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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 0.47

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Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4

Gene Symbol Gene ID Gene Info
MIXL1
ENSG00000185155.7 Mix paired-like homeobox
GSX1
ENSG00000169840.4 GS homeobox 1
BSX
ENSG00000188909.4 brain specific homeobox
MEOX2
ENSG00000106511.5 mesenchyme homeobox 2
LHX4
ENSG00000121454.4 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX4hg19_v2_chr1_+_180199393_180199426-0.425.8e-01Click!
MIXL1hg19_v2_chr1_+_226411319_226411366-0.039.7e-01Click!

Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_1922789 0.50 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr12_-_91546926 0.47 ENST00000550758.1
DCN
decorin
chr5_+_66300464 0.43 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr16_+_53412368 0.39 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr2_+_179318295 0.39 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr17_-_46690839 0.39 ENST00000498634.2
HOXB8
homeobox B8
chr14_-_51027838 0.29 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr17_-_38956205 0.28 ENST00000306658.7
KRT28
keratin 28
chr1_+_62439037 0.26 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr7_+_77428066 0.26 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr7_+_77428149 0.26 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr5_+_136070614 0.25 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr18_-_33709268 0.24 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr15_+_63188009 0.24 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr12_+_64798826 0.23 ENST00000540203.1
XPOT
exportin, tRNA
chr14_-_57960456 0.21 ENST00000534126.1
ENST00000422976.2
C14orf105
chromosome 14 open reading frame 105
chr16_+_53133070 0.21 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr14_+_20187174 0.21 ENST00000557414.1
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr1_+_174844645 0.20 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr7_-_28220354 0.20 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr3_-_69129501 0.19 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr7_-_27169801 0.19 ENST00000511914.1
HOXA4
homeobox A4
chr5_+_115177178 0.18 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr8_+_92114873 0.18 ENST00000343709.3
ENST00000448384.2
LRRC69
leucine rich repeat containing 69
chr13_-_36788718 0.18 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr7_-_33102338 0.18 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr3_+_159557637 0.17 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr17_-_39623681 0.17 ENST00000225899.3
KRT32
keratin 32
chr6_-_138833630 0.17 ENST00000533765.1
NHSL1
NHS-like 1
chr7_-_33102399 0.17 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr14_+_65016620 0.16 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr19_-_7698599 0.16 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr6_-_138866823 0.16 ENST00000342260.5
NHSL1
NHS-like 1
chr12_-_74686314 0.15 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr6_+_153552455 0.15 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr11_-_117747434 0.15 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr10_-_115904361 0.15 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr2_-_136678123 0.15 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr7_+_6655225 0.15 ENST00000457543.3
ZNF853
zinc finger protein 853
chr8_-_90996459 0.15 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr3_-_151034734 0.15 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr10_-_104866395 0.15 ENST00000458345.1
NT5C2
5'-nucleotidase, cytosolic II
chr2_+_149402989 0.14 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chrX_+_107334895 0.14 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr15_-_31393910 0.14 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr8_-_112248400 0.14 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chrX_+_13671225 0.14 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr12_+_16500599 0.14 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr15_+_80351910 0.14 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr4_+_169013666 0.14 ENST00000359299.3
ANXA10
annexin A10
chr2_-_114461655 0.14 ENST00000424612.1
AC017074.2
AC017074.2
chr1_-_242612779 0.14 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr5_-_142780280 0.14 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_+_39944025 0.13 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr13_-_44735393 0.13 ENST00000400419.1
SMIM2
small integral membrane protein 2
chr10_+_13141585 0.13 ENST00000378764.2
OPTN
optineurin
chr12_+_104337515 0.13 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr6_+_126221034 0.13 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr7_-_151217166 0.13 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr18_-_56985873 0.13 ENST00000299721.3
CPLX4
complexin 4
chr9_-_75488984 0.13 ENST00000423171.1
ENST00000449235.1
ENST00000453787.1
RP11-151D14.1
RP11-151D14.1
chr6_+_76330355 0.13 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr19_-_58485895 0.12 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr12_+_20963647 0.12 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_-_117748138 0.12 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr2_-_55647057 0.12 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr4_+_146402346 0.12 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr14_+_101295638 0.12 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr10_-_105110831 0.12 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr2_+_109204743 0.11 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_-_123542224 0.11 ENST00000264497.3
IL21
interleukin 21
chr17_-_57229155 0.11 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr13_-_41593425 0.11 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr12_-_112123524 0.11 ENST00000327551.6
BRAP
BRCA1 associated protein
chrX_-_73512177 0.11 ENST00000603672.1
ENST00000418855.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chrX_-_106243451 0.11 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr1_-_48937838 0.11 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr2_-_74618907 0.11 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr5_+_89770664 0.11 ENST00000503973.1
ENST00000399107.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr18_+_3247779 0.11 ENST00000578611.1
ENST00000583449.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_-_151762943 0.11 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH
tudor and KH domain containing
chr12_+_28410128 0.11 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chrX_-_106243294 0.11 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr11_-_108093329 0.11 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr1_+_111415757 0.10 ENST00000429072.2
ENST00000271324.5
CD53
CD53 molecule
chrX_-_19817869 0.10 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr1_-_242612726 0.10 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr13_+_78315348 0.10 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr3_-_145940126 0.10 ENST00000498625.1
PLSCR4
phospholipid scramblase 4
chr13_+_78315466 0.10 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr1_-_168464875 0.10 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr3_+_182983126 0.10 ENST00000481531.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr2_+_109237717 0.10 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_-_110937351 0.10 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr8_+_26150628 0.10 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr14_-_92247032 0.10 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB
catsper channel auxiliary subunit beta
chr6_-_116833500 0.10 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr2_+_7118755 0.10 ENST00000433456.1
RNF144A
ring finger protein 144A
chr19_-_52307357 0.10 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr8_-_27469383 0.10 ENST00000519742.1
CLU
clusterin
chr1_+_229440129 0.09 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr2_+_38152462 0.09 ENST00000354545.2
RMDN2
regulator of microtubule dynamics 2
chr1_+_28527070 0.09 ENST00000596102.1
AL353354.2
AL353354.2
chr14_-_64194745 0.09 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chrX_+_149867681 0.09 ENST00000438018.1
ENST00000436701.1
MTMR1
myotubularin related protein 1
chrX_+_123097014 0.09 ENST00000394478.1
STAG2
stromal antigen 2
chr12_-_89746173 0.09 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr17_-_38928414 0.09 ENST00000335552.4
KRT26
keratin 26
chr6_-_32784687 0.09 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr9_-_5304432 0.09 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr10_-_92681033 0.09 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr1_-_95391315 0.09 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr5_-_137475071 0.09 ENST00000265191.2
NME5
NME/NM23 family member 5
chr10_-_105110890 0.09 ENST00000369847.3
PCGF6
polycomb group ring finger 6
chr5_-_89770582 0.09 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr3_-_141747950 0.09 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_+_135502501 0.09 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr15_+_86087267 0.09 ENST00000558166.1
AKAP13
A kinase (PRKA) anchor protein 13
chr3_+_148447887 0.09 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr2_+_182850551 0.09 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr16_-_53737722 0.09 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr12_+_16500571 0.09 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr6_-_52859046 0.09 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr10_+_90660832 0.09 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr2_-_17981462 0.08 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr14_+_62164340 0.08 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr16_-_66864806 0.08 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr9_-_16728161 0.08 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr3_+_141106458 0.08 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr16_-_3350614 0.08 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr5_+_89770696 0.08 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr3_-_191000172 0.08 ENST00000427544.2
UTS2B
urotensin 2B
chr5_+_81601166 0.08 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr7_-_14029283 0.08 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr1_+_38478378 0.08 ENST00000373014.4
UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr4_-_76944621 0.08 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr2_+_182850743 0.08 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_-_72070206 0.08 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr8_-_102216925 0.08 ENST00000517844.1
ZNF706
zinc finger protein 706
chr5_-_102455801 0.08 ENST00000508629.1
ENST00000399004.2
GIN1
gypsy retrotransposon integrase 1
chrX_-_46187069 0.08 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr12_+_41136144 0.08 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr4_-_36245561 0.08 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_80351977 0.08 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chrX_+_21874105 0.08 ENST00000429584.2
YY2
YY2 transcription factor
chr2_+_200472779 0.08 ENST00000427045.1
ENST00000419243.1
AC093590.1
AC093590.1
chrX_-_71458802 0.08 ENST00000373657.1
ENST00000334463.3
ERCC6L
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr3_-_108248169 0.08 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr18_+_32556892 0.08 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr10_-_25304889 0.08 ENST00000483339.2
ENKUR
enkurin, TRPC channel interacting protein
chrX_+_95939638 0.07 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr6_+_149887377 0.07 ENST00000367419.5
GINM1
glycoprotein integral membrane 1
chr6_+_131571535 0.07 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr4_-_170897045 0.07 ENST00000508313.1
RP11-205M3.3
RP11-205M3.3
chr18_+_71815743 0.07 ENST00000169551.6
ENST00000580087.1
TIMM21
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr7_-_92747269 0.07 ENST00000446617.1
ENST00000379958.2
SAMD9
sterile alpha motif domain containing 9
chr17_-_19619917 0.07 ENST00000325411.5
ENST00000350657.5
ENST00000433844.2
SLC47A2
solute carrier family 47 (multidrug and toxin extrusion), member 2
chr7_+_1272522 0.07 ENST00000316333.8
UNCX
UNC homeobox
chr8_+_101170563 0.07 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chr17_+_45000483 0.07 ENST00000576910.2
ENST00000439730.2
ENST00000393456.2
ENST00000415811.2
ENST00000575949.1
ENST00000225567.4
ENST00000572403.1
ENST00000570879.1
GOSR2
golgi SNAP receptor complex member 2
chr9_-_21305312 0.07 ENST00000259555.4
IFNA5
interferon, alpha 5
chr19_+_52800410 0.07 ENST00000595962.1
ENST00000598016.1
ENST00000334564.7
ENST00000490272.1
ZNF480
zinc finger protein 480
chr11_+_107461804 0.07 ENST00000531234.1
ELMOD1
ELMO/CED-12 domain containing 1
chr12_+_16500037 0.07 ENST00000536371.1
ENST00000010404.2
MGST1
microsomal glutathione S-transferase 1
chr19_+_56270380 0.07 ENST00000434937.2
RFPL4A
ret finger protein-like 4A
chr1_+_112016414 0.07 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr18_+_57567180 0.07 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr19_+_13049413 0.07 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chrX_+_134654540 0.07 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr1_-_54411255 0.07 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr12_-_95510743 0.07 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr13_+_78315528 0.07 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr14_-_98444386 0.07 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr2_+_109204909 0.07 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr10_+_17686193 0.07 ENST00000377500.1
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr8_+_92114060 0.07 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr3_+_130569429 0.07 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr11_+_101918153 0.07 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr7_-_112635675 0.07 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr10_+_13141441 0.07 ENST00000263036.5
OPTN
optineurin
chr3_-_12587055 0.07 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr16_+_14280564 0.07 ENST00000572567.1
MKL2
MKL/myocardin-like 2
chr7_+_138145076 0.07 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr12_-_118628315 0.07 ENST00000540561.1
TAOK3
TAO kinase 3
chr14_-_88200641 0.07 ENST00000556168.1
RP11-1152H15.1
RP11-1152H15.1
chrX_+_70798261 0.07 ENST00000373696.3
ACRC
acidic repeat containing
chrM_+_9207 0.07 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr14_+_61654271 0.06 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr6_+_3259148 0.06 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr5_-_87516448 0.06 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr2_+_29001711 0.06 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr2_-_44550441 0.06 ENST00000420756.1
ENST00000444696.1
PREPL
prolyl endopeptidase-like
chr12_+_122688090 0.06 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr3_+_111717511 0.06 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr12_-_54653313 0.06 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr8_+_38831683 0.06 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr6_+_28092338 0.06 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr4_+_183065793 0.06 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr4_+_76649797 0.06 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr17_-_38938786 0.06 ENST00000301656.3
KRT27
keratin 27

Network of associatons between targets according to the STRING database.

First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.0 GO:0016540 protein autoprocessing(GO:0016540) positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.1 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.4 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.0 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.0 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.0 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.1 GO:1903056 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.0 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.0 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.0 GO:0006173 dADP biosynthetic process(GO:0006173)
0.0 0.0 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0010819 regulation of T cell chemotaxis(GO:0010819)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.0 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.0 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.0 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.0 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.0 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.0 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.0 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR