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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for MAX_TFEB

Z-value: 0.75

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Transcription factors associated with MAX_TFEB

Gene Symbol Gene ID Gene Info
MAX
ENSG00000125952.14 MYC associated factor X
TFEB
ENSG00000112561.13 transcription factor EB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFEBhg19_v2_chr6_-_41673552_416736780.909.9e-02Click!
MAXhg19_v2_chr14_-_65569057_65569119-0.881.2e-01Click!

Activity profile of MAX_TFEB motif

Sorted Z-values of MAX_TFEB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_33385854 1.34 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr17_-_7137857 1.23 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr16_+_2570340 1.19 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr1_+_44440575 1.05 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr17_-_7137582 0.94 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr19_-_10764509 0.93 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr12_-_58146048 0.78 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4
cyclin-dependent kinase 4
chr1_-_11865982 0.74 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr19_-_36545649 0.71 ENST00000292894.1
THAP8
THAP domain containing 8
chr8_-_103876340 0.63 ENST00000518353.1
AZIN1
antizyme inhibitor 1
chr16_-_5083917 0.63 ENST00000312251.3
ENST00000381955.3
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr14_-_20922960 0.62 ENST00000553640.1
ENST00000488532.2
OSGEP
O-sialoglycoprotein endopeptidase
chr16_-_5083589 0.61 ENST00000563578.1
ENST00000562346.2
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr10_-_76995769 0.60 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr6_-_44225231 0.59 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr2_+_220042933 0.59 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr12_+_54332535 0.58 ENST00000243056.3
HOXC13
homeobox C13
chr10_-_76995675 0.56 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr7_+_150759634 0.55 ENST00000392826.2
ENST00000461735.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr3_+_19988736 0.55 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr9_-_131709858 0.53 ENST00000372586.3
DOLK
dolichol kinase
chr2_-_220042825 0.52 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr16_-_1525016 0.49 ENST00000262318.8
ENST00000448525.1
CLCN7
chloride channel, voltage-sensitive 7
chr6_-_43197189 0.49 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr16_-_28503327 0.48 ENST00000535392.1
ENST00000395653.4
CLN3
ceroid-lipofuscinosis, neuronal 3
chr14_-_20929624 0.48 ENST00000398020.4
ENST00000250489.4
TMEM55B
transmembrane protein 55B
chr17_+_62223320 0.46 ENST00000580828.1
ENST00000582965.1
SNORA76
small nucleolar RNA, H/ACA box 76
chr3_-_196987309 0.45 ENST00000453607.1
DLG1
discs, large homolog 1 (Drosophila)
chr10_+_99258625 0.45 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr12_-_58146128 0.45 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4
cyclin-dependent kinase 4
chr4_-_2935674 0.44 ENST00000514800.1
MFSD10
major facilitator superfamily domain containing 10
chr20_-_62493217 0.44 ENST00000601296.1
C20ORF135
C20ORF135
chr5_-_176730733 0.43 ENST00000504395.1
RAB24
RAB24, member RAS oncogene family
chr20_-_2821271 0.42 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr19_-_47734448 0.41 ENST00000439096.2
BBC3
BCL2 binding component 3
chr2_-_47572105 0.40 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
AC073283.4
chr12_-_49463753 0.40 ENST00000301068.6
RHEBL1
Ras homolog enriched in brain like 1
chr16_+_2570431 0.39 ENST00000563556.1
AMDHD2
amidohydrolase domain containing 2
chr19_+_1275917 0.39 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chr19_-_5680891 0.38 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr1_+_11796177 0.38 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
AGTRAP
angiotensin II receptor-associated protein
chr16_-_28503080 0.37 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr12_-_121342170 0.37 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr11_+_67159416 0.37 ENST00000307980.2
ENST00000544620.1
RAD9A
RAD9 homolog A (S. pombe)
chr11_+_57509020 0.36 ENST00000388857.4
ENST00000528798.1
C11orf31
chromosome 11 open reading frame 31
chr1_+_92414952 0.36 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT
bromodomain, testis-specific
chr11_+_65627974 0.36 ENST00000525768.1
MUS81
MUS81 structure-specific endonuclease subunit
chr1_+_11796126 0.36 ENST00000376637.3
AGTRAP
angiotensin II receptor-associated protein
chr4_-_100871506 0.36 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr17_+_6915798 0.35 ENST00000402093.1
RNASEK
ribonuclease, RNase K
chr13_+_113951607 0.35 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr17_+_6915730 0.35 ENST00000548577.1
RNASEK
ribonuclease, RNase K
chr1_-_154193091 0.34 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43
chromosome 1 open reading frame 43
chr19_+_49458107 0.34 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr19_-_40324767 0.33 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr19_-_11545920 0.33 ENST00000356392.4
ENST00000591179.1
CCDC151
coiled-coil domain containing 151
chr5_+_149865838 0.33 ENST00000519157.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr12_+_56110315 0.33 ENST00000548556.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr11_-_71814422 0.33 ENST00000278671.5
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr16_+_28985542 0.33 ENST00000567771.1
ENST00000568388.1
SPNS1
spinster homolog 1 (Drosophila)
chr3_-_178789220 0.33 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr19_-_41256207 0.32 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr6_-_33385655 0.32 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr19_+_41305330 0.31 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr2_-_47572207 0.31 ENST00000441997.1
AC073283.4
AC073283.4
chr19_+_14544099 0.31 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr3_+_183967409 0.31 ENST00000324557.4
ENST00000402825.3
ECE2
endothelin converting enzyme 2
chr15_-_72668805 0.31 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr8_-_144679264 0.31 ENST00000531953.1
ENST00000526133.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr16_+_28986085 0.31 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1
spinster homolog 1 (Drosophila)
chr5_+_150827143 0.31 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr1_-_155232221 0.31 ENST00000355379.3
SCAMP3
secretory carrier membrane protein 3
chr13_+_113951532 0.30 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr19_-_15236470 0.30 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr17_-_38256973 0.29 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr1_+_11333546 0.29 ENST00000376804.2
UBIAD1
UbiA prenyltransferase domain containing 1
chr16_+_57220049 0.29 ENST00000562439.1
RSPRY1
ring finger and SPRY domain containing 1
chr17_+_1627834 0.28 ENST00000419248.1
ENST00000418841.1
WDR81
WD repeat domain 81
chr11_+_57508825 0.28 ENST00000534355.1
C11orf31
chromosome 11 open reading frame 31
chr17_+_72428266 0.28 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr16_-_28503357 0.28 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chrX_+_153627231 0.28 ENST00000406022.2
RPL10
ribosomal protein L10
chr18_+_20715416 0.28 ENST00000580153.1
CABLES1
Cdk5 and Abl enzyme substrate 1
chr17_+_42148097 0.28 ENST00000269097.4
G6PC3
glucose 6 phosphatase, catalytic, 3
chr17_+_46970178 0.28 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr16_-_88923285 0.28 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr3_-_4508925 0.28 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
SUMF1
sulfatase modifying factor 1
chr19_-_41903161 0.27 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr3_+_51428704 0.27 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chrY_-_15591818 0.27 ENST00000382893.1
UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr11_-_1785139 0.27 ENST00000236671.2
CTSD
cathepsin D
chr7_+_99699280 0.27 ENST00000421755.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr7_+_4815238 0.26 ENST00000348624.4
ENST00000401897.1
AP5Z1
adaptor-related protein complex 5, zeta 1 subunit
chr12_-_108154705 0.26 ENST00000547188.1
PRDM4
PR domain containing 4
chr19_-_15236562 0.26 ENST00000263383.3
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr5_-_154230130 0.25 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chrX_-_100662881 0.25 ENST00000218516.3
GLA
galactosidase, alpha
chr19_+_7587491 0.25 ENST00000264079.6
MCOLN1
mucolipin 1
chr3_-_49395892 0.25 ENST00000419783.1
GPX1
glutathione peroxidase 1
chr7_+_99699179 0.25 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr17_+_6915902 0.25 ENST00000570898.1
ENST00000552842.1
RNASEK
ribonuclease, RNase K
chr6_-_33385870 0.25 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr17_-_18266818 0.25 ENST00000583780.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr11_+_62538775 0.25 ENST00000294168.3
ENST00000526261.1
TAF6L
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr15_+_75628232 0.25 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chr12_-_53625958 0.24 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr14_-_54420133 0.24 ENST00000559501.1
ENST00000558984.1
BMP4
bone morphogenetic protein 4
chr22_-_39268192 0.24 ENST00000216083.6
CBX6
chromobox homolog 6
chr11_+_61560348 0.24 ENST00000535723.1
ENST00000574708.1
FEN1
FADS2
flap structure-specific endonuclease 1
fatty acid desaturase 2
chr9_+_131709966 0.24 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr17_+_74732889 0.24 ENST00000591864.1
MFSD11
major facilitator superfamily domain containing 11
chr15_+_89182156 0.24 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr20_-_2821756 0.24 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr6_-_31763276 0.23 ENST00000440048.1
VARS
valyl-tRNA synthetase
chr2_-_198364552 0.23 ENST00000439605.1
ENST00000418022.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr19_-_49016847 0.23 ENST00000598924.1
CTC-273B12.10
CTC-273B12.10
chrX_+_23685653 0.23 ENST00000379331.3
PRDX4
peroxiredoxin 4
chr22_-_42343117 0.23 ENST00000407253.3
ENST00000215980.5
CENPM
centromere protein M
chr19_-_40854281 0.23 ENST00000392035.2
C19orf47
chromosome 19 open reading frame 47
chr19_+_6464243 0.23 ENST00000600229.1
ENST00000356762.3
CRB3
crumbs homolog 3 (Drosophila)
chr6_-_33385823 0.23 ENST00000494751.1
ENST00000374496.3
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr19_+_39903185 0.23 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr16_+_5121814 0.22 ENST00000262374.5
ENST00000586840.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr12_+_6644443 0.22 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr19_+_50016411 0.22 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_-_10426663 0.22 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
FDX1L
ferredoxin 1-like
chr7_+_100271355 0.22 ENST00000436220.1
ENST00000424361.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr11_+_67776012 0.22 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr22_+_31002779 0.22 ENST00000215838.3
TCN2
transcobalamin II
chr1_-_212873267 0.22 ENST00000243440.1
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr19_-_4670345 0.22 ENST00000599630.1
ENST00000262947.3
C19orf10
chromosome 19 open reading frame 10
chr9_-_34637806 0.21 ENST00000477726.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr7_+_100271446 0.21 ENST00000419828.1
ENST00000427895.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr22_+_31003133 0.21 ENST00000405742.3
TCN2
transcobalamin II
chr10_+_99344071 0.21 ENST00000370647.4
ENST00000370646.4
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr19_+_40854363 0.21 ENST00000599685.1
ENST00000392032.2
PLD3
phospholipase D family, member 3
chr15_+_75628394 0.21 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr19_+_40854559 0.21 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
PLD3
phospholipase D family, member 3
chr16_-_1401799 0.21 ENST00000007390.2
TSR3
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr1_-_153940097 0.21 ENST00000413622.1
ENST00000310483.6
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr3_+_72201910 0.21 ENST00000469178.1
ENST00000485404.1
LINC00870
long intergenic non-protein coding RNA 870
chr11_-_36310958 0.21 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9
COMM domain containing 9
chr7_+_2559399 0.21 ENST00000222725.5
ENST00000359574.3
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_10093188 0.21 ENST00000377153.1
UBE4B
ubiquitination factor E4B
chr15_+_75628419 0.21 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMMD4
COMM domain containing 4
chr6_+_42018614 0.21 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr16_+_5083950 0.21 ENST00000588623.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr2_-_85829780 0.21 ENST00000334462.5
TMEM150A
transmembrane protein 150A
chr9_-_140009130 0.21 ENST00000497375.1
ENST00000371579.2
DPP7
dipeptidyl-peptidase 7
chr22_+_35776828 0.20 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr7_+_99070527 0.20 ENST00000379724.3
ZNF789
zinc finger protein 789
chr22_-_20850070 0.20 ENST00000440659.2
ENST00000458248.1
ENST00000443285.1
ENST00000444967.1
ENST00000451553.1
ENST00000431430.1
KLHL22
kelch-like family member 22
chr6_-_31612808 0.20 ENST00000438149.1
BAG6
BCL2-associated athanogene 6
chr1_-_154193009 0.20 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43
chromosome 1 open reading frame 43
chr17_-_37886752 0.20 ENST00000577810.1
MIEN1
migration and invasion enhancer 1
chr22_+_21996549 0.20 ENST00000248958.4
SDF2L1
stromal cell-derived factor 2-like 1
chr1_-_111991850 0.20 ENST00000411751.2
WDR77
WD repeat domain 77
chr19_-_12833164 0.20 ENST00000356861.5
TNPO2
transportin 2
chr19_-_51307894 0.20 ENST00000597705.1
ENST00000391812.1
C19orf48
chromosome 19 open reading frame 48
chr17_-_4607335 0.20 ENST00000570571.1
ENST00000575101.1
ENST00000436683.2
ENST00000574876.1
PELP1
proline, glutamate and leucine rich protein 1
chr19_-_5720248 0.20 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr17_-_79520135 0.20 ENST00000541246.1
ENST00000544302.1
C17orf70
chromosome 17 open reading frame 70
chr3_-_49395705 0.20 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr1_-_207119738 0.19 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr7_-_44530479 0.19 ENST00000355451.7
NUDCD3
NudC domain containing 3
chr17_+_46018872 0.19 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
PNPO
pyridoxamine 5'-phosphate oxidase
chr3_+_50654821 0.19 ENST00000457064.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr19_-_47290535 0.19 ENST00000412532.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr11_-_66725837 0.19 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC
pyruvate carboxylase
chr16_-_67190152 0.19 ENST00000486556.1
TRADD
TNFRSF1A-associated via death domain
chr16_+_28986134 0.19 ENST00000352260.7
SPNS1
spinster homolog 1 (Drosophila)
chr19_+_45681997 0.19 ENST00000433642.2
BLOC1S3
biogenesis of lysosomal organelles complex-1, subunit 3
chr20_-_3748363 0.19 ENST00000217195.8
C20orf27
chromosome 20 open reading frame 27
chr17_+_46970134 0.19 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr7_+_148959262 0.19 ENST00000434415.1
ZNF783
zinc finger family member 783
chr7_+_150065879 0.19 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
REPIN1
ZNF775
replication initiator 1
zinc finger protein 775
chr10_-_99258135 0.19 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr15_-_72668185 0.19 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA
hexosaminidase A (alpha polypeptide)
chr10_-_126849626 0.19 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr9_+_133978190 0.19 ENST00000372312.3
AIF1L
allograft inflammatory factor 1-like
chr12_+_113623325 0.18 ENST00000549621.1
ENST00000548278.1
ENST00000552495.1
C12orf52
RBPJ interacting and tubulin associated 1
chr19_-_45909585 0.18 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr17_+_72428218 0.18 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr3_-_49967292 0.18 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chr22_-_20850128 0.18 ENST00000328879.4
KLHL22
kelch-like family member 22
chr2_-_85829811 0.18 ENST00000306353.3
TMEM150A
transmembrane protein 150A
chr3_-_49761337 0.18 ENST00000535833.1
ENST00000308388.6
ENST00000480687.1
ENST00000308375.6
AMIGO3
GMPPB
adhesion molecule with Ig-like domain 3
GDP-mannose pyrophosphorylase B
chr19_+_36545781 0.18 ENST00000388999.3
WDR62
WD repeat domain 62
chr11_-_71814276 0.18 ENST00000538404.1
ENST00000535107.1
ENST00000545249.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr5_+_149865377 0.18 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr19_-_45681482 0.18 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
TRAPPC6A
trafficking protein particle complex 6A
chr12_+_51633061 0.18 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr3_-_49055991 0.18 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
DALRD3
DALR anticodon binding domain containing 3
chr19_+_41256764 0.18 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr7_+_99746514 0.18 ENST00000341942.5
ENST00000441173.1
LAMTOR4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr22_-_42765174 0.18 ENST00000432473.1
ENST00000412060.1
ENST00000424852.1
Z83851.1
Z83851.1
chr8_+_103876528 0.18 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2
HCG15011, isoform CRA_a; Protein LOC100996457
chr4_+_76439649 0.18 ENST00000507557.1
THAP6
THAP domain containing 6
chr9_-_19127474 0.18 ENST00000380465.3
ENST00000380464.3
ENST00000411567.1
ENST00000276914.2
PLIN2
perilipin 2
chr6_-_33385902 0.18 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)

Network of associatons between targets according to the STRING database.

First level regulatory network of MAX_TFEB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 1.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 1.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.6 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.2 1.2 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.2 0.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 0.5 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.2 0.6 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 0.8 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 0.5 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.4 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.8 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.3 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.3 GO:1902512 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.4 GO:1904482 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.3 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.1 0.4 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 0.8 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1 1.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.5 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.2 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.4 GO:0009233 menaquinone metabolic process(GO:0009233)
0.1 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.2 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 0.3 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.4 GO:0010159 specification of organ position(GO:0010159)
0.0 0.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.2 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.2 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.6 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0052330 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.0 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.7 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.0 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.8 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.5 GO:0006477 protein sulfation(GO:0006477)
0.0 1.2 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.3 GO:0050893 sensory processing(GO:0050893)
0.0 0.4 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.0 0.1 GO:0006218 uridine catabolic process(GO:0006218)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.5 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727) flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.4 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.5 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0006818 hydrogen transport(GO:0006818) proton transport(GO:0015992)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997) D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.2 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:2000254 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) regulation of male germ cell proliferation(GO:2000254)
0.0 0.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.2 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.0 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.0 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.0 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.0 0.0 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.0 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.0 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.0 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.0 GO:0018013 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.6 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.5 GO:0097413 Lewy body(GO:0097413)
0.0 0.5 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.6 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.4 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.8 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.0 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 2.9 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 1.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.2 0.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 0.8 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 0.5 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.4 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.7 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.8 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.9 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.2 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.1 2.0 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.2 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.2 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.5 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.4 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.4 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 2.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 1.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 1.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 2.4 GO:0005507 copper ion binding(GO:0005507)
0.0 0.6 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565) galactosidase activity(GO:0015925)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.0 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.0 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0019213 deacetylase activity(GO:0019213)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions