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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NHLH1

Z-value: 0.66

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Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
NHLH1
ENSG00000171786.5 nescient helix-loop-helix 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg19_v2_chr1_+_160336851_1603368680.772.3e-01Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_21905120 0.57 ENST00000331505.5
RIMBP3C
RIMS binding protein 3C
chr1_+_38273818 0.47 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr1_+_38273988 0.34 ENST00000446260.2
C1orf122
chromosome 1 open reading frame 122
chr2_-_287320 0.32 ENST00000401503.1
FAM150B
family with sequence similarity 150, member B
chr16_+_77246337 0.32 ENST00000563157.1
SYCE1L
synaptonemal complex central element protein 1-like
chr6_+_26156551 0.31 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr20_-_62493217 0.31 ENST00000601296.1
C20ORF135
C20ORF135
chr5_+_133562095 0.30 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr3_-_133614467 0.26 ENST00000469959.1
RAB6B
RAB6B, member RAS oncogene family
chrX_-_45710920 0.26 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr11_+_22646739 0.24 ENST00000428556.2
AC103801.2
AC103801.2
chr9_+_2017063 0.23 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_-_73184588 0.23 ENST00000395145.2
CLDN3
claudin 3
chr8_+_97506033 0.22 ENST00000518385.1
SDC2
syndecan 2
chr19_+_39989535 0.22 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr2_-_7005785 0.21 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr4_+_3768075 0.20 ENST00000509482.1
ENST00000330055.5
ADRA2C
adrenoceptor alpha 2C
chr2_-_96811170 0.20 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr10_-_103347883 0.20 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
POLL
polymerase (DNA directed), lambda
chr5_+_176873789 0.20 ENST00000323249.3
ENST00000502922.1
PRR7
proline rich 7 (synaptic)
chr15_+_90735145 0.18 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr8_-_144897549 0.18 ENST00000356994.2
ENST00000320476.3
SCRIB
scribbled planar cell polarity protein
chr17_+_73512594 0.18 ENST00000333213.6
TSEN54
TSEN54 tRNA splicing endonuclease subunit
chr22_-_21984282 0.18 ENST00000398873.3
ENST00000292778.6
YDJC
YdjC homolog (bacterial)
chr10_+_102758105 0.18 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr11_+_394145 0.17 ENST00000528036.1
PKP3
plakophilin 3
chr4_+_102268904 0.17 ENST00000527564.1
ENST00000529296.1
AP001816.1
Uncharacterized protein
chr8_-_144897138 0.17 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr2_+_85981008 0.17 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr17_+_40688190 0.17 ENST00000225927.2
NAGLU
N-acetylglucosaminidase, alpha
chr13_-_26625169 0.17 ENST00000319420.3
SHISA2
shisa family member 2
chr20_-_31172598 0.17 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr5_+_176873446 0.16 ENST00000507881.1
PRR7
proline rich 7 (synaptic)
chr1_+_180165672 0.16 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr5_-_133747551 0.16 ENST00000395009.3
CDKN2AIPNL
CDKN2A interacting protein N-terminal like
chr2_+_233734994 0.16 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr17_+_74261413 0.16 ENST00000587913.1
UBALD2
UBA-like domain containing 2
chr2_+_191513587 0.16 ENST00000416973.1
ENST00000426601.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr7_+_72848092 0.15 ENST00000344575.3
FZD9
frizzled family receptor 9
chr22_-_24989014 0.15 ENST00000318753.8
FAM211B
family with sequence similarity 211, member B
chrX_-_47004437 0.15 ENST00000276062.8
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chrX_+_129305623 0.15 ENST00000257017.4
RAB33A
RAB33A, member RAS oncogene family
chr20_-_32274179 0.15 ENST00000343380.5
E2F1
E2F transcription factor 1
chr14_+_102027688 0.15 ENST00000510508.4
ENST00000359323.3
DIO3
deiodinase, iodothyronine, type III
chr12_+_56137064 0.14 ENST00000257868.5
ENST00000546799.1
GDF11
growth differentiation factor 11
chr16_-_67694129 0.14 ENST00000602320.1
ACD
adrenocortical dysplasia homolog (mouse)
chr15_-_53082178 0.14 ENST00000305901.5
ONECUT1
one cut homeobox 1
chr1_+_113217309 0.14 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr6_+_30848829 0.14 ENST00000508317.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr18_+_43914159 0.14 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165
ring finger protein 165
chr2_+_11052054 0.14 ENST00000295082.1
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr12_+_122064673 0.13 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr12_+_122064398 0.13 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr1_+_20915409 0.13 ENST00000375071.3
CDA
cytidine deaminase
chr16_-_88772761 0.13 ENST00000567844.1
ENST00000312838.4
RNF166
ring finger protein 166
chr6_+_44095263 0.13 ENST00000532634.1
TMEM63B
transmembrane protein 63B
chr3_-_178789220 0.12 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr11_-_6341844 0.12 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr6_-_90121938 0.12 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr19_-_55791058 0.12 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr3_-_32022733 0.12 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr4_+_89300158 0.12 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr9_-_34126730 0.12 ENST00000361264.4
DCAF12
DDB1 and CUL4 associated factor 12
chr16_-_67693846 0.12 ENST00000602850.1
ACD
adrenocortical dysplasia homolog (mouse)
chr19_+_13228917 0.12 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr16_-_29910365 0.12 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr16_+_771663 0.12 ENST00000568916.1
FAM173A
family with sequence similarity 173, member A
chr1_-_27693349 0.12 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr9_-_140095186 0.12 ENST00000409012.4
TPRN
taperin
chr13_+_88325498 0.12 ENST00000400028.3
SLITRK5
SLIT and NTRK-like family, member 5
chr19_+_39989580 0.11 ENST00000596614.1
ENST00000205143.4
DLL3
delta-like 3 (Drosophila)
chr22_+_45072925 0.11 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr1_+_32538492 0.11 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr11_-_66725837 0.11 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC
pyruvate carboxylase
chr2_-_239148599 0.11 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6
hes family bHLH transcription factor 6
chr16_-_31106211 0.11 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
RP11-196G11.1
VKORC1
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr9_-_111929560 0.11 ENST00000561981.2
FRRS1L
ferric-chelate reductase 1-like
chr16_-_70285797 0.11 ENST00000435634.1
EXOSC6
exosome component 6
chr6_+_30848557 0.11 ENST00000460944.2
ENST00000324771.8
DDR1
discoidin domain receptor tyrosine kinase 1
chr14_-_37051798 0.11 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr22_-_42342692 0.11 ENST00000404067.1
ENST00000402338.1
CENPM
centromere protein M
chr17_+_74261277 0.11 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr16_-_31106048 0.11 ENST00000300851.6
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr4_-_2758015 0.11 ENST00000510267.1
ENST00000503235.1
ENST00000315423.7
TNIP2
TNFAIP3 interacting protein 2
chr15_+_80215477 0.11 ENST00000542003.1
C15ORF37
C15orf37 protein; Uncharacterized protein
chr5_-_178772424 0.11 ENST00000251582.7
ENST00000274609.5
ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr16_+_88772866 0.11 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
CTU2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr16_+_3014269 0.10 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
KREMEN2
kringle containing transmembrane protein 2
chr19_+_41107249 0.10 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr7_+_150065879 0.10 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
REPIN1
ZNF775
replication initiator 1
zinc finger protein 775
chr19_-_47104118 0.10 ENST00000593888.1
ENST00000602017.1
AC011551.3
PPP5D1
Uncharacterized protein
PPP5 tetratricopeptide repeat domain containing 1
chr3_-_87040259 0.10 ENST00000383698.3
VGLL3
vestigial like 3 (Drosophila)
chr17_-_31204124 0.10 ENST00000579584.1
ENST00000318217.5
ENST00000583621.1
MYO1D
myosin ID
chr8_+_128747661 0.10 ENST00000259523.6
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr20_+_30193083 0.10 ENST00000376112.3
ENST00000376105.3
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr19_+_36132631 0.10 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr22_-_20850070 0.10 ENST00000440659.2
ENST00000458248.1
ENST00000443285.1
ENST00000444967.1
ENST00000451553.1
ENST00000431430.1
KLHL22
kelch-like family member 22
chr5_+_52776228 0.10 ENST00000256759.3
FST
follistatin
chr2_-_230135937 0.10 ENST00000392054.3
ENST00000409462.1
ENST00000392055.3
PID1
phosphotyrosine interaction domain containing 1
chr20_-_62680984 0.10 ENST00000340356.7
SOX18
SRY (sex determining region Y)-box 18
chr19_-_45737469 0.10 ENST00000413988.1
EXOC3L2
exocyst complex component 3-like 2
chr12_+_123459747 0.10 ENST00000228922.7
ENST00000537966.1
OGFOD2
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr5_+_139027877 0.09 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr11_+_65383227 0.09 ENST00000355703.3
PCNXL3
pecanex-like 3 (Drosophila)
chr15_+_40650408 0.09 ENST00000267889.3
DISP2
dispatched homolog 2 (Drosophila)
chr19_-_17366257 0.09 ENST00000594059.1
AC010646.3
Uncharacterized protein
chr22_+_38054721 0.09 ENST00000215904.6
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr7_-_74867509 0.09 ENST00000426327.3
GATSL2
GATS protein-like 2
chr1_+_113217345 0.09 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr10_+_94833642 0.09 ENST00000224356.4
ENST00000394139.1
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr9_+_140119618 0.09 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chr11_-_64014379 0.09 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr5_+_52776449 0.09 ENST00000396947.3
FST
follistatin
chr10_+_12391685 0.09 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr11_+_60635035 0.09 ENST00000278853.5
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr17_+_74723031 0.09 ENST00000586200.1
METTL23
methyltransferase like 23
chr3_-_5229982 0.09 ENST00000600805.1
AC026202.1
Uncharacterized protein
chr7_+_766320 0.09 ENST00000297440.6
ENST00000313147.5
HEATR2
HEAT repeat containing 2
chr6_-_31681839 0.09 ENST00000409239.1
ENST00000461287.1
LY6G6E
XXbac-BPG32J3.20
lymphocyte antigen 6 complex, locus G6E (pseudogene)
Uncharacterized protein
chr11_+_827553 0.09 ENST00000528542.2
ENST00000450448.1
EFCAB4A
EF-hand calcium binding domain 4A
chr3_-_64253655 0.09 ENST00000498162.1
PRICKLE2
prickle homolog 2 (Drosophila)
chr11_-_6341724 0.09 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr14_-_54423529 0.08 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr2_-_73340146 0.08 ENST00000258098.6
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr19_-_47734448 0.08 ENST00000439096.2
BBC3
BCL2 binding component 3
chr22_+_45072958 0.08 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr4_-_80994471 0.08 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr14_-_24911868 0.08 ENST00000554698.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr19_+_12949251 0.08 ENST00000251472.4
MAST1
microtubule associated serine/threonine kinase 1
chr12_-_67197760 0.08 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr3_-_99833333 0.08 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L
filamin A interacting protein 1-like
chr12_-_52887034 0.08 ENST00000330722.6
KRT6A
keratin 6A
chr18_+_3448455 0.08 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr19_-_3061397 0.08 ENST00000586839.1
AES
amino-terminal enhancer of split
chr6_+_43395272 0.08 ENST00000372530.4
ABCC10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr17_+_74722912 0.08 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
METTL23
methyltransferase like 23
chr20_+_35234137 0.08 ENST00000344795.3
ENST00000373852.5
C20orf24
chromosome 20 open reading frame 24
chr8_-_38008783 0.08 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chrX_-_153285251 0.08 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr12_-_54813229 0.08 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr11_-_65374430 0.08 ENST00000532507.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr8_+_128747757 0.08 ENST00000517291.1
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr3_-_172428842 0.07 ENST00000424772.1
NCEH1
neutral cholesterol ester hydrolase 1
chr16_+_75033210 0.07 ENST00000566250.1
ENST00000567962.1
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr22_-_50964849 0.07 ENST00000543927.1
ENST00000423348.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr20_-_35274548 0.07 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr11_-_1606513 0.07 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr1_-_11107280 0.07 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr12_-_54779511 0.07 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr2_+_198570081 0.07 ENST00000282276.6
MARS2
methionyl-tRNA synthetase 2, mitochondrial
chr19_-_40730820 0.07 ENST00000513948.1
CNTD2
cyclin N-terminal domain containing 2
chr22_+_45098067 0.07 ENST00000336985.6
ENST00000403696.1
ENST00000457960.1
ENST00000361473.5
PRR5
PRR5-ARHGAP8
proline rich 5 (renal)
PRR5-ARHGAP8 readthrough
chr19_-_55628927 0.07 ENST00000263433.3
ENST00000376393.2
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr12_+_53491220 0.07 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr20_+_49575342 0.07 ENST00000244051.1
MOCS3
molybdenum cofactor synthesis 3
chr7_+_766850 0.07 ENST00000437419.1
ENST00000440747.1
HEATR2
HEAT repeat containing 2
chr11_+_62554860 0.07 ENST00000533861.1
ENST00000333449.4
TMEM179B
transmembrane protein 179B
chr15_+_79603404 0.07 ENST00000299705.5
TMED3
transmembrane emp24 protein transport domain containing 3
chr2_-_72375167 0.07 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr4_-_54930790 0.07 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr17_-_73761222 0.07 ENST00000437911.1
ENST00000225614.2
GALK1
galactokinase 1
chr1_-_38273840 0.07 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr15_+_74833518 0.07 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr19_+_17858509 0.07 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr4_+_89299885 0.07 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr5_-_133747589 0.07 ENST00000458198.2
CDKN2AIPNL
CDKN2A interacting protein N-terminal like
chr4_-_80994210 0.06 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr1_+_955448 0.06 ENST00000379370.2
AGRN
agrin
chr14_-_64971893 0.06 ENST00000555220.1
ZBTB25
zinc finger and BTB domain containing 25
chr20_+_49348081 0.06 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr11_+_394196 0.06 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr16_-_69373396 0.06 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr1_-_32687923 0.06 ENST00000309777.6
ENST00000344461.3
ENST00000373593.1
ENST00000545122.1
TMEM234
transmembrane protein 234
chr12_+_113796347 0.06 ENST00000545182.2
ENST00000280800.3
PLBD2
phospholipase B domain containing 2
chr1_-_3713042 0.06 ENST00000378251.1
LRRC47
leucine rich repeat containing 47
chr11_-_61124776 0.06 ENST00000542361.1
CYB561A3
cytochrome b561 family, member A3
chr19_+_12780512 0.06 ENST00000242796.4
WDR83
WD repeat domain 83
chr2_-_73511407 0.06 ENST00000520530.2
FBXO41
F-box protein 41
chrX_-_153285395 0.06 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr19_-_17445613 0.06 ENST00000159087.4
ANO8
anoctamin 8
chr11_-_14913765 0.06 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr6_+_159290917 0.06 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr7_-_100171270 0.06 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr20_-_43438912 0.06 ENST00000541604.2
ENST00000372851.3
RIMS4
regulating synaptic membrane exocytosis 4
chr1_-_6662919 0.06 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr17_+_65040678 0.06 ENST00000226021.3
CACNG1
calcium channel, voltage-dependent, gamma subunit 1
chr9_+_100615536 0.06 ENST00000375123.3
FOXE1
forkhead box E1 (thyroid transcription factor 2)
chr9_-_131940526 0.06 ENST00000372491.2
IER5L
immediate early response 5-like
chr22_-_50964558 0.06 ENST00000535425.1
ENST00000439934.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr11_-_31531121 0.06 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr17_+_28256874 0.06 ENST00000541045.1
ENST00000536908.2
EFCAB5
EF-hand calcium binding domain 5
chr16_+_5121814 0.06 ENST00000262374.5
ENST00000586840.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr1_+_32538520 0.06 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B
transmembrane protein 39B
chr5_-_148758839 0.06 ENST00000261796.3
IL17B
interleukin 17B
chr19_-_46272462 0.06 ENST00000317578.6
SIX5
SIX homeobox 5
chr17_+_81037473 0.06 ENST00000320095.7
METRNL
meteorin, glial cell differentiation regulator-like
chr17_+_74864476 0.06 ENST00000301618.4
ENST00000569840.2
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr4_-_102268628 0.06 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_193155729 0.06 ENST00000367434.4
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr19_+_46001697 0.06 ENST00000451287.2
ENST00000324688.4
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 0.4 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.2 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.2 GO:0014060 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) epinephrine secretion(GO:0048242)
0.1 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.0 GO:0072185 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0060264 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0 0.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.1 GO:0017143 insecticide metabolic process(GO:0017143) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.2 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.1 GO:0061150 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.0 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0072034 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) renal vesicle induction(GO:0072034) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.3 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.3 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0098519 phosphoserine phosphatase activity(GO:0004647) nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation