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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for OLIG2_NEUROD1_ATOH1
Z-value: 0.81
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Transcription factors associated with OLIG2_NEUROD1_ATOH1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NEUROD1 | hg19_v2_chr2_-_182545603_182545603 | -0.85 | 1.5e-01 | Click! |
| ATOH1 | hg19_v2_chr4_+_94750014_94750042 | -0.59 | 4.1e-01 | Click! |
| OLIG2 | hg19_v2_chr21_+_34398153_34398250 | -0.03 | 9.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_149785236 Show fit | 0.65 |
ENST00000331491.1
|
histone cluster 2, H3d |
|
| chr15_-_94614049 Show fit | 0.64 |
ENST00000556447.1
ENST00000555772.1 |
CTD-3049M7.1 |
|
| chr22_-_21905120 Show fit | 0.53 |
ENST00000331505.5
|
RIMS binding protein 3C |
|
| chr14_+_104710541 Show fit | 0.43 |
ENST00000419115.1
|
chromosome 14 open reading frame 144 |
|
| chr6_-_33663474 Show fit | 0.43 |
ENST00000594414.1
|
SBP1; Uncharacterized protein |
|
| chr3_+_72201910 Show fit | 0.38 |
ENST00000469178.1
ENST00000485404.1 |
long intergenic non-protein coding RNA 870 |
|
| chr7_-_150777920 Show fit | 0.36 |
ENST00000353841.2
ENST00000297532.6 |
Fas-activated serine/threonine kinase |
|
| chr1_-_149812765 Show fit | 0.36 |
ENST00000369158.1
|
histone cluster 2, H3c |
|
| chr3_-_99833333 Show fit | 0.35 |
ENST00000354552.3
ENST00000331335.5 ENST00000398326.2 |
filamin A interacting protein 1-like |
|
| chr12_-_123752624 Show fit | 0.35 |
ENST00000542174.1
ENST00000535796.1 |
cyclin-dependent kinase 2 associated protein 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of OLIG2_NEUROD1_ATOH1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.0 | 0.3 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.1 | 0.2 | GO:0014734 | skeletal muscle hypertrophy(GO:0014734) |
| 0.1 | 0.2 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.1 | 0.2 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 0.1 | 0.2 | GO:0042137 | sequestering of neurotransmitter(GO:0042137) |
| 0.1 | 0.2 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.0 | 0.2 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 0.0 | 0.2 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
| 0.0 | 0.2 | GO:0036378 | calcitriol biosynthetic process from calciol(GO:0036378) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 0.3 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.2 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.0 | 0.2 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.0 | 0.1 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
| 0.0 | 0.1 | GO:0000814 | ESCRT II complex(GO:0000814) |
| 0.0 | 0.1 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.0 | 0.1 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.1 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.8 | GO:0033867 | Fas-activated serine/threonine kinase activity(GO:0033867) |
| 0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.2 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 0.1 | 0.2 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.1 | 0.2 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.0 | 0.2 | GO:0030343 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.0 | 0.2 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.0 | 0.2 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.0 | 0.2 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.0 | 0.2 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 0.3 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |