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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for MEF2D_MEF2A

Z-value: 0.85

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Transcription factors associated with MEF2D_MEF2A

Gene Symbol Gene ID Gene Info
MEF2D
ENSG00000116604.13 myocyte enhancer factor 2D
MEF2A
ENSG00000068305.13 myocyte enhancer factor 2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Dhg19_v2_chr1_-_156470515_156470542-0.998.3e-03Click!
MEF2Ahg19_v2_chr15_+_100106670_1001066970.982.2e-02Click!

Activity profile of MEF2D_MEF2A motif

Sorted Z-values of MEF2D_MEF2A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_68165657 0.49 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr21_+_35107346 0.37 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr15_+_100106244 0.34 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr14_+_56046990 0.34 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
KTN1
kinectin 1 (kinesin receptor)
chr8_+_107282368 0.32 ENST00000521369.2
RP11-395G23.3
RP11-395G23.3
chr12_-_49393092 0.31 ENST00000421952.2
DDN
dendrin
chr12_+_54384370 0.30 ENST00000504315.1
HOXC6
homeobox C6
chr7_+_143013198 0.30 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr1_-_226187013 0.29 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr16_+_31225337 0.29 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr4_+_37892682 0.28 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr17_-_48785216 0.27 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr4_+_124571409 0.26 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr17_-_42188598 0.26 ENST00000591714.1
HDAC5
histone deacetylase 5
chr22_+_32340481 0.26 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr4_-_143767428 0.25 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr3_+_141106643 0.24 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr14_-_62217779 0.24 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr15_+_100106126 0.24 ENST00000558812.1
ENST00000338042.6
MEF2A
myocyte enhancer factor 2A
chr5_+_138609782 0.24 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
MATR3
matrin 3
chr1_+_25757376 0.24 ENST00000399766.3
ENST00000399763.3
ENST00000374343.4
TMEM57
transmembrane protein 57
chr3_-_108248169 0.24 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr1_-_223853425 0.23 ENST00000366873.2
ENST00000419193.2
CAPN8
calpain 8
chr12_-_111358372 0.22 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr14_+_56046914 0.22 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr5_-_137475071 0.20 ENST00000265191.2
NME5
NME/NM23 family member 5
chr17_+_7184986 0.20 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr10_-_45474237 0.19 ENST00000448778.1
ENST00000298295.3
C10orf10
chromosome 10 open reading frame 10
chr1_-_100643765 0.19 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39
leucine rich repeat containing 39
chr1_+_90098606 0.19 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr14_+_39735411 0.19 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr17_+_7758374 0.18 ENST00000301599.6
ENST00000574668.1
TMEM88
transmembrane protein 88
chr1_-_223853348 0.18 ENST00000366872.5
CAPN8
calpain 8
chr22_+_32340447 0.18 ENST00000248975.5
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr14_-_103989033 0.18 ENST00000553878.1
ENST00000557530.1
CKB
creatine kinase, brain
chrX_-_55208866 0.18 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr15_+_80364901 0.18 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr18_+_3252265 0.18 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr19_-_51220176 0.18 ENST00000359082.3
ENST00000293441.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr14_-_21493649 0.18 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2
NDRG family member 2
chr5_-_150521192 0.17 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chr4_-_185303418 0.17 ENST00000610223.1
ENST00000608785.1
RP11-290F5.1
RP11-290F5.1
chr17_-_41132088 0.16 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr3_+_159570722 0.16 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr3_+_193853927 0.16 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr17_-_34524157 0.16 ENST00000378354.4
ENST00000394484.1
CCL3L3
chemokine (C-C motif) ligand 3-like 3
chr5_+_66300464 0.16 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr19_+_45973120 0.16 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr12_+_119616447 0.16 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr1_-_154164534 0.15 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr1_+_212782012 0.15 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr1_-_59249732 0.15 ENST00000371222.2
JUN
jun proto-oncogene
chr1_+_203097407 0.15 ENST00000367235.1
ADORA1
adenosine A1 receptor
chr9_+_129677123 0.15 ENST00000373436.1
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr14_-_21493884 0.15 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2
NDRG family member 2
chr2_+_103378472 0.15 ENST00000412401.2
TMEM182
transmembrane protein 182
chr1_-_206945830 0.15 ENST00000423557.1
IL10
interleukin 10
chr3_+_36421971 0.15 ENST00000457375.2
ENST00000434649.1
STAC
SH3 and cysteine rich domain
chr9_+_127054254 0.15 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr2_-_148779106 0.15 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr11_+_65266507 0.14 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr8_+_107282389 0.14 ENST00000577661.1
ENST00000445937.1
RP11-395G23.3
OXR1
RP11-395G23.3
oxidation resistance 1
chr1_+_26348259 0.14 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr3_-_39234074 0.14 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1
xin actin-binding repeat containing 1
chr12_-_131200810 0.14 ENST00000536002.1
ENST00000544034.1
RIMBP2
RP11-662M24.2
RIMS binding protein 2
RP11-662M24.2
chr8_-_62602327 0.14 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr11_-_47400062 0.14 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr16_+_30075595 0.14 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr7_+_18535321 0.14 ENST00000413380.1
ENST00000430454.1
HDAC9
histone deacetylase 9
chr15_+_100106155 0.14 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
MEF2A
myocyte enhancer factor 2A
chr12_-_68845165 0.13 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2
RP11-81H14.2
chr14_+_76776957 0.13 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr1_+_145525015 0.13 ENST00000539363.1
ENST00000538811.1
ITGA10
integrin, alpha 10
chr9_-_130639997 0.13 ENST00000373176.1
AK1
adenylate kinase 1
chr2_-_165424973 0.13 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr1_+_151129135 0.13 ENST00000602841.1
SCNM1
sodium channel modifier 1
chr11_+_3666335 0.13 ENST00000250693.1
ART1
ADP-ribosyltransferase 1
chr12_-_57644952 0.13 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3
SH3 and cysteine rich domain 3
chr13_-_50367057 0.13 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr1_+_160051319 0.13 ENST00000368088.3
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr9_-_16728161 0.13 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr18_-_35145728 0.12 ENST00000361795.5
ENST00000603232.1
CELF4
CUGBP, Elav-like family member 4
chr10_+_23728198 0.12 ENST00000376495.3
OTUD1
OTU domain containing 1
chr3_-_4927447 0.12 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr1_+_24018269 0.12 ENST00000374550.3
RPL11
ribosomal protein L11
chr16_+_30075783 0.12 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chrX_-_142722897 0.12 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr17_+_27369918 0.12 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr2_-_148778323 0.12 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr10_+_86184676 0.12 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr3_+_121311966 0.12 ENST00000338040.4
FBXO40
F-box protein 40
chr12_+_110562135 0.12 ENST00000361948.4
ENST00000552912.1
ENST00000242591.5
ENST00000546374.1
IFT81
intraflagellar transport 81 homolog (Chlamydomonas)
chr6_+_123038689 0.12 ENST00000354275.2
ENST00000368446.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr16_+_15737124 0.12 ENST00000396355.1
ENST00000396353.2
NDE1
nudE neurodevelopment protein 1
chr8_-_17533838 0.12 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr15_+_59730348 0.12 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr12_-_16760195 0.12 ENST00000546281.1
ENST00000537757.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_141106458 0.12 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr1_-_117753540 0.11 ENST00000328189.3
ENST00000369458.3
VTCN1
V-set domain containing T cell activation inhibitor 1
chr10_+_50507232 0.11 ENST00000374144.3
C10orf71
chromosome 10 open reading frame 71
chr9_+_5450503 0.11 ENST00000381573.4
ENST00000381577.3
CD274
CD274 molecule
chr8_+_1993173 0.11 ENST00000523438.1
MYOM2
myomesin 2
chr22_-_40929812 0.11 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr5_-_111091948 0.11 ENST00000447165.2
NREP
neuronal regeneration related protein
chr20_+_61147651 0.11 ENST00000370527.3
ENST00000370524.2
C20orf166
chromosome 20 open reading frame 166
chr3_-_27498235 0.11 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr1_+_68150744 0.11 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr8_+_76452097 0.11 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr3_-_192445289 0.11 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr8_-_73793975 0.11 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr7_+_152456829 0.11 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr12_-_45269430 0.11 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr1_-_150693318 0.11 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chr12_-_49581152 0.11 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr1_+_156096336 0.10 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr5_+_96077888 0.10 ENST00000509259.1
ENST00000503828.1
CAST
calpastatin
chrX_+_18725758 0.10 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr13_-_103346854 0.10 ENST00000267273.6
METTL21C
methyltransferase like 21C
chr4_-_83280767 0.10 ENST00000514671.1
HNRNPD
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr21_+_17909594 0.10 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr10_+_88428206 0.10 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3
LIM domain binding 3
chr2_-_148778258 0.10 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4
origin recognition complex, subunit 4
chr11_+_77774897 0.10 ENST00000281030.2
THRSP
thyroid hormone responsive
chr7_-_35013217 0.10 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr7_-_30739661 0.10 ENST00000445981.1
ENST00000348438.4
CRHR2
corticotropin releasing hormone receptor 2
chr7_-_151217166 0.10 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr17_-_49021974 0.10 ENST00000501718.2
RP11-700H6.1
RP11-700H6.1
chr3_+_127634312 0.10 ENST00000407609.3
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr2_-_10588630 0.10 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr3_+_127634069 0.10 ENST00000405109.1
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chrX_+_70521584 0.09 ENST00000373829.3
ENST00000538820.1
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr3_-_145878954 0.09 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr11_-_62457371 0.09 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr6_+_132129151 0.09 ENST00000360971.2
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr9_+_100263912 0.09 ENST00000259365.4
TMOD1
tropomodulin 1
chr14_+_56078695 0.09 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr4_+_95373037 0.09 ENST00000359265.4
ENST00000437932.1
ENST00000380180.3
ENST00000318007.5
ENST00000450793.1
ENST00000538141.1
ENST00000317968.4
ENST00000512274.1
ENST00000503974.1
ENST00000504489.1
ENST00000542407.1
PDLIM5
PDZ and LIM domain 5
chr1_-_150693305 0.09 ENST00000368987.1
HORMAD1
HORMA domain containing 1
chr15_+_40531243 0.09 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr2_-_151344172 0.09 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr8_-_74659693 0.09 ENST00000518767.1
STAU2
staufen double-stranded RNA binding protein 2
chr15_-_99057551 0.09 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr8_-_70745575 0.09 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr11_+_7598239 0.09 ENST00000525597.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_+_69928256 0.09 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr1_+_145524891 0.08 ENST00000369304.3
ITGA10
integrin, alpha 10
chr22_-_31328881 0.08 ENST00000445980.1
MORC2
MORC family CW-type zinc finger 2
chr5_-_159546396 0.08 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A
PWWP domain containing 2A
chr2_-_106054952 0.08 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr15_+_78830023 0.08 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr10_+_50507181 0.08 ENST00000323868.4
C10orf71
chromosome 10 open reading frame 71
chr2_-_31637560 0.08 ENST00000379416.3
XDH
xanthine dehydrogenase
chr18_-_64271316 0.08 ENST00000540086.1
ENST00000580157.1
CDH19
cadherin 19, type 2
chr13_+_76334498 0.08 ENST00000534657.1
LMO7
LIM domain 7
chr10_+_14880157 0.08 ENST00000378372.3
HSPA14
heat shock 70kDa protein 14
chr13_+_76210448 0.08 ENST00000377499.5
LMO7
LIM domain 7
chr8_+_74903580 0.08 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr7_-_37488547 0.08 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr13_+_76334567 0.08 ENST00000321797.8
LMO7
LIM domain 7
chr12_-_48111295 0.08 ENST00000542202.1
ENDOU
endonuclease, polyU-specific
chr1_-_159825137 0.08 ENST00000368102.1
C1orf204
chromosome 1 open reading frame 204
chr1_+_150254936 0.08 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr1_-_201390846 0.08 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
TNNI1
troponin I type 1 (skeletal, slow)
chr8_+_27631903 0.08 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr18_+_9708162 0.08 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chrX_+_119384607 0.08 ENST00000326624.2
ENST00000557385.1
ZBTB33
zinc finger and BTB domain containing 33
chr13_+_76334795 0.08 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr14_-_89021077 0.08 ENST00000556564.1
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr3_-_176914238 0.08 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr4_-_76823681 0.08 ENST00000286719.7
PPEF2
protein phosphatase, EF-hand calcium binding domain 2
chr4_+_160025300 0.08 ENST00000505478.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr15_+_40531621 0.07 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr15_-_83474806 0.07 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr2_+_113403434 0.07 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr1_+_150245099 0.07 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr22_-_51017084 0.07 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr10_+_88428370 0.07 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chr16_-_15736953 0.07 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
KIAA0430
chr1_+_84630645 0.07 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_-_151217001 0.07 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr3_-_148939835 0.07 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr9_+_70971815 0.07 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr7_+_152456904 0.07 ENST00000537264.1
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr22_+_41487711 0.07 ENST00000263253.7
EP300
E1A binding protein p300
chr2_-_157198860 0.07 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr14_-_102704783 0.07 ENST00000522534.1
MOK
MOK protein kinase
chr2_+_44502597 0.07 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr11_-_47399942 0.07 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr22_-_51016846 0.07 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr20_-_14318248 0.07 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr3_-_52486841 0.07 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr4_+_160203650 0.07 ENST00000514565.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr8_+_67039131 0.07 ENST00000315962.4
ENST00000353317.5
TRIM55
tripartite motif containing 55
chr17_-_48277552 0.07 ENST00000507689.1
COL1A1
collagen, type I, alpha 1
chr12_+_44229846 0.07 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr10_+_71561649 0.07 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr14_+_100150622 0.07 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr1_+_160085501 0.07 ENST00000361216.3
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr3_+_69812877 0.07 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr3_+_113616317 0.06 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2D_MEF2A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0051098 regulation of protein binding(GO:0043393) regulation of binding(GO:0051098)
0.1 0.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.3 GO:0044026 DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.1 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.1 0.2 GO:0060164 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) regulation of timing of neuron differentiation(GO:0060164) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.1 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:1903216 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.0 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0071288 nitric oxide transport(GO:0030185) carbon dioxide transmembrane transport(GO:0035378) cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0035529 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.0 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.0 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins