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A549 cells infected with IAV Analysis Results (GEO series: GSE147507)

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Results for MAFA

Z-value: 0.31

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Transcription factors associated with MAFA

Gene Symbol Gene ID Gene Info
MAFA
ENSG00000182759.3 MAF bZIP transcription factor A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFAhg19_v2_chr8_-_144512576_1445125760.831.7e-01Click!

Activity profile of MAFA motif

Sorted Z-values of MAFA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_58074069 0.25 ENST00000570065.1
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr7_-_150754935 0.11 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr12_+_21654714 0.11 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr4_+_74606223 0.10 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr15_-_66858298 0.10 ENST00000537670.1
LCTL
lactase-like
chr19_+_21541732 0.10 ENST00000311015.3
ZNF738
zinc finger protein 738
chr6_-_74161977 0.08 ENST00000370318.1
ENST00000370315.3
MB21D1
Mab-21 domain containing 1
chr22_+_22556057 0.07 ENST00000390286.2
IGLV11-55
immunoglobulin lambda variable 11-55 (non-functional)
chr5_-_94620239 0.07 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr7_-_151433342 0.07 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr14_+_36295638 0.07 ENST00000543183.1
BRMS1L
breast cancer metastasis-suppressor 1-like
chr11_+_777562 0.07 ENST00000530083.1
AP006621.5
Protein LOC100506518
chr10_+_135122906 0.07 ENST00000368554.4
ZNF511
zinc finger protein 511
chr1_+_221054411 0.07 ENST00000427693.1
HLX
H2.0-like homeobox
chr10_-_135171178 0.06 ENST00000368551.1
FUOM
fucose mutarotase
chr19_-_50464338 0.06 ENST00000426971.2
ENST00000447370.2
SIGLEC11
sialic acid binding Ig-like lectin 11
chr2_+_191745560 0.06 ENST00000338435.4
GLS
glutaminase
chr11_+_107461948 0.06 ENST00000265840.7
ENST00000443271.2
ELMOD1
ELMO/CED-12 domain containing 1
chr14_+_24605389 0.06 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr5_-_114505624 0.06 ENST00000513154.1
TRIM36
tripartite motif containing 36
chr6_+_22221010 0.06 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr3_+_196439170 0.05 ENST00000392391.3
ENST00000314118.4
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr14_+_50779029 0.05 ENST00000245448.6
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr3_+_140770183 0.05 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr2_+_118846008 0.05 ENST00000245787.4
INSIG2
insulin induced gene 2
chr16_-_46865047 0.05 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr10_+_124221036 0.05 ENST00000368984.3
HTRA1
HtrA serine peptidase 1
chr16_-_46865286 0.05 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr19_+_54641444 0.05 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chr1_-_32403370 0.05 ENST00000534796.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr5_+_139739772 0.04 ENST00000506757.2
ENST00000230993.6
ENST00000506545.1
ENST00000432095.2
ENST00000507527.1
SLC4A9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr7_-_155160629 0.04 ENST00000378120.5
BLACE
B-cell acute lymphoblastic leukemia expressed
chr19_-_37958318 0.04 ENST00000316950.6
ENST00000591710.1
ZNF569
zinc finger protein 569
chr19_+_12949251 0.04 ENST00000251472.4
MAST1
microtubule associated serine/threonine kinase 1
chr2_+_103236004 0.04 ENST00000233969.2
SLC9A2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr16_+_28996364 0.04 ENST00000564277.1
LAT
linker for activation of T cells
chr5_+_138629389 0.04 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
MATR3
matrin 3
chr9_+_2622085 0.04 ENST00000382099.2
VLDLR
very low density lipoprotein receptor
chr20_-_43743790 0.04 ENST00000307971.4
ENST00000372789.4
WFDC5
WAP four-disulfide core domain 5
chr6_+_97372645 0.04 ENST00000536676.1
ENST00000544166.1
KLHL32
kelch-like family member 32
chr6_+_7727030 0.04 ENST00000283147.6
BMP6
bone morphogenetic protein 6
chr3_+_196439275 0.04 ENST00000296333.5
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr19_+_39647271 0.04 ENST00000599657.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr11_+_33563821 0.03 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr19_-_43099070 0.03 ENST00000244336.5
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr1_-_32403903 0.03 ENST00000344035.6
ENST00000356536.3
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr13_-_28194541 0.03 ENST00000316334.3
LNX2
ligand of numb-protein X 2
chr3_+_107241882 0.03 ENST00000416476.2
BBX
bobby sox homolog (Drosophila)
chrX_-_92928557 0.03 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr1_-_45956868 0.03 ENST00000451835.2
TESK2
testis-specific kinase 2
chr13_-_103426081 0.03 ENST00000376022.1
ENST00000376021.4
TEX30
testis expressed 30
chr4_+_2470664 0.03 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
RNF4
ring finger protein 4
chr17_-_39781054 0.03 ENST00000463128.1
KRT17
keratin 17
chr5_+_138629628 0.03 ENST00000508689.1
ENST00000514528.1
MATR3
matrin 3
chr4_+_72052964 0.03 ENST00000264485.5
ENST00000425175.1
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr4_-_22517620 0.03 ENST00000502482.1
ENST00000334304.5
GPR125
G protein-coupled receptor 125
chr5_+_138629337 0.03 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
MATR3
matrin 3
chr16_+_56225248 0.03 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr11_+_118826999 0.03 ENST00000264031.2
UPK2
uroplakin 2
chr20_-_23066953 0.03 ENST00000246006.4
CD93
CD93 molecule
chr6_+_42896865 0.03 ENST00000372836.4
ENST00000394142.3
CNPY3
canopy FGF signaling regulator 3
chr4_+_72053017 0.03 ENST00000351898.6
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr17_+_41363854 0.03 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr15_-_23086259 0.03 ENST00000538684.1
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr6_+_97372734 0.03 ENST00000539200.1
KLHL32
kelch-like family member 32
chr15_+_90744533 0.03 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr1_+_202091980 0.03 ENST00000367282.5
GPR37L1
G protein-coupled receptor 37 like 1
chr2_-_30143525 0.03 ENST00000431873.1
ALK
anaplastic lymphoma receptor tyrosine kinase
chr1_+_78354175 0.03 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
NEXN
nexilin (F actin binding protein)
chr4_+_6784401 0.03 ENST00000425103.1
ENST00000307659.5
KIAA0232
KIAA0232
chr10_-_70231639 0.03 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2
DNA replication helicase/nuclease 2
chr1_+_174769006 0.02 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr16_+_70258261 0.02 ENST00000594734.1
FKSG63
FKSG63
chr4_-_10118348 0.02 ENST00000502702.1
WDR1
WD repeat domain 1
chr8_-_63998590 0.02 ENST00000260116.4
TTPA
tocopherol (alpha) transfer protein
chr7_-_30029367 0.02 ENST00000242059.5
SCRN1
secernin 1
chr3_-_196439065 0.02 ENST00000399942.4
ENST00000409690.3
CEP19
centrosomal protein 19kDa
chr12_+_79258444 0.02 ENST00000261205.4
SYT1
synaptotagmin I
chrX_-_153141302 0.02 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM
L1 cell adhesion molecule
chr10_-_135171510 0.02 ENST00000278025.4
ENST00000368552.3
FUOM
fucose mutarotase
chr11_-_64660916 0.02 ENST00000413053.1
MIR194-2
microRNA 194-2
chr12_+_54943134 0.02 ENST00000243052.3
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr12_+_108525517 0.02 ENST00000332082.4
WSCD2
WSC domain containing 2
chr19_-_33182616 0.02 ENST00000592431.1
CTD-2538C1.2
CTD-2538C1.2
chr21_+_44589118 0.02 ENST00000291554.2
CRYAA
crystallin, alpha A
chr14_+_36295504 0.02 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr15_-_23086394 0.02 ENST00000337435.4
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr6_+_97372596 0.02 ENST00000369261.4
KLHL32
kelch-like family member 32
chr3_-_131736593 0.02 ENST00000514999.1
CPNE4
copine IV
chr1_-_13331692 0.02 ENST00000353410.5
ENST00000376173.3
PRAMEF3
PRAME family member 3
chr13_-_103426112 0.02 ENST00000376032.4
ENST00000376029.3
TEX30
testis expressed 30
chr16_-_89119355 0.02 ENST00000537498.1
CTD-2555A7.2
CTD-2555A7.2
chr10_-_49701686 0.02 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr14_+_81421355 0.02 ENST00000541158.2
TSHR
thyroid stimulating hormone receptor
chr13_+_53226963 0.02 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr4_+_106067943 0.02 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
TET2
tet methylcytosine dioxygenase 2
chr2_+_33172221 0.01 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr19_-_2050852 0.01 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr5_+_138629417 0.01 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3
matrin 3
chr14_+_24600484 0.01 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr2_+_191745535 0.01 ENST00000320717.3
GLS
glutaminase
chr17_-_41623009 0.01 ENST00000393664.2
ETV4
ets variant 4
chr1_-_153517473 0.01 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr4_+_15005391 0.01 ENST00000507071.1
ENST00000345451.3
ENST00000259997.5
ENST00000382395.3
ENST00000382401.3
CPEB2
cytoplasmic polyadenylation element binding protein 2
chr7_-_108168580 0.01 ENST00000453085.1
PNPLA8
patatin-like phospholipase domain containing 8
chr11_+_33563618 0.01 ENST00000526400.1
KIAA1549L
KIAA1549-like
chr1_-_38325256 0.01 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr14_+_81421861 0.01 ENST00000298171.2
TSHR
thyroid stimulating hormone receptor
chr6_+_116692102 0.01 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr7_-_30029574 0.01 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
SCRN1
secernin 1
chr19_+_18451439 0.01 ENST00000597431.2
PGPEP1
pyroglutamyl-peptidase I
chr1_+_90286562 0.01 ENST00000525774.1
ENST00000337338.5
LRRC8D
leucine rich repeat containing 8 family, member D
chr9_-_127905736 0.01 ENST00000336505.6
ENST00000373549.4
SCAI
suppressor of cancer cell invasion
chr10_+_102505954 0.01 ENST00000556085.1
ENST00000427256.1
PAX2
paired box 2
chr1_+_221054584 0.01 ENST00000549319.1
HLX
H2.0-like homeobox
chr6_+_89791507 0.01 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr8_+_85095497 0.01 ENST00000522455.1
ENST00000521695.1
RALYL
RALY RNA binding protein-like
chr1_-_45956822 0.01 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr1_+_66458072 0.01 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_+_85095553 0.01 ENST00000521268.1
RALYL
RALY RNA binding protein-like
chr1_+_206858328 0.01 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr8_+_145438870 0.01 ENST00000527931.1
FAM203B
family with sequence similarity 203, member B
chr10_-_79397391 0.01 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr11_+_111411384 0.01 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
LAYN
layilin
chrX_+_74493896 0.01 ENST00000373383.4
ENST00000373379.1
UPRT
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr7_-_30029328 0.01 ENST00000425819.2
ENST00000409570.1
SCRN1
secernin 1
chr13_+_28194873 0.01 ENST00000302979.3
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr19_-_51141196 0.01 ENST00000338916.4
SYT3
synaptotagmin III
chr17_-_17109579 0.00 ENST00000321560.3
PLD6
phospholipase D family, member 6
chr4_-_151936416 0.00 ENST00000510413.1
ENST00000507224.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr19_+_6740888 0.00 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr12_+_79258547 0.00 ENST00000457153.2
SYT1
synaptotagmin I
chrX_-_153141434 0.00 ENST00000407935.2
ENST00000439496.1
L1CAM
L1 cell adhesion molecule
chr16_-_67514982 0.00 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr11_+_111412053 0.00 ENST00000530962.1
LAYN
layilin
chr15_-_90456114 0.00 ENST00000398333.3
C15orf38-AP3S2
C15orf38-AP3S2 readthrough
chr6_+_147525541 0.00 ENST00000367481.3
ENST00000546097.1
STXBP5
syntaxin binding protein 5 (tomosyn)
chr6_-_143832820 0.00 ENST00000002165.6
FUCA2
fucosidase, alpha-L- 2, plasma
chr15_+_98503922 0.00 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr4_-_151936865 0.00 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr2_-_26205550 0.00 ENST00000405914.1
KIF3C
kinesin family member 3C

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)