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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NKX2-6

Z-value: 0.48

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Transcription factors associated with NKX2-6

Gene Symbol Gene ID Gene Info
NKX2-6
ENSG00000180053.6 NK2 homeobox 6

Activity profile of NKX2-6 motif

Sorted Z-values of NKX2-6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_120365866 0.39 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr6_-_131299929 0.22 ENST00000531356.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr16_-_23724518 0.21 ENST00000457008.2
ERN2
endoplasmic reticulum to nucleus signaling 2
chr2_-_121624973 0.21 ENST00000603720.1
RP11-297J22.1
RP11-297J22.1
chr13_-_44453826 0.21 ENST00000444614.3
CCDC122
coiled-coil domain containing 122
chr10_-_6019455 0.20 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
IL15RA
interleukin 15 receptor, alpha
chr1_-_1763721 0.20 ENST00000437146.1
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr13_-_30951282 0.19 ENST00000420219.1
LINC00426
long intergenic non-protein coding RNA 426
chr17_+_33914424 0.19 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr2_-_202298268 0.18 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr8_+_22414182 0.18 ENST00000524057.1
SORBS3
sorbin and SH3 domain containing 3
chr5_+_74907284 0.18 ENST00000601380.2
ANKDD1B
ankyrin repeat and death domain containing 1B
chr3_-_121379739 0.18 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr10_+_32735030 0.18 ENST00000277657.6
ENST00000362006.5
CCDC7
coiled-coil domain containing 7
chr1_-_200638964 0.18 ENST00000367348.3
ENST00000447706.2
ENST00000331314.6
DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr3_-_42003613 0.17 ENST00000414606.1
ULK4
unc-51 like kinase 4
chr5_+_78407602 0.17 ENST00000274353.5
ENST00000524080.1
BHMT
betaine--homocysteine S-methyltransferase
chr12_-_39300071 0.15 ENST00000550863.1
CPNE8
copine VIII
chr1_-_17231271 0.15 ENST00000606899.1
RP11-108M9.6
RP11-108M9.6
chr2_-_69180083 0.15 ENST00000328895.4
GKN2
gastrokine 2
chr4_+_70916119 0.14 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr10_-_6019552 0.14 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
IL15RA
interleukin 15 receptor, alpha
chr11_-_8816375 0.14 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chr10_+_121652204 0.13 ENST00000369075.3
ENST00000543134.1
SEC23IP
SEC23 interacting protein
chr12_-_89919765 0.13 ENST00000541909.1
ENST00000313546.3
POC1B
POC1 centriolar protein B
chr10_-_4720301 0.13 ENST00000449712.1
LINC00704
long intergenic non-protein coding RNA 704
chr6_-_72129806 0.13 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr17_+_41150793 0.12 ENST00000586277.1
RPL27
ribosomal protein L27
chr19_-_39881669 0.12 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr9_-_125240235 0.12 ENST00000259357.2
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr12_-_76377795 0.12 ENST00000552856.1
RP11-114H23.1
RP11-114H23.1
chr13_-_26452679 0.12 ENST00000596729.1
AL138815.2
Uncharacterized protein
chr7_+_110731062 0.12 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr8_-_82644562 0.12 ENST00000520604.1
ENST00000521742.1
ENST00000520635.1
ZFAND1
zinc finger, AN1-type domain 1
chr6_+_24775641 0.11 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr17_-_55911970 0.11 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
RP11-60A24.3
chr15_+_42694573 0.11 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)
chr1_-_78444776 0.11 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr12_+_44152740 0.11 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4
interleukin-1 receptor-associated kinase 4
chr12_-_44152551 0.10 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
PUS7L
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr5_+_173763250 0.10 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr6_+_12007897 0.10 ENST00000437559.1
RP11-456H18.2
RP11-456H18.2
chr17_+_80517216 0.10 ENST00000531030.1
ENST00000526383.2
FOXK2
forkhead box K2
chrX_-_128782722 0.10 ENST00000427399.1
APLN
apelin
chr9_+_96846740 0.09 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr4_-_129491686 0.09 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr4_+_17579110 0.09 ENST00000606142.1
LAP3
leucine aminopeptidase 3
chr7_+_121513143 0.09 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr15_-_34394008 0.09 ENST00000527822.1
ENST00000528949.1
EMC7
ER membrane protein complex subunit 7
chr8_+_99076509 0.09 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr3_+_99986036 0.09 ENST00000471098.1
TBC1D23
TBC1 domain family, member 23
chr11_-_64527425 0.09 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr6_-_110012380 0.09 ENST00000424296.2
ENST00000341338.6
ENST00000368948.2
ENST00000285397.5
AK9
adenylate kinase 9
chr1_-_198906528 0.09 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr9_+_131452239 0.09 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr3_-_160167301 0.08 ENST00000494486.1
TRIM59
tripartite motif containing 59
chr12_-_89920030 0.08 ENST00000413530.1
ENST00000547474.1
GALNT4
POC1B-GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr10_-_101841588 0.08 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr1_-_78444738 0.08 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1
chr19_-_37663572 0.08 ENST00000588354.1
ENST00000292841.5
ENST00000355533.2
ENST00000356958.4
ZNF585A
zinc finger protein 585A
chr4_-_156875003 0.08 ENST00000433477.3
CTSO
cathepsin O
chr13_+_44453969 0.08 ENST00000325686.6
LACC1
laccase (multicopper oxidoreductase) domain containing 1
chr7_-_91509972 0.08 ENST00000425936.1
MTERF
mitochondrial transcription termination factor
chr2_+_187350883 0.08 ENST00000337859.6
ZC3H15
zinc finger CCCH-type containing 15
chr2_+_87769459 0.08 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr19_-_49552006 0.08 ENST00000391869.3
CGB1
chorionic gonadotropin, beta polypeptide 1
chr3_+_171561127 0.08 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr7_+_133812052 0.08 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr7_-_107880508 0.08 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr17_+_66511224 0.08 ENST00000588178.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr11_-_65629497 0.08 ENST00000532134.1
CFL1
cofilin 1 (non-muscle)
chr19_+_7694623 0.08 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100
PET100 homolog (S. cerevisiae)
chr13_+_115000556 0.08 ENST00000252458.6
CDC16
cell division cycle 16
chr13_-_48669204 0.08 ENST00000417167.1
MED4
mediator complex subunit 4
chr5_-_59481406 0.08 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr18_-_10791648 0.08 ENST00000583325.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr3_+_100428316 0.08 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TFG
TRK-fused gene
chr13_+_24883703 0.07 ENST00000332018.4
C1QTNF9
C1q and tumor necrosis factor related protein 9
chr15_+_84841242 0.07 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr13_+_115000521 0.07 ENST00000252457.5
ENST00000375308.1
CDC16
cell division cycle 16
chr19_-_12708113 0.07 ENST00000440366.1
ZNF490
zinc finger protein 490
chr11_+_111126707 0.07 ENST00000280325.4
C11orf53
chromosome 11 open reading frame 53
chr1_+_202431859 0.07 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr2_-_180871780 0.07 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr12_-_86230315 0.07 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr13_-_48669232 0.07 ENST00000258648.2
ENST00000378586.1
MED4
mediator complex subunit 4
chr9_+_127023704 0.07 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr16_-_47493041 0.07 ENST00000565940.2
ITFG1
integrin alpha FG-GAP repeat containing 1
chr19_-_49552363 0.07 ENST00000448456.3
ENST00000355414.2
CGB8
chorionic gonadotropin, beta polypeptide 8
chr1_+_171217622 0.07 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr3_+_32726774 0.07 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10
chr2_+_102927962 0.07 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr9_+_131447342 0.06 ENST00000409104.3
SET
SET nuclear oncogene
chr11_-_111383064 0.06 ENST00000525791.1
ENST00000456861.2
ENST00000356018.2
BTG4
B-cell translocation gene 4
chr1_-_227505289 0.06 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr11_-_62521614 0.06 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr10_-_27529486 0.06 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr19_+_52074502 0.06 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175
zinc finger protein 175
chr10_-_6019984 0.06 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr4_-_14889791 0.06 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr9_-_19065082 0.06 ENST00000415524.1
HAUS6
HAUS augmin-like complex, subunit 6
chr12_-_371994 0.06 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chr20_+_13202418 0.06 ENST00000262487.4
ISM1
isthmin 1, angiogenesis inhibitor
chr14_+_31494672 0.06 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr3_+_42544084 0.06 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
VIPR1
vasoactive intestinal peptide receptor 1
chr19_-_49527590 0.06 ENST00000357383.4
CGB
chorionic gonadotropin, beta polypeptide
chr8_-_133637624 0.06 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr1_+_156338993 0.06 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr13_+_27998681 0.06 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr5_-_42825983 0.06 ENST00000506577.1
SEPP1
selenoprotein P, plasma, 1
chr17_-_49337392 0.06 ENST00000376381.2
ENST00000586178.1
MBTD1
mbt domain containing 1
chr15_-_28344439 0.05 ENST00000431101.1
ENST00000445578.1
ENST00000353809.5
ENST00000382996.2
ENST00000354638.3
OCA2
oculocutaneous albinism II
chr17_+_33914460 0.05 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr3_+_100428188 0.05 ENST00000418917.2
ENST00000490574.1
TFG
TRK-fused gene
chr7_-_91509986 0.05 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF
mitochondrial transcription termination factor
chr6_+_126102292 0.05 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr3_+_156807663 0.05 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
LINC00881
long intergenic non-protein coding RNA 881
chr6_-_80247105 0.05 ENST00000369846.4
LCA5
Leber congenital amaurosis 5
chr1_-_157069590 0.05 ENST00000454449.2
ETV3L
ets variant 3-like
chr3_+_132316081 0.05 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr17_-_34329084 0.05 ENST00000354059.4
ENST00000536149.1
CCL15
CCL14
chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chr1_-_169337176 0.05 ENST00000472647.1
ENST00000367811.3
NME7
NME/NM23 family member 7
chr14_+_50779029 0.05 ENST00000245448.6
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr1_-_48866517 0.05 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr10_-_105437909 0.05 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr15_-_55563072 0.05 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr12_-_8088871 0.05 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr9_+_97766469 0.05 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chr12_-_89919965 0.05 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr7_-_37382360 0.05 ENST00000455119.1
ELMO1
engulfment and cell motility 1
chr2_+_70142189 0.05 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr15_-_41120896 0.04 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr11_-_105892937 0.04 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr7_+_23719749 0.04 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A
family with sequence similarity 221, member A
chr8_-_62602327 0.04 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr5_-_133510456 0.04 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr3_-_127541194 0.04 ENST00000453507.2
MGLL
monoglyceride lipase
chr18_+_7754957 0.04 ENST00000400053.4
PTPRM
protein tyrosine phosphatase, receptor type, M
chr17_-_6524159 0.04 ENST00000589033.1
KIAA0753
KIAA0753
chr2_-_69870747 0.04 ENST00000409068.1
AAK1
AP2 associated kinase 1
chr17_+_61562201 0.04 ENST00000290863.6
ENST00000413513.3
ENST00000421982.2
ACE
angiotensin I converting enzyme
chr2_+_109335929 0.04 ENST00000283195.6
RANBP2
RAN binding protein 2
chr20_+_54967663 0.04 ENST00000452950.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr17_-_56606664 0.04 ENST00000580844.1
SEPT4
septin 4
chr19_-_12444306 0.04 ENST00000594577.1
ENST00000601858.1
ZNF563
zinc finger protein 563
chr19_-_40950182 0.04 ENST00000596456.1
SERTAD3
SERTA domain containing 3
chr17_-_7216939 0.04 ENST00000573684.1
GPS2
G protein pathway suppressor 2
chr1_-_115259337 0.04 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr7_+_5938351 0.04 ENST00000325974.6
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr17_-_56606705 0.04 ENST00000317268.3
SEPT4
septin 4
chr21_-_31311818 0.04 ENST00000535441.1
ENST00000309434.7
ENST00000327783.4
ENST00000389124.2
ENST00000389125.3
ENST00000399913.1
GRIK1
glutamate receptor, ionotropic, kainate 1
chr5_+_34757309 0.04 ENST00000397449.1
RAI14
retinoic acid induced 14
chr2_-_25565377 0.04 ENST00000264709.3
ENST00000406659.3
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr14_+_31494841 0.04 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr22_+_42017987 0.04 ENST00000405506.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr11_-_61687739 0.04 ENST00000531922.1
ENST00000301773.5
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr6_-_15586238 0.04 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr4_-_170924888 0.04 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr13_-_88463487 0.04 ENST00000606221.1
RP11-471M2.3
RP11-471M2.3
chr8_+_20054878 0.03 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr19_+_55897297 0.03 ENST00000431533.2
ENST00000428193.2
ENST00000558815.1
ENST00000560583.1
ENST00000560055.1
ENST00000559463.1
RPL28
ribosomal protein L28
chr2_-_175462934 0.03 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chr2_-_182521823 0.03 ENST00000410087.3
ENST00000409440.3
CERKL
ceramide kinase-like
chr11_+_93063878 0.03 ENST00000298050.3
CCDC67
coiled-coil domain containing 67
chr5_+_175487692 0.03 ENST00000510151.1
FAM153B
family with sequence similarity 153, member B
chr1_+_169337172 0.03 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1
basic leucine zipper nuclear factor 1
chr8_+_42396712 0.03 ENST00000518574.1
ENST00000417410.2
ENST00000414154.2
SMIM19
small integral membrane protein 19
chr5_-_9903938 0.03 ENST00000511616.1
CTD-2143L24.1
CTD-2143L24.1
chr8_+_42396936 0.03 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr7_-_6865826 0.03 ENST00000538180.1
CCZ1B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
chr7_+_5938386 0.03 ENST00000537980.1
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr19_-_43835582 0.03 ENST00000595748.1
CTC-490G23.2
CTC-490G23.2
chr9_+_4839762 0.03 ENST00000448872.2
ENST00000441844.1
RCL1
RNA terminal phosphate cyclase-like 1
chr14_+_100531615 0.03 ENST00000392920.3
EVL
Enah/Vasp-like
chrX_+_139791917 0.03 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr12_-_15103621 0.03 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr20_-_5100591 0.03 ENST00000379143.5
PCNA
proliferating cell nuclear antigen
chr12_+_60083118 0.03 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr12_-_56236690 0.03 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr1_-_21113105 0.03 ENST00000375000.1
ENST00000419490.1
ENST00000414993.1
ENST00000443615.1
ENST00000312239.5
HP1BP3
heterochromatin protein 1, binding protein 3
chr3_-_123339343 0.03 ENST00000578202.1
MYLK
myosin light chain kinase
chr6_-_32977345 0.03 ENST00000450833.2
ENST00000374813.1
ENST00000229829.5
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr9_+_97766409 0.03 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chrX_-_132231123 0.03 ENST00000511190.1
USP26
ubiquitin specific peptidase 26
chr12_-_56236711 0.02 ENST00000409200.3
MMP19
matrix metallopeptidase 19
chr4_-_77996032 0.02 ENST00000505609.1
CCNI
cyclin I
chr17_+_58755184 0.02 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr16_+_58783542 0.02 ENST00000500117.1
ENST00000565722.1
RP11-410D17.2
RP11-410D17.2
chr11_-_76381029 0.02 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr7_-_46736720 0.02 ENST00000451905.1
AC011294.3
Uncharacterized protein
chr4_-_79860506 0.02 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr8_+_27629459 0.02 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr20_-_271009 0.02 ENST00000382369.5
C20orf96
chromosome 20 open reading frame 96
chr7_+_75544466 0.02 ENST00000421059.1
ENST00000394893.1
ENST00000412521.1
ENST00000414186.1
POR
P450 (cytochrome) oxidoreductase
chr2_-_175462456 0.02 ENST00000409891.1
ENST00000410117.1
WIPF1
WAS/WASL interacting protein family, member 1
chr6_+_109169591 0.02 ENST00000368972.3
ENST00000392644.4
ARMC2
armadillo repeat containing 2
chr3_+_32726620 0.02 ENST00000331889.6
ENST00000328834.5
CNOT10
CCR4-NOT transcription complex, subunit 10
chr9_+_71944241 0.02 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr17_-_56606639 0.02 ENST00000579371.1
SEPT4
septin 4
chr19_-_2282167 0.02 ENST00000342063.3
C19orf35
chromosome 19 open reading frame 35

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.2 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0061565 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.0 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.0 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.0 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis