier 1
chr1_-_145715565 0.42 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chr1_-_238108575 0.42 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr10_+_28822636 0.41 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr14_-_50474238 0.40 ENST00000399206.1
C14orf182
chromosome 14 open reading frame 182
chr6_+_138188551 0.40 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr22_+_17082732 0.40 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr11_+_193065 0.39 ENST00000342878.2
SCGB1C1
secretoglobin, family 1C, member 1
chr8_-_99837856 0.38 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr6_-_31651817 0.36 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr18_-_54318353 0.35 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr7_-_156685890 0.35 ENST00000353442.5
LMBR1
limb development membrane protein 1
chr18_-_54305658 0.34 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chrX_-_101397433 0.34 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr3_-_142166846 0.33 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr17_-_39661849 0.31 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr5_-_94620239 0.31 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr15_+_36871983 0.31 ENST00000437989.2
ENST00000569302.1
C15orf41
chromosome 15 open reading frame 41
chr11_+_8932828 0.30 ENST00000530281.1
ENST00000396648.2
ENST00000534147.1
ENST00000529942.1
AKIP1
A kinase (PRKA) interacting protein 1
chr9_-_134615326 0.30 ENST00000438647.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr6_+_111195973 0.30 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr4_+_159593418 0.29 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr4_-_184241927 0.29 ENST00000323319.5
CLDN22
claudin 22
chr3_-_111852061 0.28 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr3_-_33481835 0.28 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr7_-_156685841 0.28 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chr2_-_203103281 0.27 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
SUMO1
small ubiquitin-like modifier 1
chr12_+_95611516 0.26 ENST00000436874.1
VEZT
vezatin, adherens junctions transmembrane protein
chr19_+_11909329 0.26 ENST00000323169.5
ENST00000450087.1
ZNF491
zinc finger protein 491
chr6_-_26027480 0.25 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr6_-_84418738 0.25 ENST00000519779.1
SNAP91
synaptosomal-associated protein, 91kDa
chr12_-_31882108 0.25 ENST00000281471.6
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr3_-_33482002 0.25 ENST00000283628.5
ENST00000456378.1
UBP1
upstream binding protein 1 (LBP-1a)
chr8_+_97506033 0.25 ENST00000518385.1
SDC2
syndecan 2
chr2_+_191208791 0.24 ENST00000423767.1
ENST00000451089.1
INPP1
inositol polyphosphate-1-phosphatase
chr9_+_111696664 0.23 ENST00000374624.3
ENST00000445175.1
FAM206A
family with sequence similarity 206, member A
chr12_-_21757774 0.23 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr19_+_11750566 0.23 ENST00000344893.3
ZNF833P
zinc finger protein 833, pseudogene
chr9_-_123639304 0.23 ENST00000436309.1
PHF19
PHD finger protein 19
chr5_-_65018834 0.23 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr3_+_67048721 0.23 ENST00000295568.4
ENST00000484414.1
ENST00000460576.1
ENST00000417314.2
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr5_-_154230130 0.23 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr14_-_94759408 0.22 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr11_-_67415048 0.22 ENST00000529256.1
ACY3
aspartoacylase (aminocyclase) 3
chr16_+_16484691 0.22 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr20_+_54987305 0.22 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr2_+_118846008 0.21 ENST00000245787.4
INSIG2
insulin induced gene 2
chr7_+_94536514 0.21 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr11_+_60552797 0.21 ENST00000308287.1
MS4A10
membrane-spanning 4-domains, subfamily A, member 10
chr18_-_52626622 0.21 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr14_-_94759361 0.21 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr10_-_16859442 0.20 ENST00000602389.1
ENST00000345264.5
RSU1
Ras suppressor protein 1
chr20_+_54987168 0.20 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr7_+_79765071 0.20 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr12_+_95611569 0.20 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr19_+_11877838 0.20 ENST00000357901.4
ENST00000454339.2
ZNF441
zinc finger protein 441
chr12_-_31882027 0.20 ENST00000541931.1
ENST00000535408.1
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr17_-_29151794 0.19 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr12_+_62654155 0.19 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr17_-_29151686 0.19 ENST00000544695.1
CRLF3
cytokine receptor-like factor 3
chr17_-_39661947 0.19 ENST00000590425.1
KRT13
keratin 13
chr12_-_31881944 0.19 ENST00000537562.1
ENST00000537960.1
ENST00000536761.1
ENST00000542781.1
ENST00000457428.2
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr3_-_27764190 0.19 ENST00000537516.1
EOMES
eomesodermin
chr3_-_142166904 0.19 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr18_+_3449821 0.18 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr15_+_33010175 0.18 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr2_+_66918558 0.18 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr11_-_107729887 0.17 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr21_+_30502806 0.17 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr4_+_26578293 0.17 ENST00000512840.1
TBC1D19
TBC1 domain family, member 19
chr15_-_36544450 0.17 ENST00000561394.1
RP11-184D12.1
RP11-184D12.1
chr12_+_52404270 0.17 ENST00000552049.1
ENST00000546756.1
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr8_-_128960591 0.17 ENST00000539634.1
TMEM75
transmembrane protein 75
chrX_-_39923656 0.17 ENST00000413905.1
BCOR
BCL6 corepressor
chr3_-_45837959 0.17 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr11_-_107729504 0.16 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr3_-_45838011 0.16 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr2_+_233925064 0.16 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr17_-_77967433 0.16 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr17_+_26833250 0.16 ENST00000577936.1
ENST00000579795.1
FOXN1
forkhead box N1
chr9_-_123638633 0.16 ENST00000456291.1
PHF19
PHD finger protein 19
chr3_-_182880541 0.16 ENST00000470251.1
ENST00000265598.3
LAMP3
lysosomal-associated membrane protein 3
chr2_+_198380289 0.16 ENST00000233892.4
ENST00000409916.1
MOB4
MOB family member 4, phocein
chr14_-_94857004 0.16 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr18_+_905104 0.16 ENST00000579794.1
ADCYAP1
adenylate cyclase activating polypeptide 1 (pituitary)
chr2_-_3504587 0.15 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr13_-_41837620 0.15 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
MTRF1
mitochondrial translational release factor 1
chr2_+_62900986 0.15 ENST00000405015.3
ENST00000413434.1
ENST00000426940.1
ENST00000449820.1
EHBP1
EH domain binding protein 1
chr22_-_50219548 0.15 ENST00000404034.1
BRD1
bromodomain containing 1
chr1_-_63988846 0.15 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr17_-_30228678 0.15 ENST00000261708.4
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr3_-_192445289 0.14 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr15_+_49170083 0.14 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr17_+_39405939 0.14 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr6_-_84418860 0.14 ENST00000521743.1
SNAP91
synaptosomal-associated protein, 91kDa
chr6_-_84418841 0.14 ENST00000369694.2
ENST00000195649.6
SNAP91
synaptosomal-associated protein, 91kDa
chr3_-_52488048 0.14 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr11_-_2924720 0.14 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr12_-_112847354 0.14 ENST00000550566.2
ENST00000553213.2
ENST00000424576.2
ENST00000202773.9
RPL6
ribosomal protein L6
chr14_-_94856987 0.14 ENST00000449399.3
ENST00000404814.4
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr5_+_115298165 0.14 ENST00000357872.4
AQPEP
Aminopeptidase Q
chr20_-_31124186 0.14 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr12_+_122667658 0.14 ENST00000339777.4
ENST00000425921.1
LRRC43
leucine rich repeat containing 43
chr11_+_64059464 0.14 ENST00000394525.2
KCNK4
potassium channel, subfamily K, member 4
chr1_-_22469459 0.14 ENST00000290167.6
WNT4
wingless-type MMTV integration site family, member 4
chr11_-_46867780 0.14 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5
cytoskeleton associated protein 5
chr5_-_66942617 0.13 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr12_-_121019165 0.13 ENST00000341039.2
ENST00000357500.4
POP5
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr14_-_21492113 0.13 ENST00000554094.1
NDRG2
NDRG family member 2
chr3_-_149093499 0.13 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr13_+_33160553 0.13 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr7_+_66205712 0.13 ENST00000451741.2
ENST00000442563.1
ENST00000450873.2
ENST00000284957.5
KCTD7
RABGEF1
potassium channel tetramerization domain containing 7
RAB guanine nucleotide exchange factor (GEF) 1
chr11_-_107729287 0.13 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr15_+_51200871 0.13 ENST00000560508.1
AP4E1
adaptor-related protein complex 4, epsilon 1 subunit
chr1_-_201081579 0.13 ENST00000367338.3
ENST00000362061.3
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr14_+_62037287 0.13 ENST00000556569.1
RP11-47I22.3
Uncharacterized protein
chr19_-_10764509 0.13 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr14_+_62164340 0.13 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr15_-_37392086 0.12 ENST00000561208.1
MEIS2
Meis homeobox 2
chr1_+_210406121 0.12 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr6_-_41673552 0.12 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr17_+_6916957 0.12 ENST00000547302.2
RNASEK-C17orf49
RNASEK-C17orf49 readthrough
chr2_-_18770812 0.12 ENST00000359846.2
ENST00000304081.4
ENST00000600945.1
ENST00000532967.1
ENST00000444297.2
NT5C1B
NT5C1B-RDH14
5'-nucleotidase, cytosolic IB
NT5C1B-RDH14 readthrough
chr15_+_49913175 0.12 ENST00000403028.3
DTWD1
DTW domain containing 1
chr6_+_26501449 0.12 ENST00000244513.6
BTN1A1
butyrophilin, subfamily 1, member A1
chr2_+_191208196 0.12 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr16_+_27413483 0.12 ENST00000337929.3
ENST00000564089.1
IL21R
interleukin 21 receptor
chr2_+_234668894 0.12 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UGT1A8
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr4_-_114682326 0.12 ENST00000505990.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr10_-_124768300 0.12 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr3_+_52719936 0.12 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr17_+_7621045 0.11 ENST00000570791.1
DNAH2
dynein, axonemal, heavy chain 2
chr10_-_118764862 0.11 ENST00000260777.10
KIAA1598
KIAA1598
chr5_-_132073111 0.11 ENST00000403231.1
KIF3A
kinesin family member 3A
chr2_+_223725652 0.11 ENST00000357430.3
ENST00000392066.3
ACSL3
acyl-CoA synthetase long-chain family member 3
chr7_-_91772263 0.11 ENST00000435873.1
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr5_-_55008136 0.11 ENST00000503891.1
ENST00000507109.1
SLC38A9
solute carrier family 38, member 9
chr14_-_94856951 0.11 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr11_-_111741994 0.11 ENST00000398006.2
ALG9
ALG9, alpha-1,2-mannosyltransferase
chr4_-_175443484 0.11 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr9_-_123639445 0.11 ENST00000312189.6
PHF19
PHD finger protein 19
chr9_-_99180597 0.11 ENST00000375256.4
ZNF367
zinc finger protein 367
chr8_-_141774467 0.11 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr17_-_42767092 0.11 ENST00000588687.1
CCDC43
coiled-coil domain containing 43
chr19_-_11849697 0.11 ENST00000586121.1
ENST00000431998.1
ENST00000341191.6
ENST00000545749.1
ENST00000440527.1
ZNF823
zinc finger protein 823
chr10_+_49514698 0.11 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr12_+_69186125 0.11 ENST00000399333.3
AC124890.1
HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
chr6_+_150070857 0.11 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_-_247335269 0.10 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
ZNF124
zinc finger protein 124
chr11_+_112046190 0.10 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2
beta-carotene oxygenase 2
chr19_+_9296279 0.10 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr16_+_81528948 0.10 ENST00000539778.2
CMIP
c-Maf inducing protein
chrX_-_152939252 0.10 ENST00000340888.3
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chr11_-_119247004 0.10 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr12_+_75784850 0.10 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr4_+_86396321 0.10 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr1_+_66258846 0.10 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr14_+_101359265 0.10 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr20_-_5485166 0.10 ENST00000589201.1
ENST00000379053.4
LINC00654
long intergenic non-protein coding RNA 654
chr4_+_57774042 0.10 ENST00000309042.7
REST
RE1-silencing transcription factor
chr19_-_49496557 0.10 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr7_+_100187196 0.10 ENST00000468962.1
ENST00000427939.2
FBXO24
F-box protein 24
chr2_-_74618907 0.10 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr15_-_31283798 0.10 ENST00000435680.1
ENST00000425768.1
MTMR10
myotubularin related protein 10
chr2_-_158182105 0.09 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr5_+_66124590 0.09 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr3_-_142166796 0.09 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr12_+_69004619 0.09 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B
RAP1B, member of RAS oncogene family
chr10_-_99052382 0.09 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr7_-_148580563 0.09 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr22_-_30234218 0.09 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr19_+_9938562 0.09 ENST00000586895.1
ENST00000358666.3
ENST00000590068.1
ENST00000593087.1
UBL5
ubiquitin-like 5
chr11_-_74660159 0.09 ENST00000527087.1
ENST00000321448.8
ENST00000340360.6
XRRA1
X-ray radiation resistance associated 1
chr16_+_50776021 0.09 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr21_+_30503282 0.09 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr1_-_32384693 0.09 ENST00000602683.1
ENST00000470404.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chrX_-_152939133 0.09 ENST00000370150.1
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chr4_-_140477928 0.09 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr7_+_1272522 0.09 ENST00000316333.8
UNCX
UNC homeobox
chr21_-_34144157 0.09 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr10_+_94608245 0.09 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr21_-_34143971 0.09 ENST00000290178.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr9_+_125027127 0.09 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr17_+_78518617 0.08 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr12_+_97306295 0.08 ENST00000457368.2
NEDD1
neural precursor cell expressed, developmentally down-regulated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.2 0.7 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.4 GO:2000349 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.7 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.4 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.3 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.1 0.2 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) renal vesicle induction(GO:0072034) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.2 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.2 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.7 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.0 0.3 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.3 GO:0015824 proline transport(GO:0015824)
0.0 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.0 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0039008 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.0 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0043201 response to leucine(GO:0043201)
0.0 0.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.0 GO:1901558 regulation of cholesterol transporter activity(GO:0060694) response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.0 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.0 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.2 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 1.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:0019808 polyamine binding(GO:0019808)
0.1 1.4 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.5 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.7 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.1 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.1 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling