Project
A549 cells infected with IAV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for KLF16_SP2
Z-value: 1.66
Motif logo
Transcription factors associated with KLF16_SP2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| KLF16 | hg19_v2_chr19_-_1863567_1863586 | 0.98 | 2.5e-02 | Click! |
| SP2 | hg19_v2_chr17_+_45973516_45973618 | 0.40 | 6.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_47778119 Show fit | 2.98 |
ENST00000552360.2
|
proline rich 24 |
|
| chr19_+_54694119 Show fit | 2.79 |
ENST00000456872.1
ENST00000302937.4 ENST00000429671.2 |
TSEN34 tRNA splicing endonuclease subunit |
|
| chr19_-_1863567 Show fit | 2.55 |
ENST00000250916.4
|
Kruppel-like factor 16 |
|
| chr9_+_130922537 Show fit | 2.51 |
ENST00000372994.1
|
chromosome 9 open reading frame 16 |
|
| chr14_-_21566731 Show fit | 2.28 |
ENST00000360947.3
|
zinc finger protein 219 |
|
| chr19_+_6373715 Show fit | 2.26 |
ENST00000599849.1
|
alkB, alkylation repair homolog 7 (E. coli) |
|
| chr19_+_50433476 Show fit | 2.02 |
ENST00000596658.1
|
activating transcription factor 5 |
|
| chr8_-_145691031 Show fit | 1.80 |
ENST00000424149.2
ENST00000530637.1 ENST00000306145.5 |
cysteine/histidine-rich 1 |
|
| chr19_+_6373482 Show fit | 1.78 |
ENST00000596657.1
|
alkB, alkylation repair homolog 7 (E. coli) |
|
| chr8_-_145754428 Show fit | 1.77 |
ENST00000527462.1
ENST00000313465.5 ENST00000524821.1 |
chromosome 8 open reading frame 82 |
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF16_SP2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 5.0 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 4.6 | GO:0050655 | dermatan sulfate proteoglycan metabolic process(GO:0050655) |
| 0.7 | 4.4 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
| 1.1 | 4.2 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 0.0 | 3.7 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.3 | 3.6 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 0.0 | 3.4 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.2 | 3.1 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) |
| 0.1 | 2.8 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.1 | 2.8 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 85.0 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.1 | 13.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 11.2 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 10.0 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.1 | 5.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 4.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 4.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.8 | 4.2 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.2 | 3.6 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 3.0 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 5.0 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.0 | 4.9 | GO:0051213 | dioxygenase activity(GO:0051213) |
| 0.7 | 3.9 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.4 | 3.9 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.4 | 3.7 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.2 | 3.3 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.2 | 2.9 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.0 | 2.8 | GO:0098531 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.1 | 2.7 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.2 | 2.6 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 4.4 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.1 | 4.3 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 3.8 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 3.7 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 3.3 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 2.8 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 2.8 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 2.1 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 1.7 | PID ARF 3PATHWAY | Arf1 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.3 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 6.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 5.0 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 4.9 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 3.8 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 3.7 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 3.7 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.2 | 3.1 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 3.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 2.6 | REACTOME SIGNALING BY NOTCH3 | Genes involved in Signaling by NOTCH3 |