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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NR4A1

Z-value: 0.26

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Transcription factors associated with NR4A1

Gene Symbol Gene ID Gene Info
NR4A1
ENSG00000123358.15 nuclear receptor subfamily 4 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A1hg19_v2_chr12_+_52450298_52450388-0.991.1e-02Click!

Activity profile of NR4A1 motif

Sorted Z-values of NR4A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_32476072 0.15 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr14_+_21566980 0.12 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr17_+_73629500 0.11 ENST00000375215.3
SMIM5
small integral membrane protein 5
chr8_-_92053042 0.10 ENST00000520014.1
TMEM55A
transmembrane protein 55A
chr3_-_117716418 0.10 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr14_+_35591509 0.09 ENST00000604073.1
KIAA0391
KIAA0391
chrX_-_108868390 0.07 ENST00000372101.2
KCNE1L
KCNE1-like
chr16_+_53241854 0.07 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr8_+_19536083 0.07 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr2_+_162016827 0.06 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr7_-_72936608 0.05 ENST00000404251.1
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr12_+_50794947 0.05 ENST00000552445.1
LARP4
La ribonucleoprotein domain family, member 4
chr14_-_104387888 0.05 ENST00000286953.3
C14orf2
chromosome 14 open reading frame 2
chr17_-_66287257 0.05 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr17_+_9745786 0.05 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr14_+_35591020 0.05 ENST00000603611.1
KIAA0391
KIAA0391
chr5_-_87564620 0.05 ENST00000506536.1
ENST00000512429.1
ENST00000514135.1
ENST00000296595.6
ENST00000509387.1
TMEM161B
transmembrane protein 161B
chr12_-_95467267 0.05 ENST00000330677.7
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr2_+_207024306 0.05 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr14_-_101295407 0.05 ENST00000596284.1
AL117190.2
AL117190.2
chr4_+_57253672 0.04 ENST00000602927.1
RP11-646I6.5
RP11-646I6.5
chr7_-_72936531 0.04 ENST00000339594.4
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr10_+_26986582 0.04 ENST00000376215.5
ENST00000376203.5
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr4_-_89744365 0.04 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr5_-_74162605 0.04 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A
family with sequence similarity 169, member A
chr7_-_37488547 0.04 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr4_-_74088800 0.04 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr1_-_111743285 0.04 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr2_-_25194476 0.04 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr11_-_46638378 0.04 ENST00000529192.1
HARBI1
harbinger transposase derived 1
chr9_+_36572851 0.04 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr12_-_109219937 0.04 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr17_-_7123021 0.04 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr19_+_49713991 0.04 ENST00000597316.1
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr6_+_133561725 0.04 ENST00000452339.2
EYA4
eyes absent homolog 4 (Drosophila)
chr10_-_33625154 0.04 ENST00000265371.4
NRP1
neuropilin 1
chr17_-_66287310 0.04 ENST00000582867.1
SLC16A6
solute carrier family 16, member 6
chr14_-_95623607 0.04 ENST00000531162.1
ENST00000529720.1
ENST00000343455.3
DICER1
dicer 1, ribonuclease type III
chr3_+_14989186 0.04 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr2_-_178257401 0.04 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr5_-_126409159 0.03 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr8_-_92053212 0.03 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr2_+_27282134 0.03 ENST00000441931.1
AGBL5
ATP/GTP binding protein-like 5
chr2_+_162016804 0.03 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr5_+_55354822 0.03 ENST00000511861.1
CTD-2227I18.1
CTD-2227I18.1
chr14_-_35591679 0.03 ENST00000557278.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr11_+_7618413 0.03 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr12_+_32655110 0.03 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr12_+_32654965 0.03 ENST00000472289.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr15_-_42783303 0.03 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr12_+_50794891 0.03 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr14_+_69951457 0.03 ENST00000322564.7
PLEKHD1
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
chr8_+_133787586 0.03 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr7_-_105517021 0.03 ENST00000318724.4
ENST00000419735.3
ATXN7L1
ataxin 7-like 1
chr6_+_149068464 0.03 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr11_-_113577014 0.03 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5
chr3_-_113464906 0.03 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr16_+_81272287 0.03 ENST00000425577.2
ENST00000564552.1
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr7_-_99774945 0.03 ENST00000292377.2
GPC2
glypican 2
chr10_-_128359074 0.03 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr2_+_162016916 0.03 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr12_+_21679220 0.03 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr12_+_32655048 0.03 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_+_26568965 0.03 ENST00000260585.7
ENST00000447170.1
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr10_-_75634219 0.03 ENST00000305762.7
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr18_-_60986613 0.03 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr6_+_64346386 0.03 ENST00000509330.1
PHF3
PHD finger protein 3
chr6_+_31895480 0.03 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr14_+_101295638 0.03 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr12_+_96252706 0.03 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr2_+_178257372 0.03 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr2_+_234216454 0.03 ENST00000447536.1
ENST00000409110.1
SAG
S-antigen; retina and pineal gland (arrestin)
chr4_-_89744314 0.03 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr11_-_113577052 0.02 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5
transmembrane protease, serine 5
chr14_-_104387831 0.02 ENST00000557040.1
ENST00000414262.2
ENST00000555030.1
ENST00000554713.1
ENST00000553430.1
C14orf2
chromosome 14 open reading frame 2
chr5_-_142784101 0.02 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_+_31895467 0.02 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr14_-_95624227 0.02 ENST00000526495.1
DICER1
dicer 1, ribonuclease type III
chr5_+_159895275 0.02 ENST00000517927.1
MIR146A
microRNA 146a
chr1_+_236849754 0.02 ENST00000542672.1
ENST00000366578.4
ACTN2
actinin, alpha 2
chr7_-_229557 0.02 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr10_+_12110963 0.02 ENST00000263035.4
ENST00000437298.1
DHTKD1
dehydrogenase E1 and transketolase domain containing 1
chr12_+_54378849 0.02 ENST00000515593.1
HOXC10
homeobox C10
chr7_-_6048702 0.02 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr3_-_133648656 0.02 ENST00000408895.2
C3orf36
chromosome 3 open reading frame 36
chr5_-_53115506 0.02 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1
CTD-2081C10.1
chr11_+_86749035 0.02 ENST00000305494.5
ENST00000535167.1
TMEM135
transmembrane protein 135
chr1_+_66820058 0.02 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_+_138340049 0.02 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr9_-_75567962 0.02 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr5_+_35852797 0.02 ENST00000508941.1
IL7R
interleukin 7 receptor
chr10_-_75634326 0.02 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr11_+_278365 0.02 ENST00000534750.1
NLRP6
NLR family, pyrin domain containing 6
chr1_+_212738676 0.02 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr9_+_1051481 0.02 ENST00000358146.2
ENST00000259622.6
DMRT2
doublesex and mab-3 related transcription factor 2
chr17_-_38928414 0.02 ENST00000335552.4
KRT26
keratin 26
chr7_-_6048650 0.02 ENST00000382321.4
ENST00000406569.3
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr11_+_86748863 0.02 ENST00000340353.7
TMEM135
transmembrane protein 135
chr5_+_73109339 0.02 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr17_+_7123125 0.02 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL
acyl-CoA dehydrogenase, very long chain
chr1_+_2398876 0.01 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr6_-_130536774 0.01 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr1_+_61869748 0.01 ENST00000357977.5
NFIA
nuclear factor I/A
chr4_-_40632605 0.01 ENST00000514014.1
RBM47
RNA binding motif protein 47
chrX_-_48823165 0.01 ENST00000419374.1
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr2_-_44223138 0.01 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr11_-_111649015 0.01 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr5_-_142784003 0.01 ENST00000416954.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_+_29322437 0.01 ENST00000434693.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr16_+_21312170 0.01 ENST00000338573.5
ENST00000561968.1
CRYM-AS1
CRYM antisense RNA 1
chr11_+_86748957 0.01 ENST00000526733.1
ENST00000532959.1
TMEM135
transmembrane protein 135
chr6_-_152958521 0.01 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr3_+_113465866 0.01 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr12_+_58335360 0.01 ENST00000300145.3
XRCC6BP1
XRCC6 binding protein 1
chr3_-_44519131 0.01 ENST00000425708.2
ENST00000396077.2
ZNF445
zinc finger protein 445
chr12_+_54378923 0.01 ENST00000303460.4
HOXC10
homeobox C10
chr20_-_42815733 0.01 ENST00000342272.3
JPH2
junctophilin 2
chr22_-_31364187 0.01 ENST00000215862.4
ENST00000397641.3
MORC2
MORC family CW-type zinc finger 2
chr10_-_75634260 0.01 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr10_+_101542462 0.01 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr17_+_41150793 0.01 ENST00000586277.1
RPL27
ribosomal protein L27
chr15_-_41120896 0.01 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr12_+_109577202 0.01 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr2_-_207024233 0.01 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr10_-_75351088 0.01 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr5_-_142784888 0.01 ENST00000514699.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chrX_-_54824673 0.01 ENST00000218436.6
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr3_+_184037466 0.01 ENST00000441154.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chrX_+_114874727 0.01 ENST00000543070.1
PLS3
plastin 3
chr12_+_49687425 0.01 ENST00000257860.4
PRPH
peripherin
chr13_-_30881134 0.01 ENST00000380617.3
ENST00000441394.1
KATNAL1
katanin p60 subunit A-like 1
chr7_-_81399355 0.01 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_+_35591735 0.01 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
KIAA0391
chr4_+_176986978 0.01 ENST00000508596.1
ENST00000393643.2
WDR17
WD repeat domain 17
chr1_+_176432298 0.00 ENST00000367661.3
ENST00000367662.3
PAPPA2
pappalysin 2
chr5_+_127039075 0.00 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr4_-_65275162 0.00 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr2_-_207024134 0.00 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr11_+_120971882 0.00 ENST00000392793.1
TECTA
tectorin alpha
chr5_-_27038683 0.00 ENST00000511822.1
ENST00000231021.4
CDH9
cadherin 9, type 2 (T1-cadherin)
chr17_-_36499693 0.00 ENST00000342292.4
GPR179
G protein-coupled receptor 179
chr4_-_57253587 0.00 ENST00000513376.1
ENST00000602986.1
ENST00000434343.2
ENST00000451613.1
ENST00000205214.6
ENST00000502617.1
AASDH
aminoadipate-semialdehyde dehydrogenase
chr4_+_159593271 0.00 ENST00000512251.1
ENST00000511912.1
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr7_+_6048856 0.00 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
AIMP2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr19_+_13134772 0.00 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr8_+_123793633 0.00 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr4_-_89744457 0.00 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr14_-_24711470 0.00 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr18_-_60986962 0.00 ENST00000333681.4
BCL2
B-cell CLL/lymphoma 2
chr13_-_33112956 0.00 ENST00000505213.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr3_+_14989076 0.00 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr1_-_197036364 0.00 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr17_+_41150290 0.00 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chrX_+_2746850 0.00 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2
glycogenin 2
chr3_+_101443476 0.00 ENST00000327230.4
ENST00000494050.1
CEP97
centrosomal protein 97kDa
chr3_+_51741072 0.00 ENST00000395052.3
GRM2
glutamate receptor, metabotropic 2
chr20_-_44485835 0.00 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8
acyl-CoA thioesterase 8
chr7_+_99933730 0.00 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.0 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)