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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
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Results for MAFB
Z-value: 1.11
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Transcription factors associated with MAFB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MAFB | hg19_v2_chr20_-_39317868_39317884 | -0.23 | 7.7e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of MAFB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 1.7 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.1 | 1.0 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.1 | 0.8 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.0 | 0.7 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 0.1 | 0.6 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.1 | 0.6 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.1 | 0.6 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.0 | 0.6 | GO:0071174 | mitotic spindle checkpoint(GO:0071174) |
| 0.1 | 0.5 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.2 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 0.9 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.0 | 0.9 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 0.8 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.1 | 0.7 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.1 | 0.7 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.7 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 0.6 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.0 | 0.6 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 1.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 1.1 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 1.0 | GO:0051430 | corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.0 | 1.0 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.9 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.0 | 0.9 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.8 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.8 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.6 | GO:0004359 | glutaminase activity(GO:0004359) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.0 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 0.9 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.7 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.6 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.6 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.5 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 0.9 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.9 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.8 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.8 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.8 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.0 | 0.6 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.0 | 0.6 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 0.6 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.0 | 0.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |