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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for MAZ_ZNF281_GTF2F1
Z-value: 0.81
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Transcription factors associated with MAZ_ZNF281_GTF2F1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF281 | hg19_v2_chr1_-_200379129_200379174 | 0.92 | 7.8e-02 | Click! |
| MAZ | hg19_v2_chr16_+_29817841_29817917 | -0.61 | 3.9e-01 | Click! |
| GTF2F1 | hg19_v2_chr19_-_6393216_6393229 | 0.40 | 6.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_46142615 Show fit | 0.66 |
ENST00000529734.1
ENST00000323180.6 |
PHD finger protein 21A |
|
| chr8_+_22457127 Show fit | 0.63 |
ENST00000289989.5
|
chromosome 8 open reading frame 58 |
|
| chr17_-_58469329 Show fit | 0.61 |
ENST00000393003.3
|
ubiquitin specific peptidase 32 |
|
| chr20_+_57466629 Show fit | 0.61 |
ENST00000371081.1
ENST00000338783.6 |
GNAS complex locus |
|
| chr2_+_121493717 Show fit | 0.55 |
ENST00000418323.1
|
GLI family zinc finger 2 |
|
| chr19_+_3224700 Show fit | 0.52 |
ENST00000292672.2
ENST00000541430.2 |
CUGBP, Elav-like family member 5 |
|
| chr19_+_55795493 Show fit | 0.50 |
ENST00000309383.1
|
BR serine/threonine kinase 1 |
|
| chr17_-_76628125 Show fit | 0.49 |
ENST00000586185.1
ENST00000591384.1 |
CTD-2357A8.3 |
|
| chr4_-_1107306 Show fit | 0.42 |
ENST00000433731.2
ENST00000333673.5 ENST00000382968.5 |
ring finger protein 212 |
|
| chr8_+_22457100 Show fit | 0.42 |
ENST00000409586.3
|
chromosome 8 open reading frame 58 |
Network of associatons between targets according to the STRING database.
First level regulatory network of MAZ_ZNF281_GTF2F1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 1.2 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
| 0.0 | 1.0 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.1 | 0.8 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.2 | 0.7 | GO:0060032 | notochord regression(GO:0060032) |
| 0.1 | 0.7 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 0.7 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.1 | 0.6 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.1 | 0.6 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.1 | 0.6 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 1.8 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 1.3 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 1.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 1.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.0 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.9 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 0.7 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.1 | 0.7 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.7 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 1.4 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.9 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.9 | GO:0061733 | peptide-lysine-N-acetyltransferase activity(GO:0061733) |
| 0.0 | 0.8 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.8 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.0 | 0.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 0.7 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 0.7 | GO:0051430 | corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.9 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.1 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 1.1 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.1 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.0 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 0.8 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.7 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 1.2 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.0 | 1.0 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.0 | 1.0 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.8 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.8 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 0.0 | 0.8 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.7 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.7 | REACTOME BOTULINUM NEUROTOXICITY | Genes involved in Botulinum neurotoxicity |
| 0.0 | 0.7 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |