ISMARA results: NR2F1

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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NR2F1

Z-value: 1.84

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Transcription factors associated with NR2F1

Gene Symbol	Gene ID	Gene Info
NR2F1 Ensembl NCBI GeneCards UniProt	ENSG00000175745.7	nuclear receptor subfamily 2 group F member 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NR2F1	hg19_v2_chr5_+_92919043_92919082	0.70	3.0e-01	Click!

Activity profile of NR2F1 motif

Sorted Z-values of NR2F1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_+_76649753 Show fit	2.45	ENST00000603759.1	USO1 Ensembl NCBI GeneCards UniProt Show fit	USO1 vesicle transport factor
chr11_-_45939374 Show fit	2.13	ENST00000533151.1 ENST00000241041.3	PEX16 Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 16
chr11_-_45939565 Show fit	1.46	ENST00000525192.1 ENST00000378750.5	PEX16 Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 16
chr19_-_633576 Show fit	1.36	ENST00000588649.2	POLRMT Ensembl NCBI GeneCards UniProt Show fit	polymerase (RNA) mitochondrial (DNA directed)
chr19_+_6372444 Show fit	1.18	ENST00000245812.3	ALKBH7 Ensembl NCBI GeneCards UniProt Show fit	alkB, alkylation repair homolog 7 (E. coli)
chr11_+_57508825 Show fit	1.15	ENST00000534355.1	C11orf31 Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 31
chr11_+_64073699 Show fit	1.09	ENST00000405666.1 ENST00000468670.1	ESRRA Ensembl NCBI GeneCards UniProt Show fit	estrogen-related receptor alpha
chr11_+_66624527 Show fit	1.02	ENST00000393952.3	LRFN4 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat and fibronectin type III domain containing 4
chr7_-_1067968 Show fit	0.96	ENST00000412051.1	C7orf50 Ensembl NCBI GeneCards UniProt Show fit	chromosome 7 open reading frame 50
chr1_+_156611900 Show fit	0.95	ENST00000457777.2 ENST00000424639.1	BCAN Ensembl NCBI GeneCards UniProt Show fit	brevican

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2F1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.6	GO:0032581	ER-dependent peroxisome organization(GO:0032581)
0.1	2.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	1.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.2	1.6	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.5	1.5	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1	1.5	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.3	1.4	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	1.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	1.2	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	1.2	GO:0070830	bicellular tight junction assembly(GO:0070830)

Showing 1 to 10 of 93 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.6	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.1	3.6	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	2.1	GO:0045171	intercellular bridge(GO:0045171)
0.0	1.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.5	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	1.4	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	1.3	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	1.3	GO:0005796	Golgi lumen(GO:0005796)
0.2	1.1	GO:1990130	Iml1 complex(GO:1990130)
0.1	0.7	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)

Showing 1 to 10 of 31 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.2	GO:0008565	protein transporter activity(GO:0008565)
0.5	1.5	GO:0004730	pseudouridylate synthase activity(GO:0004730)
0.0	1.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	1.4	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	1.4	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	1.3	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	1.2	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	1.2	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1	1.0	GO:0035877	death effector domain binding(GO:0035877)
0.3	0.9	GO:0047280	nicotinamide phosphoribosyltransferase activity(GO:0047280)

Showing 1 to 10 of 61 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	PID ARF 3PATHWAY	Arf1 pathway
0.0	1.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.5	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	1.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.9	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.7	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.5	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network

Showing 1 to 10 of 10 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	1.8	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	1.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	1.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.1	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.9	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport

Showing 1 to 10 of 22 entries

Results for NR2F1

Z-value: 1.84

Motif logo

Transcription factors associated with NR2F1

Activity-expression correlation:

Activity profile of NR2F1 motif

Sorted Z-values of NR2F1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2F1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: