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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for NFIA

Z-value: 1.83

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Transcription factors associated with NFIA

Gene Symbol Gene ID Gene Info
NFIA
ENSG00000162599.11 nuclear factor I A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIAhg19_v2_chr1_+_61548225_61548299-0.891.1e-01Click!

Activity profile of NFIA motif

Sorted Z-values of NFIA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_95975672 1.06 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr4_-_157892055 0.86 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr14_+_77582905 0.86 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr5_-_34043310 0.80 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr1_+_112016414 0.79 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr14_-_98444386 0.76 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chrX_-_71497148 0.74 ENST00000316084.6
RPS4X
ribosomal protein S4, X-linked
chr1_-_114429997 0.66 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr12_-_13248598 0.66 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr9_+_130911770 0.65 ENST00000372998.1
LCN2
lipocalin 2
chr7_+_79764104 0.58 ENST00000351004.3
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr7_-_151330218 0.57 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr10_+_135340859 0.57 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr18_+_61144160 0.57 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr7_-_17598506 0.56 ENST00000451792.1
AC017060.1
AC017060.1
chr11_-_122931881 0.55 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chr17_+_67957878 0.53 ENST00000420427.1
AC004562.1
AC004562.1
chr8_+_66619277 0.53 ENST00000521247.2
ENST00000527155.1
MTFR1
mitochondrial fission regulator 1
chr11_+_111749650 0.53 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr5_-_156362666 0.52 ENST00000406964.1
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr12_+_48225126 0.52 ENST00000550909.1
ENST00000550720.1
ENST00000548564.1
RP5-1057I20.2
RP5-1057I20.2
chr11_+_77774897 0.52 ENST00000281030.2
THRSP
thyroid hormone responsive
chr19_+_42254885 0.52 ENST00000595740.1
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr2_+_3705785 0.51 ENST00000252505.3
ALLC
allantoicase
chr3_-_105588231 0.50 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr2_+_33701684 0.49 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr13_-_100624012 0.48 ENST00000267294.4
ZIC5
Zic family member 5
chrX_-_119693745 0.46 ENST00000371323.2
CUL4B
cullin 4B
chr3_-_52488048 0.46 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr6_-_10115007 0.46 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr5_+_74807581 0.45 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chrX_-_69479654 0.45 ENST00000374519.2
P2RY4
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr8_+_124194875 0.45 ENST00000522648.1
ENST00000276699.6
FAM83A
family with sequence similarity 83, member A
chr21_+_44394742 0.45 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chr5_-_55008136 0.45 ENST00000503891.1
ENST00000507109.1
SLC38A9
solute carrier family 38, member 9
chr5_-_43313574 0.44 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr12_+_110718428 0.44 ENST00000552636.1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr2_+_136289030 0.43 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1
R3H domain containing 1
chr12_+_100897130 0.43 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr5_-_180018540 0.43 ENST00000292641.3
SCGB3A1
secretoglobin, family 3A, member 1
chr5_-_168006324 0.43 ENST00000522176.1
PANK3
pantothenate kinase 3
chrX_-_71497077 0.41 ENST00000373626.3
RPS4X
ribosomal protein S4, X-linked
chr13_-_36705425 0.41 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1
doublecortin-like kinase 1
chr8_-_71519889 0.40 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr12_+_56435637 0.40 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr1_-_204119009 0.39 ENST00000444817.1
ETNK2
ethanolamine kinase 2
chr7_-_27135591 0.38 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr4_+_146402346 0.37 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr2_-_180871780 0.37 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr11_-_93271058 0.37 ENST00000527149.1
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr18_+_20494078 0.37 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr5_+_112074029 0.37 ENST00000512211.2
APC
adenomatous polyposis coli
chr6_+_13925098 0.37 ENST00000488300.1
ENST00000544682.1
ENST00000420478.2
RNF182
ring finger protein 182
chr14_-_38036271 0.37 ENST00000556024.1
RP11-356O9.2
RP11-356O9.2
chr7_+_129932974 0.36 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4
carboxypeptidase A4
chr16_-_21442874 0.36 ENST00000534903.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr14_-_69350920 0.36 ENST00000553290.1
ACTN1
actinin, alpha 1
chr12_+_93965609 0.36 ENST00000549887.1
ENST00000551556.1
SOCS2
suppressor of cytokine signaling 2
chr12_+_110562135 0.36 ENST00000361948.4
ENST00000552912.1
ENST00000242591.5
ENST00000546374.1
IFT81
intraflagellar transport 81 homolog (Chlamydomonas)
chr9_+_123906331 0.35 ENST00000431571.1
CNTRL
centriolin
chr3_+_52350335 0.35 ENST00000420323.2
DNAH1
dynein, axonemal, heavy chain 1
chr1_+_170501270 0.35 ENST00000367763.3
ENST00000367762.1
GORAB
golgin, RAB6-interacting
chr2_-_69180083 0.35 ENST00000328895.4
GKN2
gastrokine 2
chr5_+_112073544 0.34 ENST00000257430.4
ENST00000508376.2
APC
adenomatous polyposis coli
chr4_-_111558135 0.34 ENST00000394598.2
ENST00000394595.3
PITX2
paired-like homeodomain 2
chr17_-_37764128 0.34 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr14_-_64194745 0.34 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr3_+_32737027 0.34 ENST00000454516.2
CNOT10
CCR4-NOT transcription complex, subunit 10
chr6_-_86353510 0.34 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr5_-_43313269 0.34 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr8_+_97597148 0.34 ENST00000521590.1
SDC2
syndecan 2
chr8_+_104384616 0.34 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr6_-_2971494 0.34 ENST00000380539.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr17_+_65375082 0.34 ENST00000584471.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr8_+_32579271 0.33 ENST00000518084.1
NRG1
neuregulin 1
chr13_+_78109804 0.33 ENST00000535157.1
SCEL
sciellin
chr17_+_1733276 0.33 ENST00000254719.5
RPA1
replication protein A1, 70kDa
chr17_-_40169161 0.32 ENST00000589586.2
ENST00000426588.3
ENST00000589576.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr11_-_113644491 0.32 ENST00000200135.3
ZW10
zw10 kinetochore protein
chr17_+_54671047 0.32 ENST00000332822.4
NOG
noggin
chr13_+_78109884 0.32 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr11_+_33037652 0.31 ENST00000311388.3
DEPDC7
DEP domain containing 7
chr14_-_50319758 0.31 ENST00000298310.5
NEMF
nuclear export mediator factor
chr17_-_42188598 0.31 ENST00000591714.1
HDAC5
histone deacetylase 5
chr22_-_23922410 0.31 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr1_+_153746683 0.31 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr5_-_55008101 0.31 ENST00000506624.1
ENST00000513275.1
ENST00000513993.1
SLC38A9
solute carrier family 38, member 9
chr2_-_61244550 0.30 ENST00000421319.1
PUS10
pseudouridylate synthase 10
chr15_+_41549105 0.30 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr2_-_136288740 0.30 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr17_+_1733251 0.30 ENST00000570451.1
RPA1
replication protein A1, 70kDa
chr12_-_21910775 0.30 ENST00000539782.1
LDHB
lactate dehydrogenase B
chr18_+_61143994 0.30 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr17_-_39459103 0.30 ENST00000391353.1
KRTAP29-1
keratin associated protein 29-1
chr1_-_154164534 0.30 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr8_+_124194752 0.30 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr8_+_102064237 0.29 ENST00000514926.1
RP11-302J23.1
RP11-302J23.1
chr2_+_33701707 0.29 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_+_159570722 0.29 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr16_-_15474904 0.29 ENST00000534094.1
NPIPA5
nuclear pore complex interacting protein family, member A5
chr3_-_131736593 0.29 ENST00000514999.1
CPNE4
copine IV
chr2_-_211036051 0.29 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L
KAT8 regulatory NSL complex subunit 1-like
chr15_+_36994210 0.29 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr11_+_34654011 0.29 ENST00000531794.1
EHF
ets homologous factor
chr3_-_93747425 0.29 ENST00000315099.2
STX19
syntaxin 19
chr22_+_38864041 0.29 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr4_+_76439095 0.28 ENST00000506261.1
THAP6
THAP domain containing 6
chr1_+_68150744 0.28 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr3_+_152017360 0.28 ENST00000485910.1
ENST00000463374.1
MBNL1
muscleblind-like splicing regulator 1
chr3_+_142342240 0.28 ENST00000497199.1
PLS1
plastin 1
chr3_+_150264458 0.28 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr2_+_62132781 0.28 ENST00000311832.5
COMMD1
copper metabolism (Murr1) domain containing 1
chr5_+_89770696 0.28 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chrX_-_19817869 0.27 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr5_+_122847908 0.27 ENST00000511130.2
ENST00000512718.3
CSNK1G3
casein kinase 1, gamma 3
chr17_-_15168624 0.27 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr12_-_53207842 0.27 ENST00000458244.2
KRT4
keratin 4
chr12_-_95510743 0.27 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr4_-_113437328 0.27 ENST00000313341.3
NEUROG2
neurogenin 2
chr13_+_23755054 0.27 ENST00000218867.3
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr9_+_137967366 0.27 ENST00000252854.4
OLFM1
olfactomedin 1
chr18_-_12884259 0.27 ENST00000353319.4
ENST00000327283.3
PTPN2
protein tyrosine phosphatase, non-receptor type 2
chr1_-_235098935 0.27 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr3_-_52002194 0.27 ENST00000466412.1
PCBP4
poly(rC) binding protein 4
chr9_+_17134980 0.27 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr17_-_47786375 0.27 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr9_-_129885010 0.27 ENST00000373425.3
ANGPTL2
angiopoietin-like 2
chr1_+_15986364 0.27 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr6_+_43968306 0.26 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr5_-_142783694 0.26 ENST00000394466.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_54684327 0.26 ENST00000389980.3
SPTBN1
spectrin, beta, non-erythrocytic 1
chr6_+_126221034 0.26 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chrX_+_135252050 0.25 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr19_-_40724246 0.25 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr3_-_25824872 0.25 ENST00000308710.5
NGLY1
N-glycanase 1
chr10_-_13390021 0.25 ENST00000537130.1
SEPHS1
selenophosphate synthetase 1
chr2_-_114300213 0.25 ENST00000446595.1
ENST00000416105.1
ENST00000450636.1
ENST00000416758.1
RP11-395L14.4
RP11-395L14.4
chr13_-_46425865 0.25 ENST00000400405.2
SIAH3
siah E3 ubiquitin protein ligase family member 3
chr14_+_55494323 0.25 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr11_+_62556596 0.25 ENST00000526546.1
TMEM179B
transmembrane protein 179B
chr8_-_16859690 0.24 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr11_-_122930121 0.24 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr10_-_14050522 0.24 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr9_+_17135016 0.24 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr11_+_34643600 0.24 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr11_-_64013288 0.24 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_-_236046872 0.24 ENST00000536965.1
LYST
lysosomal trafficking regulator
chr3_+_69788576 0.24 ENST00000352241.4
ENST00000448226.2
MITF
microphthalmia-associated transcription factor
chr11_-_13461790 0.24 ENST00000530907.1
BTBD10
BTB (POZ) domain containing 10
chr4_+_146402997 0.24 ENST00000512019.1
SMAD1
SMAD family member 1
chr5_-_74807418 0.24 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr10_-_5227096 0.24 ENST00000488756.1
ENST00000334314.3
AKR1CL1
aldo-keto reductase family 1, member C-like 1
chr20_-_14318248 0.23 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chrX_-_135849484 0.23 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr17_+_79031415 0.23 ENST00000572073.1
ENST00000573677.1
BAIAP2
BAI1-associated protein 2
chr10_-_61122220 0.23 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C
family with sequence similarity 13, member C
chr5_+_122847781 0.23 ENST00000395412.1
ENST00000395411.1
ENST00000345990.4
CSNK1G3
casein kinase 1, gamma 3
chr7_+_17338239 0.23 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr19_-_1812193 0.23 ENST00000525591.1
ATP8B3
ATPase, aminophospholipid transporter, class I, type 8B, member 3
chr17_-_67224812 0.23 ENST00000423818.2
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr1_-_114430169 0.23 ENST00000393316.3
BCL2L15
BCL2-like 15
chrX_+_122993657 0.23 ENST00000434753.3
ENST00000430625.1
XIAP
X-linked inhibitor of apoptosis
chr3_+_109128837 0.23 ENST00000497996.1
RP11-702L6.4
RP11-702L6.4
chr8_+_121457642 0.23 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr4_+_146402925 0.23 ENST00000302085.4
SMAD1
SMAD family member 1
chr6_+_13925318 0.23 ENST00000423553.2
ENST00000537388.1
RNF182
ring finger protein 182
chr12_-_82752565 0.22 ENST00000256151.7
CCDC59
coiled-coil domain containing 59
chr2_-_219925189 0.22 ENST00000295731.6
IHH
indian hedgehog
chrX_-_106146547 0.22 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr12_-_99038732 0.22 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP
IKBKB interacting protein
chr14_+_70234642 0.22 ENST00000555349.1
ENST00000554021.1
SRSF5
serine/arginine-rich splicing factor 5
chr14_+_55493920 0.22 ENST00000395472.2
ENST00000555846.1
SOCS4
suppressor of cytokine signaling 4
chr22_+_24129138 0.22 ENST00000417137.1
ENST00000344921.6
ENST00000263121.7
ENST00000407422.3
ENST00000407082.3
SMARCB1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
chr10_-_27149851 0.22 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
ABI1
abl-interactor 1
chr19_-_12997995 0.22 ENST00000264834.4
KLF1
Kruppel-like factor 1 (erythroid)
chr16_+_22518495 0.22 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr11_+_193065 0.22 ENST00000342878.2
SCGB1C1
secretoglobin, family 1C, member 1
chr6_+_42989344 0.22 ENST00000244496.5
RRP36
ribosomal RNA processing 36 homolog (S. cerevisiae)
chr6_-_32784687 0.22 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr17_+_27369918 0.22 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr5_-_43515231 0.22 ENST00000306862.2
C5orf34
chromosome 5 open reading frame 34
chr2_+_192543694 0.21 ENST00000435931.1
NABP1
nucleic acid binding protein 1
chr1_-_160253998 0.21 ENST00000392220.2
PEX19
peroxisomal biogenesis factor 19
chr7_+_107332334 0.21 ENST00000541474.1
ENST00000544569.1
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr3_-_37216055 0.21 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr2_+_43864387 0.21 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr12_-_82752159 0.21 ENST00000552377.1
CCDC59
coiled-coil domain containing 59
chr1_+_66797687 0.21 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_-_61348292 0.21 ENST00000539008.1
ENST00000540677.1
ENST00000542836.1
ENST00000542670.1
ENST00000535826.1
ENST00000545053.1
SYT7
synaptotagmin VII
chr5_-_55777586 0.21 ENST00000506836.1
CTC-236F12.4
Uncharacterized protein
chr16_+_82090028 0.21 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr11_-_125550726 0.21 ENST00000315608.3
ENST00000530048.1
ACRV1
acrosomal vesicle protein 1
chrX_-_85302531 0.21 ENST00000537751.1
ENST00000358786.4
ENST00000357749.2
CHM
choroideremia (Rab escort protein 1)
chr11_-_85430204 0.21 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr15_+_38544476 0.20 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr3_+_186501979 0.20 ENST00000498746.1
EIF4A2
eukaryotic translation initiation factor 4A2
chr3_+_152017924 0.20 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1
chr11_-_85430088 0.20 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr1_+_46379254 0.20 ENST00000372008.2
MAST2
microtubule associated serine/threonine kinase 2
chr7_+_35756092 0.20 ENST00000458087.3
AC018647.3
AC018647.3

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043605 cellular amide catabolic process(GO:0043605)
0.2 0.8 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.2 0.2 GO:0061056 sclerotome development(GO:0061056)
0.1 0.7 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.4 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.5 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 1.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.4 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.5 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 0.6 GO:0010193 response to ozone(GO:0010193)
0.1 0.4 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.3 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.3 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.3 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.7 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.2 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.2 GO:0001757 somite specification(GO:0001757)
0.1 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.1 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.6 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.3 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.3 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle cell proliferation(GO:0014858) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.4 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 0.2 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.1 0.2 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.4 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.1 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.0 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.2 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.3 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.8 GO:0009642 response to light intensity(GO:0009642) response to vitamin E(GO:0033197)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.3 GO:1902510 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.5 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.4 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 1.1 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.3 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0014740 regulation of muscle hyperplasia(GO:0014738) negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.4 GO:0060294 inner dynein arm assembly(GO:0036159) cilium movement involved in cell motility(GO:0060294)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.2 GO:0097324 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0030578 PML body organization(GO:0030578)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.0 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 0.1 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.2 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.3 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.6 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.5 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.4 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 2.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.6 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.8 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.3 GO:1990423 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.8 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.0 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.7 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.4 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.1 0.4 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.4 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.5 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells