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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NR4A3

Z-value: 0.99

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Transcription factors associated with NR4A3

Gene Symbol Gene ID Gene Info
ENSG00000119508.13 nuclear receptor subfamily 4 group A member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A3hg19_v2_chr9_+_102584128_102584144-0.643.6e-01Click!

Activity profile of NR4A3 motif

Sorted Z-values of NR4A3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_145752390 0.92 ENST00000529415.2
ENST00000533758.1
leucine rich repeat containing 24
chr14_-_23791484 0.87 ENST00000594872.1
Uncharacterized protein
chr16_+_691792 0.81 ENST00000307650.4
family with sequence similarity 195, member A
chr19_+_6372444 0.60 ENST00000245812.3
alkB, alkylation repair homolog 7 (E. coli)
chr6_-_43197189 0.52 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr11_+_66624527 0.52 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr8_-_131028782 0.51 ENST00000519020.1
family with sequence similarity 49, member B
chr11_-_45939565 0.51 ENST00000525192.1
ENST00000378750.5
peroxisomal biogenesis factor 16
chr15_-_75199213 0.51 ENST00000562698.1
family with sequence similarity 219, member B
chr11_-_45939374 0.50 ENST00000533151.1
ENST00000241041.3
peroxisomal biogenesis factor 16
chr11_+_64073699 0.49 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr1_-_12679171 0.47 ENST00000606790.1
RP11-474O21.5
chr7_+_7222157 0.46 ENST00000419721.1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr17_-_7307358 0.45 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr19_+_34287174 0.42 ENST00000587559.1
ENST00000588637.1
potassium channel tetramerization domain containing 15
chr8_-_145550337 0.42 ENST00000531896.1
diacylglycerol O-acyltransferase 1
chr7_-_105926058 0.40 ENST00000417537.1
nicotinamide phosphoribosyltransferase
chr4_-_1723040 0.38 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
transmembrane protein 129
chr12_+_121163538 0.37 ENST00000242592.4
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr7_-_150777874 0.37 ENST00000540185.1
Fas-activated serine/threonine kinase
chr19_-_49339080 0.36 ENST00000595764.1
hydroxysteroid (17-beta) dehydrogenase 14
chr14_+_35451880 0.36 ENST00000554803.1
ENST00000555746.1
signal recognition particle 54kDa
chr1_+_16085263 0.36 ENST00000483633.2
ENST00000502739.1
ENST00000431771.2
filamin binding LIM protein 1
chr7_+_13141010 0.35 ENST00000443947.1
AC011288.2
chr9_+_139746792 0.34 ENST00000317446.2
ENST00000445819.1
MAM domain containing 4
chr14_-_102976135 0.34 ENST00000560748.1
ankyrin repeat domain 9
chr14_-_23288930 0.34 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_-_144897138 0.34 ENST00000377533.3
scribbled planar cell polarity protein
chr11_+_66059339 0.33 ENST00000327259.4
transmembrane protein 151A
chr11_+_63742050 0.33 ENST00000314133.3
ENST00000535431.1
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr17_+_79679369 0.33 ENST00000350690.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr1_+_16083098 0.32 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr12_+_121163602 0.32 ENST00000411593.2
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr19_-_10444188 0.31 ENST00000293677.6
ribonucleoprotein, PTB-binding 1
chr4_-_40632757 0.30 ENST00000511902.1
ENST00000505220.1
RNA binding motif protein 47
chr14_+_74035763 0.29 ENST00000238651.5
acyl-CoA thioesterase 2
chr22_+_30821732 0.29 ENST00000355143.4
mitochondrial fission process 1
chr22_-_27620603 0.29 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
chr11_+_63993738 0.29 ENST00000441250.2
ENST00000279206.3
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr11_-_118272610 0.29 ENST00000534438.1
Uncharacterized protein
chr11_+_57508825 0.29 ENST00000534355.1
chromosome 11 open reading frame 31
chr10_-_76995675 0.28 ENST00000469299.1
catechol-O-methyltransferase domain containing 1
chr20_-_36156125 0.28 ENST00000397135.1
ENST00000397137.1
bladder cancer associated protein
chr19_+_35810164 0.28 ENST00000598537.1
CD22 molecule
chr11_+_57559005 0.27 ENST00000534647.1
catenin (cadherin-associated protein), delta 1
chr3_-_9994021 0.27 ENST00000411976.2
ENST00000412055.1
proline-rich transmembrane protein 3
chr19_-_49552363 0.26 ENST00000448456.3
ENST00000355414.2
chorionic gonadotropin, beta polypeptide 8
chr16_-_2581409 0.26 ENST00000567119.1
ENST00000565480.1
ENST00000382350.1
cementum protein 1
chr7_-_74489609 0.26 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
Williams-Beuren syndrome chromosome region 16
chr17_+_73606766 0.26 ENST00000578462.1
myosin XVB pseudogene
chr11_-_61659006 0.26 ENST00000278829.2
fatty acid desaturase 3
chr4_-_159094194 0.26 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr17_+_79679299 0.26 ENST00000331531.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr3_-_50605077 0.25 ENST00000426034.1
ENST00000441239.1
chromosome 3 open reading frame 18
chr7_-_150777949 0.25 ENST00000482571.1
Fas-activated serine/threonine kinase
chr22_+_50354104 0.25 ENST00000360612.4
pim-3 oncogene
chr2_+_121493717 0.25 ENST00000418323.1
GLI family zinc finger 2
chr3_-_145940214 0.25 ENST00000481701.1
phospholipid scramblase 4
chr1_+_156698743 0.24 ENST00000524343.1
ribosomal RNA adenine dimethylase domain containing 1
chr15_+_59908633 0.24 ENST00000559626.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_-_117698765 0.24 ENST00000532119.1
FXYD domain containing ion transport regulator 2
chr20_-_36156264 0.24 ENST00000445723.1
ENST00000414080.1
bladder cancer associated protein
chr16_+_2034183 0.24 ENST00000569451.1
ENST00000248114.6
ENST00000561710.1
growth factor, augmenter of liver regeneration
chr11_+_57509020 0.24 ENST00000388857.4
ENST00000528798.1
chromosome 11 open reading frame 31
chr22_+_37959647 0.24 ENST00000415670.1
CDC42 effector protein (Rho GTPase binding) 1
chr10_-_76995769 0.24 ENST00000372538.3
catechol-O-methyltransferase domain containing 1
chr19_-_633576 0.24 ENST00000588649.2
polymerase (RNA) mitochondrial (DNA directed)
chr11_+_67798363 0.23 ENST00000525628.1
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr16_-_67450325 0.23 ENST00000348579.2
zinc finger, DHHC-type containing 1
chr17_+_36858694 0.23 ENST00000563897.1
CTB-58E17.1
chr16_+_28875126 0.22 ENST00000359285.5
ENST00000538342.1
SH2B adaptor protein 1
chr7_-_17500294 0.22 ENST00000439046.1
AC019117.2
chr22_+_30115986 0.22 ENST00000216144.3
calcium binding protein 7
chr15_-_74494779 0.22 ENST00000571341.1
stimulated by retinoic acid 6
chr2_+_128175997 0.22 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
protein C (inactivator of coagulation factors Va and VIIIa)
chr6_-_31633624 0.22 ENST00000375895.2
ENST00000375900.4
G patch domain and ankyrin repeats 1
chr5_-_141703713 0.22 ENST00000511815.1
sprouty homolog 4 (Drosophila)
chr19_+_1248547 0.22 ENST00000586757.1
ENST00000300952.2
midnolin
chr12_+_113376249 0.22 ENST00000551007.1
ENST00000548514.1
2'-5'-oligoadenylate synthetase 3, 100kDa
chr16_+_29823552 0.22 ENST00000300797.6
proline-rich transmembrane protein 2
chr15_+_75335604 0.21 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr1_+_210502238 0.21 ENST00000545154.1
ENST00000537898.1
ENST00000391905.3
ENST00000545781.1
ENST00000261458.3
ENST00000308852.6
hedgehog acyltransferase
chr1_-_46769261 0.21 ENST00000343304.6
leucine rich repeat containing 41
chr12_-_6715808 0.21 ENST00000545584.1
chromodomain helicase DNA binding protein 4
chr15_+_29211570 0.21 ENST00000558804.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr22_+_29702996 0.21 ENST00000406549.3
ENST00000360113.2
ENST00000341313.6
ENST00000403764.1
ENST00000471961.1
ENST00000407854.1
growth arrest-specific 2 like 1
chr1_-_151138323 0.21 ENST00000368908.5
LysM, putative peptidoglycan-binding, domain containing 1
chr11_-_63993690 0.21 ENST00000394546.2
ENST00000541278.1
tRNA phosphotransferase 1
chr4_-_40632881 0.21 ENST00000511598.1
RNA binding motif protein 47
chr14_-_102976091 0.21 ENST00000286918.4
ankyrin repeat domain 9
chr19_+_19639670 0.21 ENST00000436027.5
YjeF N-terminal domain containing 3
chr12_+_133067157 0.21 ENST00000261673.6
fibrosin-like 1
chr17_+_79373540 0.20 ENST00000307745.7
BAH and coiled-coil domain-containing protein 1
chr9_-_136344237 0.20 ENST00000432868.1
ENST00000371899.4
solute carrier family 2 (facilitated glucose transporter), member 6
chr16_+_29823427 0.20 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
proline-rich transmembrane protein 2
chr1_+_24117627 0.20 ENST00000400061.1
lysophospholipase II
chr8_-_145018905 0.20 ENST00000398774.2
plectin
chr17_+_55173955 0.20 ENST00000576591.1
A kinase (PRKA) anchor protein 1
chr2_+_98262497 0.20 ENST00000258424.2
cytochrome c oxidase subunit Vb
chr16_+_2880254 0.20 ENST00000570670.1
zymogen granule protein 16B
chr19_+_49713991 0.20 ENST00000597316.1
transient receptor potential cation channel, subfamily M, member 4
chr22_+_45072925 0.19 ENST00000006251.7
proline rich 5 (renal)
chr2_+_120189422 0.19 ENST00000306406.4
transmembrane protein 37
chr19_-_15236470 0.19 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ilvB (bacterial acetolactate synthase)-like
chr7_-_642261 0.19 ENST00000400758.2
protein kinase, cAMP-dependent, regulatory, type I, beta
chr17_-_77924627 0.19 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1 domain family, member 16
chr1_+_160175166 0.19 ENST00000368077.1
phosphoprotein enriched in astrocytes 15
chr12_-_46121554 0.19 ENST00000609803.1
long intergenic non-protein coding RNA 938
chr19_-_41256207 0.19 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
chromosome 19 open reading frame 54
chr16_-_28937027 0.19 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chr22_+_45072958 0.18 ENST00000403581.1
proline rich 5 (renal)
chr17_+_77893135 0.18 ENST00000574526.1
ENST00000572353.1
RP11-353N14.4
chr11_+_35639735 0.18 ENST00000317811.4
four jointed box 1 (Drosophila)
chr2_-_206950996 0.18 ENST00000414320.1
INO80 complex subunit D
chr19_-_15236562 0.18 ENST00000263383.3
ilvB (bacterial acetolactate synthase)-like
chr1_+_113217309 0.18 ENST00000544796.1
ENST00000369644.1
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr19_-_50311896 0.18 ENST00000529634.2
fuzzy planar cell polarity protein
chr19_-_3062465 0.18 ENST00000327141.4
amino-terminal enhancer of split
chr9_-_140095186 0.18 ENST00000409012.4
taperin
chr7_-_150777920 0.18 ENST00000353841.2
ENST00000297532.6
Fas-activated serine/threonine kinase
chr20_+_19738792 0.17 ENST00000412571.1
RP1-122P22.2
chr16_-_2168079 0.17 ENST00000488185.2
polycystic kidney disease 1 (autosomal dominant)
chr1_+_92495528 0.17 ENST00000370383.4
epoxide hydrolase 4
chr6_-_41909466 0.17 ENST00000414200.2
cyclin D3
chr6_-_32143828 0.17 ENST00000412465.2
ENST00000375107.3
1-acylglycerol-3-phosphate O-acyltransferase 1
chr11_+_66824346 0.17 ENST00000532559.1
ras homolog family member D
chr22_-_30960876 0.17 ENST00000401975.1
ENST00000428682.1
ENST00000423299.1
galactose-3-O-sulfotransferase 1
chr17_-_4852332 0.17 ENST00000572383.1
profilin 1
chr20_-_36156293 0.17 ENST00000373537.2
ENST00000414542.2
bladder cancer associated protein
chr1_+_16083123 0.17 ENST00000510393.1
ENST00000430076.1
filamin binding LIM protein 1
chr19_-_48867171 0.17 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
transmembrane protein 143
chr17_-_46682321 0.17 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr18_+_72168325 0.16 ENST00000582666.1
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr9_-_4299874 0.16 ENST00000381971.3
ENST00000477901.1
GLIS family zinc finger 3
chrX_+_47078069 0.16 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
cyclin-dependent kinase 16
chr19_-_10679644 0.16 ENST00000393599.2
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr21_+_45773515 0.16 ENST00000397932.2
ENST00000300481.9
transient receptor potential cation channel, subfamily M, member 2
chr2_-_73460334 0.16 ENST00000258083.2
protease-associated domain containing 1
chr1_+_156698708 0.16 ENST00000519086.1
ribosomal RNA adenine dimethylase domain containing 1
chr14_-_107283278 0.16 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr16_+_81272287 0.16 ENST00000425577.2
ENST00000564552.1
beta-carotene 15,15'-monooxygenase 1
chr4_-_140527848 0.16 ENST00000608795.1
ENST00000608958.1
SET domain containing (lysine methyltransferase) 7
chr11_+_66824276 0.16 ENST00000308831.2
ras homolog family member D
chr11_-_117699413 0.16 ENST00000528014.1
FXYD domain containing ion transport regulator 2
chr4_-_40632140 0.16 ENST00000514782.1
RNA binding motif protein 47
chr9_-_130487143 0.16 ENST00000419060.1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr19_+_10196981 0.15 ENST00000591813.1
chromosome 19 open reading frame 66
chr2_+_95831529 0.15 ENST00000295210.6
ENST00000453539.2
zinc finger protein 2
chr8_-_97247759 0.15 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
ubiquinol-cytochrome c reductase binding protein
chr19_+_40697514 0.15 ENST00000253055.3
mitogen-activated protein kinase kinase kinase 10
chr9_+_35749203 0.15 ENST00000456972.2
ENST00000378078.4
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr18_+_3411595 0.15 ENST00000552383.1
TGFB-induced factor homeobox 1
chr5_+_140019004 0.15 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
transmembrane and coiled-coil domains 6
chr20_+_1246908 0.15 ENST00000381873.3
ENST00000381867.1
syntaphilin
chr12_-_109219937 0.15 ENST00000546697.1
slingshot protein phosphatase 1
chr16_-_73082274 0.15 ENST00000268489.5
zinc finger homeobox 3
chr6_-_41909561 0.15 ENST00000372991.4
cyclin D3
chr12_+_53817633 0.15 ENST00000257863.4
ENST00000550311.1
ENST00000379791.3
anti-Mullerian hormone receptor, type II
chr1_-_9811600 0.15 ENST00000435891.1
calsyntenin 1
chr12_+_50794947 0.15 ENST00000552445.1
La ribonucleoprotein domain family, member 4
chrX_-_77225135 0.15 ENST00000458128.1
phosphoglycerate mutase family member 4
chr15_-_43622736 0.15 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
leucine carboxyl methyltransferase 2
chr15_-_78112553 0.15 ENST00000562933.1
leucine rich repeat and Ig domain containing 1
chr11_-_1783633 0.15 ENST00000367196.3
cathepsin D
chr9_-_139839064 0.14 ENST00000325285.3
ENST00000428398.1
F-box and WD repeat domain containing 5
chr6_-_32144838 0.14 ENST00000395499.1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr7_+_148892557 0.14 ENST00000262085.3
zinc finger protein 282
chr19_+_7011509 0.14 ENST00000377296.3
Uncharacterized protein
chr19_+_17416457 0.14 ENST00000252602.1
mitochondrial ribosomal protein L34
chr14_-_81408063 0.14 ENST00000557411.1
centrosomal protein 128kDa
chr19_-_5624057 0.14 ENST00000590262.1
scaffold attachment factor B2
chr11_-_70507867 0.14 ENST00000412252.1
ENST00000409161.1
ENST00000409530.1
SH3 and multiple ankyrin repeat domains 2
chr1_+_24117662 0.14 ENST00000420982.1
ENST00000374505.2
lysophospholipase II
chr3_+_120315160 0.14 ENST00000485064.1
ENST00000492739.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr3_-_197300194 0.14 ENST00000358186.2
ENST00000431056.1
3-hydroxybutyrate dehydrogenase, type 1
chr12_-_2966193 0.13 ENST00000382678.3
Uncharacterized protein ENSP00000372125
chr1_+_45274154 0.13 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTB (POZ) domain containing 19
chr16_-_67969888 0.13 ENST00000574576.2
proteasome (prosome, macropain) subunit, beta type, 10
chr13_-_95364389 0.13 ENST00000376945.2
SRY (sex determining region Y)-box 21
chr20_-_17641097 0.13 ENST00000246043.4
ribosome binding protein 1
chr6_+_19837592 0.13 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr17_-_7991021 0.13 ENST00000319144.4
arachidonate 12-lipoxygenase, 12R type
chr3_-_47934234 0.13 ENST00000420772.2
microtubule-associated protein 4
chr5_+_32710736 0.13 ENST00000415685.2
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_-_226065330 0.13 ENST00000436966.1
transmembrane protein 63A
chr19_-_51289436 0.13 ENST00000562076.1
CTD-2568A17.1
chrX_-_150067272 0.13 ENST00000355149.3
ENST00000437787.2
CD99 molecule-like 2
chrX_-_150067173 0.12 ENST00000370377.3
ENST00000320893.6
CD99 molecule-like 2
chr14_+_97059070 0.12 ENST00000553378.1
ENST00000555496.1
RP11-433J8.1
chr22_+_50925213 0.12 ENST00000395733.3
ENST00000216075.6
ENST00000395732.3
myo-inositol oxygenase
chr1_-_155232221 0.12 ENST00000355379.3
secretory carrier membrane protein 3
chrX_+_120181457 0.12 ENST00000328078.1
glutamate dehydrogenase 2
chr11_-_57282349 0.12 ENST00000528450.1
solute carrier family 43 (amino acid system L transporter), member 1
chr19_-_42927251 0.12 ENST00000597001.1
lipase, hormone-sensitive
chr6_+_111580508 0.12 ENST00000368847.4
KIAA1919
chr16_+_67563250 0.12 ENST00000566907.1
family with sequence similarity 65, member A
chr11_-_61658853 0.12 ENST00000525588.1
ENST00000540820.1
fatty acid desaturase 3
chr10_+_80828774 0.12 ENST00000334512.5
zinc finger, MIZ-type containing 1
chr11_-_65429891 0.12 ENST00000527874.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr22_-_39239987 0.12 ENST00000333039.2
neuronal pentraxin receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.2 0.6 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.5 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.2 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.1 GO:0017143 insecticide metabolic process(GO:0017143)
0.1 0.2 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.2 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.4 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.6 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.1 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.1 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.4 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.0 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.7 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0016049 cell growth(GO:0016049)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:1903273 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 1.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 0.6 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.4 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.4 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.2 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.4 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) linoleoyl-CoA desaturase activity(GO:0016213) 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.0 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.0 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins