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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NR1H2

Z-value: 1.66

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Transcription factors associated with NR1H2

Gene Symbol Gene ID Gene Info
NR1H2
ENSG00000131408.9 nuclear receptor subfamily 1 group H member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H2hg19_v2_chr19_+_50832895_508329280.981.9e-02Click!

Activity profile of NR1H2 motif

Sorted Z-values of NR1H2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_34679725 2.24 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr16_-_11723066 1.37 ENST00000576036.1
LITAF
lipopolysaccharide-induced TNF factor
chr17_-_17726907 1.28 ENST00000423161.3
SREBF1
sterol regulatory element binding transcription factor 1
chr19_-_17622684 1.06 ENST00000596643.1
CTD-3131K8.2
CTD-3131K8.2
chr14_-_102976135 1.00 ENST00000560748.1
ANKRD9
ankyrin repeat domain 9
chr11_+_65190245 0.90 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr16_+_577697 0.80 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15
calpain 15
chr11_+_119038897 0.79 ENST00000454811.1
ENST00000449394.1
NLRX1
NLR family member X1
chr11_+_844406 0.76 ENST00000397404.1
TSPAN4
tetraspanin 4
chr19_+_34287174 0.74 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr19_-_46296011 0.72 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr19_-_38806540 0.70 ENST00000592694.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr1_+_24117627 0.69 ENST00000400061.1
LYPLA2
lysophospholipase II
chr19_-_36391434 0.68 ENST00000396901.1
ENST00000585925.1
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr20_+_34680595 0.65 ENST00000406771.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr6_+_30687978 0.64 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr8_-_48651648 0.62 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr14_-_102976091 0.61 ENST00000286918.4
ANKRD9
ankyrin repeat domain 9
chr17_+_70026795 0.61 ENST00000472655.2
ENST00000538810.1
RP11-84E24.3
long intergenic non-protein coding RNA 1152
chr11_-_62420757 0.60 ENST00000330574.2
INTS5
integrator complex subunit 5
chr19_+_7968728 0.58 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
MAP2K7
mitogen-activated protein kinase kinase 7
chr11_-_798305 0.58 ENST00000531514.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr4_-_83483094 0.56 ENST00000508701.1
ENST00000454948.3
TMEM150C
transmembrane protein 150C
chr19_-_38806560 0.56 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr7_+_2687173 0.53 ENST00000403167.1
TTYH3
tweety family member 3
chr11_+_119039069 0.51 ENST00000422249.1
NLRX1
NLR family member X1
chr8_+_142402089 0.50 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr19_-_38806390 0.50 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr14_+_23790655 0.50 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr1_+_45274154 0.50 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr17_+_77019030 0.47 ENST00000580454.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr19_+_41092680 0.47 ENST00000594298.1
ENST00000597396.1
SHKBP1
SH3KBP1 binding protein 1
chr19_-_2042065 0.45 ENST00000591588.1
ENST00000591142.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr17_+_48351785 0.44 ENST00000507382.1
TMEM92
transmembrane protein 92
chr20_+_43343886 0.43 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr7_+_56131917 0.42 ENST00000434526.2
ENST00000275607.9
ENST00000395435.2
ENST00000413952.2
ENST00000342190.6
ENST00000437307.2
ENST00000413756.1
ENST00000451338.1
SUMF2
sulfatase modifying factor 2
chr19_+_50094866 0.42 ENST00000418929.2
PRR12
proline rich 12
chr11_+_119039414 0.41 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLRX1
NLR family member X1
chr3_-_127309879 0.40 ENST00000489960.1
ENST00000490290.1
TPRA1
transmembrane protein, adipocyte asscociated 1
chr8_+_38065104 0.39 ENST00000521311.1
BAG4
BCL2-associated athanogene 4
chr1_+_24117662 0.37 ENST00000420982.1
ENST00000374505.2
LYPLA2
lysophospholipase II
chr7_-_74489609 0.37 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
WBSCR16
Williams-Beuren syndrome chromosome region 16
chr6_+_33378738 0.36 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chrX_-_2847366 0.36 ENST00000381154.1
ARSD
arylsulfatase D
chr19_+_15783879 0.35 ENST00000551607.1
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr20_+_33292068 0.35 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr3_-_127309550 0.34 ENST00000296210.7
ENST00000355552.3
TPRA1
transmembrane protein, adipocyte asscociated 1
chr21_+_43619796 0.34 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr12_-_56123444 0.32 ENST00000546457.1
ENST00000549117.1
CD63
CD63 molecule
chr16_-_2205352 0.32 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr3_-_49466686 0.32 ENST00000273598.3
ENST00000436744.2
NICN1
nicolin 1
chr3_-_51994694 0.32 ENST00000395014.2
PCBP4
poly(rC) binding protein 4
chr17_-_2169425 0.31 ENST00000570606.1
ENST00000354901.4
SMG6
SMG6 nonsense mediated mRNA decay factor
chr11_-_118789613 0.31 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr19_+_56146352 0.31 ENST00000592881.1
ZNF580
zinc finger protein 580
chr9_-_139293249 0.30 ENST00000298532.2
SNAPC4
small nuclear RNA activating complex, polypeptide 4, 190kDa
chr12_+_56511943 0.29 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
ZC3H10
ESYT1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr19_+_57631411 0.29 ENST00000254181.4
ENST00000600940.1
USP29
ubiquitin specific peptidase 29
chr17_-_17480779 0.29 ENST00000395782.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr12_+_122064398 0.29 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr1_-_55089191 0.28 ENST00000302250.2
ENST00000371304.2
FAM151A
family with sequence similarity 151, member A
chr11_+_64692143 0.28 ENST00000164133.2
ENST00000532850.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr15_+_45021183 0.28 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr17_-_65992544 0.28 ENST00000580729.1
RP11-855A2.5
RP11-855A2.5
chr2_+_27255806 0.28 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chr22_-_33968239 0.27 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr12_+_123944070 0.27 ENST00000412157.2
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr19_+_58331087 0.27 ENST00000597134.1
ENST00000593873.1
ENST00000596498.2
ENST00000603271.1
ENST00000598031.1
ENST00000316462.4
ENST00000594328.1
CTD-2583A14.10
ZNF587B
Uncharacterized protein
zinc finger protein 587B
chr12_-_56122761 0.26 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
CD63
CD63 molecule
chr19_+_17622415 0.26 ENST00000252603.2
ENST00000600923.1
PGLS
6-phosphogluconolactonase
chr20_-_32262165 0.26 ENST00000606690.1
ENST00000246190.6
ENST00000439478.1
ENST00000375238.4
NECAB3
N-terminal EF-hand calcium binding protein 3
chr14_-_59950724 0.26 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr17_-_76975925 0.26 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr20_+_19738792 0.25 ENST00000412571.1
RP1-122P22.2
RP1-122P22.2
chr19_+_16254488 0.24 ENST00000588246.1
ENST00000593031.1
HSH2D
hematopoietic SH2 domain containing
chr17_-_8151353 0.24 ENST00000315684.8
CTC1
CTS telomere maintenance complex component 1
chr15_+_96876340 0.22 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr19_-_50420918 0.22 ENST00000595761.1
NUP62
nucleoporin 62kDa
chr20_+_43343517 0.21 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chrX_-_46759138 0.21 ENST00000377879.3
CXorf31
chromosome X open reading frame 31
chr7_+_100136811 0.21 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr4_-_140216948 0.20 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr7_+_16700806 0.20 ENST00000446596.1
ENST00000438834.1
BZW2
basic leucine zipper and W2 domains 2
chr12_+_22778116 0.20 ENST00000538218.1
ETNK1
ethanolamine kinase 1
chr14_-_22005343 0.20 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr16_-_1661988 0.20 ENST00000426508.2
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr15_+_91473403 0.20 ENST00000394275.2
UNC45A
unc-45 homolog A (C. elegans)
chrX_+_1455478 0.20 ENST00000331035.4
IL3RA
interleukin 3 receptor, alpha (low affinity)
chr8_+_27182862 0.19 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr9_-_107754034 0.19 ENST00000457720.1
RP11-217B7.3
RP11-217B7.3
chr14_-_22005197 0.19 ENST00000541965.1
SALL2
spalt-like transcription factor 2
chr12_+_57998400 0.19 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr17_-_19648916 0.19 ENST00000444455.1
ENST00000439102.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr1_-_20126365 0.19 ENST00000294543.6
ENST00000375122.2
TMCO4
transmembrane and coiled-coil domains 4
chr9_+_67977438 0.19 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr17_-_26694979 0.19 ENST00000438614.1
VTN
vitronectin
chr3_+_52007693 0.18 ENST00000494478.1
ABHD14A
abhydrolase domain containing 14A
chr15_+_75498739 0.18 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr3_-_126327398 0.18 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr11_-_61596753 0.18 ENST00000448607.1
ENST00000421879.1
FADS1
fatty acid desaturase 1
chr1_+_36335351 0.18 ENST00000373206.1
AGO1
argonaute RISC catalytic component 1
chr12_+_123942188 0.18 ENST00000526639.2
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr5_-_137374288 0.17 ENST00000514310.1
FAM13B
family with sequence similarity 13, member B
chr14_-_57197224 0.17 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3
Uncharacterized protein
chr16_-_4465886 0.17 ENST00000539968.1
CORO7
coronin 7
chr2_-_74699770 0.17 ENST00000409710.1
MRPL53
mitochondrial ribosomal protein L53
chr19_+_15752088 0.17 ENST00000585846.1
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr7_-_73153161 0.17 ENST00000395147.4
ABHD11
abhydrolase domain containing 11
chr19_+_46531127 0.17 ENST00000601033.1
CTC-344H19.4
CTC-344H19.4
chr16_+_4674787 0.16 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr10_-_70287231 0.16 ENST00000609923.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr17_+_42977062 0.16 ENST00000410006.2
ENST00000357776.2
ENST00000410027.1
CCDC103
coiled-coil domain containing 103
chr14_+_77787227 0.16 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1
glutathione S-transferase zeta 1
chr16_+_29973351 0.16 ENST00000602948.1
ENST00000279396.6
ENST00000575829.2
ENST00000561899.2
TMEM219
transmembrane protein 219
chr2_+_145425573 0.16 ENST00000600064.1
ENST00000597670.1
ENST00000414256.1
ENST00000599187.1
ENST00000451774.1
ENST00000599072.1
ENST00000596589.1
ENST00000597893.1
TEX41
testis expressed 41 (non-protein coding)
chr1_-_161208013 0.15 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr11_+_827248 0.15 ENST00000527089.1
ENST00000530183.1
EFCAB4A
EF-hand calcium binding domain 4A
chr20_-_44600810 0.15 ENST00000322927.2
ENST00000426788.1
ZNF335
zinc finger protein 335
chrX_+_49020121 0.15 ENST00000415364.1
ENST00000376338.3
ENST00000425285.1
MAGIX
MAGI family member, X-linked
chr20_+_35918035 0.15 ENST00000373606.3
ENST00000397156.3
ENST00000397150.1
ENST00000397152.3
MANBAL
mannosidase, beta A, lysosomal-like
chr8_-_121457332 0.15 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr15_-_63674218 0.15 ENST00000178638.3
CA12
carbonic anhydrase XII
chr2_+_145425534 0.15 ENST00000432608.1
ENST00000597655.1
ENST00000598659.1
ENST00000600679.1
ENST00000601277.1
ENST00000451027.1
ENST00000445791.1
ENST00000596540.1
ENST00000596230.1
ENST00000594471.1
ENST00000598248.1
ENST00000597469.1
ENST00000431734.1
ENST00000595686.1
TEX41
testis expressed 41 (non-protein coding)
chr1_-_153919128 0.15 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr8_-_124749609 0.15 ENST00000262219.6
ENST00000419625.1
ANXA13
annexin A13
chr16_+_30710462 0.14 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr9_+_95909309 0.14 ENST00000366188.2
RP11-370F5.4
RP11-370F5.4
chr19_+_1026298 0.14 ENST00000263097.4
CNN2
calponin 2
chr7_+_153584166 0.14 ENST00000404039.1
DPP6
dipeptidyl-peptidase 6
chr7_-_56160625 0.14 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr6_-_31763721 0.14 ENST00000375663.3
VARS
valyl-tRNA synthetase
chr16_+_57769635 0.14 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr11_+_86748998 0.13 ENST00000525018.1
ENST00000355734.4
TMEM135
transmembrane protein 135
chr12_-_7125770 0.13 ENST00000261407.4
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr17_-_26695013 0.13 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr2_+_228029281 0.13 ENST00000396578.3
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr10_+_101491968 0.13 ENST00000370476.5
ENST00000370472.4
CUTC
cutC copper transporter
chr1_+_87595433 0.12 ENST00000469312.2
ENST00000490006.2
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr20_+_34680620 0.12 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr15_-_102285007 0.12 ENST00000560292.2
RP11-89K11.1
Uncharacterized protein
chr17_+_4675175 0.12 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr19_+_39881951 0.12 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr4_-_39640700 0.12 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr9_-_130829588 0.12 ENST00000373078.4
NAIF1
nuclear apoptosis inducing factor 1
chr16_+_53133070 0.11 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr1_-_113478603 0.11 ENST00000443580.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr12_-_118797475 0.11 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr2_-_216946500 0.11 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr3_+_9691117 0.11 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
MTMR14
myotubularin related protein 14
chr7_-_73153122 0.11 ENST00000458339.1
ABHD11
abhydrolase domain containing 11
chr17_-_15370915 0.11 ENST00000312177.6
CDRT4
CMT1A duplicated region transcript 4
chr4_-_83483360 0.11 ENST00000449862.2
TMEM150C
transmembrane protein 150C
chr20_-_48747662 0.11 ENST00000371656.2
TMEM189
transmembrane protein 189
chr1_+_24117693 0.11 ENST00000374503.3
ENST00000374502.3
LYPLA2
lysophospholipase II
chr11_+_66276550 0.11 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr22_-_38577782 0.11 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr4_+_183164574 0.11 ENST00000511685.1
TENM3
teneurin transmembrane protein 3
chr19_+_33622996 0.10 ENST00000592765.1
ENST00000361680.2
ENST00000355868.3
WDR88
WD repeat domain 88
chr11_-_798239 0.10 ENST00000531437.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr8_+_27183033 0.10 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr19_+_58361185 0.10 ENST00000339656.5
ENST00000423137.1
ZNF587
zinc finger protein 587
chr8_+_145218673 0.10 ENST00000326134.5
MROH1
maestro heat-like repeat family member 1
chr22_+_30792846 0.10 ENST00000312932.9
ENST00000428195.1
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr1_-_206671061 0.10 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr17_-_76183111 0.09 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1
thymidine kinase 1, soluble
chr14_-_22005018 0.09 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr8_-_145652336 0.09 ENST00000529182.1
ENST00000526054.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr17_-_42580738 0.09 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
GPATCH8
G patch domain containing 8
chr7_+_123485102 0.09 ENST00000488323.1
ENST00000223026.4
HYAL4
hyaluronoglucosaminidase 4
chr6_-_88038996 0.09 ENST00000525899.1
GJB7
gap junction protein, beta 7, 25kDa
chr12_-_91573132 0.09 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr10_-_127511658 0.09 ENST00000368774.1
ENST00000368778.3
UROS
uroporphyrinogen III synthase
chr22_-_36031181 0.09 ENST00000594060.1
AL049747.1
AL049747.1
chr17_-_79604075 0.08 ENST00000374747.5
ENST00000539314.1
ENST00000331134.6
NPLOC4
nuclear protein localization 4 homolog (S. cerevisiae)
chr2_-_114036488 0.08 ENST00000263335.7
ENST00000397647.3
ENST00000348715.5
ENST00000429538.3
PAX8
paired box 8
chr11_-_62521614 0.08 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr16_+_72042487 0.08 ENST00000572887.1
ENST00000219240.4
ENST00000574309.1
ENST00000576145.1
DHODH
dihydroorotate dehydrogenase (quinone)
chr1_+_201755452 0.08 ENST00000438083.1
NAV1
neuron navigator 1
chr5_-_180671172 0.08 ENST00000512805.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr19_+_15751689 0.07 ENST00000586182.2
ENST00000591058.1
ENST00000221307.8
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr2_+_73441350 0.07 ENST00000389501.4
SMYD5
SMYD family member 5
chr17_+_60457914 0.07 ENST00000305286.3
ENST00000520404.1
ENST00000518576.1
EFCAB3
EF-hand calcium binding domain 3
chr7_-_76247617 0.07 ENST00000441393.1
POMZP3
POM121 and ZP3 fusion
chr1_+_23037323 0.07 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2
EPH receptor B2
chr19_-_58427944 0.07 ENST00000312026.5
ENST00000536263.1
ENST00000598629.1
ENST00000595559.1
ENST00000597515.1
ENST00000599251.1
ENST00000598526.1
ZNF417
zinc finger protein 417
chr11_-_108338218 0.07 ENST00000525729.1
ENST00000393084.1
C11orf65
chromosome 11 open reading frame 65
chr14_-_77787198 0.07 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr19_+_35899569 0.07 ENST00000600405.1
AC002511.1
AC002511.1
chr1_+_87595497 0.06 ENST00000471417.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr12_+_22778009 0.06 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chrX_+_102631248 0.06 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_+_29467780 0.06 ENST00000395400.3
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr11_-_1606513 0.06 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr1_-_153950098 0.06 ENST00000356648.1
JTB
jumping translocation breakpoint
chr1_-_9714644 0.06 ENST00000377320.3
C1orf200
chromosome 1 open reading frame 200
chr3_-_169587621 0.06 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr11_+_86748957 0.05 ENST00000526733.1
ENST00000532959.1
TMEM135
transmembrane protein 135
chr7_-_22259845 0.05 ENST00000420196.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr11_+_61159832 0.05 ENST00000334888.5
ENST00000398979.3
TMEM216
transmembrane protein 216
chr10_-_52000307 0.05 ENST00000443575.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 1.6 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 1.8 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 1.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.6 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1 0.4 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.7 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 1.2 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.1 0.6 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.3 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.7 GO:0040016 embryonic cleavage(GO:0040016)
0.0 3.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.1 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.2 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.3 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.3 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.3 GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.6 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1 1.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.7 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.2 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 3.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 3.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 1.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide