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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for MECOM

Z-value: 0.55

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Transcription factors associated with MECOM

Gene Symbol Gene ID Gene Info
MECOM
ENSG00000085276.13 MDS1 and EVI1 complex locus

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MECOMhg19_v2_chr3_-_168865522_168865536-0.928.3e-02Click!

Activity profile of MECOM motif

Sorted Z-values of MECOM motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_52520828 0.31 ENST00000610127.1
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr12_+_113860160 0.19 ENST00000553248.1
ENST00000345635.4
ENST00000547802.1
SDSL
serine dehydratase-like
chr12_-_85430024 0.18 ENST00000547836.1
ENST00000532498.2
TSPAN19
tetraspanin 19
chr4_+_155484103 0.18 ENST00000302068.4
FGB
fibrinogen beta chain
chr4_+_130014836 0.17 ENST00000502887.1
C4orf33
chromosome 4 open reading frame 33
chr8_+_72740402 0.17 ENST00000521467.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr19_-_36391434 0.16 ENST00000396901.1
ENST00000585925.1
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr2_-_27435390 0.16 ENST00000428518.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr2_-_27435634 0.15 ENST00000430186.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr17_+_70036164 0.15 ENST00000602013.1
AC007461.1
Uncharacterized protein
chr4_+_26323764 0.15 ENST00000514730.1
ENST00000507574.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_1763721 0.14 ENST00000437146.1
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr12_+_113860042 0.14 ENST00000403593.4
SDSL
serine dehydratase-like
chr9_+_33240157 0.14 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chr4_+_155484155 0.14 ENST00000509493.1
FGB
fibrinogen beta chain
chr8_-_133637624 0.13 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr4_+_26324474 0.13 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chrX_+_155227246 0.12 ENST00000244174.5
ENST00000424344.3
IL9R
interleukin 9 receptor
chr15_+_41057818 0.12 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chrX_-_149999722 0.12 ENST00000418547.1
CD99L2
CD99 molecule-like 2
chr8_+_97773202 0.12 ENST00000519484.1
CPQ
carboxypeptidase Q
chr12_+_21207503 0.11 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr5_-_130868688 0.11 ENST00000504575.1
ENST00000513227.1
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chrX_+_86772787 0.11 ENST00000373114.4
KLHL4
kelch-like family member 4
chr19_+_47538560 0.11 ENST00000439365.2
ENST00000594670.1
NPAS1
neuronal PAS domain protein 1
chr19_-_54106751 0.11 ENST00000600193.1
CTB-167G5.5
Uncharacterized protein
chr9_+_6645887 0.10 ENST00000413145.1
RP11-390F4.6
RP11-390F4.6
chr14_-_39639523 0.10 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
TRAPPC6B
trafficking protein particle complex 6B
chr3_-_184971817 0.10 ENST00000440662.1
ENST00000456310.1
EHHADH
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr3_-_119379427 0.10 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2
popeye domain containing 2
chr8_+_105602961 0.10 ENST00000521923.1
RP11-127H5.1
Uncharacterized protein
chr16_+_71879861 0.10 ENST00000427980.2
ENST00000568581.1
ATXN1L
IST1
ataxin 1-like
increased sodium tolerance 1 homolog (yeast)
chr1_-_85156417 0.10 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr19_-_20844368 0.09 ENST00000595094.1
ENST00000601440.1
ENST00000291750.6
CTC-513N18.7
ZNF626
CTC-513N18.7
zinc finger protein 626
chr19_+_23257988 0.09 ENST00000594318.1
ENST00000600223.1
ENST00000593635.1
CTD-2291D10.4
ZNF730
CTD-2291D10.4
zinc finger protein 730
chr11_+_57559005 0.09 ENST00000534647.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr4_+_96012585 0.09 ENST00000502683.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr7_+_73275483 0.09 ENST00000320531.2
WBSCR28
Williams-Beuren syndrome chromosome region 28
chrY_+_15418467 0.08 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr7_+_44040488 0.08 ENST00000258704.3
SPDYE1
speedy/RINGO cell cycle regulator family member E1
chr3_-_130746462 0.08 ENST00000505545.1
ASTE1
asteroid homolog 1 (Drosophila)
chr15_-_55562451 0.08 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr4_+_164415785 0.08 ENST00000513272.1
ENST00000513134.1
TMA16
translation machinery associated 16 homolog (S. cerevisiae)
chr3_+_99986036 0.08 ENST00000471098.1
TBC1D23
TBC1 domain family, member 23
chr2_+_172544182 0.08 ENST00000409197.1
ENST00000456808.1
ENST00000409317.1
ENST00000409773.1
ENST00000411953.1
ENST00000409453.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr5_-_96209315 0.08 ENST00000504056.1
CTD-2260A17.2
Uncharacterized protein
chr12_+_85430110 0.08 ENST00000393212.3
ENST00000393217.2
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr8_-_6420759 0.08 ENST00000523120.1
ANGPT2
angiopoietin 2
chr12_+_32638897 0.08 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_-_76039000 0.08 ENST00000275560.3
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr8_+_134203303 0.07 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WISP1
WNT1 inducible signaling pathway protein 1
chr12_+_113344755 0.07 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr7_-_8302298 0.07 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chr16_+_14280742 0.07 ENST00000341243.5
MKL2
MKL/myocardin-like 2
chr3_-_184971853 0.07 ENST00000231887.3
EHHADH
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr10_-_18940501 0.07 ENST00000377304.4
NSUN6
NOP2/Sun domain family, member 6
chr5_+_74807886 0.07 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr5_+_64920543 0.07 ENST00000399438.3
ENST00000510585.2
TRAPPC13
CTC-534A2.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr10_-_21186144 0.07 ENST00000377119.1
NEBL
nebulette
chr5_+_64920826 0.07 ENST00000438419.2
ENST00000231526.4
ENST00000505553.1
ENST00000545191.1
TRAPPC13
trafficking protein particle complex 13
chr1_+_110158726 0.07 ENST00000531734.1
AMPD2
adenosine monophosphate deaminase 2
chr17_-_56494882 0.07 ENST00000584437.1
RNF43
ring finger protein 43
chr17_-_56494908 0.07 ENST00000577716.1
RNF43
ring finger protein 43
chr3_-_45883558 0.07 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chr2_+_190541153 0.06 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr7_-_33140498 0.06 ENST00000448915.1
RP9
retinitis pigmentosa 9 (autosomal dominant)
chr15_+_42566384 0.06 ENST00000440615.2
ENST00000318010.8
GANC
glucosidase, alpha; neutral C
chr7_-_29152509 0.06 ENST00000448959.1
CPVL
carboxypeptidase, vitellogenic-like
chr4_+_117220016 0.06 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)
chr15_-_102285007 0.06 ENST00000560292.2
RP11-89K11.1
Uncharacterized protein
chr14_-_82089405 0.06 ENST00000554211.1
RP11-799P8.1
RP11-799P8.1
chr2_+_172544294 0.06 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr15_-_40401062 0.06 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr10_+_57358750 0.06 ENST00000512524.2
MTRNR2L5
MT-RNR2-like 5
chr14_-_76447336 0.06 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr2_+_172543919 0.05 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr5_-_171404730 0.05 ENST00000518752.1
FBXW11
F-box and WD repeat domain containing 11
chr21_+_17214724 0.05 ENST00000449491.1
USP25
ubiquitin specific peptidase 25
chr1_-_157069590 0.05 ENST00000454449.2
ETV3L
ets variant 3-like
chr2_+_108145913 0.05 ENST00000443205.1
AC096669.3
AC096669.3
chrX_-_85302531 0.05 ENST00000537751.1
ENST00000358786.4
ENST00000357749.2
CHM
choroideremia (Rab escort protein 1)
chr13_-_46626847 0.05 ENST00000242848.4
ENST00000282007.3
ZC3H13
zinc finger CCCH-type containing 13
chr5_-_64920115 0.05 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr9_+_134378289 0.05 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
POMT1
protein-O-mannosyltransferase 1
chr14_-_38028689 0.05 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr5_-_158526693 0.05 ENST00000380654.4
EBF1
early B-cell factor 1
chr7_-_8302164 0.05 ENST00000447326.1
ENST00000406470.2
ICA1
islet cell autoantigen 1, 69kDa
chr15_+_40532723 0.05 ENST00000558878.1
ENST00000558183.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr8_+_86999516 0.05 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr12_-_76879852 0.05 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr6_+_49431073 0.05 ENST00000335783.3
CENPQ
centromere protein Q
chr16_-_90096309 0.04 ENST00000408886.2
C16orf3
chromosome 16 open reading frame 3
chr8_-_49834299 0.04 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr12_-_57522813 0.04 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr15_-_83837983 0.04 ENST00000562702.1
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr2_+_172543967 0.04 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr3_+_184534994 0.04 ENST00000441141.1
ENST00000445089.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr11_+_17316870 0.04 ENST00000458064.2
NUCB2
nucleobindin 2
chrX_+_66764375 0.04 ENST00000374690.3
AR
androgen receptor
chr5_+_92919043 0.04 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr17_-_56494713 0.04 ENST00000407977.2
RNF43
ring finger protein 43
chr4_-_143226979 0.04 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr3_+_99357319 0.04 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1
collagen, type VIII, alpha 1
chr4_+_96012614 0.04 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr6_-_53530474 0.04 ENST00000370905.3
KLHL31
kelch-like family member 31
chr15_-_38852251 0.04 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr15_-_48470544 0.04 ENST00000267836.6
MYEF2
myelin expression factor 2
chr9_-_112970436 0.04 ENST00000400613.4
C9orf152
chromosome 9 open reading frame 152
chr2_+_27805971 0.04 ENST00000413371.2
ZNF512
zinc finger protein 512
chrX_-_19905577 0.03 ENST00000379697.3
SH3KBP1
SH3-domain kinase binding protein 1
chr3_-_145968923 0.03 ENST00000493382.1
ENST00000354952.2
ENST00000383083.2
PLSCR4
phospholipid scramblase 4
chr5_+_140739537 0.03 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr2_+_190540711 0.03 ENST00000520309.1
ANKAR
ankyrin and armadillo repeat containing
chr15_+_59665194 0.03 ENST00000560394.1
FAM81A
family with sequence similarity 81, member A
chr11_-_94965667 0.03 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr6_-_75912508 0.03 ENST00000416123.2
COL12A1
collagen, type XII, alpha 1
chr12_-_12715266 0.03 ENST00000228862.2
DUSP16
dual specificity phosphatase 16
chr12_-_53297432 0.03 ENST00000546900.1
KRT8
keratin 8
chr15_+_52155001 0.03 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr15_+_100348193 0.03 ENST00000558188.1
CTD-2054N24.2
Uncharacterized protein
chr14_-_25479811 0.03 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr20_+_36012051 0.03 ENST00000373567.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr10_-_48806939 0.03 ENST00000374233.3
ENST00000507417.1
ENST00000512321.1
ENST00000395660.2
ENST00000374235.2
ENST00000395661.3
PTPN20B
protein tyrosine phosphatase, non-receptor type 20B
chr12_+_53836339 0.03 ENST00000549135.1
PRR13
proline rich 13
chr7_-_8302207 0.03 ENST00000407906.1
ICA1
islet cell autoantigen 1, 69kDa
chr5_+_159895275 0.03 ENST00000517927.1
MIR146A
microRNA 146a
chr4_-_100065440 0.03 ENST00000508393.1
ENST00000265512.7
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr12_-_15865844 0.03 ENST00000543612.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr2_+_172544011 0.03 ENST00000508530.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr2_-_231989808 0.03 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chrX_+_129473916 0.03 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr4_-_143227088 0.03 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr7_+_44240520 0.03 ENST00000496112.1
ENST00000223369.2
YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr1_+_171939240 0.03 ENST00000523513.1
DNM3
dynamin 3
chr14_-_24551195 0.03 ENST00000560550.1
NRL
neural retina leucine zipper
chr11_-_33891362 0.03 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr16_+_14280564 0.03 ENST00000572567.1
MKL2
MKL/myocardin-like 2
chr1_+_47901689 0.03 ENST00000334793.5
FOXD2
forkhead box D2
chr19_-_14316980 0.03 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr11_-_8964580 0.03 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr3_+_121311966 0.02 ENST00000338040.4
FBXO40
F-box protein 40
chr12_+_21168630 0.02 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr6_-_32784687 0.02 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr5_-_158526756 0.02 ENST00000313708.6
ENST00000517373.1
EBF1
early B-cell factor 1
chr8_-_27115903 0.02 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
STMN4
stathmin-like 4
chr1_+_172422026 0.02 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr4_-_52883786 0.02 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr13_+_111855399 0.02 ENST00000426768.2
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr16_-_73093597 0.02 ENST00000397992.5
ZFHX3
zinc finger homeobox 3
chr3_-_119379719 0.02 ENST00000493094.1
POPDC2
popeye domain containing 2
chr14_-_24551137 0.02 ENST00000396995.1
NRL
neural retina leucine zipper
chr20_-_45985172 0.02 ENST00000536340.1
ZMYND8
zinc finger, MYND-type containing 8
chr17_+_53344945 0.02 ENST00000575345.1
HLF
hepatic leukemia factor
chr11_+_47587129 0.02 ENST00000326656.8
ENST00000326674.9
PTPMT1
protein tyrosine phosphatase, mitochondrial 1
chr14_+_24584056 0.02 ENST00000561001.1
DCAF11
DDB1 and CUL4 associated factor 11
chr4_-_122148620 0.02 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chr10_-_29923893 0.02 ENST00000355867.4
SVIL
supervillin
chrX_-_10588595 0.02 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr11_+_60145997 0.02 ENST00000530614.1
ENST00000530027.1
ENST00000530234.2
ENST00000528215.1
ENST00000531787.1
MS4A7
MS4A14
membrane-spanning 4-domains, subfamily A, member 7
membrane-spanning 4-domains, subfamily A, member 14
chr4_-_76944621 0.02 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr4_+_189321881 0.02 ENST00000512839.1
ENST00000513313.1
LINC01060
long intergenic non-protein coding RNA 1060
chr16_-_50402690 0.02 ENST00000394689.2
BRD7
bromodomain containing 7
chr7_-_112726393 0.02 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85
G protein-coupled receptor 85
chr17_-_37309480 0.02 ENST00000539608.1
PLXDC1
plexin domain containing 1
chr2_+_204571198 0.02 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
CD28
CD28 molecule
chr16_-_71758602 0.02 ENST00000568954.1
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr12_+_53835539 0.02 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
PRR13
proline rich 13
chr20_-_30310336 0.02 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr12_+_57522692 0.02 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr12_+_57522439 0.02 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr3_-_145968857 0.02 ENST00000433593.2
ENST00000476202.1
ENST00000460885.1
PLSCR4
phospholipid scramblase 4
chrX_+_102883620 0.02 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr20_-_45985414 0.02 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
ZMYND8
zinc finger, MYND-type containing 8
chr13_+_76334567 0.02 ENST00000321797.8
LMO7
LIM domain 7
chr8_+_134203273 0.02 ENST00000250160.6
WISP1
WNT1 inducible signaling pathway protein 1
chr3_+_57875711 0.02 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr1_+_109102652 0.02 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chrX_-_106243294 0.02 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr10_-_14596140 0.02 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr5_+_167956121 0.02 ENST00000338333.4
FBLL1
fibrillarin-like 1
chr10_+_116524547 0.02 ENST00000436932.1
RP11-106M7.1
RP11-106M7.1
chr12_-_95945246 0.02 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr17_-_32484313 0.02 ENST00000359872.6
ASIC2
acid-sensing (proton-gated) ion channel 2
chr2_+_55746722 0.02 ENST00000339012.3
CCDC104
coiled-coil domain containing 104
chr20_-_45984401 0.01 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr12_-_371994 0.01 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chr13_+_76334498 0.01 ENST00000534657.1
LMO7
LIM domain 7
chr4_-_76598544 0.01 ENST00000515457.1
ENST00000357854.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr14_-_24584138 0.01 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr1_+_82266053 0.01 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr17_-_40346477 0.01 ENST00000593209.1
ENST00000587427.1
ENST00000588352.1
ENST00000414034.3
ENST00000590249.1
GHDC
GH3 domain containing
chr2_+_97779233 0.01 ENST00000461153.2
ENST00000420699.2
ANKRD36
ankyrin repeat domain 36
chr7_-_30008849 0.01 ENST00000409497.1
SCRN1
secernin 1
chr5_+_20616500 0.01 ENST00000512688.1
RP11-774D14.1
RP11-774D14.1
chr1_+_160160346 0.01 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr14_+_24584508 0.01 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11
DDB1 and CUL4 associated factor 11
chr2_+_189839046 0.01 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr12_+_124457746 0.01 ENST00000392404.3
ENST00000538932.2
ENST00000337815.4
ENST00000540762.2
ZNF664
FAM101A
zinc finger protein 664
family with sequence similarity 101, member A
chr8_-_23282797 0.01 ENST00000524144.1
LOXL2
lysyl oxidase-like 2
chr7_-_6006768 0.01 ENST00000441023.2
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)

Network of associatons between targets according to the STRING database.

First level regulatory network of MECOM

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.0 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.0 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway