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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for NFIA
Z-value: 1.83
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Transcription factors associated with NFIA
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NFIA | hg19_v2_chr1_+_61548225_61548299 | -0.89 | 1.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_95975672 Show fit | 1.06 |
ENST00000440116.2
ENST00000456933.1 |
RP11-286B14.1 |
|
| chr4_-_157892055 Show fit | 0.86 |
ENST00000422544.2
|
platelet derived growth factor C |
|
| chr14_+_77582905 Show fit | 0.86 |
ENST00000557408.1
|
transmembrane protein 63C |
|
| chr5_-_34043310 Show fit | 0.80 |
ENST00000231338.7
|
C1q and tumor necrosis factor related protein 3 |
|
| chr1_+_112016414 Show fit | 0.79 |
ENST00000343534.5
ENST00000369718.3 |
chromosome 1 open reading frame 162 |
|
| chr14_-_98444386 Show fit | 0.76 |
ENST00000556462.1
ENST00000556138.1 |
chromosome 14 open reading frame 64 |
|
| chrX_-_71497148 Show fit | 0.74 |
ENST00000316084.6
|
ribosomal protein S4, X-linked |
|
| chr1_-_114429997 Show fit | 0.66 |
ENST00000471267.1
ENST00000393320.3 |
BCL2-like 15 |
|
| chr12_-_13248598 Show fit | 0.66 |
ENST00000337630.6
ENST00000545699.1 |
germ cell associated 1 |
|
| chr9_+_130911770 Show fit | 0.65 |
ENST00000372998.1
|
lipocalin 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of NFIA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.1 | 1.2 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.0 | 1.1 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.0 | 1.1 | GO:0006293 | nucleotide-excision repair, preincision complex stabilization(GO:0006293) |
| 0.1 | 1.0 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.0 | 1.0 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 0.8 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 0.0 | 0.8 | GO:0009642 | response to light intensity(GO:0009642) response to vitamin E(GO:0033197) |
| 0.0 | 0.8 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.1 | 0.7 | GO:0015688 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.9 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 0.8 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.1 | 0.8 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.0 | 0.7 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.7 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 0.6 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.6 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 1.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 1.1 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.9 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.0 | 0.9 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
| 0.1 | 0.8 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.8 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.0 | 0.8 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.0 | 0.7 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.7 | GO:0070411 | I-SMAD binding(GO:0070411) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 1.2 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.2 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 1.1 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 1.0 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 0.9 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.8 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.8 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.8 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 0.7 | PID ALK2 PATHWAY | ALK2 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 1.0 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 1.0 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.9 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.8 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 0.7 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 0.6 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.0 | 0.6 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.6 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |