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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for NANOG
Z-value: 1.02
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Transcription factors associated with NANOG
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NANOG | hg19_v2_chr12_+_7941989_7942014 | -0.14 | 8.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_72509751 Show fit | 0.53 |
ENST00000515556.1
ENST00000513379.1 ENST00000427584.2 |
RP11-60A8.1 |
|
| chr2_+_149402009 Show fit | 0.41 |
ENST00000457184.1
|
enhancer of polycomb homolog 2 (Drosophila) |
|
| chr6_-_31632962 Show fit | 0.39 |
ENST00000456540.1
ENST00000445768.1 |
G patch domain and ankyrin repeats 1 |
|
| chr19_+_37825614 Show fit | 0.38 |
ENST00000591259.1
ENST00000590582.1 |
HKR1, GLI-Kruppel zinc finger family member |
|
| chr8_+_142264664 Show fit | 0.34 |
ENST00000518520.1
|
Uncharacterized protein |
|
| chr14_-_98444386 Show fit | 0.34 |
ENST00000556462.1
ENST00000556138.1 |
chromosome 14 open reading frame 64 |
|
| chr8_-_42751728 Show fit | 0.33 |
ENST00000319104.3
ENST00000531440.1 |
ring finger protein 170 |
|
| chr3_-_71803917 Show fit | 0.32 |
ENST00000421769.2
|
eukaryotic translation initiation factor 4E family member 3 |
|
| chr19_+_39926791 Show fit | 0.31 |
ENST00000594990.1
|
suppressor of Ty 5 homolog (S. cerevisiae) |
|
| chr16_-_30997533 Show fit | 0.27 |
ENST00000602217.1
|
Uncharacterized protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of NANOG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0046168 | glycerol-3-phosphate catabolic process(GO:0046168) |
| 0.1 | 0.3 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.0 | 0.3 | GO:0032785 | negative regulation of DNA-templated transcription, elongation(GO:0032785) |
| 0.0 | 0.3 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.1 | 0.2 | GO:1904247 | positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 0.1 | 0.2 | GO:0033341 | regulation of collagen binding(GO:0033341) |
| 0.0 | 0.2 | GO:0035669 | TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669) |
| 0.0 | 0.2 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.0 | 0.2 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.0 | 0.1 | GO:0090222 | centrosome-templated microtubule nucleation(GO:0090222) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.1 | 0.3 | GO:0032044 | DSIF complex(GO:0032044) |
| 0.0 | 0.3 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.3 | GO:0005845 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.0 | 0.3 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 0.2 | GO:0005940 | septin ring(GO:0005940) septin collar(GO:0032173) |
| 0.0 | 0.2 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.2 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
| 0.1 | 0.2 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.0 | 0.2 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.1 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.0 | 0.1 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.0 | 0.1 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
| 0.0 | 0.1 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.0 | 0.1 | GO:0019863 | IgE binding(GO:0019863) |
| 0.0 | 0.0 | GO:0071566 | UFM1 activating enzyme activity(GO:0071566) |
| 0.0 | 0.0 | GO:0004915 | interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME PEPTIDE HORMONE BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |