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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NKX2-1

Z-value: 0.90

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Transcription factors associated with NKX2-1

Gene Symbol Gene ID Gene Info
NKX2-1
ENSG00000136352.13 NK2 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-1hg19_v2_chr14_-_36989427_369894420.366.4e-01Click!

Activity profile of NKX2-1 motif

Sorted Z-values of NKX2-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_50148087 0.79 ENST00000601038.1
ENST00000595242.1
SCAF1
SR-related CTD-associated factor 1
chr15_+_76030311 0.65 ENST00000543887.1
AC019294.1
AC019294.1
chr1_+_180165672 0.63 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr11_-_62313090 0.56 ENST00000528508.1
ENST00000533365.1
AHNAK
AHNAK nucleoprotein
chr16_+_640055 0.53 ENST00000568586.1
ENST00000538492.1
ENST00000248139.3
RAB40C
RAB40C, member RAS oncogene family
chr16_-_67190152 0.48 ENST00000486556.1
TRADD
TNFRSF1A-associated via death domain
chr17_+_38375528 0.42 ENST00000583268.1
WIPF2
WAS/WASL interacting protein family, member 2
chr19_-_36231437 0.42 ENST00000591748.1
IGFLR1
IGF-like family receptor 1
chr6_-_27841289 0.41 ENST00000355981.2
HIST1H4L
histone cluster 1, H4l
chr5_-_172662303 0.40 ENST00000517440.1
ENST00000329198.4
NKX2-5
NK2 homeobox 5
chr19_+_36235964 0.39 ENST00000587708.2
PSENEN
presenilin enhancer gamma secretase subunit
chr15_-_43029252 0.38 ENST00000563260.1
ENST00000356231.3
CDAN1
codanin 1
chr8_+_94752349 0.38 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr6_-_42858534 0.36 ENST00000408925.2
C6orf226
chromosome 6 open reading frame 226
chr6_+_100054606 0.33 ENST00000369215.4
PRDM13
PR domain containing 13
chr3_-_49837254 0.30 ENST00000412678.2
ENST00000343366.4
ENST00000487256.1
CDHR4
cadherin-related family member 4
chr16_+_58533951 0.30 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chr19_-_46234119 0.30 ENST00000317683.3
FBXO46
F-box protein 46
chr22_-_30968839 0.29 ENST00000445645.1
ENST00000416358.1
ENST00000423371.1
ENST00000411821.1
ENST00000448604.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr8_-_144679602 0.28 ENST00000526710.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr10_-_79397547 0.28 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_-_103454876 0.25 ENST00000331272.7
FBXW4
F-box and WD repeat domain containing 4
chr15_+_89182156 0.25 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr18_+_3450161 0.25 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr19_+_751122 0.25 ENST00000215582.6
MISP
mitotic spindle positioning
chr22_-_30968813 0.25 ENST00000443111.2
ENST00000443136.1
ENST00000426220.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chrX_-_153236819 0.24 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr5_-_172662230 0.24 ENST00000424406.2
NKX2-5
NK2 homeobox 5
chr8_-_94752946 0.24 ENST00000519109.1
RBM12B
RNA binding motif protein 12B
chr19_-_10679644 0.24 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr20_-_22565101 0.23 ENST00000419308.2
FOXA2
forkhead box A2
chr21_+_33671264 0.23 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chrX_-_153237258 0.23 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr17_+_73642486 0.22 ENST00000579469.1
SMIM6
small integral membrane protein 6
chr16_+_66638003 0.21 ENST00000562357.1
ENST00000360086.4
ENST00000562707.1
ENST00000361909.4
ENST00000460097.1
ENST00000565666.1
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr16_+_66638616 0.21 ENST00000564060.1
ENST00000565922.1
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr1_-_17338386 0.21 ENST00000341676.5
ENST00000452699.1
ATP13A2
ATPase type 13A2
chr16_+_2022036 0.21 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr1_-_153518270 0.21 ENST00000354332.4
ENST00000368716.4
S100A4
S100 calcium binding protein A4
chrX_-_153236620 0.21 ENST00000369984.4
HCFC1
host cell factor C1 (VP16-accessory protein)
chr7_+_150782945 0.20 ENST00000463381.1
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr5_-_172662197 0.20 ENST00000521848.1
NKX2-5
NK2 homeobox 5
chr6_+_32121789 0.19 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr22_+_24999114 0.19 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr17_+_46048471 0.18 ENST00000578018.1
ENST00000579175.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr11_-_104827425 0.18 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr3_-_114790179 0.18 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr20_+_825275 0.18 ENST00000541082.1
FAM110A
family with sequence similarity 110, member A
chr9_+_109685630 0.18 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr19_-_39390350 0.17 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr16_+_28303804 0.17 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr17_+_76210367 0.17 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chrX_+_78003204 0.17 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr9_-_4299874 0.16 ENST00000381971.3
ENST00000477901.1
GLIS3
GLIS family zinc finger 3
chr9_-_128246769 0.16 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr18_+_72166564 0.16 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr6_-_26056695 0.15 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr17_+_46048376 0.15 ENST00000338399.4
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr1_-_156051789 0.15 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr7_+_99156249 0.15 ENST00000449244.1
ZNF655
zinc finger protein 655
chr21_+_45773515 0.15 ENST00000397932.2
ENST00000300481.9
TRPM2
transient receptor potential cation channel, subfamily M, member 2
chr8_-_144679264 0.14 ENST00000531953.1
ENST00000526133.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr7_+_99156212 0.14 ENST00000454654.1
ZNF655
zinc finger protein 655
chr3_-_139195350 0.14 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr7_+_150758642 0.14 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr16_+_57126428 0.14 ENST00000290776.8
CPNE2
copine II
chr16_+_5121814 0.14 ENST00000262374.5
ENST00000586840.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr2_-_25451065 0.13 ENST00000606328.1
RP11-458N5.1
RP11-458N5.1
chr1_-_25291475 0.13 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr16_+_66638567 0.13 ENST00000567572.1
CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr2_+_101591314 0.13 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr4_-_54930790 0.13 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr17_-_46035187 0.13 ENST00000300557.2
PRR15L
proline rich 15-like
chr1_-_68698222 0.13 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr1_+_15736359 0.12 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr17_+_73642315 0.12 ENST00000556126.2
SMIM6
small integral membrane protein 6
chr12_+_121416489 0.12 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr6_-_117747015 0.12 ENST00000368508.3
ENST00000368507.3
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr3_+_184056614 0.12 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chr3_+_187930429 0.11 ENST00000420410.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_+_32121218 0.11 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2
palmitoyl-protein thioesterase 2
chr8_-_38326119 0.11 ENST00000356207.5
ENST00000326324.6
FGFR1
fibroblast growth factor receptor 1
chr12_-_67197760 0.11 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr1_-_160232197 0.11 ENST00000419626.1
ENST00000610139.1
ENST00000475733.1
ENST00000407642.2
ENST00000368073.3
ENST00000326837.2
DCAF8
DDB1 and CUL4 associated factor 8
chr16_+_57126482 0.11 ENST00000537605.1
ENST00000535318.2
CPNE2
copine II
chr17_-_42466864 0.11 ENST00000353281.4
ENST00000262407.5
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr4_+_184826418 0.11 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr1_+_206643806 0.11 ENST00000537984.1
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr2_-_230787879 0.10 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr19_+_39390320 0.10 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr11_-_86383650 0.10 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr19_-_17622269 0.10 ENST00000595116.1
CTD-3131K8.2
CTD-3131K8.2
chr19_-_45748628 0.09 ENST00000590022.1
AC006126.4
AC006126.4
chr6_-_134373732 0.09 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr18_+_29171689 0.09 ENST00000237014.3
TTR
transthyretin
chr17_+_46048497 0.09 ENST00000583352.1
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr17_+_61086917 0.09 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr5_+_131705438 0.09 ENST00000245407.3
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr19_+_48972459 0.09 ENST00000427476.1
CYTH2
cytohesin 2
chr5_-_58335281 0.09 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_15735925 0.08 ENST00000427824.1
RP3-467K16.4
RP3-467K16.4
chr19_+_24009879 0.08 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chrX_+_22056165 0.08 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr9_-_34397800 0.08 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr12_+_6961279 0.07 ENST00000229268.8
ENST00000389231.5
ENST00000542087.1
USP5
ubiquitin specific peptidase 5 (isopeptidase T)
chr5_-_146889619 0.07 ENST00000343218.5
DPYSL3
dihydropyrimidinase-like 3
chr3_+_187930491 0.07 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr11_-_65325430 0.07 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chrX_-_70473957 0.07 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3
zinc finger, MYM-type 3
chr8_+_37654693 0.07 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr12_-_719573 0.07 ENST00000397265.3
NINJ2
ninjurin 2
chr14_-_58893876 0.07 ENST00000555097.1
ENST00000555404.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr1_+_206643787 0.07 ENST00000367120.3
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr12_+_18414446 0.07 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr17_+_76210267 0.07 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chrX_-_70474377 0.06 ENST00000373978.1
ENST00000373981.1
ZMYM3
zinc finger, MYM-type 3
chr17_-_1508379 0.06 ENST00000412517.3
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr12_-_10978957 0.06 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr7_+_99156145 0.06 ENST00000452314.1
ENST00000252713.4
ZNF655
zinc finger protein 655
chr4_+_144354644 0.05 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr1_+_55464600 0.05 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr19_+_48958766 0.05 ENST00000342291.2
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr17_+_66521936 0.05 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr10_+_63808970 0.05 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr19_+_48972265 0.05 ENST00000452733.2
CYTH2
cytohesin 2
chr1_-_153538292 0.05 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr14_+_74815116 0.05 ENST00000256362.4
VRTN
vertebrae development associated
chr22_+_24891210 0.05 ENST00000382760.2
UPB1
ureidopropionase, beta
chr19_+_39903185 0.05 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr9_-_7800067 0.05 ENST00000358227.4
TMEM261
transmembrane protein 261
chr15_-_94614049 0.05 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
CTD-3049M7.1
chr18_-_24283586 0.04 ENST00000579458.1
U3
Small nucleolar RNA U3
chr12_+_13349711 0.04 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr1_-_41487383 0.04 ENST00000302946.8
ENST00000372613.2
ENST00000439569.2
ENST00000397197.2
SLFNL1
schlafen-like 1
chr14_+_74353320 0.04 ENST00000540593.1
ENST00000555730.1
ZNF410
zinc finger protein 410
chr8_-_114389353 0.04 ENST00000343508.3
CSMD3
CUB and Sushi multiple domains 3
chr17_-_34195889 0.04 ENST00000311880.2
C17orf66
chromosome 17 open reading frame 66
chr18_-_13915530 0.04 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr17_-_34195862 0.04 ENST00000592980.1
ENST00000587626.1
C17orf66
chromosome 17 open reading frame 66
chr9_+_133986782 0.03 ENST00000372301.2
AIF1L
allograft inflammatory factor 1-like
chr8_+_145203548 0.03 ENST00000534366.1
MROH1
maestro heat-like repeat family member 1
chr10_-_98031265 0.03 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr17_+_40610862 0.03 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr8_-_144679296 0.03 ENST00000317198.6
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr9_-_5830768 0.03 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr4_+_26165074 0.03 ENST00000512351.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr19_+_1942453 0.03 ENST00000591752.1
CSNK1G2
casein kinase 1, gamma 2
chrX_+_86772787 0.02 ENST00000373114.4
KLHL4
kelch-like family member 4
chr5_+_140345820 0.02 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr8_+_77596014 0.02 ENST00000523885.1
ZFHX4
zinc finger homeobox 4
chrX_-_110655306 0.02 ENST00000371993.2
DCX
doublecortin
chr12_+_50478977 0.02 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr3_+_187930719 0.02 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_62190793 0.02 ENST00000371177.2
ENST00000606498.1
TM2D1
TM2 domain containing 1
chr1_-_92952433 0.02 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr8_+_145065521 0.02 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr11_-_65325203 0.02 ENST00000526927.1
ENST00000536982.1
LTBP3
latent transforming growth factor beta binding protein 3
chr19_+_1065922 0.01 ENST00000539243.2
HMHA1
histocompatibility (minor) HA-1
chr8_+_145065705 0.01 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr2_-_133429091 0.01 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr3_-_52029958 0.01 ENST00000294189.6
RPL29
ribosomal protein L29
chr1_-_41487415 0.01 ENST00000372611.1
SLFNL1
schlafen-like 1
chr2_-_225266802 0.01 ENST00000243806.2
FAM124B
family with sequence similarity 124B
chr17_-_8198636 0.01 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chrX_-_70474499 0.01 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr20_+_30407105 0.01 ENST00000375994.2
MYLK2
myosin light chain kinase 2
chr11_+_22688150 0.01 ENST00000454584.2
GAS2
growth arrest-specific 2
chr1_+_32930647 0.01 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chr17_+_59529743 0.01 ENST00000589003.1
ENST00000393853.4
TBX4
T-box 4
chr2_+_85646054 0.01 ENST00000389938.2
SH2D6
SH2 domain containing 6
chr2_-_152118352 0.00 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr11_-_88796803 0.00 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr6_-_41673552 0.00 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr17_-_3499125 0.00 ENST00000399759.3
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr16_-_18937072 0.00 ENST00000569122.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr1_-_182369751 0.00 ENST00000367565.1
TEDDM1
transmembrane epididymal protein 1
chr20_-_56285595 0.00 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0060927 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.2 0.7 GO:0019046 release from viral latency(GO:0019046)
0.1 0.2 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.1 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.1 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.5 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.6 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0010736 serum response element binding(GO:0010736)
0.1 0.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.2 GO:0031782 melanocortin receptor binding(GO:0031779) corticotropin hormone receptor binding(GO:0031780) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.1 0.5 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.7 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors